Mp1g17010.2

Protein

Length

2,320 amino acids

Protein family membership

BRAHMA (BRM) ATPase (IPR031056)

Homologous superfamilies

Homologous superfamily
962 - 1,215
P-loop containing nucleoside triphosphate hydrolase (IPR027417)
1,219 - 1,556
P-loop containing nucleoside triphosphate hydrolase (IPR027417)
1,987 - 2,105
Bromodomain-like superfamily (IPR036427)
Homologous superfamily
975 - 1,224
SNF2-like, N-terminal domain superfamily (IPR038718)

1 500 1000 1500 2000 2320

Domains and repeats

Domain
449 - 485
Glutamine-Leucine-Glutamine, QLQ (IPR014978)
980 - 1,172
Helicase superfamily 1/2, ATP-binding domain (IPR014001)
1,315 - 1,466
Helicase, C-terminal (IPR001650)
1,994 - 2,103
Bromodomain (IPR001487)
Domain
997 - 1,295
SNF2-related domain (IPR000330)

1 500 1000 1500 2000 2320

Detailed signature matches

IPR027417

P-loop containing nucleoside triphosphate hydrolase
1. SSF52540 (P-loop co...)
  
  1,470 - 1,556
  
  SUPERFAMILY
  SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
  
  1,219 - 1,437
  
  SUPERFAMILY
  SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
  
  962 - 1,215
  
  SUPERFAMILY
  SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
IPR038718

SNF2-like, N-terminal domain superfamily
1. G3DSA:3.40.50...
  
  1,187 - 1,224
  
  GENE3D
  G3DSA:3.40.50.10810 (G3DSA:3.40.50.10810)
  
  975 - 1,165
  
  GENE3D
  G3DSA:3.40.50.10810 (G3DSA:3.40.50.10810)
IPR036427

Bromodomain-like superfamily
1. SSF47370 (Bromodomain)
  
  1,987 - 2,105
  
  SUPERFAMILY
  SSF47370 (Bromodomain)
2. G3DSA:1.20.92... (H...)
  
  1,992 - 2,101
  
  GENE3D
  G3DSA:1.20.920.10 (Histone Acetyltransferase; Chain A)
IPR031056

BRAHMA (BRM) ATPase
1. PTHR10799:SF978 (AT...)
  
  249 - 2,228
  
  PANTHER
  PTHR10799:SF978 (ATP-DEPENDENT HELICASE BRM)
IPR014978

Glutamine-Leucine-Glutamine, QLQ
1. PS51666 (QLQ)
  
  450 - 485
  
  PROSITE profiles
  PS51666 (QLQ)
2. SM00951 (QLQ_2)
  
  449 - 485
  
  SMART
  SM00951 (QLQ_2)
IPR014001

Helicase superfamily 1/2, ATP-binding domain
1. PS51192 (HELICASE_A...)
  
  996 - 1,161
  
  PROSITE profiles
  PS51192 (HELICASE_ATP_BIND_1)
2. SM00487 (ultradead3)
  
  980 - 1,172
  
  SMART
  SM00487 (ultradead3)
IPR000330

SNF2-related domain
1. PF00176 (SNF2_N)
  
  997 - 1,295
  
  Pfam
  PF00176 (SNF2_N)
IPR001650

Helicase, C-terminal
1. PS51194 (HELICASE_CTER)
  
  1,317 - 1,466
  
  PROSITE profiles
  PS51194 (HELICASE_CTER)
2. SM00490 (helicmild6)
  
  1,343 - 1,427
  
  SMART
  SM00490 (helicmild6)
3. PF00271 (Helicase_C)
  
  1,315 - 1,427
  
  Pfam
  PF00271 (Helicase_C)
IPR001487

Bromodomain
1. PR00503 (BROMODOMAIN)
  
  2,066 - 2,085
  
  PRINTS
  PR00503 (BROMODOMAIN)
  
  2,032 - 2,048
  
  PRINTS
  PR00503 (BROMODOMAIN)
  
  2,048 - 2,066
  
  PRINTS
  PR00503 (BROMODOMAIN)
2. SM00297 (bromo_6)
  
  1,994 - 2,103
  
  SMART
  SM00297 (bromo_6)
3. PS50014 (BROMODOMAIN_2)
  
  2,015 - 2,078
  
  PROSITE profiles
  PS50014 (BROMODOMAIN_2)
4. PF00439 (Bromodomain)
  
  2,019 - 2,080
  
  Pfam
  PF00439 (Bromodomain)

no IPR

Unintegrated signatures

G3DSA:3.40.50...

1,225 - 1,254

GENE3D
G3DSA:3.40.50.300 (G3DSA:3.40.50.300)

1,278 - 1,436

GENE3D
G3DSA:3.40.50.300 (G3DSA:3.40.50.300)
PTHR10799 (SNF2/RAD...)

249 - 2,228

PANTHER
PTHR10799 (SNF2/RAD54 HELICASE FAMILY)
cd04369 (Bromodomain)

1,997 - 2,094

CDD
cd04369 (Bromodomain)
cd18793 (SF2_C_SNF)

1,311 - 1,437

CDD
cd18793 (SF2_C_SNF)

Other features

Coil

325 - 345

COILS
Coil (Coil)

279 - 299

COILS
Coil (Coil)

362 - 409

COILS
Coil (Coil)

735 - 755

COILS
Coil (Coil)
mobidb-lite (disord...)

