Mp8g02830.1

Protein

Length

327 amino acids

Protein family membership

None predicted.

Homologous superfamilies

Homologous superfamily
1 - 319
NAD(P)-binding domain superfamily (IPR036291)

1 50 100 150 200 250 300 327

Domains and repeats

Domain
7 - 248
NAD-dependent epimerase/dehydratase (IPR001509)

1 50 100 150 200 250 300 327

Detailed signature matches

IPR036291

NAD(P)-binding domain superfamily
1. SSF51735 (NAD(P)-bi...)
  
  1 - 319
  
  SUPERFAMILY
  SSF51735 (NAD(P)-binding Rossmann-fold domains)
IPR001509

NAD-dependent epimerase/dehydratase
1. PF01370 (Epimerase)
  
  7 - 248
  
  Pfam
  PF01370 (Epimerase)

no IPR

Unintegrated signatures

G3DSA:3.40.50...

1 - 327

GENE3D
G3DSA:3.40.50.720 (G3DSA:3.40.50.720)
PTHR10366 (NAD DEPE...)

3 - 323

PANTHER
PTHR10366 (NAD DEPENDENT EPIMERASE/DEHYDRATASE)
PTHR10366:SF575 (AL...)

3 - 323

PANTHER
PTHR10366:SF575 (ALCOHOL DEHYDROGENASE-RELATED)
cd08958 (FR_SDR_e)

6 - 303

CDD
cd08958 (FR_SDR_e)

Residue annotation

NADP binding site ...

10G

NADP binding site
10G, 12N, 13G, 14F, 15L, 34V, 35R, 61A, 62N, 63L, 82V, 83A, 84S, 85P, 86V, 125T, 126S, 166Y, 170K, 193P, 194G, 195V, 196M, 208S
CDD
cd08958 (FR_SDR_e)

12N

NADP binding site
10G, 12N, 13G, 14F, 15L, 34V, 35R, 61A, 62N, 63L, 82V, 83A, 84S, 85P, 86V, 125T, 126S, 166Y, 170K, 193P, 194G, 195V, 196M, 208S
CDD
cd08958 (FR_SDR_e)

13G

NADP binding site
10G, 12N, 13G, 14F, 15L, 34V, 35R, 61A, 62N, 63L, 82V, 83A, 84S, 85P, 86V, 125T, 126S, 166Y, 170K, 193P, 194G, 195V, 196M, 208S
CDD
cd08958 (FR_SDR_e)

14F

NADP binding site
10G, 12N, 13G, 14F, 15L, 34V, 35R, 61A, 62N, 63L, 82V, 83A, 84S, 85P, 86V, 125T, 126S, 166Y, 170K, 193P, 194G, 195V, 196M, 208S
CDD
cd08958 (FR_SDR_e)

15L

NADP binding site
10G, 12N, 13G, 14F, 15L, 34V, 35R, 61A, 62N, 63L, 82V, 83A, 84S, 85P, 86V, 125T, 126S, 166Y, 170K, 193P, 194G, 195V, 196M, 208S
CDD
cd08958 (FR_SDR_e)

34V

NADP binding site
10G, 12N, 13G, 14F, 15L, 34V, 35R, 61A, 62N, 63L, 82V, 83A, 84S, 85P, 86V, 125T, 126S, 166Y, 170K, 193P, 194G, 195V, 196M, 208S
CDD
cd08958 (FR_SDR_e)

35R

NADP binding site
10G, 12N, 13G, 14F, 15L, 34V, 35R, 61A, 62N, 63L, 82V, 83A, 84S, 85P, 86V, 125T, 126S, 166Y, 170K, 193P, 194G, 195V, 196M, 208S
CDD
cd08958 (FR_SDR_e)

61A

NADP binding site
10G, 12N, 13G, 14F, 15L, 34V, 35R, 61A, 62N, 63L, 82V, 83A, 84S, 85P, 86V, 125T, 126S, 166Y, 170K, 193P, 194G, 195V, 196M, 208S
CDD
cd08958 (FR_SDR_e)

62N

NADP binding site
10G, 12N, 13G, 14F, 15L, 34V, 35R, 61A, 62N, 63L, 82V, 83A, 84S, 85P, 86V, 125T, 126S, 166Y, 170K, 193P, 194G, 195V, 196M, 208S
CDD
cd08958 (FR_SDR_e)

