Mp3g22530.1

Protein

Length

414 amino acids

Protein family membership

Polyprenyl synthetase (IPR000092)
- Farnesyl pyrophosphate synthase-like (IPR039702)

Homologous superfamilies

Homologous superfamily
74 - 414
Isoprenoid synthase domain superfamily (IPR008949)

1 50 100 150 200 250 300 350 414

Domains and repeats

None predicted.

Detailed signature matches

IPR008949

Isoprenoid synthase domain superfamily
1. SSF48576 (Terpenoid...)
  
  74 - 413
  
  SUPERFAMILY
  SSF48576 (Terpenoid synthases)
2. G3DSA:1.10.60... (F...)
  
  76 - 414
  
  GENE3D
  G3DSA:1.10.600.10 (Farnesyl Diphosphate Synthase)
IPR000092

Polyprenyl synthetase
1. cd00685 (Trans_IPPS_HT)
  
  106 - 412
  
  CDD
  cd00685 (Trans_IPPS_HT)
2. PF00348 (polyprenyl...)
  
  106 - 368
  
  Pfam
  PF00348 (polyprenyl_synt)
IPR039702

Farnesyl pyrophosphate synthase-like
1. PTHR11525 (FARNESYL...)
  
  73 - 414
  
  PANTHER
  PTHR11525 (FARNESYL-PYROPHOSPHATE SYNTHETASE)
IPR033749

Polyprenyl synthetase, conserved site
1. PS00723 (POLYPRENYL...)
  
  161 - 175
  
  PROSITE patterns
  PS00723 (POLYPRENYL_SYNTHASE_1)
2. PS00444 (POLYPRENYL...)
  
  296 - 308
  
  PROSITE patterns
  PS00444 (POLYPRENYL_SYNTHASE_2)

no IPR

Unintegrated signatures

PTHR11525:SF11 (FAR...)

73 - 414

PANTHER
PTHR11525:SF11 (FARNESYL PYROPHOSPHATE SYNTHASE)
SFLDG01017 (Polypre...)

76 - 412

SFLD
SFLDG01017 (Polyprenyl_Transferase_Like)
SFLDS00005 (Isopren...)

76 - 412

SFLD
SFLDS00005 (Isoprenoid_Synthase_Type_I)

Residue annotation

SFLDG01017

119K

Stabilizes fully closed conformation via electrostatic interaction with C-terminal carboxylate of IPP
119K
SFLD
SFLDG01017 (Polyprenyl_Transferase_Like)
substrate binding ...

156L

substrate binding pocket
156L, 159Y, 160F, 161L, 163E, 164D, 165D, 167M, 168D, 173R, 174R, 232Q, 235D, 261K, 262T, 265Y, 304D, 305D, 308D, 318K, 322D, 327K
CDD
cd00685 (Trans_IPPS_HT)

159Y

substrate binding pocket
156L, 159Y, 160F, 161L, 163E, 164D, 165D, 167M, 168D, 173R, 174R, 232Q, 235D, 261K, 262T, 265Y, 304D, 305D, 308D, 318K, 322D, 327K
CDD
cd00685 (Trans_IPPS_HT)

160F

substrate binding pocket
156L, 159Y, 160F, 161L, 163E, 164D, 165D, 167M, 168D, 173R, 174R, 232Q, 235D, 261K, 262T, 265Y, 304D, 305D, 308D, 318K, 322D, 327K
CDD
cd00685 (Trans_IPPS_HT)

161L

substrate binding pocket
156L, 159Y, 160F, 161L, 163E, 164D, 165D, 167M, 168D, 173R, 174R, 232Q, 235D, 261K, 262T, 265Y, 304D, 305D, 308D, 318K, 322D, 327K
CDD
cd00685 (Trans_IPPS_HT)

163E

substrate binding pocket
156L, 159Y, 160F, 161L, 163E, 164D, 165D, 167M, 168D, 173R, 174R, 232Q, 235D, 261K, 262T, 265Y, 304D, 305D, 308D, 318K, 322D, 327K
CDD
cd00685 (Trans_IPPS_HT)

