Mp2g10560.1

Protein

Length

768 amino acids

Protein family membership

Glutamyl/glutaminyl-tRNA synthetase (IPR000924)
- Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic (IPR004526)

Homologous superfamilies

Homologous superfamily
54 - 157
Glutathione S-transferase, C-terminal domain superfamily (IPR036282)
186 - 522
Rossmann-like alpha/beta/alpha sandwich fold (IPR014729)
523 - 707
Ribosomal protein L25/Gln-tRNA synthetase, N-terminal (IPR020056)
Homologous superfamily
520 - 717
Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily (IPR011035)

1 100 200 300 400 500 600 700 768

Domains and repeats

Domain
96 - 157
Glutathione S-transferase, C-terminal (IPR004046)
213 - 517
Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain (IPR020058)
520 - 697
Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain (IPR020059)

1 100 200 300 400 500 600 700 768

Detailed signature matches

IPR036282

Glutathione S-transferase, C-terminal domain superfamily
1. SSF47616 (GST C-ter...)
  
  54 - 157
  
  SUPERFAMILY
  SSF47616 (GST C-terminal domain-like)
IPR014729

Rossmann-like alpha/beta/alpha sandwich fold
1. G3DSA:3.40.50... (HUPs)
  
  186 - 522
  
  GENE3D
  G3DSA:3.40.50.620 (HUPs)
IPR011035

Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily
1. SSF50715 (Ribosomal...)
  
  520 - 717
  
  SUPERFAMILY
  SSF50715 (Ribosomal protein L25-like)
IPR020056

Ribosomal protein L25/Gln-tRNA synthetase, N-terminal
1. G3DSA:2.40.24... (R...)
  
  523 - 527
  
  GENE3D
  G3DSA:2.40.240.10 (Ribosomal Protein L25; Chain P)
  
  635 - 707
  
  GENE3D
  G3DSA:2.40.240.10 (Ribosomal Protein L25; Chain P)
  
  528 - 634
  
  GENE3D
  G3DSA:2.40.240.10 (Ribosomal Protein L25; Chain P)
IPR000924

Glutamyl/glutaminyl-tRNA synthetase
1. PR00987 (TRNASYNTHGLU)
  
  217 - 229
  
  PRINTS
  PR00987 (TRNASYNTHGLU)
  
  407 - 415
  
  PRINTS
  PR00987 (TRNASYNTHGLU)
  
  391 - 401
  
  PRINTS
  PR00987 (TRNASYNTHGLU)
  
  231 - 242
  
  PRINTS
  PR00987 (TRNASYNTHGLU)
  
  246 - 259
  
  PRINTS
  PR00987 (TRNASYNTHGLU)
IPR004526

Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic
1. TIGR00463
  
  188 - 696
  
  TIGRFAMs
  TIGR00463 (TIGR00463)
2. MF_02076 (Glu_tRNA_...)
  
  11 - 709
  
  HAMAP
  MF_02076 (Glu_tRNA_synth_type2)
IPR004046

Glutathione S-transferase, C-terminal
1. PF14497 (GST_C_3)
  
  96 - 157
  
  Pfam
  PF14497 (GST_C_3)
IPR020058

Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain
1. PF00749 (tRNA-synt_1c)
  
  213 - 517
  
  Pfam
  PF00749 (tRNA-synt_1c)
IPR020059

Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain
1. PF03950 (tRNA-synt_...)
  
  520 - 697
  
  Pfam
  PF03950 (tRNA-synt_1c_C)
IPR001412

Aminoacyl-tRNA synthetase, class I, conserved site
1. PS00178 (AA_TRNA_LI...)
  
  220 - 231
  
  PROSITE patterns
  PS00178 (AA_TRNA_LIGASE_I)

no IPR

Unintegrated signatures

G3DSA:1.20.10...

2 - 168

GENE3D
G3DSA:1.20.1050.130 (G3DSA:1.20.1050.130)
PTHR43097 (GLUTAMIN...)

1 - 720

PANTHER
PTHR43097 (GLUTAMINE-TRNA LIGASE)
PTHR43097:SF12 (OS0...)

1 - 720

PANTHER
PTHR43097:SF12 (OS01G0271200 PROTEIN)
SSF52374 (Nucleotid...)

213 - 526

SUPERFAMILY
SSF52374 (Nucleotidylyl transferase)
cd00807 (GlnRS_core)

213 - 522

CDD
cd00807 (GlnRS_core)
cd10289 (GST_C_AaRS...)

75 - 156

CDD
cd10289 (GST_C_AaRS_like)

Residue annotation

protein interface ...

