Mp1g03430.1

Protein

Length

495 amino acids

Protein family membership

Exosome complex component RRP45 (IPR033100)

Homologous superfamilies

Homologous superfamily
5 - 295
PNPase/RNase PH domain superfamily (IPR027408)
Homologous superfamily
7 - 220
Ribosomal protein S5 domain 2-type fold (IPR020568)
Homologous superfamily
190 - 293
Exoribonuclease, PH domain 2 superfamily (IPR036345)

1 50 100 150 200 250 300 350 400 450 495

Domains and repeats

Domain
40 - 165
Exoribonuclease, phosphorolytic domain 1 (IPR001247)
194 - 261
Exoribonuclease, phosphorolytic domain 2 (IPR015847)

1 50 100 150 200 250 300 350 400 450 495

Detailed signature matches

IPR027408

PNPase/RNase PH domain superfamily
1. G3DSA:3.30.23... (G...)
  
  5 - 295
  
  GENE3D
  G3DSA:3.30.230.70 (GHMP Kinase)
IPR020568

Ribosomal protein S5 domain 2-type fold
1. SSF54211 (Ribosomal...)
  
  7 - 170
  
  SUPERFAMILY
  SSF54211 (Ribosomal protein S5 domain 2-like)
  
  206 - 220
  
  SUPERFAMILY
  SSF54211 (Ribosomal protein S5 domain 2-like)
IPR036345

Exoribonuclease, PH domain 2 superfamily
1. SSF55666 (Ribonucle...)
  
  190 - 293
  
  SUPERFAMILY
  SSF55666 (Ribonuclease PH domain 2-like)
IPR033100

Exosome complex component RRP45
1. cd11368 (RNase_PH_R...)
  
  8 - 269
  
  CDD
  cd11368 (RNase_PH_RRP45)
IPR001247

Exoribonuclease, phosphorolytic domain 1
1. PF01138 (RNase_PH)
  
  40 - 165
  
  Pfam
  PF01138 (RNase_PH)
IPR015847

Exoribonuclease, phosphorolytic domain 2
1. PF03725 (RNase_PH_C)
  
  194 - 261
  
  Pfam
  PF03725 (RNase_PH_C)

no IPR

Unintegrated signatures

PTHR11097 (EXOSOME ...)

7 - 331

PANTHER
PTHR11097 (EXOSOME COMPLEX EXONUCLEASE RIBOSOMAL RNA PROCESSING PROTEIN)
PTHR11097:SF26 (EXO...)

7 - 331

PANTHER
PTHR11097:SF26 (EXOSOME COMPLEX COMPONENT RRP45A-LIKE)

Other features

mobidb-lite (disord...)

470 - 495

MobiDB Lite
mobidb-lite (disorder_prediction)

334 - 355

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

Rrp40 interface cd...

9S

Rrp40 interface
9S, 10N, 11N, 14E, 15F, 19A, 22A, 24Q
CDD
cd11368 (RNase_PH_RRP45)

10N

Rrp40 interface
9S, 10N, 11N, 14E, 15F, 19A, 22A, 24Q
CDD
cd11368 (RNase_PH_RRP45)

11N

Rrp40 interface
9S, 10N, 11N, 14E, 15F, 19A, 22A, 24Q
CDD
cd11368 (RNase_PH_RRP45)

14E

Rrp40 interface
9S, 10N, 11N, 14E, 15F, 19A, 22A, 24Q
CDD
cd11368 (RNase_PH_RRP45)

15F

Rrp40 interface
9S, 10N, 11N, 14E, 15F, 19A, 22A, 24Q
CDD
cd11368 (RNase_PH_RRP45)

19A

Rrp40 interface
9S, 10N, 11N, 14E, 15F, 19A, 22A, 24Q
CDD
cd11368 (RNase_PH_RRP45)

22A

Rrp40 interface
9S, 10N, 11N, 14E, 15F, 19A, 22A, 24Q
CDD
cd11368 (RNase_PH_RRP45)

24Q

Rrp40 interface
9S, 10N, 11N, 14E, 15F, 19A, 22A, 24Q
CDD
cd11368 (RNase_PH_RRP45)
hexamer interface ...

