Mp5g24070.1

Protein

Length

491 amino acids

Protein family membership

None predicted.

Homologous superfamilies

Homologous superfamily
96 - 457
NAD(P)-binding domain superfamily (IPR036291)

1 50 100 150 200 250 300 350 400 450 491

Domains and repeats

Domain
98 - 386
NAD-dependent epimerase/dehydratase (IPR001509)

1 50 100 150 200 250 300 350 400 450 491

Detailed signature matches

IPR036291

NAD(P)-binding domain superfamily
1. SSF51735 (NAD(P)-bi...)
  
  96 - 457
  
  SUPERFAMILY
  SSF51735 (NAD(P)-binding Rossmann-fold domains)
IPR001509

NAD-dependent epimerase/dehydratase
1. PF01370 (Epimerase)
  
  98 - 386
  
  Pfam
  PF01370 (Epimerase)

no IPR

Unintegrated signatures

G3DSA:3.40.50...

362 - 388

GENE3D
G3DSA:3.40.50.720 (G3DSA:3.40.50.720)

97 - 303

GENE3D
G3DSA:3.40.50.720 (G3DSA:3.40.50.720)
G3DSA:3.90.25.10

304 - 361

GENE3D
G3DSA:3.90.25.10 (G3DSA:3.90.25.10)

389 - 465

GENE3D
G3DSA:3.90.25.10 (G3DSA:3.90.25.10)
PTHR43000 (DTDP-D-G...)

87 - 487

PANTHER
PTHR43000 (DTDP-D-GLUCOSE 4,6-DEHYDRATASE-RELATED)
PTHR43000:SF10 (UDP...)

87 - 487

PANTHER
PTHR43000:SF10 (UDP-SULFOQUINOVOSE SYNTHASE, CHLOROPLASTIC)
cd05255 (SQD1_like_...)

97 - 477

CDD
cd05255 (SQD1_like_SDR_e)

Residue annotation

NAD binding site c...

102G

NAD binding site
102G, 104D, 105G, 106Y, 107C, 126D, 127S, 128L, 129V, 130R, 168G, 169D, 170I, 191F, 192G, 193E, 195R, 213N, 237L, 276Y, 280K, 303Q, 304G, 306V
CDD
cd05255 (SQD1_like_SDR_e)

104D

NAD binding site
102G, 104D, 105G, 106Y, 107C, 126D, 127S, 128L, 129V, 130R, 168G, 169D, 170I, 191F, 192G, 193E, 195R, 213N, 237L, 276Y, 280K, 303Q, 304G, 306V
CDD
cd05255 (SQD1_like_SDR_e)

105G

NAD binding site
102G, 104D, 105G, 106Y, 107C, 126D, 127S, 128L, 129V, 130R, 168G, 169D, 170I, 191F, 192G, 193E, 195R, 213N, 237L, 276Y, 280K, 303Q, 304G, 306V
CDD
cd05255 (SQD1_like_SDR_e)

106Y

NAD binding site
102G, 104D, 105G, 106Y, 107C, 126D, 127S, 128L, 129V, 130R, 168G, 169D, 170I, 191F, 192G, 193E, 195R, 213N, 237L, 276Y, 280K, 303Q, 304G, 306V
CDD
cd05255 (SQD1_like_SDR_e)

107C

NAD binding site
102G, 104D, 105G, 106Y, 107C, 126D, 127S, 128L, 129V, 130R, 168G, 169D, 170I, 191F, 192G, 193E, 195R, 213N, 237L, 276Y, 280K, 303Q, 304G, 306V
CDD
cd05255 (SQD1_like_SDR_e)

126D

NAD binding site
102G, 104D, 105G, 106Y, 107C, 126D, 127S, 128L, 129V, 130R, 168G, 169D, 170I, 191F, 192G, 193E, 195R, 213N, 237L, 276Y, 280K, 303Q, 304G, 306V
CDD
cd05255 (SQD1_like_SDR_e)

127S

NAD binding site
102G, 104D, 105G, 106Y, 107C, 126D, 127S, 128L, 129V, 130R, 168G, 169D, 170I, 191F, 192G, 193E, 195R, 213N, 237L, 276Y, 280K, 303Q, 304G, 306V
CDD
cd05255 (SQD1_like_SDR_e)

