Mp8g05510.1

Protein

Length

3,137 amino acids

Protein family membership

Serine/threonine-protein kinase ATM, plant (IPR038980)

Homologous superfamilies

Homologous superfamily
913 - 1,755
Armadillo-type fold (IPR016024)
2,710 - 3,070
Protein kinase-like domain superfamily (IPR011009)
Homologous superfamily
2,911 - 3,098
Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily (IPR036940)

1 500 1000 1500 2000 2500 3137

Domains and repeats

Domain
11 - 158
Telomere-length maintenance and DNA damage repair (IPR021668)
2,776 - 3,137
Phosphatidylinositol 3-/4-kinase, catalytic domain (IPR000403)
ATM, catalytic domain (IPR044107)
Domain
1,982 - 2,673
PIK-related kinase (IPR014009)
PIK-related kinase, FAT (IPR003151)
3,105 - 3,137
FATC domain (IPR003152)

1 500 1000 1500 2000 2500 3137

Detailed signature matches

IPR016024

Armadillo-type fold
1. SSF48371 (ARM repeat)
  
  1,241 - 1,353
  
  SUPERFAMILY
  SSF48371 (ARM repeat)
  
  1,381 - 1,526
  
  SUPERFAMILY
  SSF48371 (ARM repeat)
  
  913 - 996
  
  SUPERFAMILY
  SSF48371 (ARM repeat)
  
  1,059 - 1,126
  
  SUPERFAMILY
  SSF48371 (ARM repeat)
  
  1,551 - 1,755
  
  SUPERFAMILY
  SSF48371 (ARM repeat)
IPR011009

Protein kinase-like domain superfamily
1. SSF56112 (Protein k...)
  
  2,917 - 3,070
  
  SUPERFAMILY
  SSF56112 (Protein kinase-like (PK-like))
  
  2,710 - 2,883
  
  SUPERFAMILY
  SSF56112 (Protein kinase-like (PK-like))
IPR036940

Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily
1. G3DSA:1.10.10...
  
  2,911 - 3,098
  
  GENE3D
  G3DSA:1.10.1070.11 (G3DSA:1.10.1070.11)
IPR038980

Serine/threonine-protein kinase ATM, plant
1. PTHR37079 (SERINE/T...)
  
  23 - 3,137
  
  PANTHER
  PTHR37079 (SERINE/THREONINE-PROTEIN KINASE ATM)
IPR021668

Telomere-length maintenance and DNA damage repair
1. PF11640 (TAN)
  
  11 - 158
  
  Pfam
  PF11640 (TAN)
IPR014009

PIK-related kinase
1. PS51189 (FAT)
  
  1,982 - 2,673
  
  PROSITE profiles
  PS51189 (FAT)
IPR003151

PIK-related kinase, FAT
1. PF02259 (FAT)
  
  2,158 - 2,593
  
  Pfam
  PF02259 (FAT)
IPR000403

Phosphatidylinositol 3-/4-kinase, catalytic domain
1. PS50290 (PI3_4_KINA...)
  
  2,805 - 3,137
  
  PROSITE profiles
  PS50290 (PI3_4_KINASE_3)
2. SM00146 (pi3k_hr1_6)
  
  2,806 - 3,119
  
  SMART
  SM00146 (pi3k_hr1_6)
3. PF00454 (PI3_PI4_ki...)
  
  2,812 - 3,052
  
  Pfam
  PF00454 (PI3_PI4_kinase)
IPR044107

ATM, catalytic domain
1. cd05171 (PIKKc_ATM)
  
  2,776 - 3,053
  
  CDD
  cd05171 (PIKKc_ATM)
IPR003152

FATC domain
1. SM01343 (FATC_2)
  
  3,105 - 3,137
  
  SMART
  SM01343 (FATC_2)
2. PF02260 (FATC)
  
  3,108 - 3,136
  
  Pfam
  PF02260 (FATC)
3. PS51190 (FATC)
  
  3,105 - 3,137
  
  PROSITE profiles
  PS51190 (FATC)
IPR018936

Phosphatidylinositol 3/4-kinase, conserved site
1. PS00916 (PI3_4_KINA...)
  
