Mp3g22530.2

Protein

Length

413 amino acids

Protein family membership

Polyprenyl synthetase (IPR000092)
- Farnesyl pyrophosphate synthase-like (IPR039702)

Homologous superfamilies

Homologous superfamily
73 - 413
Isoprenoid synthase domain superfamily (IPR008949)

1 50 100 150 200 250 300 350 413

Domains and repeats

None predicted.

Detailed signature matches

IPR008949

Isoprenoid synthase domain superfamily
1. SSF48576 (Terpenoid...)
  
  73 - 412
  
  SUPERFAMILY
  SSF48576 (Terpenoid synthases)
2. G3DSA:1.10.60... (F...)
  
  75 - 413
  
  GENE3D
  G3DSA:1.10.600.10 (Farnesyl Diphosphate Synthase)
IPR000092

Polyprenyl synthetase
1. cd00685 (Trans_IPPS_HT)
  
  105 - 411
  
  CDD
  cd00685 (Trans_IPPS_HT)
2. PF00348 (polyprenyl...)
  
  105 - 367
  
  Pfam
  PF00348 (polyprenyl_synt)
IPR039702

Farnesyl pyrophosphate synthase-like
1. PTHR11525 (FARNESYL...)
  
  72 - 413
  
  PANTHER
  PTHR11525 (FARNESYL-PYROPHOSPHATE SYNTHETASE)
IPR033749

Polyprenyl synthetase, conserved site
1. PS00723 (POLYPRENYL...)
  
  160 - 174
  
  PROSITE patterns
  PS00723 (POLYPRENYL_SYNTHASE_1)
2. PS00444 (POLYPRENYL...)
  
  295 - 307
  
  PROSITE patterns
  PS00444 (POLYPRENYL_SYNTHASE_2)

no IPR

Unintegrated signatures

PTHR11525:SF11 (FAR...)

72 - 413

PANTHER
PTHR11525:SF11 (FARNESYL PYROPHOSPHATE SYNTHASE)
SFLDG01017 (Polypre...)

75 - 411

SFLD
SFLDG01017 (Polyprenyl_Transferase_Like)
SFLDS00005 (Isopren...)

75 - 411

SFLD
SFLDS00005 (Isoprenoid_Synthase_Type_I)

Residue annotation

SFLDG01017

118K

Stabilizes fully closed conformation via electrostatic interaction with C-terminal carboxylate of IPP
118K
SFLD
SFLDG01017 (Polyprenyl_Transferase_Like)
substrate binding ...

155L

substrate binding pocket
155L, 158Y, 159F, 160L, 162E, 163D, 164D, 166M, 167D, 172R, 173R, 231Q, 234D, 260K, 261T, 264Y, 303D, 304D, 307D, 317K, 321D, 326K
CDD
cd00685 (Trans_IPPS_HT)

158Y

substrate binding pocket
155L, 158Y, 159F, 160L, 162E, 163D, 164D, 166M, 167D, 172R, 173R, 231Q, 234D, 260K, 261T, 264Y, 303D, 304D, 307D, 317K, 321D, 326K
CDD
cd00685 (Trans_IPPS_HT)

159F

substrate binding pocket
155L, 158Y, 159F, 160L, 162E, 163D, 164D, 166M, 167D, 172R, 173R, 231Q, 234D, 260K, 261T, 264Y, 303D, 304D, 307D, 317K, 321D, 326K
CDD
cd00685 (Trans_IPPS_HT)

160L

substrate binding pocket
155L, 158Y, 159F, 160L, 162E, 163D, 164D, 166M, 167D, 172R, 173R, 231Q, 234D, 260K, 261T, 264Y, 303D, 304D, 307D, 317K, 321D, 326K
CDD
cd00685 (Trans_IPPS_HT)

162E

substrate binding pocket
155L, 158Y, 159F, 160L, 162E, 163D, 164D, 166M, 167D, 172R, 173R, 231Q, 234D, 260K, 261T, 264Y, 303D, 304D, 307D, 317K, 321D, 326K
CDD
cd00685 (Trans_IPPS_HT)

