Mp8g07900.1

Protein

Length

324 amino acids

Protein family membership

None predicted.

Homologous superfamilies

Homologous superfamily
1 - 317
NAD(P)-binding domain superfamily (IPR036291)

1 50 100 150 200 250 324

Domains and repeats

Domain
7 - 245
NAD-dependent epimerase/dehydratase (IPR001509)

1 50 100 150 200 250 324

Detailed signature matches

IPR036291

NAD(P)-binding domain superfamily
1. SSF51735 (NAD(P)-bi...)
  
  1 - 317
  
  SUPERFAMILY
  SSF51735 (NAD(P)-binding Rossmann-fold domains)
IPR001509

NAD-dependent epimerase/dehydratase
1. PF01370 (Epimerase)
  
  7 - 245
  
  Pfam
  PF01370 (Epimerase)

no IPR

Unintegrated signatures

G3DSA:3.40.50...

1 - 324

GENE3D
G3DSA:3.40.50.720 (G3DSA:3.40.50.720)
PTHR10366 (NAD DEPE...)

3 - 321

PANTHER
PTHR10366 (NAD DEPENDENT EPIMERASE/DEHYDRATASE)
PTHR10366:SF575 (AL...)

3 - 321

PANTHER
PTHR10366:SF575 (ALCOHOL DEHYDROGENASE-RELATED)
cd08958 (FR_SDR_e)

6 - 300

CDD
cd08958 (FR_SDR_e)

Residue annotation

NADP binding site ...

10G

NADP binding site
10G, 12N, 13G, 14F, 15L, 34V, 35R, 61A, 62N, 63L, 82V, 83A, 84S, 85P, 86V, 125T, 126S, 163Y, 167K, 190P, 191G, 192T, 193M, 205S
CDD
cd08958 (FR_SDR_e)

12N

NADP binding site
10G, 12N, 13G, 14F, 15L, 34V, 35R, 61A, 62N, 63L, 82V, 83A, 84S, 85P, 86V, 125T, 126S, 163Y, 167K, 190P, 191G, 192T, 193M, 205S
CDD
cd08958 (FR_SDR_e)

13G

NADP binding site
10G, 12N, 13G, 14F, 15L, 34V, 35R, 61A, 62N, 63L, 82V, 83A, 84S, 85P, 86V, 125T, 126S, 163Y, 167K, 190P, 191G, 192T, 193M, 205S
CDD
cd08958 (FR_SDR_e)

14F

NADP binding site
10G, 12N, 13G, 14F, 15L, 34V, 35R, 61A, 62N, 63L, 82V, 83A, 84S, 85P, 86V, 125T, 126S, 163Y, 167K, 190P, 191G, 192T, 193M, 205S
CDD
cd08958 (FR_SDR_e)

15L

NADP binding site
10G, 12N, 13G, 14F, 15L, 34V, 35R, 61A, 62N, 63L, 82V, 83A, 84S, 85P, 86V, 125T, 126S, 163Y, 167K, 190P, 191G, 192T, 193M, 205S
CDD
cd08958 (FR_SDR_e)

34V

NADP binding site
10G, 12N, 13G, 14F, 15L, 34V, 35R, 61A, 62N, 63L, 82V, 83A, 84S, 85P, 86V, 125T, 126S, 163Y, 167K, 190P, 191G, 192T, 193M, 205S
CDD
cd08958 (FR_SDR_e)

35R

NADP binding site
10G, 12N, 13G, 14F, 15L, 34V, 35R, 61A, 62N, 63L, 82V, 83A, 84S, 85P, 86V, 125T, 126S, 163Y, 167K, 190P, 191G, 192T, 193M, 205S
CDD
cd08958 (FR_SDR_e)

61A

NADP binding site
10G, 12N, 13G, 14F, 15L, 34V, 35R, 61A, 62N, 63L, 82V, 83A, 84S, 85P, 86V, 125T, 126S, 163Y, 167K, 190P, 191G, 192T, 193M, 205S
CDD
cd08958 (FR_SDR_e)

62N

NADP binding site
10G, 12N, 13G, 14F, 15L, 34V, 35R, 61A, 62N, 63L, 82V, 83A, 84S, 85P, 86V, 125T, 126S, 163Y, 167K, 190P, 191G, 192T, 193M, 205S
CDD
cd08958 (FR_SDR_e)