  2,946 - 2,966
  
  PROSITE patterns
  PS00916 (PI3_4_KINASE_2)
2. PS00915 (PI3_4_KINA...)
  
  2,809 - 2,824
  
  PROSITE patterns
  PS00915 (PI3_4_KINASE_1)

no IPR

Unintegrated signatures

G3DSA:3.30.10...

2,702 - 2,865

GENE3D
G3DSA:3.30.1010.10 (G3DSA:3.30.1010.10)
PTHR37079:SF4 (SERI...)

23 - 3,137

PANTHER
PTHR37079:SF4 (SERINE/THREONINE-PROTEIN KINASE ATM)

Other features

mobidb-lite (disord...)

1,921 - 1,953

MobiDB Lite
mobidb-lite (disorder_prediction)
mobidb-lite (Polyam...)

1,921 - 1,938

MobiDB Lite
mobidb-lite (disorder_prediction)
Feature: Polyampholyte
mobidb-lite (Polar)

1,939 - 1,953

MobiDB Lite
mobidb-lite (disorder_prediction)
Feature: Polar

Residue annotation

ATP binding site c...

2,786M

ATP binding site
2,786M, 2,788G, 2,789I, 2,790N, 2,792P, 2,808L, 2,810K, 2,814D, 2,849Y, 2,861L, 2,862E, 2,863W, 2,864V, 2,869P, 2,966N, 2,968L, 2,979I, 2,980D
CDD
cd05171 (PIKKc_ATM)

2,788G

ATP binding site
2,786M, 2,788G, 2,789I, 2,790N, 2,792P, 2,808L, 2,810K, 2,814D, 2,849Y, 2,861L, 2,862E, 2,863W, 2,864V, 2,869P, 2,966N, 2,968L, 2,979I, 2,980D
CDD
cd05171 (PIKKc_ATM)

2,789I

ATP binding site
2,786M, 2,788G, 2,789I, 2,790N, 2,792P, 2,808L, 2,810K, 2,814D, 2,849Y, 2,861L, 2,862E, 2,863W, 2,864V, 2,869P, 2,966N, 2,968L, 2,979I, 2,980D
CDD
cd05171 (PIKKc_ATM)

2,790N

ATP binding site
2,786M, 2,788G, 2,789I, 2,790N, 2,792P, 2,808L, 2,810K, 2,814D, 2,849Y, 2,861L, 2,862E, 2,863W, 2,864V, 2,869P, 2,966N, 2,968L, 2,979I, 2,980D
CDD
cd05171 (PIKKc_ATM)

2,792P

ATP binding site
2,786M, 2,788G, 2,789I, 2,790N, 2,792P, 2,808L, 2,810K, 2,814D, 2,849Y, 2,861L, 2,862E, 2,863W, 2,864V, 2,869P, 2,966N, 2,968L, 2,979I, 2,980D
CDD
cd05171 (PIKKc_ATM)

2,808L

ATP binding site
2,786M, 2,788G, 2,789I, 2,790N, 2,792P, 2,808L, 2,810K, 2,814D, 2,849Y, 2,861L, 2,862E, 2,863W, 2,864V, 2,869P, 2,966N, 2,968L, 2,979I, 2,980D
CDD
cd05171 (PIKKc_ATM)

2,810K

ATP binding site
2,786M, 2,788G, 2,789I, 2,790N, 2,792P, 2,808L, 2,810K, 2,814D, 2,849Y, 2,861L, 2,862E, 2,863W, 2,864V, 2,869P, 2,966N, 2,968L, 2,979I, 2,980D
CDD
cd05171 (PIKKc_ATM)

2,814D

ATP binding site
2,786M, 2,788G, 2,789I, 2,790N, 2,792P, 2,808L, 2,810K, 2,814D, 2,849Y, 2,861L, 2,862E, 2,863W, 2,864V, 2,869P, 2,966N, 2,968L, 2,979I, 2,980D
CDD
cd05171 (PIKKc_ATM)