163D

substrate binding pocket
155L, 158Y, 159F, 160L, 162E, 163D, 164D, 166M, 167D, 172R, 173R, 231Q, 234D, 260K, 261T, 264Y, 303D, 304D, 307D, 317K, 321D, 326K
CDD
cd00685 (Trans_IPPS_HT)

164D

substrate binding pocket
155L, 158Y, 159F, 160L, 162E, 163D, 164D, 166M, 167D, 172R, 173R, 231Q, 234D, 260K, 261T, 264Y, 303D, 304D, 307D, 317K, 321D, 326K
CDD
cd00685 (Trans_IPPS_HT)

166M

substrate binding pocket
155L, 158Y, 159F, 160L, 162E, 163D, 164D, 166M, 167D, 172R, 173R, 231Q, 234D, 260K, 261T, 264Y, 303D, 304D, 307D, 317K, 321D, 326K
CDD
cd00685 (Trans_IPPS_HT)

167D

substrate binding pocket
155L, 158Y, 159F, 160L, 162E, 163D, 164D, 166M, 167D, 172R, 173R, 231Q, 234D, 260K, 261T, 264Y, 303D, 304D, 307D, 317K, 321D, 326K
CDD
cd00685 (Trans_IPPS_HT)

172R

substrate binding pocket
155L, 158Y, 159F, 160L, 162E, 163D, 164D, 166M, 167D, 172R, 173R, 231Q, 234D, 260K, 261T, 264Y, 303D, 304D, 307D, 317K, 321D, 326K
CDD
cd00685 (Trans_IPPS_HT)

173R

substrate binding pocket
155L, 158Y, 159F, 160L, 162E, 163D, 164D, 166M, 167D, 172R, 173R, 231Q, 234D, 260K, 261T, 264Y, 303D, 304D, 307D, 317K, 321D, 326K
CDD
cd00685 (Trans_IPPS_HT)

231Q

substrate binding pocket
155L, 158Y, 159F, 160L, 162E, 163D, 164D, 166M, 167D, 172R, 173R, 231Q, 234D, 260K, 261T, 264Y, 303D, 304D, 307D, 317K, 321D, 326K
CDD
cd00685 (Trans_IPPS_HT)

234D

substrate binding pocket
155L, 158Y, 159F, 160L, 162E, 163D, 164D, 166M, 167D, 172R, 173R, 231Q, 234D, 260K, 261T, 264Y, 303D, 304D, 307D, 317K, 321D, 326K
CDD
cd00685 (Trans_IPPS_HT)

260K

substrate binding pocket
155L, 158Y, 159F, 160L, 162E, 163D, 164D, 166M, 167D, 172R, 173R, 231Q, 234D, 260K, 261T, 264Y, 303D, 304D, 307D, 317K, 321D, 326K
CDD
cd00685 (Trans_IPPS_HT)

261T

substrate binding pocket
155L, 158Y, 159F, 160L, 162E, 163D, 164D, 166M, 167D, 172R, 173R, 231Q, 234D, 260K, 261T, 264Y, 303D, 304D, 307D, 317K, 321D, 326K
CDD
cd00685 (Trans_IPPS_HT)

264Y

substrate binding pocket
155L, 158Y, 159F, 160L, 162E, 163D, 164D, 166M, 167D, 172R, 173R, 231Q, 234D, 260K, 261T, 264Y, 303D, 304D, 307D, 317K, 321D, 326K
CDD
cd00685 (Trans_IPPS_HT)

303D

substrate binding pocket
155L, 158Y, 159F, 160L, 162E, 163D, 164D, 166M, 167D, 172R, 173R, 231Q, 234D, 260K, 261T, 264Y, 303D, 304D, 307D, 317K, 321D, 326K
CDD
cd00685 (Trans_IPPS_HT)

304D

substrate binding pocket
155L, 158Y, 159F, 160L, 162E, 163D, 164D, 166M, 167D, 172R, 173R, 231Q, 234D, 260K, 261T, 264Y, 303D, 304D, 307D, 317K, 321D, 326K
CDD
cd00685 (Trans_IPPS_HT)

