Mp1g25450.1

Protein

Length

1,247 amino acids

Protein family membership

P-type ATPase (IPR001757)
- P-type ATPase, subfamily V (IPR006544)

Homologous superfamilies

Homologous superfamily
188 - 274
P-type ATPase, transmembrane domain superfamily (IPR023298)
405 - 503
P-type ATPase, transmembrane domain superfamily (IPR023298)
506 - 699
P-type ATPase, cytoplasmic domain N (IPR023299)
1,007 - 1,223
P-type ATPase, transmembrane domain superfamily (IPR023298)
Homologous superfamily
276 - 408
P-type ATPase, A domain superfamily (IPR008250)
504 - 520
HAD-like superfamily (IPR036412)
646 - 748
HAD-like superfamily (IPR036412)
803 - 862
HAD-like superfamily (IPR036412)
Homologous superfamily
691 - 869
HAD superfamily (IPR023214)

1 200 400 600 800 1000 1247

Domains and repeats

None predicted.

Detailed signature matches

IPR023298

P-type ATPase, transmembrane domain superfamily
1. SSF81665 (Calcium A...)
  
  188 - 274
  
  SUPERFAMILY
  SSF81665 (Calcium ATPase, transmembrane domain M)
  Model: 0049473
  
  405 - 503
  
  SUPERFAMILY
  SSF81665 (Calcium ATPase, transmembrane domain M)
  Model: 0049473
  
  1,007 - 1,223
  
  SUPERFAMILY
  SSF81665 (Calcium ATPase, transmembrane domain M)
  Model: 0049473
IPR008250

P-type ATPase, A domain superfamily
1. SSF81653 (Calcium A...)
  
  276 - 408
  
  SUPERFAMILY
  SSF81653 (Calcium ATPase, transduction domain A)
  Model: 0049471
IPR036412

HAD-like superfamily
1. SSF56784 (HAD-like)
  
  646 - 748
  
  SUPERFAMILY
  SSF56784 (HAD-like)
  Model: 0049197
  
  504 - 520
  
  SUPERFAMILY
  SSF56784 (HAD-like)
  Model: 0049197
  
  803 - 862
  
  SUPERFAMILY
  SSF56784 (HAD-like)
  Model: 0049197
IPR023299

P-type ATPase, cytoplasmic domain N
1. SSF81660 (Metal cat...)
  
  515 - 699
  
  SUPERFAMILY
  SSF81660 (Metal cation-transporting ATPase, ATP-binding domain N)
  Model: 0042598
2. G3DSA:3.40.11...
  
  506 - 690
  
  GENE3D
  G3DSA:3.40.1110.10 (G3DSA:3.40.1110.10)
  Model: 3ar4A04
IPR023214

HAD superfamily
1. G3DSA:3.40.50...
  
  691 - 869
  
  GENE3D
  G3DSA:3.40.50.1000 (G3DSA:3.40.50.1000)
  Model: 2zxeA03
IPR001757

P-type ATPase
1. TIGR01494
  
  424 - 542
  
  TIGRFAMs
  TIGR01494 (TIGR01494)
IPR006544

P-type ATPase, subfamily V
1. TIGR01657
  
  37 - 1,196
  
  TIGRFAMs
  TIGR01657 (TIGR01657)
IPR018303

P-type ATPase, phosphorylation site
1. PS00154 (ATPASE_E1_E2)
  
  511 - 517
  
  PROSITE patterns
  PS00154 (ATPASE_E1_E2)

no IPR

Unintegrated signatures

G3DSA:2.70.15...

253 - 409

GENE3D
G3DSA:2.70.150.10 (G3DSA:2.70.150.10)
Model: 2zbdA01
PF00122 (E1-E2_ATPase)

276 - 489

Pfam
PF00122 (E1-E2_ATPase)
PF00702 (Hydrolase)

505 - 762

Pfam
PF00702 (Hydrolase)
PR00119 (CATATPASE)

711 - 721

PRINTS
PR00119 (CATATPASE)

509 - 523

PRINTS
PR00119 (CATATPASE)

833 - 852

PRINTS
PR00119 (CATATPASE)

329 - 343

PRINTS
PR00119 (CATATPASE)
PS01229 (COF_2)

833 - 855

PROSITE patterns
PS01229 (COF_2)
SFLDF00027 (p-type_...)

490 - 1,009

SFLD
SFLDF00027 (p-type_atpase)
SFLDS00003 (Haloaci...)

490 - 1,009

SFLD
SFLDS00003 (Haloacid_Dehalogenase)
cd07543 (P-type_ATP...)

