Mp2g16090.1

Protein

Length

1,126 amino acids

Protein family membership

Phytochrome (IPR001294)
- Phytochrome A/B/C/D/E (IPR012129)

Homologous superfamilies

Homologous superfamily
73 - 186
PAS domain superfamily (IPR035965)
403 - 576
Phytochrome, PHY domain (IPR043150)
618 - 727
PAS domain superfamily (IPR035965)
761 - 867
PAS domain superfamily (IPR035965)
953 - 1,115
Histidine kinase/HSP90-like ATPase superfamily (IPR036890)
Homologous superfamily
190 - 559
GAF-like domain superfamily (IPR029016)

1 200 400 600 800 1000 1126

Domains and repeats

Domain
68 - 184
PAS fold-2 (IPR013654)
217 - 408
GAF domain (IPR003018)
Phytochrome chromophore attachment domain (IPR016132)
411 - 584
Phytochrome, central region (IPR013515)
687 - 743
PAS-associated, C-terminal (IPR000700)
891 - 955
Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (IPR003661)
1,003 - 1,118
Histidine kinase/HSP90-like ATPase (IPR003594)
Domain
613 - 735
PAS domain (IPR000014)
PAS fold (IPR013767)
746 - 869
PAS domain (IPR000014)
PAS fold (IPR013767)
898 - 1,118
Histidine kinase domain (IPR005467)

1 200 400 600 800 1000 1126

Detailed signature matches

IPR035965

PAS domain superfamily
1. SSF55785 (PYP-like ...)
  
  73 - 186
  
  SUPERFAMILY
  SSF55785 (PYP-like sensor domain (PAS domain))
  
  761 - 867
  
  SUPERFAMILY
  SSF55785 (PYP-like sensor domain (PAS domain))
  
  618 - 727
  
  SUPERFAMILY
  SSF55785 (PYP-like sensor domain (PAS domain))
IPR029016

GAF-like domain superfamily
1. G3DSA:3.30.45...
  
  321 - 402
  
  GENE3D
  G3DSA:3.30.450.40 (G3DSA:3.30.450.40)
  
  522 - 559
  
  GENE3D
  G3DSA:3.30.450.40 (G3DSA:3.30.450.40)
  
  190 - 294
  
  GENE3D
  G3DSA:3.30.450.40 (G3DSA:3.30.450.40)
IPR043150

Phytochrome, PHY domain
1. G3DSA:3.30.45...
  
  560 - 576
  
  GENE3D
  G3DSA:3.30.450.270 (G3DSA:3.30.450.270)
  
  403 - 521
  
  GENE3D
  G3DSA:3.30.450.270 (G3DSA:3.30.450.270)
IPR036890

Histidine kinase/HSP90-like ATPase superfamily
1. G3DSA:3.30.56...
  
  953 - 1,105
  
  GENE3D
  G3DSA:3.30.565.10 (G3DSA:3.30.565.10)
2. SSF55874 (ATPase do...)
  
  970 - 1,115
  
  SUPERFAMILY
  SSF55874 (ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase)
IPR001294

Phytochrome
1. PR01033 (PHYTOCHROME)
  
  513 - 532
  
  PRINTS
  PR01033 (PHYTOCHROME)
  
  616 - 632
  
  PRINTS
  PR01033 (PHYTOCHROME)
  
  317 - 338
  
  PRINTS
  PR01033 (PHYTOCHROME)
  
  132 - 154
  
  PRINTS
  PR01033 (PHYTOCHROME)
  
  635 - 650
  
  PRINTS
  PR01033 (PHYTOCHROME)
  
  232 - 251
  
  PRINTS
  PR01033 (PHYTOCHROME)
  
  729 - 749
  
  PRINTS
  PR01033 (PHYTOCHROME)
  
  546 - 564
  
  PRINTS
  PR01033 (PHYTOCHROME)
  
  428 - 448
  
  PRINTS
  PR01033 (PHYTOCHROME)
  
  709 - 726
  
  PRINTS
  PR01033 (PHYTOCHROME)
IPR012129

Phytochrome A/B/C/D/E
1. PIRSF000084 (Phytoc...)
  