128L

NAD binding site
102G, 104D, 105G, 106Y, 107C, 126D, 127S, 128L, 129V, 130R, 168G, 169D, 170I, 191F, 192G, 193E, 195R, 213N, 237L, 276Y, 280K, 303Q, 304G, 306V
CDD
cd05255 (SQD1_like_SDR_e)

129V

NAD binding site
102G, 104D, 105G, 106Y, 107C, 126D, 127S, 128L, 129V, 130R, 168G, 169D, 170I, 191F, 192G, 193E, 195R, 213N, 237L, 276Y, 280K, 303Q, 304G, 306V
CDD
cd05255 (SQD1_like_SDR_e)

130R

NAD binding site
102G, 104D, 105G, 106Y, 107C, 126D, 127S, 128L, 129V, 130R, 168G, 169D, 170I, 191F, 192G, 193E, 195R, 213N, 237L, 276Y, 280K, 303Q, 304G, 306V
CDD
cd05255 (SQD1_like_SDR_e)

168G

NAD binding site
102G, 104D, 105G, 106Y, 107C, 126D, 127S, 128L, 129V, 130R, 168G, 169D, 170I, 191F, 192G, 193E, 195R, 213N, 237L, 276Y, 280K, 303Q, 304G, 306V
CDD
cd05255 (SQD1_like_SDR_e)

169D

NAD binding site
102G, 104D, 105G, 106Y, 107C, 126D, 127S, 128L, 129V, 130R, 168G, 169D, 170I, 191F, 192G, 193E, 195R, 213N, 237L, 276Y, 280K, 303Q, 304G, 306V
CDD
cd05255 (SQD1_like_SDR_e)

170I

NAD binding site
102G, 104D, 105G, 106Y, 107C, 126D, 127S, 128L, 129V, 130R, 168G, 169D, 170I, 191F, 192G, 193E, 195R, 213N, 237L, 276Y, 280K, 303Q, 304G, 306V
CDD
cd05255 (SQD1_like_SDR_e)

191F

NAD binding site
102G, 104D, 105G, 106Y, 107C, 126D, 127S, 128L, 129V, 130R, 168G, 169D, 170I, 191F, 192G, 193E, 195R, 213N, 237L, 276Y, 280K, 303Q, 304G, 306V
CDD
cd05255 (SQD1_like_SDR_e)

192G

NAD binding site
102G, 104D, 105G, 106Y, 107C, 126D, 127S, 128L, 129V, 130R, 168G, 169D, 170I, 191F, 192G, 193E, 195R, 213N, 237L, 276Y, 280K, 303Q, 304G, 306V
CDD
cd05255 (SQD1_like_SDR_e)

193E

NAD binding site
102G, 104D, 105G, 106Y, 107C, 126D, 127S, 128L, 129V, 130R, 168G, 169D, 170I, 191F, 192G, 193E, 195R, 213N, 237L, 276Y, 280K, 303Q, 304G, 306V
CDD
cd05255 (SQD1_like_SDR_e)

195R

NAD binding site
102G, 104D, 105G, 106Y, 107C, 126D, 127S, 128L, 129V, 130R, 168G, 169D, 170I, 191F, 192G, 193E, 195R, 213N, 237L, 276Y, 280K, 303Q, 304G, 306V
CDD
cd05255 (SQD1_like_SDR_e)

213N

NAD binding site
102G, 104D, 105G, 106Y, 107C, 126D, 127S, 128L, 129V, 130R, 168G, 169D, 170I, 191F, 192G, 193E, 195R, 213N, 237L, 276Y, 280K, 303Q, 304G, 306V
CDD
cd05255 (SQD1_like_SDR_e)

237L

NAD binding site
102G, 104D, 105G, 106Y, 107C, 126D, 127S, 128L, 129V, 130R, 168G, 169D, 170I, 191F, 192G, 193E, 195R, 213N, 237L, 276Y, 280K, 303Q, 304G, 306V
CDD
cd05255 (SQD1_like_SDR_e)

276Y

NAD binding site
102G, 104D, 105G, 106Y, 107C, 126D, 127S, 128L, 129V, 130R, 168G, 169D, 170I, 191F, 192G, 193E, 195R, 213N, 237L, 276Y, 280K, 303Q, 304G, 306V
CDD
cd05255 (SQD1_like_SDR_e)