307D

substrate binding pocket
155L, 158Y, 159F, 160L, 162E, 163D, 164D, 166M, 167D, 172R, 173R, 231Q, 234D, 260K, 261T, 264Y, 303D, 304D, 307D, 317K, 321D, 326K
CDD
cd00685 (Trans_IPPS_HT)

317K

substrate binding pocket
155L, 158Y, 159F, 160L, 162E, 163D, 164D, 166M, 167D, 172R, 173R, 231Q, 234D, 260K, 261T, 264Y, 303D, 304D, 307D, 317K, 321D, 326K
CDD
cd00685 (Trans_IPPS_HT)

321D

substrate binding pocket
155L, 158Y, 159F, 160L, 162E, 163D, 164D, 166M, 167D, 172R, 173R, 231Q, 234D, 260K, 261T, 264Y, 303D, 304D, 307D, 317K, 321D, 326K
CDD
cd00685 (Trans_IPPS_HT)

326K

substrate binding pocket
155L, 158Y, 159F, 160L, 162E, 163D, 164D, 166M, 167D, 172R, 173R, 231Q, 234D, 260K, 261T, 264Y, 303D, 304D, 307D, 317K, 321D, 326K
CDD
cd00685 (Trans_IPPS_HT)
chain length deter...

158Y

chain length determination region
158Y, 159F, 160L, 161V, 162E, 163D, 164D, 165I, 166M, 167D
CDD
cd00685 (Trans_IPPS_HT)

159F

chain length determination region
158Y, 159F, 160L, 161V, 162E, 163D, 164D, 165I, 166M, 167D
CDD
cd00685 (Trans_IPPS_HT)

160L

chain length determination region
158Y, 159F, 160L, 161V, 162E, 163D, 164D, 165I, 166M, 167D
CDD
cd00685 (Trans_IPPS_HT)

161V

chain length determination region
158Y, 159F, 160L, 161V, 162E, 163D, 164D, 165I, 166M, 167D
CDD
cd00685 (Trans_IPPS_HT)

162E

chain length determination region
158Y, 159F, 160L, 161V, 162E, 163D, 164D, 165I, 166M, 167D
CDD
cd00685 (Trans_IPPS_HT)

163D

chain length determination region
158Y, 159F, 160L, 161V, 162E, 163D, 164D, 165I, 166M, 167D
CDD
cd00685 (Trans_IPPS_HT)

164D

chain length determination region
158Y, 159F, 160L, 161V, 162E, 163D, 164D, 165I, 166M, 167D
CDD
cd00685 (Trans_IPPS_HT)

165I

chain length determination region
158Y, 159F, 160L, 161V, 162E, 163D, 164D, 165I, 166M, 167D
CDD
cd00685 (Trans_IPPS_HT)

166M

chain length determination region
158Y, 159F, 160L, 161V, 162E, 163D, 164D, 165I, 166M, 167D
CDD
cd00685 (Trans_IPPS_HT)

167D

chain length determination region
158Y, 159F, 160L, 161V, 162E, 163D, 164D, 165I, 166M, 167D
CDD
cd00685 (Trans_IPPS_HT)
SFLDG01017

163D

Metal ligand
163D
SFLD
SFLDG01017 (Polyprenyl_Transferase_Like)
aspartate-rich reg...

163D

aspartate-rich region 1
163D, 164D, 167D, 172R, 173R, 234D, 260K
CDD
cd00685 (Trans_IPPS_HT)

164D

aspartate-rich region 1
163D, 164D, 167D, 172R, 173R, 234D, 260K
CDD
cd00685 (Trans_IPPS_HT)

167D

aspartate-rich region 1
163D, 164D, 167D, 172R, 173R, 234D, 260K
CDD
cd00685 (Trans_IPPS_HT)

172R

aspartate-rich region 1
163D, 164D, 167D, 172R, 173R, 234D, 260K
CDD
cd00685 (Trans_IPPS_HT)

173R

aspartate-rich region 1
163D, 164D, 167D, 172R, 173R, 234D, 260K
CDD
cd00685 (Trans_IPPS_HT)

234D

aspartate-rich region 1
163D, 164D, 167D, 172R, 173R, 234D, 260K
CDD
cd00685 (Trans_IPPS_HT)

260K

aspartate-rich region 1
163D, 164D, 167D, 172R, 173R, 234D, 260K
CDD
cd00685 (Trans_IPPS_HT)
SFLDS00005

163D

163D, 167D, 303D
SFLD
SFLDS00005 (Isoprenoid_Synthase_Type_I)

167D

163D, 167D, 303D
SFLD
SFLDS00005 (Isoprenoid_Synthase_Type_I)

303D

163D, 167D, 303D
SFLD
SFLDS00005 (Isoprenoid_Synthase_Type_I)
catalytic residues...