63L

NADP binding site
10G, 12N, 13G, 14F, 15L, 34V, 35R, 61A, 62N, 63L, 82V, 83A, 84S, 85P, 86V, 125T, 126S, 166Y, 170K, 193P, 194G, 195V, 196M, 208S
CDD
cd08958 (FR_SDR_e)

82V

NADP binding site
10G, 12N, 13G, 14F, 15L, 34V, 35R, 61A, 62N, 63L, 82V, 83A, 84S, 85P, 86V, 125T, 126S, 166Y, 170K, 193P, 194G, 195V, 196M, 208S
CDD
cd08958 (FR_SDR_e)

83A

NADP binding site
10G, 12N, 13G, 14F, 15L, 34V, 35R, 61A, 62N, 63L, 82V, 83A, 84S, 85P, 86V, 125T, 126S, 166Y, 170K, 193P, 194G, 195V, 196M, 208S
CDD
cd08958 (FR_SDR_e)

84S

NADP binding site
10G, 12N, 13G, 14F, 15L, 34V, 35R, 61A, 62N, 63L, 82V, 83A, 84S, 85P, 86V, 125T, 126S, 166Y, 170K, 193P, 194G, 195V, 196M, 208S
CDD
cd08958 (FR_SDR_e)

85P

NADP binding site
10G, 12N, 13G, 14F, 15L, 34V, 35R, 61A, 62N, 63L, 82V, 83A, 84S, 85P, 86V, 125T, 126S, 166Y, 170K, 193P, 194G, 195V, 196M, 208S
CDD
cd08958 (FR_SDR_e)

86V

NADP binding site
10G, 12N, 13G, 14F, 15L, 34V, 35R, 61A, 62N, 63L, 82V, 83A, 84S, 85P, 86V, 125T, 126S, 166Y, 170K, 193P, 194G, 195V, 196M, 208S
CDD
cd08958 (FR_SDR_e)

125T

NADP binding site
10G, 12N, 13G, 14F, 15L, 34V, 35R, 61A, 62N, 63L, 82V, 83A, 84S, 85P, 86V, 125T, 126S, 166Y, 170K, 193P, 194G, 195V, 196M, 208S
CDD
cd08958 (FR_SDR_e)

126S

NADP binding site
10G, 12N, 13G, 14F, 15L, 34V, 35R, 61A, 62N, 63L, 82V, 83A, 84S, 85P, 86V, 125T, 126S, 166Y, 170K, 193P, 194G, 195V, 196M, 208S
CDD
cd08958 (FR_SDR_e)

166Y

NADP binding site
10G, 12N, 13G, 14F, 15L, 34V, 35R, 61A, 62N, 63L, 82V, 83A, 84S, 85P, 86V, 125T, 126S, 166Y, 170K, 193P, 194G, 195V, 196M, 208S
CDD
cd08958 (FR_SDR_e)

170K

NADP binding site
10G, 12N, 13G, 14F, 15L, 34V, 35R, 61A, 62N, 63L, 82V, 83A, 84S, 85P, 86V, 125T, 126S, 166Y, 170K, 193P, 194G, 195V, 196M, 208S
CDD
cd08958 (FR_SDR_e)

193P

NADP binding site
10G, 12N, 13G, 14F, 15L, 34V, 35R, 61A, 62N, 63L, 82V, 83A, 84S, 85P, 86V, 125T, 126S, 166Y, 170K, 193P, 194G, 195V, 196M, 208S
CDD
cd08958 (FR_SDR_e)

194G

NADP binding site
10G, 12N, 13G, 14F, 15L, 34V, 35R, 61A, 62N, 63L, 82V, 83A, 84S, 85P, 86V, 125T, 126S, 166Y, 170K, 193P, 194G, 195V, 196M, 208S
CDD
cd08958 (FR_SDR_e)

195V

NADP binding site
10G, 12N, 13G, 14F, 15L, 34V, 35R, 61A, 62N, 63L, 82V, 83A, 84S, 85P, 86V, 125T, 126S, 166Y, 170K, 193P, 194G, 195V, 196M, 208S
CDD
cd08958 (FR_SDR_e)

196M

NADP binding site
10G, 12N, 13G, 14F, 15L, 34V, 35R, 61A, 62N, 63L, 82V, 83A, 84S, 85P, 86V, 125T, 126S, 166Y, 170K, 193P, 194G, 195V, 196M, 208S
CDD
cd08958 (FR_SDR_e)

208S

NADP binding site
10G, 12N, 13G, 14F, 15L, 34V, 35R, 61A, 62N, 63L, 82V, 83A, 84S, 85P, 86V, 125T, 126S, 166Y, 170K, 193P, 194G, 195V, 196M, 208S
CDD
cd08958 (FR_SDR_e)
substrate binding ...