280K

NAD binding site
102G, 104D, 105G, 106Y, 107C, 126D, 127S, 128L, 129V, 130R, 168G, 169D, 170I, 191F, 192G, 193E, 195R, 213N, 237L, 276Y, 280K, 303Q, 304G, 306V
CDD
cd05255 (SQD1_like_SDR_e)

303Q

NAD binding site
102G, 104D, 105G, 106Y, 107C, 126D, 127S, 128L, 129V, 130R, 168G, 169D, 170I, 191F, 192G, 193E, 195R, 213N, 237L, 276Y, 280K, 303Q, 304G, 306V
CDD
cd05255 (SQD1_like_SDR_e)

304G

NAD binding site
102G, 104D, 105G, 106Y, 107C, 126D, 127S, 128L, 129V, 130R, 168G, 169D, 170I, 191F, 192G, 193E, 195R, 213N, 237L, 276Y, 280K, 303Q, 304G, 306V
CDD
cd05255 (SQD1_like_SDR_e)

306V

NAD binding site
102G, 104D, 105G, 106Y, 107C, 126D, 127S, 128L, 129V, 130R, 168G, 169D, 170I, 191F, 192G, 193E, 195R, 213N, 237L, 276Y, 280K, 303Q, 304G, 306V
CDD
cd05255 (SQD1_like_SDR_e)
substrate binding ...

195R

substrate binding site
195R, 197A, 239T, 240M, 241G, 276Y, 277H, 303Q, 304G, 305V, 332T, 333A, 336R, 337F, 348T, 350Y, 355Q, 357R, 394V, 421R, 423E
CDD
cd05255 (SQD1_like_SDR_e)

197A

substrate binding site
195R, 197A, 239T, 240M, 241G, 276Y, 277H, 303Q, 304G, 305V, 332T, 333A, 336R, 337F, 348T, 350Y, 355Q, 357R, 394V, 421R, 423E
CDD
cd05255 (SQD1_like_SDR_e)

239T

substrate binding site
195R, 197A, 239T, 240M, 241G, 276Y, 277H, 303Q, 304G, 305V, 332T, 333A, 336R, 337F, 348T, 350Y, 355Q, 357R, 394V, 421R, 423E
CDD
cd05255 (SQD1_like_SDR_e)

240M

substrate binding site
195R, 197A, 239T, 240M, 241G, 276Y, 277H, 303Q, 304G, 305V, 332T, 333A, 336R, 337F, 348T, 350Y, 355Q, 357R, 394V, 421R, 423E
CDD
cd05255 (SQD1_like_SDR_e)

241G

substrate binding site
195R, 197A, 239T, 240M, 241G, 276Y, 277H, 303Q, 304G, 305V, 332T, 333A, 336R, 337F, 348T, 350Y, 355Q, 357R, 394V, 421R, 423E
CDD
cd05255 (SQD1_like_SDR_e)

276Y

substrate binding site
195R, 197A, 239T, 240M, 241G, 276Y, 277H, 303Q, 304G, 305V, 332T, 333A, 336R, 337F, 348T, 350Y, 355Q, 357R, 394V, 421R, 423E
CDD
cd05255 (SQD1_like_SDR_e)

277H

substrate binding site
195R, 197A, 239T, 240M, 241G, 276Y, 277H, 303Q, 304G, 305V, 332T, 333A, 336R, 337F, 348T, 350Y, 355Q, 357R, 394V, 421R, 423E
CDD
cd05255 (SQD1_like_SDR_e)

303Q

substrate binding site
195R, 197A, 239T, 240M, 241G, 276Y, 277H, 303Q, 304G, 305V, 332T, 333A, 336R, 337F, 348T, 350Y, 355Q, 357R, 394V, 421R, 423E
CDD
cd05255 (SQD1_like_SDR_e)

304G

substrate binding site
195R, 197A, 239T, 240M, 241G, 276Y, 277H, 303Q, 304G, 305V, 332T, 333A, 336R, 337F, 348T, 350Y, 355Q, 357R, 394V, 421R, 423E
CDD
cd05255 (SQD1_like_SDR_e)