164D

substrate binding pocket
156L, 159Y, 160F, 161L, 163E, 164D, 165D, 167M, 168D, 173R, 174R, 232Q, 235D, 261K, 262T, 265Y, 304D, 305D, 308D, 318K, 322D, 327K
CDD
cd00685 (Trans_IPPS_HT)

165D

substrate binding pocket
156L, 159Y, 160F, 161L, 163E, 164D, 165D, 167M, 168D, 173R, 174R, 232Q, 235D, 261K, 262T, 265Y, 304D, 305D, 308D, 318K, 322D, 327K
CDD
cd00685 (Trans_IPPS_HT)

167M

substrate binding pocket
156L, 159Y, 160F, 161L, 163E, 164D, 165D, 167M, 168D, 173R, 174R, 232Q, 235D, 261K, 262T, 265Y, 304D, 305D, 308D, 318K, 322D, 327K
CDD
cd00685 (Trans_IPPS_HT)

168D

substrate binding pocket
156L, 159Y, 160F, 161L, 163E, 164D, 165D, 167M, 168D, 173R, 174R, 232Q, 235D, 261K, 262T, 265Y, 304D, 305D, 308D, 318K, 322D, 327K
CDD
cd00685 (Trans_IPPS_HT)

173R

substrate binding pocket
156L, 159Y, 160F, 161L, 163E, 164D, 165D, 167M, 168D, 173R, 174R, 232Q, 235D, 261K, 262T, 265Y, 304D, 305D, 308D, 318K, 322D, 327K
CDD
cd00685 (Trans_IPPS_HT)

174R

substrate binding pocket
156L, 159Y, 160F, 161L, 163E, 164D, 165D, 167M, 168D, 173R, 174R, 232Q, 235D, 261K, 262T, 265Y, 304D, 305D, 308D, 318K, 322D, 327K
CDD
cd00685 (Trans_IPPS_HT)

232Q

substrate binding pocket
156L, 159Y, 160F, 161L, 163E, 164D, 165D, 167M, 168D, 173R, 174R, 232Q, 235D, 261K, 262T, 265Y, 304D, 305D, 308D, 318K, 322D, 327K
CDD
cd00685 (Trans_IPPS_HT)

235D

substrate binding pocket
156L, 159Y, 160F, 161L, 163E, 164D, 165D, 167M, 168D, 173R, 174R, 232Q, 235D, 261K, 262T, 265Y, 304D, 305D, 308D, 318K, 322D, 327K
CDD
cd00685 (Trans_IPPS_HT)

261K

substrate binding pocket
156L, 159Y, 160F, 161L, 163E, 164D, 165D, 167M, 168D, 173R, 174R, 232Q, 235D, 261K, 262T, 265Y, 304D, 305D, 308D, 318K, 322D, 327K
CDD
cd00685 (Trans_IPPS_HT)

262T

substrate binding pocket
156L, 159Y, 160F, 161L, 163E, 164D, 165D, 167M, 168D, 173R, 174R, 232Q, 235D, 261K, 262T, 265Y, 304D, 305D, 308D, 318K, 322D, 327K
CDD
cd00685 (Trans_IPPS_HT)

265Y

substrate binding pocket
156L, 159Y, 160F, 161L, 163E, 164D, 165D, 167M, 168D, 173R, 174R, 232Q, 235D, 261K, 262T, 265Y, 304D, 305D, 308D, 318K, 322D, 327K
CDD
cd00685 (Trans_IPPS_HT)

304D

substrate binding pocket
156L, 159Y, 160F, 161L, 163E, 164D, 165D, 167M, 168D, 173R, 174R, 232Q, 235D, 261K, 262T, 265Y, 304D, 305D, 308D, 318K, 322D, 327K
CDD
cd00685 (Trans_IPPS_HT)

305D

substrate binding pocket
156L, 159Y, 160F, 161L, 163E, 164D, 165D, 167M, 168D, 173R, 174R, 232Q, 235D, 261K, 262T, 265Y, 304D, 305D, 308D, 318K, 322D, 327K
CDD
cd00685 (Trans_IPPS_HT)