163D

catalytic residues
163D, 164D, 167D, 172R, 173R, 260K, 303D, 304D
CDD
cd00685 (Trans_IPPS_HT)

164D

catalytic residues
163D, 164D, 167D, 172R, 173R, 260K, 303D, 304D
CDD
cd00685 (Trans_IPPS_HT)

167D

catalytic residues
163D, 164D, 167D, 172R, 173R, 260K, 303D, 304D
CDD
cd00685 (Trans_IPPS_HT)

172R

catalytic residues
163D, 164D, 167D, 172R, 173R, 260K, 303D, 304D
CDD
cd00685 (Trans_IPPS_HT)

173R

catalytic residues
163D, 164D, 167D, 172R, 173R, 260K, 303D, 304D
CDD
cd00685 (Trans_IPPS_HT)

260K

catalytic residues
163D, 164D, 167D, 172R, 173R, 260K, 303D, 304D
CDD
cd00685 (Trans_IPPS_HT)

303D

catalytic residues
163D, 164D, 167D, 172R, 173R, 260K, 303D, 304D
CDD
cd00685 (Trans_IPPS_HT)

304D

catalytic residues
163D, 164D, 167D, 172R, 173R, 260K, 303D, 304D
CDD
cd00685 (Trans_IPPS_HT)
substrate-Mg2+ bin...

163D

substrate-Mg2+ binding site
163D, 164D, 167D, 172R, 173R, 234D, 260K, 303D, 304D, 307D, 317K, 321D, 326K
CDD
cd00685 (Trans_IPPS_HT)

164D

substrate-Mg2+ binding site
163D, 164D, 167D, 172R, 173R, 234D, 260K, 303D, 304D, 307D, 317K, 321D, 326K
CDD
cd00685 (Trans_IPPS_HT)

167D

substrate-Mg2+ binding site
163D, 164D, 167D, 172R, 173R, 234D, 260K, 303D, 304D, 307D, 317K, 321D, 326K
CDD
cd00685 (Trans_IPPS_HT)

172R

substrate-Mg2+ binding site
163D, 164D, 167D, 172R, 173R, 234D, 260K, 303D, 304D, 307D, 317K, 321D, 326K
CDD
cd00685 (Trans_IPPS_HT)

173R

substrate-Mg2+ binding site
163D, 164D, 167D, 172R, 173R, 234D, 260K, 303D, 304D, 307D, 317K, 321D, 326K
CDD
cd00685 (Trans_IPPS_HT)

234D

substrate-Mg2+ binding site
163D, 164D, 167D, 172R, 173R, 234D, 260K, 303D, 304D, 307D, 317K, 321D, 326K
CDD
cd00685 (Trans_IPPS_HT)

260K

substrate-Mg2+ binding site
163D, 164D, 167D, 172R, 173R, 234D, 260K, 303D, 304D, 307D, 317K, 321D, 326K
CDD
cd00685 (Trans_IPPS_HT)

303D

substrate-Mg2+ binding site
163D, 164D, 167D, 172R, 173R, 234D, 260K, 303D, 304D, 307D, 317K, 321D, 326K
CDD
cd00685 (Trans_IPPS_HT)

304D

substrate-Mg2+ binding site
163D, 164D, 167D, 172R, 173R, 234D, 260K, 303D, 304D, 307D, 317K, 321D, 326K
CDD
cd00685 (Trans_IPPS_HT)

307D

substrate-Mg2+ binding site
163D, 164D, 167D, 172R, 173R, 234D, 260K, 303D, 304D, 307D, 317K, 321D, 326K
CDD
cd00685 (Trans_IPPS_HT)