76T

protein interface 1
76T, 77A, 78Q, 80D, 81E, 82W, 83I, 84D, 85Y, 87P, 88I, 98A, 101Y, 107E, 108L
CDD
cd10289 (GST_C_AaRS_like)

77A

protein interface 1
76T, 77A, 78Q, 80D, 81E, 82W, 83I, 84D, 85Y, 87P, 88I, 98A, 101Y, 107E, 108L
CDD
cd10289 (GST_C_AaRS_like)

78Q

protein interface 1
76T, 77A, 78Q, 80D, 81E, 82W, 83I, 84D, 85Y, 87P, 88I, 98A, 101Y, 107E, 108L
CDD
cd10289 (GST_C_AaRS_like)

80D

protein interface 1
76T, 77A, 78Q, 80D, 81E, 82W, 83I, 84D, 85Y, 87P, 88I, 98A, 101Y, 107E, 108L
CDD
cd10289 (GST_C_AaRS_like)

81E

protein interface 1
76T, 77A, 78Q, 80D, 81E, 82W, 83I, 84D, 85Y, 87P, 88I, 98A, 101Y, 107E, 108L
CDD
cd10289 (GST_C_AaRS_like)

82W

protein interface 1
76T, 77A, 78Q, 80D, 81E, 82W, 83I, 84D, 85Y, 87P, 88I, 98A, 101Y, 107E, 108L
CDD
cd10289 (GST_C_AaRS_like)

83I

protein interface 1
76T, 77A, 78Q, 80D, 81E, 82W, 83I, 84D, 85Y, 87P, 88I, 98A, 101Y, 107E, 108L
CDD
cd10289 (GST_C_AaRS_like)

84D

protein interface 1
76T, 77A, 78Q, 80D, 81E, 82W, 83I, 84D, 85Y, 87P, 88I, 98A, 101Y, 107E, 108L
CDD
cd10289 (GST_C_AaRS_like)

85Y

protein interface 1
76T, 77A, 78Q, 80D, 81E, 82W, 83I, 84D, 85Y, 87P, 88I, 98A, 101Y, 107E, 108L
CDD
cd10289 (GST_C_AaRS_like)

87P

protein interface 1
76T, 77A, 78Q, 80D, 81E, 82W, 83I, 84D, 85Y, 87P, 88I, 98A, 101Y, 107E, 108L
CDD
cd10289 (GST_C_AaRS_like)

88I

protein interface 1
76T, 77A, 78Q, 80D, 81E, 82W, 83I, 84D, 85Y, 87P, 88I, 98A, 101Y, 107E, 108L
CDD
cd10289 (GST_C_AaRS_like)

98A

protein interface 1
76T, 77A, 78Q, 80D, 81E, 82W, 83I, 84D, 85Y, 87P, 88I, 98A, 101Y, 107E, 108L
CDD
cd10289 (GST_C_AaRS_like)

101Y

protein interface 1
76T, 77A, 78Q, 80D, 81E, 82W, 83I, 84D, 85Y, 87P, 88I, 98A, 101Y, 107E, 108L
CDD
cd10289 (GST_C_AaRS_like)

107E

protein interface 1
76T, 77A, 78Q, 80D, 81E, 82W, 83I, 84D, 85Y, 87P, 88I, 98A, 101Y, 107E, 108L
CDD
cd10289 (GST_C_AaRS_like)

108L

protein interface 1
76T, 77A, 78Q, 80D, 81E, 82W, 83I, 84D, 85Y, 87P, 88I, 98A, 101Y, 107E, 108L
CDD
cd10289 (GST_C_AaRS_like)
protein interface ...

106L

protein interface 2
106L, 107E, 108L, 109R, 110T, 145P, 146H, 148A, 149R, 153S, 156N
CDD
cd10289 (GST_C_AaRS_like)

107E

protein interface 2
106L, 107E, 108L, 109R, 110T, 145P, 146H, 148A, 149R, 153S, 156N
CDD
cd10289 (GST_C_AaRS_like)

108L

protein interface 2
106L, 107E, 108L, 109R, 110T, 145P, 146H, 148A, 149R, 153S, 156N
CDD
cd10289 (GST_C_AaRS_like)

109R

protein interface 2
106L, 107E, 108L, 109R, 110T, 145P, 146H, 148A, 149R, 153S, 156N
CDD
cd10289 (GST_C_AaRS_like)

110T

protein interface 2
106L, 107E, 108L, 109R, 110T, 145P, 146H, 148A, 149R, 153S, 156N
CDD
cd10289 (GST_C_AaRS_like)

145P

protein interface 2
106L, 107E, 108L, 109R, 110T, 145P, 146H, 148A, 149R, 153S, 156N
CDD
cd10289 (GST_C_AaRS_like)

146H

protein interface 2
106L, 107E, 108L, 109R, 110T, 145P, 146H, 148A, 149R, 153S, 156N
CDD
cd10289 (GST_C_AaRS_like)