249 - 290

MobiDB Lite
mobidb-lite (disorder_prediction)

2,113 - 2,208

MobiDB Lite
mobidb-lite (disorder_prediction)

1 - 59

MobiDB Lite
mobidb-lite (disorder_prediction)

1,620 - 1,684

MobiDB Lite
mobidb-lite (disorder_prediction)

406 - 447

MobiDB Lite
mobidb-lite (disorder_prediction)

1,730 - 1,846

MobiDB Lite
mobidb-lite (disorder_prediction)

1,702 - 1,721

MobiDB Lite
mobidb-lite (disorder_prediction)

521 - 595

MobiDB Lite
mobidb-lite (disorder_prediction)

2,223 - 2,320

MobiDB Lite
mobidb-lite (disorder_prediction)
mobidb-lite (Polyam...)

2,172 - 2,208

MobiDB Lite
mobidb-lite (disorder_prediction)
Feature: Polyampholyte

1,730 - 1,768

MobiDB Lite
mobidb-lite (disorder_prediction)
Feature: Polyampholyte

1,812 - 1,831

MobiDB Lite
mobidb-lite (disorder_prediction)
Feature: Polyampholyte
mobidb-lite (Polar)

2,142 - 2,158

MobiDB Lite
mobidb-lite (disorder_prediction)
Feature: Polar

2,252 - 2,278

MobiDB Lite
mobidb-lite (disorder_prediction)
Feature: Polar

549 - 573

MobiDB Lite
mobidb-lite (disorder_prediction)
Feature: Polar

15 - 59

MobiDB Lite
mobidb-lite (disorder_prediction)
Feature: Polar

257 - 290

MobiDB Lite
mobidb-lite (disorder_prediction)
Feature: Polar

Residue annotation

DNA binding site c...

1,338M

DNA binding site
1,338M, 1,339T, 1,347E, 1,390R, 1,411P, 1,412N
CDD
cd18793 (SF2_C_SNF)

1,339T

DNA binding site
1,338M, 1,339T, 1,347E, 1,390R, 1,411P, 1,412N
CDD
cd18793 (SF2_C_SNF)

1,347E

DNA binding site
1,338M, 1,339T, 1,347E, 1,390R, 1,411P, 1,412N
CDD
cd18793 (SF2_C_SNF)

1,390R

DNA binding site
1,338M, 1,339T, 1,347E, 1,390R, 1,411P, 1,412N
CDD
cd18793 (SF2_C_SNF)

1,411P

DNA binding site
1,338M, 1,339T, 1,347E, 1,390R, 1,411P, 1,412N
CDD
cd18793 (SF2_C_SNF)

1,412N

DNA binding site
1,338M, 1,339T, 1,347E, 1,390R, 1,411P, 1,412N
CDD
cd18793 (SF2_C_SNF)
ATP binding site c...

1,396L

ATP binding site
1,396L, 1,397N, 1,399Q, 1,422R, 1,425R
CDD
cd18793 (SF2_C_SNF)

1,397N

ATP binding site
1,396L, 1,397N, 1,399Q, 1,422R, 1,425R
CDD
cd18793 (SF2_C_SNF)

1,399Q

ATP binding site
1,396L, 1,397N, 1,399Q, 1,422R, 1,425R
CDD
cd18793 (SF2_C_SNF)

1,422R

ATP binding site
1,396L, 1,397N, 1,399Q, 1,422R, 1,425R
CDD
cd18793 (SF2_C_SNF)

1,425R

ATP binding site
1,396L, 1,397N, 1,399Q, 1,422R, 1,425R
CDD
cd18793 (SF2_C_SNF)
acetyllysine bindi...

2,027P

acetyllysine binding site
2,027P, 2,032C, 2,035Y, 2,074V, 2,078N, 2,083V
CDD
cd04369 (Bromodomain)

2,032C

acetyllysine binding site
2,027P, 2,032C, 2,035Y, 2,074V, 2,078N, 2,083V
CDD
cd04369 (Bromodomain)

2,035Y

acetyllysine binding site
2,027P, 2,032C, 2,035Y, 2,074V, 2,078N, 2,083V
CDD
cd04369 (Bromodomain)

2,074V

acetyllysine binding site
2,027P, 2,032C, 2,035Y, 2,074V, 2,078N, 2,083V
CDD
cd04369 (Bromodomain)

2,078N

acetyllysine binding site
2,027P, 2,032C, 2,035Y, 2,074V, 2,078N, 2,083V
CDD
cd04369 (Bromodomain)

2,083V

acetyllysine binding site
2,027P, 2,032C, 2,035Y, 2,074V, 2,078N, 2,083V
CDD
cd04369 (Bromodomain)

GO term prediction

Biological Process

GO:0006355 regulation of transcription, DNA-templated
GO:0040029 regulation of gene expression, epigenetic
GO:0043044 ATP-dependent chromatin remodeling

Molecular Function

GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008094 DNA-dependent ATPase activity
GO:0070615 nucleosome-dependent ATPase activity

Cellular Component

GO:0005634 nucleus

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Entry type

Status

Per-residue features