Mp3g08120.1

Protein

Length

730 amino acids

Protein family membership

Mini-chromosome maintenance protein (IPR031327)
- DNA replication licensing factor Mcm5 (IPR008048)

Homologous superfamilies

Homologous superfamily
35 - 292
Nucleic acid-binding, OB-fold (IPR012340)
336 - 646
P-loop containing nucleoside triphosphate hydrolase (IPR027417)

1 100 200 300 400 500 600 730

Domains and repeats

Domain
35 - 106
MCM N-terminal domain (IPR027925)
135 - 270
MCM OB domain (IPR033762)
314 - 536
MCM domain (IPR001208)
555 - 645
MCM, AAA-lid domain (IPR041562)

1 100 200 300 400 500 600 730

Detailed signature matches

IPR012340

Nucleic acid-binding, OB-fold
1. SSF50249 (Nucleic a...)
  
  35 - 292
  
  SUPERFAMILY
  SSF50249 (Nucleic acid-binding proteins)
IPR027417

P-loop containing nucleoside triphosphate hydrolase
1. SSF52540 (P-loop co...)
  
  336 - 646
  
  SUPERFAMILY
  SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
IPR031327

Mini-chromosome maintenance protein
1. PTHR11630 (DNA REPL...)
  
  56 - 676
  
  PANTHER
  PTHR11630 (DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER)
2. SM00350 (mcm)
  
  131 - 647
  
  SMART
  SM00350 (mcm)
IPR008048

DNA replication licensing factor Mcm5
1. PR01661 (MCMPROTEIN5)
  
  136 - 151
  
  PRINTS
  PR01661 (MCMPROTEIN5)
  
  640 - 657
  
  PRINTS
  PR01661 (MCMPROTEIN5)
  
  286 - 298
  
  PRINTS
  PR01661 (MCMPROTEIN5)
  
  563 - 578
  
  PRINTS
  PR01661 (MCMPROTEIN5)
  
  162 - 174
  
  PRINTS
  PR01661 (MCMPROTEIN5)
IPR027925

MCM N-terminal domain
1. PF14551 (MCM_N)
  
  35 - 106
  
  Pfam
  PF14551 (MCM_N)
IPR033762

MCM OB domain
1. PF17207 (MCM_OB)
  
  135 - 270
  
  Pfam
  PF17207 (MCM_OB)
IPR001208

MCM domain
1. PS50051 (MCM_2)
  
  326 - 532
  
  PROSITE profiles
  PS50051 (MCM_2)
2. PF00493 (MCM)
  
  314 - 536
  
  Pfam
  PF00493 (MCM)
3. PR01657 (MCMFAMILY)
  
  479 - 491
  
  PRINTS
  PR01657 (MCMFAMILY)
  
  506 - 514
  
  PRINTS
  PR01657 (MCMFAMILY)
  
  427 - 441
  
  PRINTS
  PR01657 (MCMFAMILY)
  
  455 - 468
  
  PRINTS
  PR01657 (MCMFAMILY)
  
  367 - 382
  
  PRINTS
  PR01657 (MCMFAMILY)
IPR041562

MCM, AAA-lid domain
1. PF17855 (MCM_lid)
  
  555 - 645
  
  Pfam
  PF17855 (MCM_lid)
IPR018525

Mini-chromosome maintenance, conserved site
1. PS00847 (MCM_1)
  
  435 - 443
  
  PROSITE patterns
  PS00847 (MCM_1)

no IPR

Unintegrated signatures

G3DSA:2.20.28.10

165 - 216

GENE3D
G3DSA:2.20.28.10 (G3DSA:2.20.28.10)
G3DSA:2.40.50...

217 - 274

GENE3D
G3DSA:2.40.50.140 (G3DSA:2.40.50.140)

135 - 164

GENE3D
G3DSA:2.40.50.140 (G3DSA:2.40.50.140)
G3DSA:3.30.16...

26 - 115

GENE3D
G3DSA:3.30.1640.10 (G3DSA:3.30.1640.10)
G3DSA:3.40.50...

311 - 651

GENE3D
G3DSA:3.40.50.300 (G3DSA:3.40.50.300)
PTHR11630:SF42 (DNA...)

56 - 676

PANTHER
PTHR11630:SF42 (DNA REPLICATION LICENSING FACTOR MCM5)
cd17756 (MCM5)

329 - 645

CDD
cd17756 (MCM5)

Residue annotation

ATP binding site c...

337S

ATP binding site
337S, 338I, 339F, 378P, 379S, 380T, 381A, 382K, 383S, 384Q, 459Q, 509R, 528I, 535V, 608V, 609R
CDD
cd17756 (MCM5)

338I

ATP binding site
337S, 338I, 339F, 378P, 379S, 380T, 381A, 382K, 383S, 384Q, 459Q, 509R, 528I, 535V, 608V, 609R
CDD
cd17756 (MCM5)

339F

ATP binding site
337S, 338I, 339F, 378P, 379S, 380T, 381A, 382K, 383S, 384Q, 459Q, 509R, 528I, 535V, 608V, 609R
CDD
cd17756 (MCM5)

378P

ATP binding site
337S, 338I, 339F, 378P, 379S, 380T, 381A, 382K, 383S, 384Q, 459Q, 509R, 528I, 535V, 608V, 609R
CDD
cd17756 (MCM5)