308D

substrate binding pocket
156L, 159Y, 160F, 161L, 163E, 164D, 165D, 167M, 168D, 173R, 174R, 232Q, 235D, 261K, 262T, 265Y, 304D, 305D, 308D, 318K, 322D, 327K
CDD
cd00685 (Trans_IPPS_HT)

318K

substrate binding pocket
156L, 159Y, 160F, 161L, 163E, 164D, 165D, 167M, 168D, 173R, 174R, 232Q, 235D, 261K, 262T, 265Y, 304D, 305D, 308D, 318K, 322D, 327K
CDD
cd00685 (Trans_IPPS_HT)

322D

substrate binding pocket
156L, 159Y, 160F, 161L, 163E, 164D, 165D, 167M, 168D, 173R, 174R, 232Q, 235D, 261K, 262T, 265Y, 304D, 305D, 308D, 318K, 322D, 327K
CDD
cd00685 (Trans_IPPS_HT)

327K

substrate binding pocket
156L, 159Y, 160F, 161L, 163E, 164D, 165D, 167M, 168D, 173R, 174R, 232Q, 235D, 261K, 262T, 265Y, 304D, 305D, 308D, 318K, 322D, 327K
CDD
cd00685 (Trans_IPPS_HT)
chain length deter...

159Y

chain length determination region
159Y, 160F, 161L, 162V, 163E, 164D, 165D, 166I, 167M, 168D
CDD
cd00685 (Trans_IPPS_HT)

160F

chain length determination region
159Y, 160F, 161L, 162V, 163E, 164D, 165D, 166I, 167M, 168D
CDD
cd00685 (Trans_IPPS_HT)

161L

chain length determination region
159Y, 160F, 161L, 162V, 163E, 164D, 165D, 166I, 167M, 168D
CDD
cd00685 (Trans_IPPS_HT)

162V

chain length determination region
159Y, 160F, 161L, 162V, 163E, 164D, 165D, 166I, 167M, 168D
CDD
cd00685 (Trans_IPPS_HT)

163E

chain length determination region
159Y, 160F, 161L, 162V, 163E, 164D, 165D, 166I, 167M, 168D
CDD
cd00685 (Trans_IPPS_HT)

164D

chain length determination region
159Y, 160F, 161L, 162V, 163E, 164D, 165D, 166I, 167M, 168D
CDD
cd00685 (Trans_IPPS_HT)

165D

chain length determination region
159Y, 160F, 161L, 162V, 163E, 164D, 165D, 166I, 167M, 168D
CDD
cd00685 (Trans_IPPS_HT)

166I

chain length determination region
159Y, 160F, 161L, 162V, 163E, 164D, 165D, 166I, 167M, 168D
CDD
cd00685 (Trans_IPPS_HT)

167M

chain length determination region
159Y, 160F, 161L, 162V, 163E, 164D, 165D, 166I, 167M, 168D
CDD
cd00685 (Trans_IPPS_HT)

168D

chain length determination region
159Y, 160F, 161L, 162V, 163E, 164D, 165D, 166I, 167M, 168D
CDD
cd00685 (Trans_IPPS_HT)
SFLDG01017

164D

Metal ligand
164D
SFLD
SFLDG01017 (Polyprenyl_Transferase_Like)
aspartate-rich reg...

164D

aspartate-rich region 1
164D, 165D, 168D, 173R, 174R, 235D, 261K
CDD
cd00685 (Trans_IPPS_HT)

165D

aspartate-rich region 1
164D, 165D, 168D, 173R, 174R, 235D, 261K
CDD
cd00685 (Trans_IPPS_HT)

168D

aspartate-rich region 1
164D, 165D, 168D, 173R, 174R, 235D, 261K
CDD
cd00685 (Trans_IPPS_HT)

173R

aspartate-rich region 1
164D, 165D, 168D, 173R, 174R, 235D, 261K
CDD
cd00685 (Trans_IPPS_HT)

174R

aspartate-rich region 1
164D, 165D, 168D, 173R, 174R, 235D, 261K
CDD
cd00685 (Trans_IPPS_HT)

235D

aspartate-rich region 1
164D, 165D, 168D, 173R, 174R, 235D, 261K
CDD
cd00685 (Trans_IPPS_HT)

261K

aspartate-rich region 1
164D, 165D, 168D, 173R, 174R, 235D, 261K
CDD
cd00685 (Trans_IPPS_HT)
SFLDS00005

164D

164D, 168D, 304D
SFLD
SFLDS00005 (Isoprenoid_Synthase_Type_I)

168D

164D, 168D, 304D
SFLD
SFLDS00005 (Isoprenoid_Synthase_Type_I)

304D

164D, 168D, 304D
SFLD
SFLDS00005 (Isoprenoid_Synthase_Type_I)
catalytic residues...