  1 - 1,123
  
  PIRSF
  PIRSF000084 (Phytochrome_conventional)
IPR013654

PAS fold-2
1. PF08446 (PAS_2)
  
  68 - 184
  
  Pfam
  PF08446 (PAS_2)
IPR003018

GAF domain
1. SM00065 (gaf_1)
  
  217 - 408
  
  SMART
  SM00065 (gaf_1)
2. PF01590 (GAF)
  
  217 - 398
  
  Pfam
  PF01590 (GAF)
IPR016132

Phytochrome chromophore attachment domain
1. PS50046 (PHYTOCHROME_2)
  
  217 - 388
  
  PROSITE profiles
  PS50046 (PHYTOCHROME_2)
IPR013515

Phytochrome, central region
1. PF00360 (PHY)
  
  411 - 584
  
  Pfam
  PF00360 (PHY)
IPR000014

PAS domain
1. PS50112 (PAS)
  
  747 - 799
  
  PROSITE profiles
  PS50112 (PAS)
  
  613 - 684
  
  PROSITE profiles
  PS50112 (PAS)
2. SM00091 (pas_2)
  
  615 - 682
  
  SMART
  SM00091 (pas_2)
  
  746 - 815
  
  SMART
  SM00091 (pas_2)
3. cd00130 (PAS)
  
  624 - 731
  
  CDD
  cd00130 (PAS)
  
  758 - 869
  
  CDD
  cd00130 (PAS)
4. TIGR00229
  
  620 - 735
  
  TIGRFAMs
  TIGR00229 (TIGR00229)
IPR013767

PAS fold
1. PF00989 (PAS)
  
  747 - 869
  
  Pfam
  PF00989 (PAS)
  
  616 - 731
  
  Pfam
  PF00989 (PAS)
IPR000700

PAS-associated, C-terminal
1. PS50113 (PAC)
  
  687 - 743
  
  PROSITE profiles
  PS50113 (PAC)
IPR003661

Signal transduction histidine kinase, dimerisation/phosphoacceptor domain
1. cd00082 (HisKA)
  
  891 - 947
  
  CDD
  cd00082 (HisKA)
2. SM00388 (HisKA_10)
  
  891 - 955
  
  SMART
  SM00388 (HisKA_10)
3. PF00512 (HisKA)
  
  892 - 955
  
  Pfam
  PF00512 (HisKA)
IPR005467

Histidine kinase domain
1. PS50109 (HIS_KIN)
  
  898 - 1,118
  
  PROSITE profiles
  PS50109 (HIS_KIN)
IPR003594

Histidine kinase/HSP90-like ATPase
1. PF02518 (HATPase_c)
  
  1,003 - 1,112
  
  Pfam
  PF02518 (HATPase_c)
2. SM00387 (HKATPase_4)
  
  1,003 - 1,118
  
  SMART
  SM00387 (HKATPase_4)
IPR013516

Phytochrome chromophore binding site
1. PS00245 (PHYTOCHROME_1)
  
  317 - 326
  
  PROSITE patterns
  PS00245 (PHYTOCHROME_1)

no IPR

Unintegrated signatures

G3DSA:1.10.28...

898 - 952

GENE3D
G3DSA:1.10.287.130 (G3DSA:1.10.287.130)
G3DSA:3.30.45...

612 - 735

GENE3D
G3DSA:3.30.450.20 (G3DSA:3.30.450.20)

760 - 874

GENE3D
G3DSA:3.30.450.20 (G3DSA:3.30.450.20)

77 - 189

GENE3D
G3DSA:3.30.450.20 (G3DSA:3.30.450.20)

295 - 320

GENE3D
G3DSA:3.30.450.20 (G3DSA:3.30.450.20)
PTHR43719 (TWO-COMP...)

2 - 1,118

PANTHER
PTHR43719 (TWO-COMPONENT HISTIDINE KINASE)
PTHR43719:SF4 (PHYT...)

2 - 1,118

PANTHER
PTHR43719:SF4 (PHYTOCHROME C)
SSF55781 (GAF domai...)

197 - 395

SUPERFAMILY
SSF55781 (GAF domain-like)

406 - 584

SUPERFAMILY
SSF55781 (GAF domain-like)
cd16932 (HATPase_Ph...)

1,002 - 1,114

CDD
cd16932 (HATPase_Phy-like)

Residue annotation

putative active si...

