Mp7g19180.1

Protein

Length

421 amino acids

Protein family membership

UDP-glucose 4-epimerase (IPR005886)

Homologous superfamilies

Homologous superfamily
75 - 412
NAD(P)-binding domain superfamily (IPR036291)

1 50 100 150 200 250 300 350 421

Domains and repeats

Domain
77 - 392
NAD(P)-binding domain (IPR016040)

1 50 100 150 200 250 300 350 421

Detailed signature matches

IPR036291

NAD(P)-binding domain superfamily
1. SSF51735 (NAD(P)-bi...)
  
  75 - 412
  
  SUPERFAMILY
  SSF51735 (NAD(P)-binding Rossmann-fold domains)
IPR005886

UDP-glucose 4-epimerase
1. TIGR01179
  
  76 - 413
  
  TIGRFAMs
  TIGR01179 (TIGR01179)
2. cd05247 (UDP_G4E_1_...)
  
  75 - 408
  
  CDD
  cd05247 (UDP_G4E_1_SDR_e)
IPR016040

NAD(P)-binding domain
1. PF16363 (GDP_Man_Dehyd)
  
  77 - 392
  
  Pfam
  PF16363 (GDP_Man_Dehyd)

no IPR

Unintegrated signatures

G3DSA:3.40.50...

76 - 268

GENE3D
G3DSA:3.40.50.720 (G3DSA:3.40.50.720)

322 - 351

GENE3D
G3DSA:3.40.50.720 (G3DSA:3.40.50.720)
G3DSA:3.90.25.10

269 - 321

GENE3D
G3DSA:3.90.25.10 (G3DSA:3.90.25.10)

352 - 407

GENE3D
G3DSA:3.90.25.10 (G3DSA:3.90.25.10)
PTHR43349 (PINORESI...)

51 - 407

PANTHER
PTHR43349 (PINORESINOL REDUCTASE-RELATED)
PTHR43349:SF75 (UDP...)

51 - 407

PANTHER
PTHR43349:SF75 (UDP-ARABINOSE 4-EPIMERASE 3-RELATED)

Other features

mobidb-lite (disord...)

1 - 22

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

NAD binding site c...

80G

NAD binding site
80G, 82A, 83G, 84Y, 85I, 104D, 105N, 106L, 107S, 108R, 109G, 132A, 133D, 134L, 155F, 156A, 157A, 159A, 174N, 197S, 198S, 199T, 223Y, 227K, 252Y, 253F, 255V
CDD
cd05247 (UDP_G4E_1_SDR_e)

82A

NAD binding site
80G, 82A, 83G, 84Y, 85I, 104D, 105N, 106L, 107S, 108R, 109G, 132A, 133D, 134L, 155F, 156A, 157A, 159A, 174N, 197S, 198S, 199T, 223Y, 227K, 252Y, 253F, 255V
CDD
cd05247 (UDP_G4E_1_SDR_e)

83G

NAD binding site
80G, 82A, 83G, 84Y, 85I, 104D, 105N, 106L, 107S, 108R, 109G, 132A, 133D, 134L, 155F, 156A, 157A, 159A, 174N, 197S, 198S, 199T, 223Y, 227K, 252Y, 253F, 255V
CDD
cd05247 (UDP_G4E_1_SDR_e)

84Y

NAD binding site
80G, 82A, 83G, 84Y, 85I, 104D, 105N, 106L, 107S, 108R, 109G, 132A, 133D, 134L, 155F, 156A, 157A, 159A, 174N, 197S, 198S, 199T, 223Y, 227K, 252Y, 253F, 255V
CDD
cd05247 (UDP_G4E_1_SDR_e)

85I

NAD binding site
80G, 82A, 83G, 84Y, 85I, 104D, 105N, 106L, 107S, 108R, 109G, 132A, 133D, 134L, 155F, 156A, 157A, 159A, 174N, 197S, 198S, 199T, 223Y, 227K, 252Y, 253F, 255V
CDD
cd05247 (UDP_G4E_1_SDR_e)