164D

catalytic residues
164D, 165D, 168D, 173R, 174R, 261K, 304D, 305D
CDD
cd00685 (Trans_IPPS_HT)

165D

catalytic residues
164D, 165D, 168D, 173R, 174R, 261K, 304D, 305D
CDD
cd00685 (Trans_IPPS_HT)

168D

catalytic residues
164D, 165D, 168D, 173R, 174R, 261K, 304D, 305D
CDD
cd00685 (Trans_IPPS_HT)

173R

catalytic residues
164D, 165D, 168D, 173R, 174R, 261K, 304D, 305D
CDD
cd00685 (Trans_IPPS_HT)

174R

catalytic residues
164D, 165D, 168D, 173R, 174R, 261K, 304D, 305D
CDD
cd00685 (Trans_IPPS_HT)

261K

catalytic residues
164D, 165D, 168D, 173R, 174R, 261K, 304D, 305D
CDD
cd00685 (Trans_IPPS_HT)

304D

catalytic residues
164D, 165D, 168D, 173R, 174R, 261K, 304D, 305D
CDD
cd00685 (Trans_IPPS_HT)

305D

catalytic residues
164D, 165D, 168D, 173R, 174R, 261K, 304D, 305D
CDD
cd00685 (Trans_IPPS_HT)
substrate-Mg2+ bin...

164D

substrate-Mg2+ binding site
164D, 165D, 168D, 173R, 174R, 235D, 261K, 304D, 305D, 308D, 318K, 322D, 327K
CDD
cd00685 (Trans_IPPS_HT)

165D

substrate-Mg2+ binding site
164D, 165D, 168D, 173R, 174R, 235D, 261K, 304D, 305D, 308D, 318K, 322D, 327K
CDD
cd00685 (Trans_IPPS_HT)

168D

substrate-Mg2+ binding site
164D, 165D, 168D, 173R, 174R, 235D, 261K, 304D, 305D, 308D, 318K, 322D, 327K
CDD
cd00685 (Trans_IPPS_HT)

173R

substrate-Mg2+ binding site
164D, 165D, 168D, 173R, 174R, 235D, 261K, 304D, 305D, 308D, 318K, 322D, 327K
CDD
cd00685 (Trans_IPPS_HT)

174R

substrate-Mg2+ binding site
164D, 165D, 168D, 173R, 174R, 235D, 261K, 304D, 305D, 308D, 318K, 322D, 327K
CDD
cd00685 (Trans_IPPS_HT)

235D

substrate-Mg2+ binding site
164D, 165D, 168D, 173R, 174R, 235D, 261K, 304D, 305D, 308D, 318K, 322D, 327K
CDD
cd00685 (Trans_IPPS_HT)

261K

substrate-Mg2+ binding site
164D, 165D, 168D, 173R, 174R, 235D, 261K, 304D, 305D, 308D, 318K, 322D, 327K
CDD
cd00685 (Trans_IPPS_HT)

304D

substrate-Mg2+ binding site
164D, 165D, 168D, 173R, 174R, 235D, 261K, 304D, 305D, 308D, 318K, 322D, 327K
CDD
cd00685 (Trans_IPPS_HT)

305D

substrate-Mg2+ binding site
164D, 165D, 168D, 173R, 174R, 235D, 261K, 304D, 305D, 308D, 318K, 322D, 327K
CDD
cd00685 (Trans_IPPS_HT)

308D

substrate-Mg2+ binding site
164D, 165D, 168D, 173R, 174R, 235D, 261K, 304D, 305D, 308D, 318K, 322D, 327K
CDD
cd00685 (Trans_IPPS_HT)