2,849Y

ATP binding site
2,786M, 2,788G, 2,789I, 2,790N, 2,792P, 2,808L, 2,810K, 2,814D, 2,849Y, 2,861L, 2,862E, 2,863W, 2,864V, 2,869P, 2,966N, 2,968L, 2,979I, 2,980D
CDD
cd05171 (PIKKc_ATM)

2,861L

ATP binding site
2,786M, 2,788G, 2,789I, 2,790N, 2,792P, 2,808L, 2,810K, 2,814D, 2,849Y, 2,861L, 2,862E, 2,863W, 2,864V, 2,869P, 2,966N, 2,968L, 2,979I, 2,980D
CDD
cd05171 (PIKKc_ATM)

2,862E

ATP binding site
2,786M, 2,788G, 2,789I, 2,790N, 2,792P, 2,808L, 2,810K, 2,814D, 2,849Y, 2,861L, 2,862E, 2,863W, 2,864V, 2,869P, 2,966N, 2,968L, 2,979I, 2,980D
CDD
cd05171 (PIKKc_ATM)

2,863W

ATP binding site
2,786M, 2,788G, 2,789I, 2,790N, 2,792P, 2,808L, 2,810K, 2,814D, 2,849Y, 2,861L, 2,862E, 2,863W, 2,864V, 2,869P, 2,966N, 2,968L, 2,979I, 2,980D
CDD
cd05171 (PIKKc_ATM)

2,864V

ATP binding site
2,786M, 2,788G, 2,789I, 2,790N, 2,792P, 2,808L, 2,810K, 2,814D, 2,849Y, 2,861L, 2,862E, 2,863W, 2,864V, 2,869P, 2,966N, 2,968L, 2,979I, 2,980D
CDD
cd05171 (PIKKc_ATM)

2,869P

ATP binding site
2,786M, 2,788G, 2,789I, 2,790N, 2,792P, 2,808L, 2,810K, 2,814D, 2,849Y, 2,861L, 2,862E, 2,863W, 2,864V, 2,869P, 2,966N, 2,968L, 2,979I, 2,980D
CDD
cd05171 (PIKKc_ATM)

2,966N

ATP binding site
2,786M, 2,788G, 2,789I, 2,790N, 2,792P, 2,808L, 2,810K, 2,814D, 2,849Y, 2,861L, 2,862E, 2,863W, 2,864V, 2,869P, 2,966N, 2,968L, 2,979I, 2,980D
CDD
cd05171 (PIKKc_ATM)

2,968L

ATP binding site
2,786M, 2,788G, 2,789I, 2,790N, 2,792P, 2,808L, 2,810K, 2,814D, 2,849Y, 2,861L, 2,862E, 2,863W, 2,864V, 2,869P, 2,966N, 2,968L, 2,979I, 2,980D
CDD
cd05171 (PIKKc_ATM)

2,979I

ATP binding site
2,786M, 2,788G, 2,789I, 2,790N, 2,792P, 2,808L, 2,810K, 2,814D, 2,849Y, 2,861L, 2,862E, 2,863W, 2,864V, 2,869P, 2,966N, 2,968L, 2,979I, 2,980D
CDD
cd05171 (PIKKc_ATM)

2,980D

ATP binding site
2,786M, 2,788G, 2,789I, 2,790N, 2,792P, 2,808L, 2,810K, 2,814D, 2,849Y, 2,861L, 2,862E, 2,863W, 2,864V, 2,869P, 2,966N, 2,968L, 2,979I, 2,980D
CDD
cd05171 (PIKKc_ATM)
catalytic loop cd0...