104D

NAD binding site
80G, 82A, 83G, 84Y, 85I, 104D, 105N, 106L, 107S, 108R, 109G, 132A, 133D, 134L, 155F, 156A, 157A, 159A, 174N, 197S, 198S, 199T, 223Y, 227K, 252Y, 253F, 255V
CDD
cd05247 (UDP_G4E_1_SDR_e)

105N

NAD binding site
80G, 82A, 83G, 84Y, 85I, 104D, 105N, 106L, 107S, 108R, 109G, 132A, 133D, 134L, 155F, 156A, 157A, 159A, 174N, 197S, 198S, 199T, 223Y, 227K, 252Y, 253F, 255V
CDD
cd05247 (UDP_G4E_1_SDR_e)

106L

NAD binding site
80G, 82A, 83G, 84Y, 85I, 104D, 105N, 106L, 107S, 108R, 109G, 132A, 133D, 134L, 155F, 156A, 157A, 159A, 174N, 197S, 198S, 199T, 223Y, 227K, 252Y, 253F, 255V
CDD
cd05247 (UDP_G4E_1_SDR_e)

107S

NAD binding site
80G, 82A, 83G, 84Y, 85I, 104D, 105N, 106L, 107S, 108R, 109G, 132A, 133D, 134L, 155F, 156A, 157A, 159A, 174N, 197S, 198S, 199T, 223Y, 227K, 252Y, 253F, 255V
CDD
cd05247 (UDP_G4E_1_SDR_e)

108R

NAD binding site
80G, 82A, 83G, 84Y, 85I, 104D, 105N, 106L, 107S, 108R, 109G, 132A, 133D, 134L, 155F, 156A, 157A, 159A, 174N, 197S, 198S, 199T, 223Y, 227K, 252Y, 253F, 255V
CDD
cd05247 (UDP_G4E_1_SDR_e)

109G

NAD binding site
80G, 82A, 83G, 84Y, 85I, 104D, 105N, 106L, 107S, 108R, 109G, 132A, 133D, 134L, 155F, 156A, 157A, 159A, 174N, 197S, 198S, 199T, 223Y, 227K, 252Y, 253F, 255V
CDD
cd05247 (UDP_G4E_1_SDR_e)

132A

NAD binding site
80G, 82A, 83G, 84Y, 85I, 104D, 105N, 106L, 107S, 108R, 109G, 132A, 133D, 134L, 155F, 156A, 157A, 159A, 174N, 197S, 198S, 199T, 223Y, 227K, 252Y, 253F, 255V
CDD
cd05247 (UDP_G4E_1_SDR_e)

133D

NAD binding site
80G, 82A, 83G, 84Y, 85I, 104D, 105N, 106L, 107S, 108R, 109G, 132A, 133D, 134L, 155F, 156A, 157A, 159A, 174N, 197S, 198S, 199T, 223Y, 227K, 252Y, 253F, 255V
CDD
cd05247 (UDP_G4E_1_SDR_e)

134L

NAD binding site
80G, 82A, 83G, 84Y, 85I, 104D, 105N, 106L, 107S, 108R, 109G, 132A, 133D, 134L, 155F, 156A, 157A, 159A, 174N, 197S, 198S, 199T, 223Y, 227K, 252Y, 253F, 255V
CDD
cd05247 (UDP_G4E_1_SDR_e)

155F

NAD binding site
80G, 82A, 83G, 84Y, 85I, 104D, 105N, 106L, 107S, 108R, 109G, 132A, 133D, 134L, 155F, 156A, 157A, 159A, 174N, 197S, 198S, 199T, 223Y, 227K, 252Y, 253F, 255V
CDD
cd05247 (UDP_G4E_1_SDR_e)