318K

substrate-Mg2+ binding site
164D, 165D, 168D, 173R, 174R, 235D, 261K, 304D, 305D, 308D, 318K, 322D, 327K
CDD
cd00685 (Trans_IPPS_HT)

322D

substrate-Mg2+ binding site
164D, 165D, 168D, 173R, 174R, 235D, 261K, 304D, 305D, 308D, 318K, 322D, 327K
CDD
cd00685 (Trans_IPPS_HT)

327K

substrate-Mg2+ binding site
164D, 165D, 168D, 173R, 174R, 235D, 261K, 304D, 305D, 308D, 318K, 322D, 327K
CDD
cd00685 (Trans_IPPS_HT)
SFLDG01017

165D

165D
SFLD
SFLDG01017 (Polyprenyl_Transferase_Like)
SFLDG01017

168D

Metal ligand; Stabilizes partially closed conformation via electrostatic interaction with K330
168D
SFLD
SFLDG01017 (Polyprenyl_Transferase_Like)
active site lid re...

170S

active site lid residues
170S, 171V, 172T, 173R, 174R, 175G, 176Q, 177P, 178C, 179W, 180Y, 181K, 182I, 183P, 184K, 311G, 312D, 318K, 319I, 320G, 321T, 322D, 325D, 326T, 327K, 328C, 329S
CDD
cd00685 (Trans_IPPS_HT)

171V

active site lid residues
170S, 171V, 172T, 173R, 174R, 175G, 176Q, 177P, 178C, 179W, 180Y, 181K, 182I, 183P, 184K, 311G, 312D, 318K, 319I, 320G, 321T, 322D, 325D, 326T, 327K, 328C, 329S
CDD
cd00685 (Trans_IPPS_HT)

172T

active site lid residues
170S, 171V, 172T, 173R, 174R, 175G, 176Q, 177P, 178C, 179W, 180Y, 181K, 182I, 183P, 184K, 311G, 312D, 318K, 319I, 320G, 321T, 322D, 325D, 326T, 327K, 328C, 329S
CDD
cd00685 (Trans_IPPS_HT)

173R

active site lid residues
170S, 171V, 172T, 173R, 174R, 175G, 176Q, 177P, 178C, 179W, 180Y, 181K, 182I, 183P, 184K, 311G, 312D, 318K, 319I, 320G, 321T, 322D, 325D, 326T, 327K, 328C, 329S
CDD
cd00685 (Trans_IPPS_HT)

174R

active site lid residues
170S, 171V, 172T, 173R, 174R, 175G, 176Q, 177P, 178C, 179W, 180Y, 181K, 182I, 183P, 184K, 311G, 312D, 318K, 319I, 320G, 321T, 322D, 325D, 326T, 327K, 328C, 329S
CDD
cd00685 (Trans_IPPS_HT)

175G

active site lid residues
170S, 171V, 172T, 173R, 174R, 175G, 176Q, 177P, 178C, 179W, 180Y, 181K, 182I, 183P, 184K, 311G, 312D, 318K, 319I, 320G, 321T, 322D, 325D, 326T, 327K, 328C, 329S
CDD
cd00685 (Trans_IPPS_HT)

176Q

active site lid residues
170S, 171V, 172T, 173R, 174R, 175G, 176Q, 177P, 178C, 179W, 180Y, 181K, 182I, 183P, 184K, 311G, 312D, 318K, 319I, 320G, 321T, 322D, 325D, 326T, 327K, 328C, 329S
CDD
cd00685 (Trans_IPPS_HT)

177P

active site lid residues
170S, 171V, 172T, 173R, 174R, 175G, 176Q, 177P, 178C, 179W, 180Y, 181K, 182I, 183P, 184K, 311G, 312D, 318K, 319I, 320G, 321T, 322D, 325D, 326T, 327K, 328C, 329S
CDD
cd00685 (Trans_IPPS_HT)

178C

active site lid residues
170S, 171V, 172T, 173R, 174R, 175G, 176Q, 177P, 178C, 179W, 180Y, 181K, 182I, 183P, 184K, 311G, 312D, 318K, 319I, 320G, 321T, 322D, 325D, 326T, 327K, 328C, 329S
CDD
cd00685 (Trans_IPPS_HT)