317K

substrate-Mg2+ binding site
163D, 164D, 167D, 172R, 173R, 234D, 260K, 303D, 304D, 307D, 317K, 321D, 326K
CDD
cd00685 (Trans_IPPS_HT)

321D

substrate-Mg2+ binding site
163D, 164D, 167D, 172R, 173R, 234D, 260K, 303D, 304D, 307D, 317K, 321D, 326K
CDD
cd00685 (Trans_IPPS_HT)

326K

substrate-Mg2+ binding site
163D, 164D, 167D, 172R, 173R, 234D, 260K, 303D, 304D, 307D, 317K, 321D, 326K
CDD
cd00685 (Trans_IPPS_HT)
SFLDG01017

164D

164D
SFLD
SFLDG01017 (Polyprenyl_Transferase_Like)
SFLDG01017

167D

Metal ligand; Stabilizes partially closed conformation via electrostatic interaction with K330
167D
SFLD
SFLDG01017 (Polyprenyl_Transferase_Like)
active site lid re...

169S

active site lid residues
169S, 170V, 171T, 172R, 173R, 174G, 175Q, 176P, 177C, 178W, 179Y, 180K, 181I, 182P, 183K, 310G, 311D, 317K, 318I, 319G, 320T, 321D, 324D, 325T, 326K, 327C, 328S
CDD
cd00685 (Trans_IPPS_HT)

170V

active site lid residues
169S, 170V, 171T, 172R, 173R, 174G, 175Q, 176P, 177C, 178W, 179Y, 180K, 181I, 182P, 183K, 310G, 311D, 317K, 318I, 319G, 320T, 321D, 324D, 325T, 326K, 327C, 328S
CDD
cd00685 (Trans_IPPS_HT)

171T

active site lid residues
169S, 170V, 171T, 172R, 173R, 174G, 175Q, 176P, 177C, 178W, 179Y, 180K, 181I, 182P, 183K, 310G, 311D, 317K, 318I, 319G, 320T, 321D, 324D, 325T, 326K, 327C, 328S
CDD
cd00685 (Trans_IPPS_HT)

172R

active site lid residues
169S, 170V, 171T, 172R, 173R, 174G, 175Q, 176P, 177C, 178W, 179Y, 180K, 181I, 182P, 183K, 310G, 311D, 317K, 318I, 319G, 320T, 321D, 324D, 325T, 326K, 327C, 328S
CDD
cd00685 (Trans_IPPS_HT)

173R

active site lid residues
169S, 170V, 171T, 172R, 173R, 174G, 175Q, 176P, 177C, 178W, 179Y, 180K, 181I, 182P, 183K, 310G, 311D, 317K, 318I, 319G, 320T, 321D, 324D, 325T, 326K, 327C, 328S
CDD
cd00685 (Trans_IPPS_HT)

174G

active site lid residues
169S, 170V, 171T, 172R, 173R, 174G, 175Q, 176P, 177C, 178W, 179Y, 180K, 181I, 182P, 183K, 310G, 311D, 317K, 318I, 319G, 320T, 321D, 324D, 325T, 326K, 327C, 328S
CDD
cd00685 (Trans_IPPS_HT)

175Q

active site lid residues
169S, 170V, 171T, 172R, 173R, 174G, 175Q, 176P, 177C, 178W, 179Y, 180K, 181I, 182P, 183K, 310G, 311D, 317K, 318I, 319G, 320T, 321D, 324D, 325T, 326K, 327C, 328S
CDD
cd00685 (Trans_IPPS_HT)

176P

active site lid residues
169S, 170V, 171T, 172R, 173R, 174G, 175Q, 176P, 177C, 178W, 179Y, 180K, 181I, 182P, 183K, 310G, 311D, 317K, 318I, 319G, 320T, 321D, 324D, 325T, 326K, 327C, 328S
CDD
cd00685 (Trans_IPPS_HT)

177C

active site lid residues
169S, 170V, 171T, 172R, 173R, 174G, 175Q, 176P, 177C, 178W, 179Y, 180K, 181I, 182P, 183K, 310G, 311D, 317K, 318I, 319G, 320T, 321D, 324D, 325T, 326K, 327C, 328S
CDD
cd00685 (Trans_IPPS_HT)