2,958G

catalytic loop
2,958G, 2,959L, 2,960G, 2,961D, 2,962R, 2,963H, 2,964S, 2,965V, 2,966N
CDD
cd05171 (PIKKc_ATM)

2,959L

catalytic loop
2,958G, 2,959L, 2,960G, 2,961D, 2,962R, 2,963H, 2,964S, 2,965V, 2,966N
CDD
cd05171 (PIKKc_ATM)

2,960G

catalytic loop
2,958G, 2,959L, 2,960G, 2,961D, 2,962R, 2,963H, 2,964S, 2,965V, 2,966N
CDD
cd05171 (PIKKc_ATM)

2,961D

catalytic loop
2,958G, 2,959L, 2,960G, 2,961D, 2,962R, 2,963H, 2,964S, 2,965V, 2,966N
CDD
cd05171 (PIKKc_ATM)

2,962R

catalytic loop
2,958G, 2,959L, 2,960G, 2,961D, 2,962R, 2,963H, 2,964S, 2,965V, 2,966N
CDD
cd05171 (PIKKc_ATM)

2,963H

catalytic loop
2,958G, 2,959L, 2,960G, 2,961D, 2,962R, 2,963H, 2,964S, 2,965V, 2,966N
CDD
cd05171 (PIKKc_ATM)

2,964S

catalytic loop
2,958G, 2,959L, 2,960G, 2,961D, 2,962R, 2,963H, 2,964S, 2,965V, 2,966N
CDD
cd05171 (PIKKc_ATM)

2,965V

catalytic loop
2,958G, 2,959L, 2,960G, 2,961D, 2,962R, 2,963H, 2,964S, 2,965V, 2,966N
CDD
cd05171 (PIKKc_ATM)

2,966N

catalytic loop
2,958G, 2,959L, 2,960G, 2,961D, 2,962R, 2,963H, 2,964S, 2,965V, 2,966N
CDD
cd05171 (PIKKc_ATM)
activation loop (A...

2,980D

activation loop (A-loop)
2,980D, 2,981L, 2,982G, 2,983V, 2,984A, 2,985F, 2,986E, 2,987Q, 2,988G, 2,989L, 2,990M, 2,991L, 2,992K, 2,993T, 2,994P, 2,995E, 2,996R, 2,997V, 2,998P, 2,999F, 3,000R, 3,001L, 3,002T
CDD
cd05171 (PIKKc_ATM)

2,981L

activation loop (A-loop)
2,980D, 2,981L, 2,982G, 2,983V, 2,984A, 2,985F, 2,986E, 2,987Q, 2,988G, 2,989L, 2,990M, 2,991L, 2,992K, 2,993T, 2,994P, 2,995E, 2,996R, 2,997V, 2,998P, 2,999F, 3,000R, 3,001L, 3,002T
CDD
cd05171 (PIKKc_ATM)

2,982G

activation loop (A-loop)
2,980D, 2,981L, 2,982G, 2,983V, 2,984A, 2,985F, 2,986E, 2,987Q, 2,988G, 2,989L, 2,990M, 2,991L, 2,992K, 2,993T, 2,994P, 2,995E, 2,996R, 2,997V, 2,998P, 2,999F, 3,000R, 3,001L, 3,002T
CDD
cd05171 (PIKKc_ATM)

2,983V

activation loop (A-loop)
2,980D, 2,981L, 2,982G, 2,983V, 2,984A, 2,985F, 2,986E, 2,987Q, 2,988G, 2,989L, 2,990M, 2,991L, 2,992K, 2,993T, 2,994P, 2,995E, 2,996R, 2,997V, 2,998P, 2,999F, 3,000R, 3,001L, 3,002T
CDD
cd05171 (PIKKc_ATM)

2,984A

activation loop (A-loop)
2,980D, 2,981L, 2,982G, 2,983V, 2,984A, 2,985F, 2,986E, 2,987Q, 2,988G, 2,989L, 2,990M, 2,991L, 2,992K, 2,993T, 2,994P, 2,995E, 2,996R, 2,997V, 2,998P, 2,999F, 3,000R, 3,001L, 3,002T
CDD
cd05171 (PIKKc_ATM)