63L

NADP binding site
10G, 12N, 13G, 14F, 15L, 34V, 35R, 61A, 62N, 63L, 82V, 83A, 84S, 85P, 86V, 125T, 126S, 163Y, 167K, 190P, 191G, 192T, 193M, 205S
CDD
cd08958 (FR_SDR_e)

82V

NADP binding site
10G, 12N, 13G, 14F, 15L, 34V, 35R, 61A, 62N, 63L, 82V, 83A, 84S, 85P, 86V, 125T, 126S, 163Y, 167K, 190P, 191G, 192T, 193M, 205S
CDD
cd08958 (FR_SDR_e)

83A

NADP binding site
10G, 12N, 13G, 14F, 15L, 34V, 35R, 61A, 62N, 63L, 82V, 83A, 84S, 85P, 86V, 125T, 126S, 163Y, 167K, 190P, 191G, 192T, 193M, 205S
CDD
cd08958 (FR_SDR_e)

84S

NADP binding site
10G, 12N, 13G, 14F, 15L, 34V, 35R, 61A, 62N, 63L, 82V, 83A, 84S, 85P, 86V, 125T, 126S, 163Y, 167K, 190P, 191G, 192T, 193M, 205S
CDD
cd08958 (FR_SDR_e)

85P

NADP binding site
10G, 12N, 13G, 14F, 15L, 34V, 35R, 61A, 62N, 63L, 82V, 83A, 84S, 85P, 86V, 125T, 126S, 163Y, 167K, 190P, 191G, 192T, 193M, 205S
CDD
cd08958 (FR_SDR_e)

86V

NADP binding site
10G, 12N, 13G, 14F, 15L, 34V, 35R, 61A, 62N, 63L, 82V, 83A, 84S, 85P, 86V, 125T, 126S, 163Y, 167K, 190P, 191G, 192T, 193M, 205S
CDD
cd08958 (FR_SDR_e)

125T

NADP binding site
10G, 12N, 13G, 14F, 15L, 34V, 35R, 61A, 62N, 63L, 82V, 83A, 84S, 85P, 86V, 125T, 126S, 163Y, 167K, 190P, 191G, 192T, 193M, 205S
CDD
cd08958 (FR_SDR_e)

126S

NADP binding site
10G, 12N, 13G, 14F, 15L, 34V, 35R, 61A, 62N, 63L, 82V, 83A, 84S, 85P, 86V, 125T, 126S, 163Y, 167K, 190P, 191G, 192T, 193M, 205S
CDD
cd08958 (FR_SDR_e)

163Y

NADP binding site
10G, 12N, 13G, 14F, 15L, 34V, 35R, 61A, 62N, 63L, 82V, 83A, 84S, 85P, 86V, 125T, 126S, 163Y, 167K, 190P, 191G, 192T, 193M, 205S
CDD
cd08958 (FR_SDR_e)

167K

NADP binding site
10G, 12N, 13G, 14F, 15L, 34V, 35R, 61A, 62N, 63L, 82V, 83A, 84S, 85P, 86V, 125T, 126S, 163Y, 167K, 190P, 191G, 192T, 193M, 205S
CDD
cd08958 (FR_SDR_e)

190P

NADP binding site
10G, 12N, 13G, 14F, 15L, 34V, 35R, 61A, 62N, 63L, 82V, 83A, 84S, 85P, 86V, 125T, 126S, 163Y, 167K, 190P, 191G, 192T, 193M, 205S
CDD
cd08958 (FR_SDR_e)

191G

NADP binding site
10G, 12N, 13G, 14F, 15L, 34V, 35R, 61A, 62N, 63L, 82V, 83A, 84S, 85P, 86V, 125T, 126S, 163Y, 167K, 190P, 191G, 192T, 193M, 205S
CDD
cd08958 (FR_SDR_e)

192T

NADP binding site
10G, 12N, 13G, 14F, 15L, 34V, 35R, 61A, 62N, 63L, 82V, 83A, 84S, 85P, 86V, 125T, 126S, 163Y, 167K, 190P, 191G, 192T, 193M, 205S
CDD
cd08958 (FR_SDR_e)

193M

NADP binding site
10G, 12N, 13G, 14F, 15L, 34V, 35R, 61A, 62N, 63L, 82V, 83A, 84S, 85P, 86V, 125T, 126S, 163Y, 167K, 190P, 191G, 192T, 193M, 205S
CDD
cd08958 (FR_SDR_e)

205S

NADP binding site
10G, 12N, 13G, 14F, 15L, 34V, 35R, 61A, 62N, 63L, 82V, 83A, 84S, 85P, 86V, 125T, 126S, 163Y, 167K, 190P, 191G, 192T, 193M, 205S
CDD
cd08958 (FR_SDR_e)
substrate binding ...