156A

NAD binding site
80G, 82A, 83G, 84Y, 85I, 104D, 105N, 106L, 107S, 108R, 109G, 132A, 133D, 134L, 155F, 156A, 157A, 159A, 174N, 197S, 198S, 199T, 223Y, 227K, 252Y, 253F, 255V
CDD
cd05247 (UDP_G4E_1_SDR_e)

157A

NAD binding site
80G, 82A, 83G, 84Y, 85I, 104D, 105N, 106L, 107S, 108R, 109G, 132A, 133D, 134L, 155F, 156A, 157A, 159A, 174N, 197S, 198S, 199T, 223Y, 227K, 252Y, 253F, 255V
CDD
cd05247 (UDP_G4E_1_SDR_e)

159A

NAD binding site
80G, 82A, 83G, 84Y, 85I, 104D, 105N, 106L, 107S, 108R, 109G, 132A, 133D, 134L, 155F, 156A, 157A, 159A, 174N, 197S, 198S, 199T, 223Y, 227K, 252Y, 253F, 255V
CDD
cd05247 (UDP_G4E_1_SDR_e)

174N

NAD binding site
80G, 82A, 83G, 84Y, 85I, 104D, 105N, 106L, 107S, 108R, 109G, 132A, 133D, 134L, 155F, 156A, 157A, 159A, 174N, 197S, 198S, 199T, 223Y, 227K, 252Y, 253F, 255V
CDD
cd05247 (UDP_G4E_1_SDR_e)

197S

NAD binding site
80G, 82A, 83G, 84Y, 85I, 104D, 105N, 106L, 107S, 108R, 109G, 132A, 133D, 134L, 155F, 156A, 157A, 159A, 174N, 197S, 198S, 199T, 223Y, 227K, 252Y, 253F, 255V
CDD
cd05247 (UDP_G4E_1_SDR_e)

198S

NAD binding site
80G, 82A, 83G, 84Y, 85I, 104D, 105N, 106L, 107S, 108R, 109G, 132A, 133D, 134L, 155F, 156A, 157A, 159A, 174N, 197S, 198S, 199T, 223Y, 227K, 252Y, 253F, 255V
CDD
cd05247 (UDP_G4E_1_SDR_e)

199T

NAD binding site
80G, 82A, 83G, 84Y, 85I, 104D, 105N, 106L, 107S, 108R, 109G, 132A, 133D, 134L, 155F, 156A, 157A, 159A, 174N, 197S, 198S, 199T, 223Y, 227K, 252Y, 253F, 255V
CDD
cd05247 (UDP_G4E_1_SDR_e)

223Y

NAD binding site
80G, 82A, 83G, 84Y, 85I, 104D, 105N, 106L, 107S, 108R, 109G, 132A, 133D, 134L, 155F, 156A, 157A, 159A, 174N, 197S, 198S, 199T, 223Y, 227K, 252Y, 253F, 255V
CDD
cd05247 (UDP_G4E_1_SDR_e)

227K

NAD binding site
80G, 82A, 83G, 84Y, 85I, 104D, 105N, 106L, 107S, 108R, 109G, 132A, 133D, 134L, 155F, 156A, 157A, 159A, 174N, 197S, 198S, 199T, 223Y, 227K, 252Y, 253F, 255V
CDD
cd05247 (UDP_G4E_1_SDR_e)

252Y

NAD binding site
80G, 82A, 83G, 84Y, 85I, 104D, 105N, 106L, 107S, 108R, 109G, 132A, 133D, 134L, 155F, 156A, 157A, 159A, 174N, 197S, 198S, 199T, 223Y, 227K, 252Y, 253F, 255V
CDD
cd05247 (UDP_G4E_1_SDR_e)

253F

NAD binding site
80G, 82A, 83G, 84Y, 85I, 104D, 105N, 106L, 107S, 108R, 109G, 132A, 133D, 134L, 155F, 156A, 157A, 159A, 174N, 197S, 198S, 199T, 223Y, 227K, 252Y, 253F, 255V
CDD
cd05247 (UDP_G4E_1_SDR_e)

255V

NAD binding site
80G, 82A, 83G, 84Y, 85I, 104D, 105N, 106L, 107S, 108R, 109G, 132A, 133D, 134L, 155F, 156A, 157A, 159A, 174N, 197S, 198S, 199T, 223Y, 227K, 252Y, 253F, 255V
CDD
cd05247 (UDP_G4E_1_SDR_e)
homodimer interfac...