2,985F

activation loop (A-loop)
2,980D, 2,981L, 2,982G, 2,983V, 2,984A, 2,985F, 2,986E, 2,987Q, 2,988G, 2,989L, 2,990M, 2,991L, 2,992K, 2,993T, 2,994P, 2,995E, 2,996R, 2,997V, 2,998P, 2,999F, 3,000R, 3,001L, 3,002T
CDD
cd05171 (PIKKc_ATM)

2,986E

activation loop (A-loop)
2,980D, 2,981L, 2,982G, 2,983V, 2,984A, 2,985F, 2,986E, 2,987Q, 2,988G, 2,989L, 2,990M, 2,991L, 2,992K, 2,993T, 2,994P, 2,995E, 2,996R, 2,997V, 2,998P, 2,999F, 3,000R, 3,001L, 3,002T
CDD
cd05171 (PIKKc_ATM)

2,987Q

activation loop (A-loop)
2,980D, 2,981L, 2,982G, 2,983V, 2,984A, 2,985F, 2,986E, 2,987Q, 2,988G, 2,989L, 2,990M, 2,991L, 2,992K, 2,993T, 2,994P, 2,995E, 2,996R, 2,997V, 2,998P, 2,999F, 3,000R, 3,001L, 3,002T
CDD
cd05171 (PIKKc_ATM)

2,988G

activation loop (A-loop)
2,980D, 2,981L, 2,982G, 2,983V, 2,984A, 2,985F, 2,986E, 2,987Q, 2,988G, 2,989L, 2,990M, 2,991L, 2,992K, 2,993T, 2,994P, 2,995E, 2,996R, 2,997V, 2,998P, 2,999F, 3,000R, 3,001L, 3,002T
CDD
cd05171 (PIKKc_ATM)

2,989L

activation loop (A-loop)
2,980D, 2,981L, 2,982G, 2,983V, 2,984A, 2,985F, 2,986E, 2,987Q, 2,988G, 2,989L, 2,990M, 2,991L, 2,992K, 2,993T, 2,994P, 2,995E, 2,996R, 2,997V, 2,998P, 2,999F, 3,000R, 3,001L, 3,002T
CDD
cd05171 (PIKKc_ATM)

2,990M

activation loop (A-loop)
2,980D, 2,981L, 2,982G, 2,983V, 2,984A, 2,985F, 2,986E, 2,987Q, 2,988G, 2,989L, 2,990M, 2,991L, 2,992K, 2,993T, 2,994P, 2,995E, 2,996R, 2,997V, 2,998P, 2,999F, 3,000R, 3,001L, 3,002T
CDD
cd05171 (PIKKc_ATM)

2,991L

activation loop (A-loop)
2,980D, 2,981L, 2,982G, 2,983V, 2,984A, 2,985F, 2,986E, 2,987Q, 2,988G, 2,989L, 2,990M, 2,991L, 2,992K, 2,993T, 2,994P, 2,995E, 2,996R, 2,997V, 2,998P, 2,999F, 3,000R, 3,001L, 3,002T
CDD
cd05171 (PIKKc_ATM)

2,992K

activation loop (A-loop)
2,980D, 2,981L, 2,982G, 2,983V, 2,984A, 2,985F, 2,986E, 2,987Q, 2,988G, 2,989L, 2,990M, 2,991L, 2,992K, 2,993T, 2,994P, 2,995E, 2,996R, 2,997V, 2,998P, 2,999F, 3,000R, 3,001L, 3,002T
CDD
cd05171 (PIKKc_ATM)

2,993T

activation loop (A-loop)
2,980D, 2,981L, 2,982G, 2,983V, 2,984A, 2,985F, 2,986E, 2,987Q, 2,988G, 2,989L, 2,990M, 2,991L, 2,992K, 2,993T, 2,994P, 2,995E, 2,996R, 2,997V, 2,998P, 2,999F, 3,000R, 3,001L, 3,002T
CDD
cd05171 (PIKKc_ATM)

2,994P

activation loop (A-loop)
2,980D, 2,981L, 2,982G, 2,983V, 2,984A, 2,985F, 2,986E, 2,987Q, 2,988G, 2,989L, 2,990M, 2,991L, 2,992K, 2,993T, 2,994P, 2,995E, 2,996R, 2,997V, 2,998P, 2,999F, 3,000R, 3,001L, 3,002T
CDD
cd05171 (PIKKc_ATM)