195 - 1,161

CDD
cd07543 (P-type_ATPase_cation)

Other features

mobidb-lite (disord...)

1,227 - 1,247

MobiDB Lite
mobidb-lite (disorder_prediction)

863 - 898

MobiDB Lite
mobidb-lite (disorder_prediction)

911 - 954

MobiDB Lite
mobidb-lite (disorder_prediction)
mobidb-lite (Polar)

926 - 945

MobiDB Lite
mobidb-lite (disorder_prediction)
Feature: Polar

863 - 893

MobiDB Lite
mobidb-lite (disorder_prediction)
Feature: Polar

Residue annotation

phosphorylation si...

511D

phosphorylation site
511D
CDD
cd07543 (P-type_ATPase_cation)
SFLDF00027

511D

nucleophile: attacks gamma phosphate moiety of ATP to form covalent intermediate, Mg2+ ligand
511D
SFLD
SFLDF00027 (p-type_atpase)
P-type ATPase sign...

511D

P-type ATPase signature motif
511D, 512K, 513T, 514G, 515T, 516L, 517T
CDD
cd07543 (P-type_ATPase_cation)

512K

P-type ATPase signature motif
511D, 512K, 513T, 514G, 515T, 516L, 517T
CDD
cd07543 (P-type_ATPase_cation)

513T

P-type ATPase signature motif
511D, 512K, 513T, 514G, 515T, 516L, 517T
CDD
cd07543 (P-type_ATPase_cation)

514G

P-type ATPase signature motif
511D, 512K, 513T, 514G, 515T, 516L, 517T
CDD
cd07543 (P-type_ATPase_cation)

515T

P-type ATPase signature motif
511D, 512K, 513T, 514G, 515T, 516L, 517T
CDD
cd07543 (P-type_ATPase_cation)

516L

P-type ATPase signature motif
511D, 512K, 513T, 514G, 515T, 516L, 517T
CDD
cd07543 (P-type_ATPase_cation)

517T

P-type ATPase signature motif
511D, 512K, 513T, 514G, 515T, 516L, 517T
CDD
cd07543 (P-type_ATPase_cation)
putative ATP bindi...

511D

putative ATP binding site
511D, 512K, 513T, 604F, 626K, 627G, 628A, 658I, 719T, 720G, 721D, 810R, 813P, 816K, 835D, 838N
CDD
cd07543 (P-type_ATPase_cation)

512K

putative ATP binding site
511D, 512K, 513T, 604F, 626K, 627G, 628A, 658I, 719T, 720G, 721D, 810R, 813P, 816K, 835D, 838N
CDD
cd07543 (P-type_ATPase_cation)

513T

putative ATP binding site
511D, 512K, 513T, 604F, 626K, 627G, 628A, 658I, 719T, 720G, 721D, 810R, 813P, 816K, 835D, 838N
CDD
cd07543 (P-type_ATPase_cation)

604F

putative ATP binding site
511D, 512K, 513T, 604F, 626K, 627G, 628A, 658I, 719T, 720G, 721D, 810R, 813P, 816K, 835D, 838N
CDD
cd07543 (P-type_ATPase_cation)

626K

putative ATP binding site
511D, 512K, 513T, 604F, 626K, 627G, 628A, 658I, 719T, 720G, 721D, 810R, 813P, 816K, 835D, 838N
CDD
cd07543 (P-type_ATPase_cation)

627G

putative ATP binding site
511D, 512K, 513T, 604F, 626K, 627G, 628A, 658I, 719T, 720G, 721D, 810R, 813P, 816K, 835D, 838N
CDD
cd07543 (P-type_ATPase_cation)

628A

putative ATP binding site
511D, 512K, 513T, 604F, 626K, 627G, 628A, 658I, 719T, 720G, 721D, 810R, 813P, 816K, 835D, 838N
CDD
cd07543 (P-type_ATPase_cation)

658I

putative ATP binding site
511D, 512K, 513T, 604F, 626K, 627G, 628A, 658I, 719T, 720G, 721D, 810R, 813P, 816K, 835D, 838N
CDD
cd07543 (P-type_ATPase_cation)

719T

putative ATP binding site
511D, 512K, 513T, 604F, 626K, 627G, 628A, 658I, 719T, 720G, 721D, 810R, 813P, 816K, 835D, 838N
CDD
cd07543 (P-type_ATPase_cation)

720G

putative ATP binding site
511D, 512K, 513T, 604F, 626K, 627G, 628A, 658I, 719T, 720G, 721D, 810R, 813P, 816K, 835D, 838N
CDD
cd07543 (P-type_ATPase_cation)