640W

putative active site
640W, 644V, 650L, 664L, 665A, 666L, 667E, 693L, 702K
CDD
cd00130 (PAS)

644V

putative active site
640W, 644V, 650L, 664L, 665A, 666L, 667E, 693L, 702K
CDD
cd00130 (PAS)

650L

putative active site
640W, 644V, 650L, 664L, 665A, 666L, 667E, 693L, 702K
CDD
cd00130 (PAS)

664L

putative active site
640W, 644V, 650L, 664L, 665A, 666L, 667E, 693L, 702K
CDD
cd00130 (PAS)

665A

putative active site
640W, 644V, 650L, 664L, 665A, 666L, 667E, 693L, 702K
CDD
cd00130 (PAS)

666L

putative active site
640W, 644V, 650L, 664L, 665A, 666L, 667E, 693L, 702K
CDD
cd00130 (PAS)

667E

putative active site
640W, 644V, 650L, 664L, 665A, 666L, 667E, 693L, 702K
CDD
cd00130 (PAS)

693L

putative active site
640W, 644V, 650L, 664L, 665A, 666L, 667E, 693L, 702K
CDD
cd00130 (PAS)

702K

putative active site
640W, 644V, 650L, 664L, 665A, 666L, 667E, 693L, 702K
CDD
cd00130 (PAS)
heme pocket cd00130

660L

heme pocket
660L, 665A, 673V, 676L, 677L, 709V, 711A
CDD
cd00130 (PAS)

665A

heme pocket
660L, 665A, 673V, 676L, 677L, 709V, 711A
CDD
cd00130 (PAS)

673V

heme pocket
660L, 665A, 673V, 676L, 677L, 709V, 711A
CDD
cd00130 (PAS)

676L

heme pocket
660L, 665A, 673V, 676L, 677L, 709V, 711A
CDD
cd00130 (PAS)

677L

heme pocket
660L, 665A, 673V, 676L, 677L, 709V, 711A
CDD
cd00130 (PAS)

709V

heme pocket
660L, 665A, 673V, 676L, 677L, 709V, 711A
CDD
cd00130 (PAS)

711A

heme pocket
660L, 665A, 673V, 676L, 677L, 709V, 711A
CDD
cd00130 (PAS)
putative active si...

774W

putative active site
774W, 778M, 784W, 797E, 798I, 799F, 800G, 837F, 842G
CDD
cd00130 (PAS)

778M

putative active site
774W, 778M, 784W, 797E, 798I, 799F, 800G, 837F, 842G
CDD
cd00130 (PAS)

784W

putative active site
774W, 778M, 784W, 797E, 798I, 799F, 800G, 837F, 842G
CDD
cd00130 (PAS)

797E

putative active site
774W, 778M, 784W, 797E, 798I, 799F, 800G, 837F, 842G
CDD
cd00130 (PAS)

798I

putative active site
774W, 778M, 784W, 797E, 798I, 799F, 800G, 837F, 842G
CDD
cd00130 (PAS)

799F

putative active site
774W, 778M, 784W, 797E, 798I, 799F, 800G, 837F, 842G
CDD
cd00130 (PAS)

800G

putative active site
774W, 778M, 784W, 797E, 798I, 799F, 800G, 837F, 842G
CDD
cd00130 (PAS)

837F

putative active site
774W, 778M, 784W, 797E, 798I, 799F, 800G, 837F, 842G
CDD
cd00130 (PAS)

842G

putative active site
774W, 778M, 784W, 797E, 798I, 799F, 800G, 837F, 842G
CDD
cd00130 (PAS)
heme pocket cd00130

794L

heme pocket
794L, 798I, 817F, 820V, 821L, 849L, 851A
CDD
cd00130 (PAS)

798I

heme pocket
794L, 798I, 817F, 820V, 821L, 849L, 851A
CDD
cd00130 (PAS)

817F

heme pocket
794L, 798I, 817F, 820V, 821L, 849L, 851A
CDD
cd00130 (PAS)

820V

heme pocket
794L, 798I, 817F, 820V, 821L, 849L, 851A
CDD
cd00130 (PAS)

821L

heme pocket
794L, 798I, 817F, 820V, 821L, 849L, 851A
CDD
cd00130 (PAS)

849L

heme pocket
794L, 798I, 817F, 820V, 821L, 849L, 851A
CDD
cd00130 (PAS)

851A

heme pocket
794L, 798I, 817F, 820V, 821L, 849L, 851A
CDD
cd00130 (PAS)
dimer interface cd...