86V

substrate binding site
86V, 88S, 127S, 128V, 129S, 132F, 163Y, 190P, 191G, 192T, 205S, 208I, 222N, 226G, 290Y
CDD
cd08958 (FR_SDR_e)

88S

substrate binding site
86V, 88S, 127S, 128V, 129S, 132F, 163Y, 190P, 191G, 192T, 205S, 208I, 222N, 226G, 290Y
CDD
cd08958 (FR_SDR_e)

127S

substrate binding site
86V, 88S, 127S, 128V, 129S, 132F, 163Y, 190P, 191G, 192T, 205S, 208I, 222N, 226G, 290Y
CDD
cd08958 (FR_SDR_e)

128V

substrate binding site
86V, 88S, 127S, 128V, 129S, 132F, 163Y, 190P, 191G, 192T, 205S, 208I, 222N, 226G, 290Y
CDD
cd08958 (FR_SDR_e)

129S

substrate binding site
86V, 88S, 127S, 128V, 129S, 132F, 163Y, 190P, 191G, 192T, 205S, 208I, 222N, 226G, 290Y
CDD
cd08958 (FR_SDR_e)

132F

substrate binding site
86V, 88S, 127S, 128V, 129S, 132F, 163Y, 190P, 191G, 192T, 205S, 208I, 222N, 226G, 290Y
CDD
cd08958 (FR_SDR_e)

163Y

substrate binding site
86V, 88S, 127S, 128V, 129S, 132F, 163Y, 190P, 191G, 192T, 205S, 208I, 222N, 226G, 290Y
CDD
cd08958 (FR_SDR_e)

190P

substrate binding site
86V, 88S, 127S, 128V, 129S, 132F, 163Y, 190P, 191G, 192T, 205S, 208I, 222N, 226G, 290Y
CDD
cd08958 (FR_SDR_e)

191G

substrate binding site
86V, 88S, 127S, 128V, 129S, 132F, 163Y, 190P, 191G, 192T, 205S, 208I, 222N, 226G, 290Y
CDD
cd08958 (FR_SDR_e)

192T

substrate binding site
86V, 88S, 127S, 128V, 129S, 132F, 163Y, 190P, 191G, 192T, 205S, 208I, 222N, 226G, 290Y
CDD
cd08958 (FR_SDR_e)

205S

substrate binding site
86V, 88S, 127S, 128V, 129S, 132F, 163Y, 190P, 191G, 192T, 205S, 208I, 222N, 226G, 290Y
CDD
cd08958 (FR_SDR_e)

208I

substrate binding site
86V, 88S, 127S, 128V, 129S, 132F, 163Y, 190P, 191G, 192T, 205S, 208I, 222N, 226G, 290Y
CDD
cd08958 (FR_SDR_e)

222N

substrate binding site
86V, 88S, 127S, 128V, 129S, 132F, 163Y, 190P, 191G, 192T, 205S, 208I, 222N, 226G, 290Y
CDD
cd08958 (FR_SDR_e)

226G

substrate binding site
86V, 88S, 127S, 128V, 129S, 132F, 163Y, 190P, 191G, 192T, 205S, 208I, 222N, 226G, 290Y
CDD
cd08958 (FR_SDR_e)

290Y

substrate binding site
86V, 88S, 127S, 128V, 129S, 132F, 163Y, 190P, 191G, 192T, 205S, 208I, 222N, 226G, 290Y
CDD
cd08958 (FR_SDR_e)
active site cd08958

102A

active site
102A, 127S, 163Y, 167K
CDD
cd08958 (FR_SDR_e)

127S

active site
102A, 127S, 163Y, 167K
CDD
cd08958 (FR_SDR_e)

163Y

active site
102A, 127S, 163Y, 167K
CDD
cd08958 (FR_SDR_e)

167K

active site
102A, 127S, 163Y, 167K
CDD
cd08958 (FR_SDR_e)

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0003824 catalytic activity

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

Mp8g07900.1

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component