165M

homodimer interface
165M, 167E, 168P, 169L, 172Y, 173H, 176T, 177S, 180L, 181G, 183L, 184E, 187V, 222P, 225K, 229M, 232E, 233I, 235M, 236D, 237Y
CDD
cd05247 (UDP_G4E_1_SDR_e)

167E

homodimer interface
165M, 167E, 168P, 169L, 172Y, 173H, 176T, 177S, 180L, 181G, 183L, 184E, 187V, 222P, 225K, 229M, 232E, 233I, 235M, 236D, 237Y
CDD
cd05247 (UDP_G4E_1_SDR_e)

168P

homodimer interface
165M, 167E, 168P, 169L, 172Y, 173H, 176T, 177S, 180L, 181G, 183L, 184E, 187V, 222P, 225K, 229M, 232E, 233I, 235M, 236D, 237Y
CDD
cd05247 (UDP_G4E_1_SDR_e)

169L

homodimer interface
165M, 167E, 168P, 169L, 172Y, 173H, 176T, 177S, 180L, 181G, 183L, 184E, 187V, 222P, 225K, 229M, 232E, 233I, 235M, 236D, 237Y
CDD
cd05247 (UDP_G4E_1_SDR_e)

172Y

homodimer interface
165M, 167E, 168P, 169L, 172Y, 173H, 176T, 177S, 180L, 181G, 183L, 184E, 187V, 222P, 225K, 229M, 232E, 233I, 235M, 236D, 237Y
CDD
cd05247 (UDP_G4E_1_SDR_e)

173H

homodimer interface
165M, 167E, 168P, 169L, 172Y, 173H, 176T, 177S, 180L, 181G, 183L, 184E, 187V, 222P, 225K, 229M, 232E, 233I, 235M, 236D, 237Y
CDD
cd05247 (UDP_G4E_1_SDR_e)

176T

homodimer interface
165M, 167E, 168P, 169L, 172Y, 173H, 176T, 177S, 180L, 181G, 183L, 184E, 187V, 222P, 225K, 229M, 232E, 233I, 235M, 236D, 237Y
CDD
cd05247 (UDP_G4E_1_SDR_e)

177S

homodimer interface
165M, 167E, 168P, 169L, 172Y, 173H, 176T, 177S, 180L, 181G, 183L, 184E, 187V, 222P, 225K, 229M, 232E, 233I, 235M, 236D, 237Y
CDD
cd05247 (UDP_G4E_1_SDR_e)

180L

homodimer interface
165M, 167E, 168P, 169L, 172Y, 173H, 176T, 177S, 180L, 181G, 183L, 184E, 187V, 222P, 225K, 229M, 232E, 233I, 235M, 236D, 237Y
CDD
cd05247 (UDP_G4E_1_SDR_e)

181G

homodimer interface
165M, 167E, 168P, 169L, 172Y, 173H, 176T, 177S, 180L, 181G, 183L, 184E, 187V, 222P, 225K, 229M, 232E, 233I, 235M, 236D, 237Y
CDD
cd05247 (UDP_G4E_1_SDR_e)

183L

homodimer interface
165M, 167E, 168P, 169L, 172Y, 173H, 176T, 177S, 180L, 181G, 183L, 184E, 187V, 222P, 225K, 229M, 232E, 233I, 235M, 236D, 237Y
CDD
cd05247 (UDP_G4E_1_SDR_e)