721D

putative ATP binding site
511D, 512K, 513T, 604F, 626K, 627G, 628A, 658I, 719T, 720G, 721D, 810R, 813P, 816K, 835D, 838N
CDD
cd07543 (P-type_ATPase_cation)

810R

putative ATP binding site
511D, 512K, 513T, 604F, 626K, 627G, 628A, 658I, 719T, 720G, 721D, 810R, 813P, 816K, 835D, 838N
CDD
cd07543 (P-type_ATPase_cation)

813P

putative ATP binding site
511D, 512K, 513T, 604F, 626K, 627G, 628A, 658I, 719T, 720G, 721D, 810R, 813P, 816K, 835D, 838N
CDD
cd07543 (P-type_ATPase_cation)

816K

putative ATP binding site
511D, 512K, 513T, 604F, 626K, 627G, 628A, 658I, 719T, 720G, 721D, 810R, 813P, 816K, 835D, 838N
CDD
cd07543 (P-type_ATPase_cation)

835D

putative ATP binding site
511D, 512K, 513T, 604F, 626K, 627G, 628A, 658I, 719T, 720G, 721D, 810R, 813P, 816K, 835D, 838N
CDD
cd07543 (P-type_ATPase_cation)

838N

putative ATP binding site
511D, 512K, 513T, 604F, 626K, 627G, 628A, 658I, 719T, 720G, 721D, 810R, 813P, 816K, 835D, 838N
CDD
cd07543 (P-type_ATPase_cation)
SFLDF00027

512K

probable role in phosphate transfer from ATP
512K
SFLD
SFLDF00027 (p-type_atpase)
SFLDF00027

513T

conserved in all p-type atpases
513T, 514G, 515T
SFLD
SFLDF00027 (p-type_atpase)

514G

conserved in all p-type atpases
513T, 514G, 515T
SFLD
SFLDF00027 (p-type_atpase)

515T

conserved in all p-type atpases
513T, 514G, 515T
SFLD
SFLDF00027 (p-type_atpase)
SFLDF00027

719T

coordinates with phosphate oxygen from ATP
719T
SFLD
SFLDF00027 (p-type_atpase)
SFLDF00027

816K

stabilizes transition state of phosphoryl transfer by contacting beta & gamma phosphate oxygens of ATP
816K
SFLD
SFLDF00027 (p-type_atpase)
SFLDF00027

835D

Mg2+ ligand
835D, 839D
SFLD
SFLDF00027 (p-type_atpase)

839D

Mg2+ ligand
835D, 839D
SFLD
SFLDF00027 (p-type_atpase)
putative cation bi...

1,019K

putative cation binding site
1,019K, 1,023L, 1,024N, 1,026L, 1,027A, 1,054T, 1,057F, 1,058F
CDD
cd07543 (P-type_ATPase_cation)

1,023L

putative cation binding site
1,019K, 1,023L, 1,024N, 1,026L, 1,027A, 1,054T, 1,057F, 1,058F
CDD
cd07543 (P-type_ATPase_cation)

1,024N

putative cation binding site
1,019K, 1,023L, 1,024N, 1,026L, 1,027A, 1,054T, 1,057F, 1,058F
CDD
cd07543 (P-type_ATPase_cation)

1,026L

putative cation binding site
1,019K, 1,023L, 1,024N, 1,026L, 1,027A, 1,054T, 1,057F, 1,058F
CDD
cd07543 (P-type_ATPase_cation)

1,027A

putative cation binding site
1,019K, 1,023L, 1,024N, 1,026L, 1,027A, 1,054T, 1,057F, 1,058F
CDD
cd07543 (P-type_ATPase_cation)

1,054T

putative cation binding site
1,019K, 1,023L, 1,024N, 1,026L, 1,027A, 1,054T, 1,057F, 1,058F
CDD
cd07543 (P-type_ATPase_cation)

1,057F

putative cation binding site
1,019K, 1,023L, 1,024N, 1,026L, 1,027A, 1,054T, 1,057F, 1,058F
CDD
cd07543 (P-type_ATPase_cation)

1,058F

putative cation binding site
1,019K, 1,023L, 1,024N, 1,026L, 1,027A, 1,054T, 1,057F, 1,058F
CDD
cd07543 (P-type_ATPase_cation)

GO term prediction

Biological Process

GO:0006812 cation transport

Molecular Function

GO:0000166 nucleotide binding
GO:0016887 ATPase activity

Cellular Component

GO:0016021 integral component of membrane

Filter view on

Entry type

Status

Per-residue features