43K

hexamer interface
43K, 45D, 60V, 62T, 63G, 64T, 79V, 81F, 86P, 103E, 106R, 110R, 132W, 137D, 142D, 160S, 161S, 162Y, 195L, 236V, 237C, 238A, 239I, 240Q, 241K, 242G, 243G, 244G, 245V, 246G, 247V, 252I, 256I
CDD
cd11368 (RNase_PH_RRP45)

45D

hexamer interface
43K, 45D, 60V, 62T, 63G, 64T, 79V, 81F, 86P, 103E, 106R, 110R, 132W, 137D, 142D, 160S, 161S, 162Y, 195L, 236V, 237C, 238A, 239I, 240Q, 241K, 242G, 243G, 244G, 245V, 246G, 247V, 252I, 256I
CDD
cd11368 (RNase_PH_RRP45)

60V

hexamer interface
43K, 45D, 60V, 62T, 63G, 64T, 79V, 81F, 86P, 103E, 106R, 110R, 132W, 137D, 142D, 160S, 161S, 162Y, 195L, 236V, 237C, 238A, 239I, 240Q, 241K, 242G, 243G, 244G, 245V, 246G, 247V, 252I, 256I
CDD
cd11368 (RNase_PH_RRP45)

62T

hexamer interface
43K, 45D, 60V, 62T, 63G, 64T, 79V, 81F, 86P, 103E, 106R, 110R, 132W, 137D, 142D, 160S, 161S, 162Y, 195L, 236V, 237C, 238A, 239I, 240Q, 241K, 242G, 243G, 244G, 245V, 246G, 247V, 252I, 256I
CDD
cd11368 (RNase_PH_RRP45)

63G

hexamer interface
43K, 45D, 60V, 62T, 63G, 64T, 79V, 81F, 86P, 103E, 106R, 110R, 132W, 137D, 142D, 160S, 161S, 162Y, 195L, 236V, 237C, 238A, 239I, 240Q, 241K, 242G, 243G, 244G, 245V, 246G, 247V, 252I, 256I
CDD
cd11368 (RNase_PH_RRP45)

64T

hexamer interface
43K, 45D, 60V, 62T, 63G, 64T, 79V, 81F, 86P, 103E, 106R, 110R, 132W, 137D, 142D, 160S, 161S, 162Y, 195L, 236V, 237C, 238A, 239I, 240Q, 241K, 242G, 243G, 244G, 245V, 246G, 247V, 252I, 256I
CDD
cd11368 (RNase_PH_RRP45)

79V

hexamer interface
43K, 45D, 60V, 62T, 63G, 64T, 79V, 81F, 86P, 103E, 106R, 110R, 132W, 137D, 142D, 160S, 161S, 162Y, 195L, 236V, 237C, 238A, 239I, 240Q, 241K, 242G, 243G, 244G, 245V, 246G, 247V, 252I, 256I
CDD
cd11368 (RNase_PH_RRP45)

81F

hexamer interface
43K, 45D, 60V, 62T, 63G, 64T, 79V, 81F, 86P, 103E, 106R, 110R, 132W, 137D, 142D, 160S, 161S, 162Y, 195L, 236V, 237C, 238A, 239I, 240Q, 241K, 242G, 243G, 244G, 245V, 246G, 247V, 252I, 256I
CDD
cd11368 (RNase_PH_RRP45)

86P

hexamer interface
43K, 45D, 60V, 62T, 63G, 64T, 79V, 81F, 86P, 103E, 106R, 110R, 132W, 137D, 142D, 160S, 161S, 162Y, 195L, 236V, 237C, 238A, 239I, 240Q, 241K, 242G, 243G, 244G, 245V, 246G, 247V, 252I, 256I
CDD
cd11368 (RNase_PH_RRP45)

103E

hexamer interface
43K, 45D, 60V, 62T, 63G, 64T, 79V, 81F, 86P, 103E, 106R, 110R, 132W, 137D, 142D, 160S, 161S, 162Y, 195L, 236V, 237C, 238A, 239I, 240Q, 241K, 242G, 243G, 244G, 245V, 246G, 247V, 252I, 256I
CDD
cd11368 (RNase_PH_RRP45)

106R

hexamer interface
43K, 45D, 60V, 62T, 63G, 64T, 79V, 81F, 86P, 103E, 106R, 110R, 132W, 137D, 142D, 160S, 161S, 162Y, 195L, 236V, 237C, 238A, 239I, 240Q, 241K, 242G, 243G, 244G, 245V, 246G, 247V, 252I, 256I
CDD
cd11368 (RNase_PH_RRP45)

110R

hexamer interface
43K, 45D, 60V, 62T, 63G, 64T, 79V, 81F, 86P, 103E, 106R, 110R, 132W, 137D, 142D, 160S, 161S, 162Y, 195L, 236V, 237C, 238A, 239I, 240Q, 241K, 242G, 243G, 244G, 245V, 246G, 247V, 252I, 256I
CDD
cd11368 (RNase_PH_RRP45)