179W

active site lid residues
170S, 171V, 172T, 173R, 174R, 175G, 176Q, 177P, 178C, 179W, 180Y, 181K, 182I, 183P, 184K, 311G, 312D, 318K, 319I, 320G, 321T, 322D, 325D, 326T, 327K, 328C, 329S
CDD
cd00685 (Trans_IPPS_HT)

180Y

active site lid residues
170S, 171V, 172T, 173R, 174R, 175G, 176Q, 177P, 178C, 179W, 180Y, 181K, 182I, 183P, 184K, 311G, 312D, 318K, 319I, 320G, 321T, 322D, 325D, 326T, 327K, 328C, 329S
CDD
cd00685 (Trans_IPPS_HT)

181K

active site lid residues
170S, 171V, 172T, 173R, 174R, 175G, 176Q, 177P, 178C, 179W, 180Y, 181K, 182I, 183P, 184K, 311G, 312D, 318K, 319I, 320G, 321T, 322D, 325D, 326T, 327K, 328C, 329S
CDD
cd00685 (Trans_IPPS_HT)

182I

active site lid residues
170S, 171V, 172T, 173R, 174R, 175G, 176Q, 177P, 178C, 179W, 180Y, 181K, 182I, 183P, 184K, 311G, 312D, 318K, 319I, 320G, 321T, 322D, 325D, 326T, 327K, 328C, 329S
CDD
cd00685 (Trans_IPPS_HT)

183P

active site lid residues
170S, 171V, 172T, 173R, 174R, 175G, 176Q, 177P, 178C, 179W, 180Y, 181K, 182I, 183P, 184K, 311G, 312D, 318K, 319I, 320G, 321T, 322D, 325D, 326T, 327K, 328C, 329S
CDD
cd00685 (Trans_IPPS_HT)

184K

active site lid residues
170S, 171V, 172T, 173R, 174R, 175G, 176Q, 177P, 178C, 179W, 180Y, 181K, 182I, 183P, 184K, 311G, 312D, 318K, 319I, 320G, 321T, 322D, 325D, 326T, 327K, 328C, 329S
CDD
cd00685 (Trans_IPPS_HT)

311G

active site lid residues
170S, 171V, 172T, 173R, 174R, 175G, 176Q, 177P, 178C, 179W, 180Y, 181K, 182I, 183P, 184K, 311G, 312D, 318K, 319I, 320G, 321T, 322D, 325D, 326T, 327K, 328C, 329S
CDD
cd00685 (Trans_IPPS_HT)

312D

active site lid residues
170S, 171V, 172T, 173R, 174R, 175G, 176Q, 177P, 178C, 179W, 180Y, 181K, 182I, 183P, 184K, 311G, 312D, 318K, 319I, 320G, 321T, 322D, 325D, 326T, 327K, 328C, 329S
CDD
cd00685 (Trans_IPPS_HT)

318K

active site lid residues
170S, 171V, 172T, 173R, 174R, 175G, 176Q, 177P, 178C, 179W, 180Y, 181K, 182I, 183P, 184K, 311G, 312D, 318K, 319I, 320G, 321T, 322D, 325D, 326T, 327K, 328C, 329S
CDD
cd00685 (Trans_IPPS_HT)

319I

active site lid residues
170S, 171V, 172T, 173R, 174R, 175G, 176Q, 177P, 178C, 179W, 180Y, 181K, 182I, 183P, 184K, 311G, 312D, 318K, 319I, 320G, 321T, 322D, 325D, 326T, 327K, 328C, 329S
CDD
cd00685 (Trans_IPPS_HT)

320G

active site lid residues
170S, 171V, 172T, 173R, 174R, 175G, 176Q, 177P, 178C, 179W, 180Y, 181K, 182I, 183P, 184K, 311G, 312D, 318K, 319I, 320G, 321T, 322D, 325D, 326T, 327K, 328C, 329S
CDD
cd00685 (Trans_IPPS_HT)

321T

active site lid residues
170S, 171V, 172T, 173R, 174R, 175G, 176Q, 177P, 178C, 179W, 180Y, 181K, 182I, 183P, 184K, 311G, 312D, 318K, 319I, 320G, 321T, 322D, 325D, 326T, 327K, 328C, 329S
CDD
cd00685 (Trans_IPPS_HT)