86V

substrate binding site
86V, 88A, 127S, 128T, 129A, 132F, 166Y, 193P, 194G, 195V, 208S, 211I, 225N, 229G, 293Y
CDD
cd08958 (FR_SDR_e)

88A

substrate binding site
86V, 88A, 127S, 128T, 129A, 132F, 166Y, 193P, 194G, 195V, 208S, 211I, 225N, 229G, 293Y
CDD
cd08958 (FR_SDR_e)

127S

substrate binding site
86V, 88A, 127S, 128T, 129A, 132F, 166Y, 193P, 194G, 195V, 208S, 211I, 225N, 229G, 293Y
CDD
cd08958 (FR_SDR_e)

128T

substrate binding site
86V, 88A, 127S, 128T, 129A, 132F, 166Y, 193P, 194G, 195V, 208S, 211I, 225N, 229G, 293Y
CDD
cd08958 (FR_SDR_e)

129A

substrate binding site
86V, 88A, 127S, 128T, 129A, 132F, 166Y, 193P, 194G, 195V, 208S, 211I, 225N, 229G, 293Y
CDD
cd08958 (FR_SDR_e)

132F

substrate binding site
86V, 88A, 127S, 128T, 129A, 132F, 166Y, 193P, 194G, 195V, 208S, 211I, 225N, 229G, 293Y
CDD
cd08958 (FR_SDR_e)

166Y

substrate binding site
86V, 88A, 127S, 128T, 129A, 132F, 166Y, 193P, 194G, 195V, 208S, 211I, 225N, 229G, 293Y
CDD
cd08958 (FR_SDR_e)

193P

substrate binding site
86V, 88A, 127S, 128T, 129A, 132F, 166Y, 193P, 194G, 195V, 208S, 211I, 225N, 229G, 293Y
CDD
cd08958 (FR_SDR_e)

194G

substrate binding site
86V, 88A, 127S, 128T, 129A, 132F, 166Y, 193P, 194G, 195V, 208S, 211I, 225N, 229G, 293Y
CDD
cd08958 (FR_SDR_e)

195V

substrate binding site
86V, 88A, 127S, 128T, 129A, 132F, 166Y, 193P, 194G, 195V, 208S, 211I, 225N, 229G, 293Y
CDD
cd08958 (FR_SDR_e)

208S

substrate binding site
86V, 88A, 127S, 128T, 129A, 132F, 166Y, 193P, 194G, 195V, 208S, 211I, 225N, 229G, 293Y
CDD
cd08958 (FR_SDR_e)

211I

substrate binding site
86V, 88A, 127S, 128T, 129A, 132F, 166Y, 193P, 194G, 195V, 208S, 211I, 225N, 229G, 293Y
CDD
cd08958 (FR_SDR_e)

225N

substrate binding site
86V, 88A, 127S, 128T, 129A, 132F, 166Y, 193P, 194G, 195V, 208S, 211I, 225N, 229G, 293Y
CDD
cd08958 (FR_SDR_e)

229G

substrate binding site
86V, 88A, 127S, 128T, 129A, 132F, 166Y, 193P, 194G, 195V, 208S, 211I, 225N, 229G, 293Y
CDD
cd08958 (FR_SDR_e)

293Y

substrate binding site
86V, 88A, 127S, 128T, 129A, 132F, 166Y, 193P, 194G, 195V, 208S, 211I, 225N, 229G, 293Y
CDD
cd08958 (FR_SDR_e)
active site cd08958

102A

active site
102A, 127S, 166Y, 170K
CDD
cd08958 (FR_SDR_e)

127S

active site
102A, 127S, 166Y, 170K
CDD
cd08958 (FR_SDR_e)

166Y

active site
102A, 127S, 166Y, 170K
CDD
cd08958 (FR_SDR_e)

170K

active site
102A, 127S, 166Y, 170K
CDD
cd08958 (FR_SDR_e)

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0003824 catalytic activity

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

Mp8g02830.1

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component