178W

active site lid residues
169S, 170V, 171T, 172R, 173R, 174G, 175Q, 176P, 177C, 178W, 179Y, 180K, 181I, 182P, 183K, 310G, 311D, 317K, 318I, 319G, 320T, 321D, 324D, 325T, 326K, 327C, 328S
CDD
cd00685 (Trans_IPPS_HT)

179Y

active site lid residues
169S, 170V, 171T, 172R, 173R, 174G, 175Q, 176P, 177C, 178W, 179Y, 180K, 181I, 182P, 183K, 310G, 311D, 317K, 318I, 319G, 320T, 321D, 324D, 325T, 326K, 327C, 328S
CDD
cd00685 (Trans_IPPS_HT)

180K

active site lid residues
169S, 170V, 171T, 172R, 173R, 174G, 175Q, 176P, 177C, 178W, 179Y, 180K, 181I, 182P, 183K, 310G, 311D, 317K, 318I, 319G, 320T, 321D, 324D, 325T, 326K, 327C, 328S
CDD
cd00685 (Trans_IPPS_HT)

181I

active site lid residues
169S, 170V, 171T, 172R, 173R, 174G, 175Q, 176P, 177C, 178W, 179Y, 180K, 181I, 182P, 183K, 310G, 311D, 317K, 318I, 319G, 320T, 321D, 324D, 325T, 326K, 327C, 328S
CDD
cd00685 (Trans_IPPS_HT)

182P

active site lid residues
169S, 170V, 171T, 172R, 173R, 174G, 175Q, 176P, 177C, 178W, 179Y, 180K, 181I, 182P, 183K, 310G, 311D, 317K, 318I, 319G, 320T, 321D, 324D, 325T, 326K, 327C, 328S
CDD
cd00685 (Trans_IPPS_HT)

183K

active site lid residues
169S, 170V, 171T, 172R, 173R, 174G, 175Q, 176P, 177C, 178W, 179Y, 180K, 181I, 182P, 183K, 310G, 311D, 317K, 318I, 319G, 320T, 321D, 324D, 325T, 326K, 327C, 328S
CDD
cd00685 (Trans_IPPS_HT)

310G

active site lid residues
169S, 170V, 171T, 172R, 173R, 174G, 175Q, 176P, 177C, 178W, 179Y, 180K, 181I, 182P, 183K, 310G, 311D, 317K, 318I, 319G, 320T, 321D, 324D, 325T, 326K, 327C, 328S
CDD
cd00685 (Trans_IPPS_HT)

311D

active site lid residues
169S, 170V, 171T, 172R, 173R, 174G, 175Q, 176P, 177C, 178W, 179Y, 180K, 181I, 182P, 183K, 310G, 311D, 317K, 318I, 319G, 320T, 321D, 324D, 325T, 326K, 327C, 328S
CDD
cd00685 (Trans_IPPS_HT)

317K

active site lid residues
169S, 170V, 171T, 172R, 173R, 174G, 175Q, 176P, 177C, 178W, 179Y, 180K, 181I, 182P, 183K, 310G, 311D, 317K, 318I, 319G, 320T, 321D, 324D, 325T, 326K, 327C, 328S
CDD
cd00685 (Trans_IPPS_HT)

318I

active site lid residues
169S, 170V, 171T, 172R, 173R, 174G, 175Q, 176P, 177C, 178W, 179Y, 180K, 181I, 182P, 183K, 310G, 311D, 317K, 318I, 319G, 320T, 321D, 324D, 325T, 326K, 327C, 328S
CDD
cd00685 (Trans_IPPS_HT)

319G

active site lid residues
169S, 170V, 171T, 172R, 173R, 174G, 175Q, 176P, 177C, 178W, 179Y, 180K, 181I, 182P, 183K, 310G, 311D, 317K, 318I, 319G, 320T, 321D, 324D, 325T, 326K, 327C, 328S
CDD
cd00685 (Trans_IPPS_HT)

320T

active site lid residues
169S, 170V, 171T, 172R, 173R, 174G, 175Q, 176P, 177C, 178W, 179Y, 180K, 181I, 182P, 183K, 310G, 311D, 317K, 318I, 319G, 320T, 321D, 324D, 325T, 326K, 327C, 328S
CDD
cd00685 (Trans_IPPS_HT)