895E

dimer interface
895E, 899I, 903I, 906P, 910I, 913T, 929F, 933S, 936C, 940L, 943I, 947M
CDD
cd00082 (HisKA)

899I

dimer interface
895E, 899I, 903I, 906P, 910I, 913T, 929F, 933S, 936C, 940L, 943I, 947M
CDD
cd00082 (HisKA)

903I

dimer interface
895E, 899I, 903I, 906P, 910I, 913T, 929F, 933S, 936C, 940L, 943I, 947M
CDD
cd00082 (HisKA)

906P

dimer interface
895E, 899I, 903I, 906P, 910I, 913T, 929F, 933S, 936C, 940L, 943I, 947M
CDD
cd00082 (HisKA)

910I

dimer interface
895E, 899I, 903I, 906P, 910I, 913T, 929F, 933S, 936C, 940L, 943I, 947M
CDD
cd00082 (HisKA)

913T

dimer interface
895E, 899I, 903I, 906P, 910I, 913T, 929F, 933S, 936C, 940L, 943I, 947M
CDD
cd00082 (HisKA)

929F

dimer interface
895E, 899I, 903I, 906P, 910I, 913T, 929F, 933S, 936C, 940L, 943I, 947M
CDD
cd00082 (HisKA)

933S

dimer interface
895E, 899I, 903I, 906P, 910I, 913T, 929F, 933S, 936C, 940L, 943I, 947M
CDD
cd00082 (HisKA)

936C

dimer interface
895E, 899I, 903I, 906P, 910I, 913T, 929F, 933S, 936C, 940L, 943I, 947M
CDD
cd00082 (HisKA)

940L

dimer interface
895E, 899I, 903I, 906P, 910I, 913T, 929F, 933S, 936C, 940L, 943I, 947M
CDD
cd00082 (HisKA)

943I

dimer interface
895E, 899I, 903I, 906P, 910I, 913T, 929F, 933S, 936C, 940L, 943I, 947M
CDD
cd00082 (HisKA)

947M

dimer interface
895E, 899I, 903I, 906P, 910I, 913T, 929F, 933S, 936C, 940L, 943I, 947M
CDD
cd00082 (HisKA)
phosphorylation si...

901Q

phosphorylation site
901Q
CDD
cd00082 (HisKA)
ATP binding site c...

1,014D

ATP binding site
1,014D, 1,018N, 1,021R, 1,054V, 1,056H, 1,058G, 1,060G, 1,061L, 1,080G, 1,081L, 1,082G, 1,083L, 1,099Y, 1,101R, 1,105K, 1,106C, 1,108F
CDD
cd16932 (HATPase_Phy-like)

1,018N

ATP binding site
1,014D, 1,018N, 1,021R, 1,054V, 1,056H, 1,058G, 1,060G, 1,061L, 1,080G, 1,081L, 1,082G, 1,083L, 1,099Y, 1,101R, 1,105K, 1,106C, 1,108F
CDD
cd16932 (HATPase_Phy-like)

1,021R

ATP binding site
1,014D, 1,018N, 1,021R, 1,054V, 1,056H, 1,058G, 1,060G, 1,061L, 1,080G, 1,081L, 1,082G, 1,083L, 1,099Y, 1,101R, 1,105K, 1,106C, 1,108F
CDD
cd16932 (HATPase_Phy-like)

1,054V

ATP binding site
1,014D, 1,018N, 1,021R, 1,054V, 1,056H, 1,058G, 1,060G, 1,061L, 1,080G, 1,081L, 1,082G, 1,083L, 1,099Y, 1,101R, 1,105K, 1,106C, 1,108F
CDD
cd16932 (HATPase_Phy-like)

1,056H

ATP binding site
1,014D, 1,018N, 1,021R, 1,054V, 1,056H, 1,058G, 1,060G, 1,061L, 1,080G, 1,081L, 1,082G, 1,083L, 1,099Y, 1,101R, 1,105K, 1,106C, 1,108F
CDD
cd16932 (HATPase_Phy-like)

1,058G

ATP binding site
1,014D, 1,018N, 1,021R, 1,054V, 1,056H, 1,058G, 1,060G, 1,061L, 1,080G, 1,081L, 1,082G, 1,083L, 1,099Y, 1,101R, 1,105K, 1,106C, 1,108F
CDD
cd16932 (HATPase_Phy-like)

1,060G

ATP binding site
1,014D, 1,018N, 1,021R, 1,054V, 1,056H, 1,058G, 1,060G, 1,061L, 1,080G, 1,081L, 1,082G, 1,083L, 1,099Y, 1,101R, 1,105K, 1,106C, 1,108F
CDD
cd16932 (HATPase_Phy-like)