305V

substrate binding site
195R, 197A, 239T, 240M, 241G, 276Y, 277H, 303Q, 304G, 305V, 332T, 333A, 336R, 337F, 348T, 350Y, 355Q, 357R, 394V, 421R, 423E
CDD
cd05255 (SQD1_like_SDR_e)

332T

substrate binding site
195R, 197A, 239T, 240M, 241G, 276Y, 277H, 303Q, 304G, 305V, 332T, 333A, 336R, 337F, 348T, 350Y, 355Q, 357R, 394V, 421R, 423E
CDD
cd05255 (SQD1_like_SDR_e)

333A

substrate binding site
195R, 197A, 239T, 240M, 241G, 276Y, 277H, 303Q, 304G, 305V, 332T, 333A, 336R, 337F, 348T, 350Y, 355Q, 357R, 394V, 421R, 423E
CDD
cd05255 (SQD1_like_SDR_e)

336R

substrate binding site
195R, 197A, 239T, 240M, 241G, 276Y, 277H, 303Q, 304G, 305V, 332T, 333A, 336R, 337F, 348T, 350Y, 355Q, 357R, 394V, 421R, 423E
CDD
cd05255 (SQD1_like_SDR_e)

337F

substrate binding site
195R, 197A, 239T, 240M, 241G, 276Y, 277H, 303Q, 304G, 305V, 332T, 333A, 336R, 337F, 348T, 350Y, 355Q, 357R, 394V, 421R, 423E
CDD
cd05255 (SQD1_like_SDR_e)

348T

substrate binding site
195R, 197A, 239T, 240M, 241G, 276Y, 277H, 303Q, 304G, 305V, 332T, 333A, 336R, 337F, 348T, 350Y, 355Q, 357R, 394V, 421R, 423E
CDD
cd05255 (SQD1_like_SDR_e)

350Y

substrate binding site
195R, 197A, 239T, 240M, 241G, 276Y, 277H, 303Q, 304G, 305V, 332T, 333A, 336R, 337F, 348T, 350Y, 355Q, 357R, 394V, 421R, 423E
CDD
cd05255 (SQD1_like_SDR_e)

355Q

substrate binding site
195R, 197A, 239T, 240M, 241G, 276Y, 277H, 303Q, 304G, 305V, 332T, 333A, 336R, 337F, 348T, 350Y, 355Q, 357R, 394V, 421R, 423E
CDD
cd05255 (SQD1_like_SDR_e)

357R

substrate binding site
195R, 197A, 239T, 240M, 241G, 276Y, 277H, 303Q, 304G, 305V, 332T, 333A, 336R, 337F, 348T, 350Y, 355Q, 357R, 394V, 421R, 423E
CDD
cd05255 (SQD1_like_SDR_e)

394V

substrate binding site
195R, 197A, 239T, 240M, 241G, 276Y, 277H, 303Q, 304G, 305V, 332T, 333A, 336R, 337F, 348T, 350Y, 355Q, 357R, 394V, 421R, 423E
CDD
cd05255 (SQD1_like_SDR_e)

421R

substrate binding site
195R, 197A, 239T, 240M, 241G, 276Y, 277H, 303Q, 304G, 305V, 332T, 333A, 336R, 337F, 348T, 350Y, 355Q, 357R, 394V, 421R, 423E
CDD
cd05255 (SQD1_like_SDR_e)

423E

substrate binding site
195R, 197A, 239T, 240M, 241G, 276Y, 277H, 303Q, 304G, 305V, 332T, 333A, 336R, 337F, 348T, 350Y, 355Q, 357R, 394V, 421R, 423E
CDD
cd05255 (SQD1_like_SDR_e)
active site cd05255

214N

active site
214N, 239T, 276Y, 280K
CDD
cd05255 (SQD1_like_SDR_e)

239T

active site
214N, 239T, 276Y, 280K
CDD
cd05255 (SQD1_like_SDR_e)

276Y

active site
214N, 239T, 276Y, 280K
CDD
cd05255 (SQD1_like_SDR_e)

280K

active site
214N, 239T, 276Y, 280K
CDD
cd05255 (SQD1_like_SDR_e)

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0003824 catalytic activity

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

Mp5g24070.1

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component