379S

ATP binding site
337S, 338I, 339F, 378P, 379S, 380T, 381A, 382K, 383S, 384Q, 459Q, 509R, 528I, 535V, 608V, 609R
CDD
cd17756 (MCM5)

380T

ATP binding site
337S, 338I, 339F, 378P, 379S, 380T, 381A, 382K, 383S, 384Q, 459Q, 509R, 528I, 535V, 608V, 609R
CDD
cd17756 (MCM5)

381A

ATP binding site
337S, 338I, 339F, 378P, 379S, 380T, 381A, 382K, 383S, 384Q, 459Q, 509R, 528I, 535V, 608V, 609R
CDD
cd17756 (MCM5)

382K

ATP binding site
337S, 338I, 339F, 378P, 379S, 380T, 381A, 382K, 383S, 384Q, 459Q, 509R, 528I, 535V, 608V, 609R
CDD
cd17756 (MCM5)

383S

ATP binding site
337S, 338I, 339F, 378P, 379S, 380T, 381A, 382K, 383S, 384Q, 459Q, 509R, 528I, 535V, 608V, 609R
CDD
cd17756 (MCM5)

384Q

ATP binding site
337S, 338I, 339F, 378P, 379S, 380T, 381A, 382K, 383S, 384Q, 459Q, 509R, 528I, 535V, 608V, 609R
CDD
cd17756 (MCM5)

459Q

ATP binding site
337S, 338I, 339F, 378P, 379S, 380T, 381A, 382K, 383S, 384Q, 459Q, 509R, 528I, 535V, 608V, 609R
CDD
cd17756 (MCM5)

509R

ATP binding site
337S, 338I, 339F, 378P, 379S, 380T, 381A, 382K, 383S, 384Q, 459Q, 509R, 528I, 535V, 608V, 609R
CDD
cd17756 (MCM5)

528I

ATP binding site
337S, 338I, 339F, 378P, 379S, 380T, 381A, 382K, 383S, 384Q, 459Q, 509R, 528I, 535V, 608V, 609R
CDD
cd17756 (MCM5)

535V

ATP binding site
337S, 338I, 339F, 378P, 379S, 380T, 381A, 382K, 383S, 384Q, 459Q, 509R, 528I, 535V, 608V, 609R
CDD
cd17756 (MCM5)

608V

ATP binding site
337S, 338I, 339F, 378P, 379S, 380T, 381A, 382K, 383S, 384Q, 459Q, 509R, 528I, 535V, 608V, 609R
CDD
cd17756 (MCM5)

609R

ATP binding site
337S, 338I, 339F, 378P, 379S, 380T, 381A, 382K, 383S, 384Q, 459Q, 509R, 528I, 535V, 608V, 609R
CDD
cd17756 (MCM5)
oligomer interface...

337S

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

358K

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

360L

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

361P

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

362D

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

363G

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

364V

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

366L

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

377D

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

378P

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

379S

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

383S

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

384Q

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

387K

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

398Y

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

400S

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

404S

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

405S

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

406A

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

407A

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

415R

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

416D

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

417S

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

421E

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

422F

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

423Y

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

424L

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

425E

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

426G

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

427G

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

430V

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

431L

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

441E

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

448E

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

455E

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

459Q

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

461T

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

463S

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

465A

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

466K

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

467A

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

470T

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

471T

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

472V

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

488G

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

502L

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

505T

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

509R

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

518D

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

520R

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

525D

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

529A

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

533V

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

534N

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

536H

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

537A

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

538T

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

571L

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

576A

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

577N

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

580Q

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

583Y

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

584V

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

587R

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

588K

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

608V

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

611L

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)

615I

oligomer interface
337S, 358K, 360L, 361P, 362D, 363G, 364V, 366L, 377D, 378P, 379S, 383S, 384Q, 387K, 398Y, 400S, 404S, 405S, 406A, 407A, 415R, 416D, 417S, 421E, 422F, 423Y, 424L, 425E, 426G, 427G, 430V, 431L, 441E, 448E, 455E, 459Q, 461T, 463S, 465A, 466K, 467A, 470T, 471T, 472V, 488G, 502L, 505T, 509R, 518D, 520R, 525D, 529A, 533V, 534N, 536H, 537A, 538T, 571L, 576A, 577N, 580Q, 583Y, 584V, 587R, 588K, 608V, 611L, 615I
CDD
cd17756 (MCM5)
nucleic acid bindi...

413V

nucleic acid binding site
413V, 415R, 466K, 467A
CDD
cd17756 (MCM5)

415R

nucleic acid binding site
413V, 415R, 466K, 467A
CDD
cd17756 (MCM5)

466K

nucleic acid binding site
413V, 415R, 466K, 467A
CDD
cd17756 (MCM5)

467A

nucleic acid binding site
413V, 415R, 466K, 467A
CDD
cd17756 (MCM5)

GO term prediction

Biological Process

GO:0006260 DNA replication
GO:0006270 DNA replication initiation
GO:0032508 DNA duplex unwinding

Molecular Function

GO:0003677 DNA binding
GO:0003688 DNA replication origin binding
GO:0005524 ATP binding

Cellular Component

GO:0005634 nucleus
GO:0042555 MCM complex

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Entry type

Status

Per-residue features