184E

homodimer interface
165M, 167E, 168P, 169L, 172Y, 173H, 176T, 177S, 180L, 181G, 183L, 184E, 187V, 222P, 225K, 229M, 232E, 233I, 235M, 236D, 237Y
CDD
cd05247 (UDP_G4E_1_SDR_e)

187V

homodimer interface
165M, 167E, 168P, 169L, 172Y, 173H, 176T, 177S, 180L, 181G, 183L, 184E, 187V, 222P, 225K, 229M, 232E, 233I, 235M, 236D, 237Y
CDD
cd05247 (UDP_G4E_1_SDR_e)

222P

homodimer interface
165M, 167E, 168P, 169L, 172Y, 173H, 176T, 177S, 180L, 181G, 183L, 184E, 187V, 222P, 225K, 229M, 232E, 233I, 235M, 236D, 237Y
CDD
cd05247 (UDP_G4E_1_SDR_e)

225K

homodimer interface
165M, 167E, 168P, 169L, 172Y, 173H, 176T, 177S, 180L, 181G, 183L, 184E, 187V, 222P, 225K, 229M, 232E, 233I, 235M, 236D, 237Y
CDD
cd05247 (UDP_G4E_1_SDR_e)

229M

homodimer interface
165M, 167E, 168P, 169L, 172Y, 173H, 176T, 177S, 180L, 181G, 183L, 184E, 187V, 222P, 225K, 229M, 232E, 233I, 235M, 236D, 237Y
CDD
cd05247 (UDP_G4E_1_SDR_e)

232E

homodimer interface
165M, 167E, 168P, 169L, 172Y, 173H, 176T, 177S, 180L, 181G, 183L, 184E, 187V, 222P, 225K, 229M, 232E, 233I, 235M, 236D, 237Y
CDD
cd05247 (UDP_G4E_1_SDR_e)

233I

homodimer interface
165M, 167E, 168P, 169L, 172Y, 173H, 176T, 177S, 180L, 181G, 183L, 184E, 187V, 222P, 225K, 229M, 232E, 233I, 235M, 236D, 237Y
CDD
cd05247 (UDP_G4E_1_SDR_e)

235M

homodimer interface
165M, 167E, 168P, 169L, 172Y, 173H, 176T, 177S, 180L, 181G, 183L, 184E, 187V, 222P, 225K, 229M, 232E, 233I, 235M, 236D, 237Y
CDD
cd05247 (UDP_G4E_1_SDR_e)

236D

homodimer interface
165M, 167E, 168P, 169L, 172Y, 173H, 176T, 177S, 180L, 181G, 183L, 184E, 187V, 222P, 225K, 229M, 232E, 233I, 235M, 236D, 237Y
CDD
cd05247 (UDP_G4E_1_SDR_e)

237Y

homodimer interface
165M, 167E, 168P, 169L, 172Y, 173H, 176T, 177S, 180L, 181G, 183L, 184E, 187V, 222P, 225K, 229M, 232E, 233I, 235M, 236D, 237Y
CDD
cd05247 (UDP_G4E_1_SDR_e)
active site cd05247

175I

active site
175I, 199T, 223Y, 227K
CDD
cd05247 (UDP_G4E_1_SDR_e)

199T

active site
175I, 199T, 223Y, 227K
CDD
cd05247 (UDP_G4E_1_SDR_e)

223Y

active site
175I, 199T, 223Y, 227K
CDD
cd05247 (UDP_G4E_1_SDR_e)

227K

active site
175I, 199T, 223Y, 227K
CDD
cd05247 (UDP_G4E_1_SDR_e)
substrate binding ...