322D

active site lid residues
170S, 171V, 172T, 173R, 174R, 175G, 176Q, 177P, 178C, 179W, 180Y, 181K, 182I, 183P, 184K, 311G, 312D, 318K, 319I, 320G, 321T, 322D, 325D, 326T, 327K, 328C, 329S
CDD
cd00685 (Trans_IPPS_HT)

325D

active site lid residues
170S, 171V, 172T, 173R, 174R, 175G, 176Q, 177P, 178C, 179W, 180Y, 181K, 182I, 183P, 184K, 311G, 312D, 318K, 319I, 320G, 321T, 322D, 325D, 326T, 327K, 328C, 329S
CDD
cd00685 (Trans_IPPS_HT)

326T

active site lid residues
170S, 171V, 172T, 173R, 174R, 175G, 176Q, 177P, 178C, 179W, 180Y, 181K, 182I, 183P, 184K, 311G, 312D, 318K, 319I, 320G, 321T, 322D, 325D, 326T, 327K, 328C, 329S
CDD
cd00685 (Trans_IPPS_HT)

327K

active site lid residues
170S, 171V, 172T, 173R, 174R, 175G, 176Q, 177P, 178C, 179W, 180Y, 181K, 182I, 183P, 184K, 311G, 312D, 318K, 319I, 320G, 321T, 322D, 325D, 326T, 327K, 328C, 329S
CDD
cd00685 (Trans_IPPS_HT)

328C

active site lid residues
170S, 171V, 172T, 173R, 174R, 175G, 176Q, 177P, 178C, 179W, 180Y, 181K, 182I, 183P, 184K, 311G, 312D, 318K, 319I, 320G, 321T, 322D, 325D, 326T, 327K, 328C, 329S
CDD
cd00685 (Trans_IPPS_HT)

329S

active site lid residues
170S, 171V, 172T, 173R, 174R, 175G, 176Q, 177P, 178C, 179W, 180Y, 181K, 182I, 183P, 184K, 311G, 312D, 318K, 319I, 320G, 321T, 322D, 325D, 326T, 327K, 328C, 329S
CDD
cd00685 (Trans_IPPS_HT)
SFLDG01017

173R

Hydrogen bonds to substrate diphosphate
173R
SFLD
SFLDG01017 (Polyprenyl_Transferase_Like)
SFLDG01017

235D

Stabilizes partially closed conformation via electrostatic interactions with K330
235D
SFLD
SFLDG01017 (Polyprenyl_Transferase_Like)
SFLDG01017

261K

Hydrogen bonds to substrate diphosphate
261K
SFLD
SFLDG01017 (Polyprenyl_Transferase_Like)
SFLDG01017

304D

Metal ligand
304D
SFLD
SFLDG01017 (Polyprenyl_Transferase_Like)
aspartate-rich reg...

304D

aspartate-rich region 2
304D, 305D, 308D, 318K, 322D, 327K
CDD
cd00685 (Trans_IPPS_HT)

305D

aspartate-rich region 2
304D, 305D, 308D, 318K, 322D, 327K
CDD
cd00685 (Trans_IPPS_HT)

308D

aspartate-rich region 2
304D, 305D, 308D, 318K, 322D, 327K
CDD
cd00685 (Trans_IPPS_HT)

318K

aspartate-rich region 2
304D, 305D, 308D, 318K, 322D, 327K
CDD
cd00685 (Trans_IPPS_HT)

322D

aspartate-rich region 2
304D, 305D, 308D, 318K, 322D, 327K
CDD
cd00685 (Trans_IPPS_HT)

327K

aspartate-rich region 2
304D, 305D, 308D, 318K, 322D, 327K
CDD
cd00685 (Trans_IPPS_HT)
SFLDG01017

305D

Metal ligand (via water)
305D
SFLD
SFLDG01017 (Polyprenyl_Transferase_Like)

GO term prediction

Biological Process

GO:0008299 isoprenoid biosynthetic process

Molecular Function

GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups

Cellular Component