Mp1g11030.1

Protein

Length

416 amino acids

Protein family membership

Polyketide synthase, type III (IPR011141)

Homologous superfamilies

Homologous superfamily
24 - 257
Thiolase-like (IPR016039)
257 - 416
Thiolase-like (IPR016039)

1 50 100 150 200 250 300 350 416

Domains and repeats

Domain
32 - 250
Chalcone/stilbene synthase, N-terminal (IPR001099)
260 - 414
Chalcone/stilbene synthase, C-terminal (IPR012328)

1 50 100 150 200 250 300 350 416

Detailed signature matches

IPR016039

Thiolase-like
1. SSF53901 (Thiolase-...)
  
  34 - 254
  
  SUPERFAMILY
  SSF53901 (Thiolase-like)
  
  257 - 413
  
  SUPERFAMILY
  SSF53901 (Thiolase-like)
2. G3DSA:3.40.47.10
  
  258 - 416
  
  GENE3D
  G3DSA:3.40.47.10 (G3DSA:3.40.47.10)
  
  24 - 257
  
  GENE3D
  G3DSA:3.40.47.10 (G3DSA:3.40.47.10)
IPR011141

Polyketide synthase, type III
1. PTHR11877 (HYDROXYM...)
  
  32 - 415
  
  PANTHER
  PTHR11877 (HYDROXYMETHYLGLUTARYL-COA SYNTHASE)
2. PIRSF000451 (PKS_III)
  
  26 - 416
  
  PIRSF
  PIRSF000451 (PKS_III)
IPR001099

Chalcone/stilbene synthase, N-terminal
1. PF00195 (Chal_sti_s...)
  
  32 - 250
  
  Pfam
  PF00195 (Chal_sti_synt_N)
IPR012328

Chalcone/stilbene synthase, C-terminal
1. PF02797 (Chal_sti_s...)
  
  260 - 414
  
  Pfam
  PF02797 (Chal_sti_synt_C)

no IPR

Unintegrated signatures

PTHR11877:SF10 (TYP...)

32 - 415

PANTHER
PTHR11877:SF10 (TYPE III POLYKETIDE SYNTHASE B)
cd00831 (CHS_like)

39 - 411

CDD
cd00831 (CHS_like)

Residue annotation

malonyl-CoA bindin...

77K

malonyl-CoA binding site
77K, 80R, 81L, 237F, 287F, 329G, 330P, 331A
CDD
cd00831 (CHS_like)

80R

malonyl-CoA binding site
77K, 80R, 81L, 237F, 287F, 329G, 330P, 331A
CDD
cd00831 (CHS_like)

81L

malonyl-CoA binding site
77K, 80R, 81L, 237F, 287F, 329G, 330P, 331A
CDD
cd00831 (CHS_like)

237F

malonyl-CoA binding site
77K, 80R, 81L, 237F, 287F, 329G, 330P, 331A
CDD
cd00831 (CHS_like)

287F

malonyl-CoA binding site
77K, 80R, 81L, 237F, 287F, 329G, 330P, 331A
CDD
cd00831 (CHS_like)

329G

malonyl-CoA binding site
77K, 80R, 81L, 237F, 287F, 329G, 330P, 331A
CDD
cd00831 (CHS_like)

330P

malonyl-CoA binding site
77K, 80R, 81L, 237F, 287F, 329G, 330P, 331A
CDD
cd00831 (CHS_like)

331A

malonyl-CoA binding site
77K, 80R, 81L, 237F, 287F, 329G, 330P, 331A
CDD
cd00831 (CHS_like)
dimer interface cd...

113V

dimer interface
113V, 114K, 117L, 158R, 159L, 164L, 168I, 174N, 175D, 176V, 177N, 178R, 179V, 180M, 184L, 185G, 194R, 195V, 198D, 201E, 202N, 203N, 264A, 266Q, 267S, 268F, 278G, 279T, 280L, 281T, 406T
CDD
cd00831 (CHS_like)

114K

dimer interface
113V, 114K, 117L, 158R, 159L, 164L, 168I, 174N, 175D, 176V, 177N, 178R, 179V, 180M, 184L, 185G, 194R, 195V, 198D, 201E, 202N, 203N, 264A, 266Q, 267S, 268F, 278G, 279T, 280L, 281T, 406T
CDD
cd00831 (CHS_like)