148A

protein interface 2
106L, 107E, 108L, 109R, 110T, 145P, 146H, 148A, 149R, 153S, 156N
CDD
cd10289 (GST_C_AaRS_like)

149R

protein interface 2
106L, 107E, 108L, 109R, 110T, 145P, 146H, 148A, 149R, 153S, 156N
CDD
cd10289 (GST_C_AaRS_like)

153S

protein interface 2
106L, 107E, 108L, 109R, 110T, 145P, 146H, 148A, 149R, 153S, 156N
CDD
cd10289 (GST_C_AaRS_like)

156N

protein interface 2
106L, 107E, 108L, 109R, 110T, 145P, 146H, 148A, 149R, 153S, 156N
CDD
cd10289 (GST_C_AaRS_like)
active site cd00807

217R

active site
217R, 218F, 219P, 220P, 221E, 227H, 229G, 230H, 232K, 233A, 253D, 255T, 256N, 393Y, 397C, 410L, 411R, 412S, 415Y, 418R, 436V, 441R, 442L, 451K
CDD
cd00807 (GlnRS_core)

218F

active site
217R, 218F, 219P, 220P, 221E, 227H, 229G, 230H, 232K, 233A, 253D, 255T, 256N, 393Y, 397C, 410L, 411R, 412S, 415Y, 418R, 436V, 441R, 442L, 451K
CDD
cd00807 (GlnRS_core)

219P

active site
217R, 218F, 219P, 220P, 221E, 227H, 229G, 230H, 232K, 233A, 253D, 255T, 256N, 393Y, 397C, 410L, 411R, 412S, 415Y, 418R, 436V, 441R, 442L, 451K
CDD
cd00807 (GlnRS_core)

220P

active site
217R, 218F, 219P, 220P, 221E, 227H, 229G, 230H, 232K, 233A, 253D, 255T, 256N, 393Y, 397C, 410L, 411R, 412S, 415Y, 418R, 436V, 441R, 442L, 451K
CDD
cd00807 (GlnRS_core)

221E

active site
217R, 218F, 219P, 220P, 221E, 227H, 229G, 230H, 232K, 233A, 253D, 255T, 256N, 393Y, 397C, 410L, 411R, 412S, 415Y, 418R, 436V, 441R, 442L, 451K
CDD
cd00807 (GlnRS_core)

227H

active site
217R, 218F, 219P, 220P, 221E, 227H, 229G, 230H, 232K, 233A, 253D, 255T, 256N, 393Y, 397C, 410L, 411R, 412S, 415Y, 418R, 436V, 441R, 442L, 451K
CDD
cd00807 (GlnRS_core)

229G

active site
217R, 218F, 219P, 220P, 221E, 227H, 229G, 230H, 232K, 233A, 253D, 255T, 256N, 393Y, 397C, 410L, 411R, 412S, 415Y, 418R, 436V, 441R, 442L, 451K
CDD
cd00807 (GlnRS_core)

230H

active site
217R, 218F, 219P, 220P, 221E, 227H, 229G, 230H, 232K, 233A, 253D, 255T, 256N, 393Y, 397C, 410L, 411R, 412S, 415Y, 418R, 436V, 441R, 442L, 451K
CDD
cd00807 (GlnRS_core)

232K

active site
217R, 218F, 219P, 220P, 221E, 227H, 229G, 230H, 232K, 233A, 253D, 255T, 256N, 393Y, 397C, 410L, 411R, 412S, 415Y, 418R, 436V, 441R, 442L, 451K
CDD
cd00807 (GlnRS_core)

233A

active site
217R, 218F, 219P, 220P, 221E, 227H, 229G, 230H, 232K, 233A, 253D, 255T, 256N, 393Y, 397C, 410L, 411R, 412S, 415Y, 418R, 436V, 441R, 442L, 451K
CDD
cd00807 (GlnRS_core)

253D

active site
217R, 218F, 219P, 220P, 221E, 227H, 229G, 230H, 232K, 233A, 253D, 255T, 256N, 393Y, 397C, 410L, 411R, 412S, 415Y, 418R, 436V, 441R, 442L, 451K
CDD
cd00807 (GlnRS_core)

255T

active site
217R, 218F, 219P, 220P, 221E, 227H, 229G, 230H, 232K, 233A, 253D, 255T, 256N, 393Y, 397C, 410L, 411R, 412S, 415Y, 418R, 436V, 441R, 442L, 451K
CDD
cd00807 (GlnRS_core)

256N

active site
217R, 218F, 219P, 220P, 221E, 227H, 229G, 230H, 232K, 233A, 253D, 255T, 256N, 393Y, 397C, 410L, 411R, 412S, 415Y, 418R, 436V, 441R, 442L, 451K
CDD
cd00807 (GlnRS_core)