132W

hexamer interface
43K, 45D, 60V, 62T, 63G, 64T, 79V, 81F, 86P, 103E, 106R, 110R, 132W, 137D, 142D, 160S, 161S, 162Y, 195L, 236V, 237C, 238A, 239I, 240Q, 241K, 242G, 243G, 244G, 245V, 246G, 247V, 252I, 256I
CDD
cd11368 (RNase_PH_RRP45)

137D

hexamer interface
43K, 45D, 60V, 62T, 63G, 64T, 79V, 81F, 86P, 103E, 106R, 110R, 132W, 137D, 142D, 160S, 161S, 162Y, 195L, 236V, 237C, 238A, 239I, 240Q, 241K, 242G, 243G, 244G, 245V, 246G, 247V, 252I, 256I
CDD
cd11368 (RNase_PH_RRP45)

142D

hexamer interface
43K, 45D, 60V, 62T, 63G, 64T, 79V, 81F, 86P, 103E, 106R, 110R, 132W, 137D, 142D, 160S, 161S, 162Y, 195L, 236V, 237C, 238A, 239I, 240Q, 241K, 242G, 243G, 244G, 245V, 246G, 247V, 252I, 256I
CDD
cd11368 (RNase_PH_RRP45)

160S

hexamer interface
43K, 45D, 60V, 62T, 63G, 64T, 79V, 81F, 86P, 103E, 106R, 110R, 132W, 137D, 142D, 160S, 161S, 162Y, 195L, 236V, 237C, 238A, 239I, 240Q, 241K, 242G, 243G, 244G, 245V, 246G, 247V, 252I, 256I
CDD
cd11368 (RNase_PH_RRP45)

161S

hexamer interface
43K, 45D, 60V, 62T, 63G, 64T, 79V, 81F, 86P, 103E, 106R, 110R, 132W, 137D, 142D, 160S, 161S, 162Y, 195L, 236V, 237C, 238A, 239I, 240Q, 241K, 242G, 243G, 244G, 245V, 246G, 247V, 252I, 256I
CDD
cd11368 (RNase_PH_RRP45)

162Y

hexamer interface
43K, 45D, 60V, 62T, 63G, 64T, 79V, 81F, 86P, 103E, 106R, 110R, 132W, 137D, 142D, 160S, 161S, 162Y, 195L, 236V, 237C, 238A, 239I, 240Q, 241K, 242G, 243G, 244G, 245V, 246G, 247V, 252I, 256I
CDD
cd11368 (RNase_PH_RRP45)

195L

hexamer interface
43K, 45D, 60V, 62T, 63G, 64T, 79V, 81F, 86P, 103E, 106R, 110R, 132W, 137D, 142D, 160S, 161S, 162Y, 195L, 236V, 237C, 238A, 239I, 240Q, 241K, 242G, 243G, 244G, 245V, 246G, 247V, 252I, 256I
CDD
cd11368 (RNase_PH_RRP45)

236V

hexamer interface
43K, 45D, 60V, 62T, 63G, 64T, 79V, 81F, 86P, 103E, 106R, 110R, 132W, 137D, 142D, 160S, 161S, 162Y, 195L, 236V, 237C, 238A, 239I, 240Q, 241K, 242G, 243G, 244G, 245V, 246G, 247V, 252I, 256I
CDD
cd11368 (RNase_PH_RRP45)

237C

hexamer interface
43K, 45D, 60V, 62T, 63G, 64T, 79V, 81F, 86P, 103E, 106R, 110R, 132W, 137D, 142D, 160S, 161S, 162Y, 195L, 236V, 237C, 238A, 239I, 240Q, 241K, 242G, 243G, 244G, 245V, 246G, 247V, 252I, 256I
CDD
cd11368 (RNase_PH_RRP45)

238A

hexamer interface
43K, 45D, 60V, 62T, 63G, 64T, 79V, 81F, 86P, 103E, 106R, 110R, 132W, 137D, 142D, 160S, 161S, 162Y, 195L, 236V, 237C, 238A, 239I, 240Q, 241K, 242G, 243G, 244G, 245V, 246G, 247V, 252I, 256I
CDD
cd11368 (RNase_PH_RRP45)

239I

hexamer interface
43K, 45D, 60V, 62T, 63G, 64T, 79V, 81F, 86P, 103E, 106R, 110R, 132W, 137D, 142D, 160S, 161S, 162Y, 195L, 236V, 237C, 238A, 239I, 240Q, 241K, 242G, 243G, 244G, 245V, 246G, 247V, 252I, 256I
CDD
cd11368 (RNase_PH_RRP45)