117L

dimer interface
113V, 114K, 117L, 158R, 159L, 164L, 168I, 174N, 175D, 176V, 177N, 178R, 179V, 180M, 184L, 185G, 194R, 195V, 198D, 201E, 202N, 203N, 264A, 266Q, 267S, 268F, 278G, 279T, 280L, 281T, 406T
CDD
cd00831 (CHS_like)

158R

dimer interface
113V, 114K, 117L, 158R, 159L, 164L, 168I, 174N, 175D, 176V, 177N, 178R, 179V, 180M, 184L, 185G, 194R, 195V, 198D, 201E, 202N, 203N, 264A, 266Q, 267S, 268F, 278G, 279T, 280L, 281T, 406T
CDD
cd00831 (CHS_like)

159L

dimer interface
113V, 114K, 117L, 158R, 159L, 164L, 168I, 174N, 175D, 176V, 177N, 178R, 179V, 180M, 184L, 185G, 194R, 195V, 198D, 201E, 202N, 203N, 264A, 266Q, 267S, 268F, 278G, 279T, 280L, 281T, 406T
CDD
cd00831 (CHS_like)

164L

dimer interface
113V, 114K, 117L, 158R, 159L, 164L, 168I, 174N, 175D, 176V, 177N, 178R, 179V, 180M, 184L, 185G, 194R, 195V, 198D, 201E, 202N, 203N, 264A, 266Q, 267S, 268F, 278G, 279T, 280L, 281T, 406T
CDD
cd00831 (CHS_like)

168I

dimer interface
113V, 114K, 117L, 158R, 159L, 164L, 168I, 174N, 175D, 176V, 177N, 178R, 179V, 180M, 184L, 185G, 194R, 195V, 198D, 201E, 202N, 203N, 264A, 266Q, 267S, 268F, 278G, 279T, 280L, 281T, 406T
CDD
cd00831 (CHS_like)

174N

dimer interface
113V, 114K, 117L, 158R, 159L, 164L, 168I, 174N, 175D, 176V, 177N, 178R, 179V, 180M, 184L, 185G, 194R, 195V, 198D, 201E, 202N, 203N, 264A, 266Q, 267S, 268F, 278G, 279T, 280L, 281T, 406T
CDD
cd00831 (CHS_like)

175D

dimer interface
113V, 114K, 117L, 158R, 159L, 164L, 168I, 174N, 175D, 176V, 177N, 178R, 179V, 180M, 184L, 185G, 194R, 195V, 198D, 201E, 202N, 203N, 264A, 266Q, 267S, 268F, 278G, 279T, 280L, 281T, 406T
CDD
cd00831 (CHS_like)

176V

dimer interface
113V, 114K, 117L, 158R, 159L, 164L, 168I, 174N, 175D, 176V, 177N, 178R, 179V, 180M, 184L, 185G, 194R, 195V, 198D, 201E, 202N, 203N, 264A, 266Q, 267S, 268F, 278G, 279T, 280L, 281T, 406T
CDD
cd00831 (CHS_like)

177N

dimer interface
113V, 114K, 117L, 158R, 159L, 164L, 168I, 174N, 175D, 176V, 177N, 178R, 179V, 180M, 184L, 185G, 194R, 195V, 198D, 201E, 202N, 203N, 264A, 266Q, 267S, 268F, 278G, 279T, 280L, 281T, 406T
CDD
cd00831 (CHS_like)

178R

dimer interface
113V, 114K, 117L, 158R, 159L, 164L, 168I, 174N, 175D, 176V, 177N, 178R, 179V, 180M, 184L, 185G, 194R, 195V, 198D, 201E, 202N, 203N, 264A, 266Q, 267S, 268F, 278G, 279T, 280L, 281T, 406T
CDD
cd00831 (CHS_like)

179V

dimer interface
113V, 114K, 117L, 158R, 159L, 164L, 168I, 174N, 175D, 176V, 177N, 178R, 179V, 180M, 184L, 185G, 194R, 195V, 198D, 201E, 202N, 203N, 264A, 266Q, 267S, 268F, 278G, 279T, 280L, 281T, 406T
CDD
cd00831 (CHS_like)

180M

dimer interface
113V, 114K, 117L, 158R, 159L, 164L, 168I, 174N, 175D, 176V, 177N, 178R, 179V, 180M, 184L, 185G, 194R, 195V, 198D, 201E, 202N, 203N, 264A, 266Q, 267S, 268F, 278G, 279T, 280L, 281T, 406T
CDD
cd00831 (CHS_like)