2,995E

activation loop (A-loop)
2,980D, 2,981L, 2,982G, 2,983V, 2,984A, 2,985F, 2,986E, 2,987Q, 2,988G, 2,989L, 2,990M, 2,991L, 2,992K, 2,993T, 2,994P, 2,995E, 2,996R, 2,997V, 2,998P, 2,999F, 3,000R, 3,001L, 3,002T
CDD
cd05171 (PIKKc_ATM)

2,996R

activation loop (A-loop)
2,980D, 2,981L, 2,982G, 2,983V, 2,984A, 2,985F, 2,986E, 2,987Q, 2,988G, 2,989L, 2,990M, 2,991L, 2,992K, 2,993T, 2,994P, 2,995E, 2,996R, 2,997V, 2,998P, 2,999F, 3,000R, 3,001L, 3,002T
CDD
cd05171 (PIKKc_ATM)

2,997V

activation loop (A-loop)
2,980D, 2,981L, 2,982G, 2,983V, 2,984A, 2,985F, 2,986E, 2,987Q, 2,988G, 2,989L, 2,990M, 2,991L, 2,992K, 2,993T, 2,994P, 2,995E, 2,996R, 2,997V, 2,998P, 2,999F, 3,000R, 3,001L, 3,002T
CDD
cd05171 (PIKKc_ATM)

2,998P

activation loop (A-loop)
2,980D, 2,981L, 2,982G, 2,983V, 2,984A, 2,985F, 2,986E, 2,987Q, 2,988G, 2,989L, 2,990M, 2,991L, 2,992K, 2,993T, 2,994P, 2,995E, 2,996R, 2,997V, 2,998P, 2,999F, 3,000R, 3,001L, 3,002T
CDD
cd05171 (PIKKc_ATM)

2,999F

activation loop (A-loop)
2,980D, 2,981L, 2,982G, 2,983V, 2,984A, 2,985F, 2,986E, 2,987Q, 2,988G, 2,989L, 2,990M, 2,991L, 2,992K, 2,993T, 2,994P, 2,995E, 2,996R, 2,997V, 2,998P, 2,999F, 3,000R, 3,001L, 3,002T
CDD
cd05171 (PIKKc_ATM)

3,000R

activation loop (A-loop)
2,980D, 2,981L, 2,982G, 2,983V, 2,984A, 2,985F, 2,986E, 2,987Q, 2,988G, 2,989L, 2,990M, 2,991L, 2,992K, 2,993T, 2,994P, 2,995E, 2,996R, 2,997V, 2,998P, 2,999F, 3,000R, 3,001L, 3,002T
CDD
cd05171 (PIKKc_ATM)

3,001L

activation loop (A-loop)
2,980D, 2,981L, 2,982G, 2,983V, 2,984A, 2,985F, 2,986E, 2,987Q, 2,988G, 2,989L, 2,990M, 2,991L, 2,992K, 2,993T, 2,994P, 2,995E, 2,996R, 2,997V, 2,998P, 2,999F, 3,000R, 3,001L, 3,002T
CDD
cd05171 (PIKKc_ATM)

3,002T

activation loop (A-loop)
2,980D, 2,981L, 2,982G, 2,983V, 2,984A, 2,985F, 2,986E, 2,987Q, 2,988G, 2,989L, 2,990M, 2,991L, 2,992K, 2,993T, 2,994P, 2,995E, 2,996R, 2,997V, 2,998P, 2,999F, 3,000R, 3,001L, 3,002T
CDD
cd05171 (PIKKc_ATM)

GO term prediction

Biological Process

GO:0006281 DNA repair
GO:0006974 cellular response to DNA damage stimulus

Molecular Function

GO:0004674 protein serine/threonine kinase activity
GO:0005515 protein binding
GO:0016301 kinase activity

Cellular Component

None predicted.

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Entry type

Status

Per-residue features