321D

active site lid residues
169S, 170V, 171T, 172R, 173R, 174G, 175Q, 176P, 177C, 178W, 179Y, 180K, 181I, 182P, 183K, 310G, 311D, 317K, 318I, 319G, 320T, 321D, 324D, 325T, 326K, 327C, 328S
CDD
cd00685 (Trans_IPPS_HT)

324D

active site lid residues
169S, 170V, 171T, 172R, 173R, 174G, 175Q, 176P, 177C, 178W, 179Y, 180K, 181I, 182P, 183K, 310G, 311D, 317K, 318I, 319G, 320T, 321D, 324D, 325T, 326K, 327C, 328S
CDD
cd00685 (Trans_IPPS_HT)

325T

active site lid residues
169S, 170V, 171T, 172R, 173R, 174G, 175Q, 176P, 177C, 178W, 179Y, 180K, 181I, 182P, 183K, 310G, 311D, 317K, 318I, 319G, 320T, 321D, 324D, 325T, 326K, 327C, 328S
CDD
cd00685 (Trans_IPPS_HT)

326K

active site lid residues
169S, 170V, 171T, 172R, 173R, 174G, 175Q, 176P, 177C, 178W, 179Y, 180K, 181I, 182P, 183K, 310G, 311D, 317K, 318I, 319G, 320T, 321D, 324D, 325T, 326K, 327C, 328S
CDD
cd00685 (Trans_IPPS_HT)

327C

active site lid residues
169S, 170V, 171T, 172R, 173R, 174G, 175Q, 176P, 177C, 178W, 179Y, 180K, 181I, 182P, 183K, 310G, 311D, 317K, 318I, 319G, 320T, 321D, 324D, 325T, 326K, 327C, 328S
CDD
cd00685 (Trans_IPPS_HT)

328S

active site lid residues
169S, 170V, 171T, 172R, 173R, 174G, 175Q, 176P, 177C, 178W, 179Y, 180K, 181I, 182P, 183K, 310G, 311D, 317K, 318I, 319G, 320T, 321D, 324D, 325T, 326K, 327C, 328S
CDD
cd00685 (Trans_IPPS_HT)
SFLDG01017

172R

Hydrogen bonds to substrate diphosphate
172R
SFLD
SFLDG01017 (Polyprenyl_Transferase_Like)
SFLDG01017

234D

Stabilizes partially closed conformation via electrostatic interactions with K330
234D
SFLD
SFLDG01017 (Polyprenyl_Transferase_Like)
SFLDG01017

260K

Hydrogen bonds to substrate diphosphate
260K
SFLD
SFLDG01017 (Polyprenyl_Transferase_Like)
SFLDG01017

303D

Metal ligand
303D
SFLD
SFLDG01017 (Polyprenyl_Transferase_Like)
aspartate-rich reg...

303D

aspartate-rich region 2
303D, 304D, 307D, 317K, 321D, 326K
CDD
cd00685 (Trans_IPPS_HT)

304D

aspartate-rich region 2
303D, 304D, 307D, 317K, 321D, 326K
CDD
cd00685 (Trans_IPPS_HT)

307D

aspartate-rich region 2
303D, 304D, 307D, 317K, 321D, 326K
CDD
cd00685 (Trans_IPPS_HT)

317K

aspartate-rich region 2
303D, 304D, 307D, 317K, 321D, 326K
CDD
cd00685 (Trans_IPPS_HT)

321D

aspartate-rich region 2
303D, 304D, 307D, 317K, 321D, 326K
CDD
cd00685 (Trans_IPPS_HT)

326K

aspartate-rich region 2
303D, 304D, 307D, 317K, 321D, 326K
CDD
cd00685 (Trans_IPPS_HT)
SFLDG01017

304D

Metal ligand (via water)
304D
SFLD
SFLDG01017 (Polyprenyl_Transferase_Like)

GO term prediction

Biological Process

GO:0008299 isoprenoid biosynthetic process

Molecular Function

GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups

Cellular Component