184L

dimer interface
113V, 114K, 117L, 158R, 159L, 164L, 168I, 174N, 175D, 176V, 177N, 178R, 179V, 180M, 184L, 185G, 194R, 195V, 198D, 201E, 202N, 203N, 264A, 266Q, 267S, 268F, 278G, 279T, 280L, 281T, 406T
CDD
cd00831 (CHS_like)

185G

dimer interface
113V, 114K, 117L, 158R, 159L, 164L, 168I, 174N, 175D, 176V, 177N, 178R, 179V, 180M, 184L, 185G, 194R, 195V, 198D, 201E, 202N, 203N, 264A, 266Q, 267S, 268F, 278G, 279T, 280L, 281T, 406T
CDD
cd00831 (CHS_like)

194R

dimer interface
113V, 114K, 117L, 158R, 159L, 164L, 168I, 174N, 175D, 176V, 177N, 178R, 179V, 180M, 184L, 185G, 194R, 195V, 198D, 201E, 202N, 203N, 264A, 266Q, 267S, 268F, 278G, 279T, 280L, 281T, 406T
CDD
cd00831 (CHS_like)

195V

dimer interface
113V, 114K, 117L, 158R, 159L, 164L, 168I, 174N, 175D, 176V, 177N, 178R, 179V, 180M, 184L, 185G, 194R, 195V, 198D, 201E, 202N, 203N, 264A, 266Q, 267S, 268F, 278G, 279T, 280L, 281T, 406T
CDD
cd00831 (CHS_like)

198D

dimer interface
113V, 114K, 117L, 158R, 159L, 164L, 168I, 174N, 175D, 176V, 177N, 178R, 179V, 180M, 184L, 185G, 194R, 195V, 198D, 201E, 202N, 203N, 264A, 266Q, 267S, 268F, 278G, 279T, 280L, 281T, 406T
CDD
cd00831 (CHS_like)

201E

dimer interface
113V, 114K, 117L, 158R, 159L, 164L, 168I, 174N, 175D, 176V, 177N, 178R, 179V, 180M, 184L, 185G, 194R, 195V, 198D, 201E, 202N, 203N, 264A, 266Q, 267S, 268F, 278G, 279T, 280L, 281T, 406T
CDD
cd00831 (CHS_like)

202N

dimer interface
113V, 114K, 117L, 158R, 159L, 164L, 168I, 174N, 175D, 176V, 177N, 178R, 179V, 180M, 184L, 185G, 194R, 195V, 198D, 201E, 202N, 203N, 264A, 266Q, 267S, 268F, 278G, 279T, 280L, 281T, 406T
CDD
cd00831 (CHS_like)

203N

dimer interface
113V, 114K, 117L, 158R, 159L, 164L, 168I, 174N, 175D, 176V, 177N, 178R, 179V, 180M, 184L, 185G, 194R, 195V, 198D, 201E, 202N, 203N, 264A, 266Q, 267S, 268F, 278G, 279T, 280L, 281T, 406T
CDD
cd00831 (CHS_like)

264A

dimer interface
113V, 114K, 117L, 158R, 159L, 164L, 168I, 174N, 175D, 176V, 177N, 178R, 179V, 180M, 184L, 185G, 194R, 195V, 198D, 201E, 202N, 203N, 264A, 266Q, 267S, 268F, 278G, 279T, 280L, 281T, 406T
CDD
cd00831 (CHS_like)

266Q

dimer interface
113V, 114K, 117L, 158R, 159L, 164L, 168I, 174N, 175D, 176V, 177N, 178R, 179V, 180M, 184L, 185G, 194R, 195V, 198D, 201E, 202N, 203N, 264A, 266Q, 267S, 268F, 278G, 279T, 280L, 281T, 406T
CDD
cd00831 (CHS_like)

267S

dimer interface
113V, 114K, 117L, 158R, 159L, 164L, 168I, 174N, 175D, 176V, 177N, 178R, 179V, 180M, 184L, 185G, 194R, 195V, 198D, 201E, 202N, 203N, 264A, 266Q, 267S, 268F, 278G, 279T, 280L, 281T, 406T
CDD
cd00831 (CHS_like)

268F

dimer interface
113V, 114K, 117L, 158R, 159L, 164L, 168I, 174N, 175D, 176V, 177N, 178R, 179V, 180M, 184L, 185G, 194R, 195V, 198D, 201E, 202N, 203N, 264A, 266Q, 267S, 268F, 278G, 279T, 280L, 281T, 406T
CDD
cd00831 (CHS_like)