393Y

active site
217R, 218F, 219P, 220P, 221E, 227H, 229G, 230H, 232K, 233A, 253D, 255T, 256N, 393Y, 397C, 410L, 411R, 412S, 415Y, 418R, 436V, 441R, 442L, 451K
CDD
cd00807 (GlnRS_core)

397C

active site
217R, 218F, 219P, 220P, 221E, 227H, 229G, 230H, 232K, 233A, 253D, 255T, 256N, 393Y, 397C, 410L, 411R, 412S, 415Y, 418R, 436V, 441R, 442L, 451K
CDD
cd00807 (GlnRS_core)

410L

active site
217R, 218F, 219P, 220P, 221E, 227H, 229G, 230H, 232K, 233A, 253D, 255T, 256N, 393Y, 397C, 410L, 411R, 412S, 415Y, 418R, 436V, 441R, 442L, 451K
CDD
cd00807 (GlnRS_core)

411R

active site
217R, 218F, 219P, 220P, 221E, 227H, 229G, 230H, 232K, 233A, 253D, 255T, 256N, 393Y, 397C, 410L, 411R, 412S, 415Y, 418R, 436V, 441R, 442L, 451K
CDD
cd00807 (GlnRS_core)

412S

active site
217R, 218F, 219P, 220P, 221E, 227H, 229G, 230H, 232K, 233A, 253D, 255T, 256N, 393Y, 397C, 410L, 411R, 412S, 415Y, 418R, 436V, 441R, 442L, 451K
CDD
cd00807 (GlnRS_core)

415Y

active site
217R, 218F, 219P, 220P, 221E, 227H, 229G, 230H, 232K, 233A, 253D, 255T, 256N, 393Y, 397C, 410L, 411R, 412S, 415Y, 418R, 436V, 441R, 442L, 451K
CDD
cd00807 (GlnRS_core)

418R

active site
217R, 218F, 219P, 220P, 221E, 227H, 229G, 230H, 232K, 233A, 253D, 255T, 256N, 393Y, 397C, 410L, 411R, 412S, 415Y, 418R, 436V, 441R, 442L, 451K
CDD
cd00807 (GlnRS_core)

436V

active site
217R, 218F, 219P, 220P, 221E, 227H, 229G, 230H, 232K, 233A, 253D, 255T, 256N, 393Y, 397C, 410L, 411R, 412S, 415Y, 418R, 436V, 441R, 442L, 451K
CDD
cd00807 (GlnRS_core)

441R

active site
217R, 218F, 219P, 220P, 221E, 227H, 229G, 230H, 232K, 233A, 253D, 255T, 256N, 393Y, 397C, 410L, 411R, 412S, 415Y, 418R, 436V, 441R, 442L, 451K
CDD
cd00807 (GlnRS_core)

442L

active site
217R, 218F, 219P, 220P, 221E, 227H, 229G, 230H, 232K, 233A, 253D, 255T, 256N, 393Y, 397C, 410L, 411R, 412S, 415Y, 418R, 436V, 441R, 442L, 451K
CDD
cd00807 (GlnRS_core)

451K

active site
217R, 218F, 219P, 220P, 221E, 227H, 229G, 230H, 232K, 233A, 253D, 255T, 256N, 393Y, 397C, 410L, 411R, 412S, 415Y, 418R, 436V, 441R, 442L, 451K
CDD
cd00807 (GlnRS_core)
HIGH motif cd00807

227H

HIGH motif
227H, 228I, 229G, 230H
CDD
cd00807 (GlnRS_core)

228I

HIGH motif
227H, 228I, 229G, 230H
CDD
cd00807 (GlnRS_core)

229G

HIGH motif
227H, 228I, 229G, 230H
CDD
cd00807 (GlnRS_core)

230H

HIGH motif
227H, 228I, 229G, 230H
CDD
cd00807 (GlnRS_core)
KMSKS motif cd00807

448L

KMSKS motif
448L, 449L, 450S, 451K, 452R
CDD
cd00807 (GlnRS_core)

449L

KMSKS motif
448L, 449L, 450S, 451K, 452R
CDD
cd00807 (GlnRS_core)

450S

KMSKS motif
448L, 449L, 450S, 451K, 452R
CDD
cd00807 (GlnRS_core)

451K

KMSKS motif
448L, 449L, 450S, 451K, 452R
CDD
cd00807 (GlnRS_core)

452R

KMSKS motif
448L, 449L, 450S, 451K, 452R
CDD
cd00807 (GlnRS_core)

GO term prediction

Biological Process

GO:0006412 translation
GO:0006418 tRNA aminoacylation for protein translation
GO:0006424 glutamyl-tRNA aminoacylation
GO:0043039 tRNA aminoacylation

Molecular Function

GO:0000166 nucleotide binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004818 glutamate-tRNA ligase activity
GO:0005524 ATP binding

Cellular Component

GO:0005737 cytoplasm

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Entry type

Status

Per-residue features