240Q

hexamer interface
43K, 45D, 60V, 62T, 63G, 64T, 79V, 81F, 86P, 103E, 106R, 110R, 132W, 137D, 142D, 160S, 161S, 162Y, 195L, 236V, 237C, 238A, 239I, 240Q, 241K, 242G, 243G, 244G, 245V, 246G, 247V, 252I, 256I
CDD
cd11368 (RNase_PH_RRP45)

241K

hexamer interface
43K, 45D, 60V, 62T, 63G, 64T, 79V, 81F, 86P, 103E, 106R, 110R, 132W, 137D, 142D, 160S, 161S, 162Y, 195L, 236V, 237C, 238A, 239I, 240Q, 241K, 242G, 243G, 244G, 245V, 246G, 247V, 252I, 256I
CDD
cd11368 (RNase_PH_RRP45)

242G

hexamer interface
43K, 45D, 60V, 62T, 63G, 64T, 79V, 81F, 86P, 103E, 106R, 110R, 132W, 137D, 142D, 160S, 161S, 162Y, 195L, 236V, 237C, 238A, 239I, 240Q, 241K, 242G, 243G, 244G, 245V, 246G, 247V, 252I, 256I
CDD
cd11368 (RNase_PH_RRP45)

243G

hexamer interface
43K, 45D, 60V, 62T, 63G, 64T, 79V, 81F, 86P, 103E, 106R, 110R, 132W, 137D, 142D, 160S, 161S, 162Y, 195L, 236V, 237C, 238A, 239I, 240Q, 241K, 242G, 243G, 244G, 245V, 246G, 247V, 252I, 256I
CDD
cd11368 (RNase_PH_RRP45)

244G

hexamer interface
43K, 45D, 60V, 62T, 63G, 64T, 79V, 81F, 86P, 103E, 106R, 110R, 132W, 137D, 142D, 160S, 161S, 162Y, 195L, 236V, 237C, 238A, 239I, 240Q, 241K, 242G, 243G, 244G, 245V, 246G, 247V, 252I, 256I
CDD
cd11368 (RNase_PH_RRP45)

245V

hexamer interface
43K, 45D, 60V, 62T, 63G, 64T, 79V, 81F, 86P, 103E, 106R, 110R, 132W, 137D, 142D, 160S, 161S, 162Y, 195L, 236V, 237C, 238A, 239I, 240Q, 241K, 242G, 243G, 244G, 245V, 246G, 247V, 252I, 256I
CDD
cd11368 (RNase_PH_RRP45)

246G

hexamer interface
43K, 45D, 60V, 62T, 63G, 64T, 79V, 81F, 86P, 103E, 106R, 110R, 132W, 137D, 142D, 160S, 161S, 162Y, 195L, 236V, 237C, 238A, 239I, 240Q, 241K, 242G, 243G, 244G, 245V, 246G, 247V, 252I, 256I
CDD
cd11368 (RNase_PH_RRP45)

247V

hexamer interface
43K, 45D, 60V, 62T, 63G, 64T, 79V, 81F, 86P, 103E, 106R, 110R, 132W, 137D, 142D, 160S, 161S, 162Y, 195L, 236V, 237C, 238A, 239I, 240Q, 241K, 242G, 243G, 244G, 245V, 246G, 247V, 252I, 256I
CDD
cd11368 (RNase_PH_RRP45)

252I

hexamer interface
43K, 45D, 60V, 62T, 63G, 64T, 79V, 81F, 86P, 103E, 106R, 110R, 132W, 137D, 142D, 160S, 161S, 162Y, 195L, 236V, 237C, 238A, 239I, 240Q, 241K, 242G, 243G, 244G, 245V, 246G, 247V, 252I, 256I
CDD
cd11368 (RNase_PH_RRP45)

256I

hexamer interface
43K, 45D, 60V, 62T, 63G, 64T, 79V, 81F, 86P, 103E, 106R, 110R, 132W, 137D, 142D, 160S, 161S, 162Y, 195L, 236V, 237C, 238A, 239I, 240Q, 241K, 242G, 243G, 244G, 245V, 246G, 247V, 252I, 256I
CDD
cd11368 (RNase_PH_RRP45)

GO term prediction

Biological Process

GO:0006396 RNA processing

Molecular Function

None predicted.

Cellular Component

GO:0000178 exosome (RNase complex)

Filter view on

Entry type

Status

Per-residue features