278G

dimer interface
113V, 114K, 117L, 158R, 159L, 164L, 168I, 174N, 175D, 176V, 177N, 178R, 179V, 180M, 184L, 185G, 194R, 195V, 198D, 201E, 202N, 203N, 264A, 266Q, 267S, 268F, 278G, 279T, 280L, 281T, 406T
CDD
cd00831 (CHS_like)

279T

dimer interface
113V, 114K, 117L, 158R, 159L, 164L, 168I, 174N, 175D, 176V, 177N, 178R, 179V, 180M, 184L, 185G, 194R, 195V, 198D, 201E, 202N, 203N, 264A, 266Q, 267S, 268F, 278G, 279T, 280L, 281T, 406T
CDD
cd00831 (CHS_like)

280L

dimer interface
113V, 114K, 117L, 158R, 159L, 164L, 168I, 174N, 175D, 176V, 177N, 178R, 179V, 180M, 184L, 185G, 194R, 195V, 198D, 201E, 202N, 203N, 264A, 266Q, 267S, 268F, 278G, 279T, 280L, 281T, 406T
CDD
cd00831 (CHS_like)

281T

dimer interface
113V, 114K, 117L, 158R, 159L, 164L, 168I, 174N, 175D, 176V, 177N, 178R, 179V, 180M, 184L, 185G, 194R, 195V, 198D, 201E, 202N, 203N, 264A, 266Q, 267S, 268F, 278G, 279T, 280L, 281T, 406T
CDD
cd00831 (CHS_like)

406T

dimer interface
113V, 114K, 117L, 158R, 159L, 164L, 168I, 174N, 175D, 176V, 177N, 178R, 179V, 180M, 184L, 185G, 194R, 195V, 198D, 201E, 202N, 203N, 264A, 266Q, 267S, 268F, 278G, 279T, 280L, 281T, 406T
CDD
cd00831 (CHS_like)
active site cd00831

186C

active site
186C, 326H, 359N
CDD
cd00831 (CHS_like)

326H

active site
186C, 326H, 359N
CDD
cd00831 (CHS_like)

359N

active site
186C, 326H, 359N
CDD
cd00831 (CHS_like)
product binding si...

214E

product binding site
214E, 215T, 216C, 238G, 276I, 277E, 278G, 286I, 287F, 361N, 403P
CDD
cd00831 (CHS_like)

215T

product binding site
214E, 215T, 216C, 238G, 276I, 277E, 278G, 286I, 287F, 361N, 403P
CDD
cd00831 (CHS_like)

216C

product binding site
214E, 215T, 216C, 238G, 276I, 277E, 278G, 286I, 287F, 361N, 403P
CDD
cd00831 (CHS_like)

238G

product binding site
214E, 215T, 216C, 238G, 276I, 277E, 278G, 286I, 287F, 361N, 403P
CDD
cd00831 (CHS_like)

276I

product binding site
214E, 215T, 216C, 238G, 276I, 277E, 278G, 286I, 287F, 361N, 403P
CDD
cd00831 (CHS_like)

277E

product binding site
214E, 215T, 216C, 238G, 276I, 277E, 278G, 286I, 287F, 361N, 403P
CDD
cd00831 (CHS_like)

278G

product binding site
214E, 215T, 216C, 238G, 276I, 277E, 278G, 286I, 287F, 361N, 403P
CDD
cd00831 (CHS_like)

286I

product binding site
214E, 215T, 216C, 238G, 276I, 277E, 278G, 286I, 287F, 361N, 403P
CDD
cd00831 (CHS_like)

287F

product binding site
214E, 215T, 216C, 238G, 276I, 277E, 278G, 286I, 287F, 361N, 403P
CDD
cd00831 (CHS_like)

361N

product binding site
214E, 215T, 216C, 238G, 276I, 277E, 278G, 286I, 287F, 361N, 403P
CDD
cd00831 (CHS_like)

403P

product binding site
214E, 215T, 216C, 238G, 276I, 277E, 278G, 286I, 287F, 361N, 403P
CDD
cd00831 (CHS_like)

GO term prediction

Biological Process

GO:0009058 biosynthetic process

Molecular Function

GO:0016746 transferase activity, transferring acyl groups
GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups

Cellular Component

None predicted.

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Entry type

Status

Per-residue features