1,061L

ATP binding site
1,014D, 1,018N, 1,021R, 1,054V, 1,056H, 1,058G, 1,060G, 1,061L, 1,080G, 1,081L, 1,082G, 1,083L, 1,099Y, 1,101R, 1,105K, 1,106C, 1,108F
CDD
cd16932 (HATPase_Phy-like)

1,080G

ATP binding site
1,014D, 1,018N, 1,021R, 1,054V, 1,056H, 1,058G, 1,060G, 1,061L, 1,080G, 1,081L, 1,082G, 1,083L, 1,099Y, 1,101R, 1,105K, 1,106C, 1,108F
CDD
cd16932 (HATPase_Phy-like)

1,081L

ATP binding site
1,014D, 1,018N, 1,021R, 1,054V, 1,056H, 1,058G, 1,060G, 1,061L, 1,080G, 1,081L, 1,082G, 1,083L, 1,099Y, 1,101R, 1,105K, 1,106C, 1,108F
CDD
cd16932 (HATPase_Phy-like)

1,082G

ATP binding site
1,014D, 1,018N, 1,021R, 1,054V, 1,056H, 1,058G, 1,060G, 1,061L, 1,080G, 1,081L, 1,082G, 1,083L, 1,099Y, 1,101R, 1,105K, 1,106C, 1,108F
CDD
cd16932 (HATPase_Phy-like)

1,083L

ATP binding site
1,014D, 1,018N, 1,021R, 1,054V, 1,056H, 1,058G, 1,060G, 1,061L, 1,080G, 1,081L, 1,082G, 1,083L, 1,099Y, 1,101R, 1,105K, 1,106C, 1,108F
CDD
cd16932 (HATPase_Phy-like)

1,099Y

ATP binding site
1,014D, 1,018N, 1,021R, 1,054V, 1,056H, 1,058G, 1,060G, 1,061L, 1,080G, 1,081L, 1,082G, 1,083L, 1,099Y, 1,101R, 1,105K, 1,106C, 1,108F
CDD
cd16932 (HATPase_Phy-like)

1,101R

ATP binding site
1,014D, 1,018N, 1,021R, 1,054V, 1,056H, 1,058G, 1,060G, 1,061L, 1,080G, 1,081L, 1,082G, 1,083L, 1,099Y, 1,101R, 1,105K, 1,106C, 1,108F
CDD
cd16932 (HATPase_Phy-like)

1,105K

ATP binding site
1,014D, 1,018N, 1,021R, 1,054V, 1,056H, 1,058G, 1,060G, 1,061L, 1,080G, 1,081L, 1,082G, 1,083L, 1,099Y, 1,101R, 1,105K, 1,106C, 1,108F
CDD
cd16932 (HATPase_Phy-like)

1,106C

ATP binding site
1,014D, 1,018N, 1,021R, 1,054V, 1,056H, 1,058G, 1,060G, 1,061L, 1,080G, 1,081L, 1,082G, 1,083L, 1,099Y, 1,101R, 1,105K, 1,106C, 1,108F
CDD
cd16932 (HATPase_Phy-like)

1,108F

ATP binding site
1,014D, 1,018N, 1,021R, 1,054V, 1,056H, 1,058G, 1,060G, 1,061L, 1,080G, 1,081L, 1,082G, 1,083L, 1,099Y, 1,101R, 1,105K, 1,106C, 1,108F
CDD
cd16932 (HATPase_Phy-like)
ATP-lid cd16932

1,067Q

ATP-lid
1,067Q, 1,083L
CDD
cd16932 (HATPase_Phy-like)

1,083L

ATP-lid
1,067Q, 1,083L
CDD
cd16932 (HATPase_Phy-like)

GO term prediction

Biological Process

GO:0006355 regulation of transcription, DNA-templated
GO:0007165 signal transduction
GO:0009584 detection of visible light
GO:0009585 red, far-red light phototransduction
GO:0017006 protein-tetrapyrrole linkage
GO:0018298 protein-chromophore linkage

Molecular Function

GO:0000155 phosphorelay sensor kinase activity
GO:0005515 protein binding
GO:0009881 photoreceptor activity
GO:0042803 protein homodimerization activity

Cellular Component

None predicted.

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Entry type

Status

Per-residue features