199T

substrate binding site
199T, 200C, 201A, 223Y, 252Y, 253F, 254N, 276G, 277R, 278I, 293L, 294Q, 295V, 296K, 307C, 309R, 311Y, 346V, 369R, 372D
CDD
cd05247 (UDP_G4E_1_SDR_e)

200C

substrate binding site
199T, 200C, 201A, 223Y, 252Y, 253F, 254N, 276G, 277R, 278I, 293L, 294Q, 295V, 296K, 307C, 309R, 311Y, 346V, 369R, 372D
CDD
cd05247 (UDP_G4E_1_SDR_e)

201A

substrate binding site
199T, 200C, 201A, 223Y, 252Y, 253F, 254N, 276G, 277R, 278I, 293L, 294Q, 295V, 296K, 307C, 309R, 311Y, 346V, 369R, 372D
CDD
cd05247 (UDP_G4E_1_SDR_e)

223Y

substrate binding site
199T, 200C, 201A, 223Y, 252Y, 253F, 254N, 276G, 277R, 278I, 293L, 294Q, 295V, 296K, 307C, 309R, 311Y, 346V, 369R, 372D
CDD
cd05247 (UDP_G4E_1_SDR_e)

252Y

substrate binding site
199T, 200C, 201A, 223Y, 252Y, 253F, 254N, 276G, 277R, 278I, 293L, 294Q, 295V, 296K, 307C, 309R, 311Y, 346V, 369R, 372D
CDD
cd05247 (UDP_G4E_1_SDR_e)

253F

substrate binding site
199T, 200C, 201A, 223Y, 252Y, 253F, 254N, 276G, 277R, 278I, 293L, 294Q, 295V, 296K, 307C, 309R, 311Y, 346V, 369R, 372D
CDD
cd05247 (UDP_G4E_1_SDR_e)

254N

substrate binding site
199T, 200C, 201A, 223Y, 252Y, 253F, 254N, 276G, 277R, 278I, 293L, 294Q, 295V, 296K, 307C, 309R, 311Y, 346V, 369R, 372D
CDD
cd05247 (UDP_G4E_1_SDR_e)

276G

substrate binding site
199T, 200C, 201A, 223Y, 252Y, 253F, 254N, 276G, 277R, 278I, 293L, 294Q, 295V, 296K, 307C, 309R, 311Y, 346V, 369R, 372D
CDD
cd05247 (UDP_G4E_1_SDR_e)

277R

substrate binding site
199T, 200C, 201A, 223Y, 252Y, 253F, 254N, 276G, 277R, 278I, 293L, 294Q, 295V, 296K, 307C, 309R, 311Y, 346V, 369R, 372D
CDD
cd05247 (UDP_G4E_1_SDR_e)

278I

substrate binding site
199T, 200C, 201A, 223Y, 252Y, 253F, 254N, 276G, 277R, 278I, 293L, 294Q, 295V, 296K, 307C, 309R, 311Y, 346V, 369R, 372D
CDD
cd05247 (UDP_G4E_1_SDR_e)

293L

substrate binding site
199T, 200C, 201A, 223Y, 252Y, 253F, 254N, 276G, 277R, 278I, 293L, 294Q, 295V, 296K, 307C, 309R, 311Y, 346V, 369R, 372D
CDD
cd05247 (UDP_G4E_1_SDR_e)

294Q

substrate binding site
199T, 200C, 201A, 223Y, 252Y, 253F, 254N, 276G, 277R, 278I, 293L, 294Q, 295V, 296K, 307C, 309R, 311Y, 346V, 369R, 372D
CDD
cd05247 (UDP_G4E_1_SDR_e)

295V

substrate binding site
199T, 200C, 201A, 223Y, 252Y, 253F, 254N, 276G, 277R, 278I, 293L, 294Q, 295V, 296K, 307C, 309R, 311Y, 346V, 369R, 372D
CDD
cd05247 (UDP_G4E_1_SDR_e)

296K

substrate binding site
199T, 200C, 201A, 223Y, 252Y, 253F, 254N, 276G, 277R, 278I, 293L, 294Q, 295V, 296K, 307C, 309R, 311Y, 346V, 369R, 372D
CDD
cd05247 (UDP_G4E_1_SDR_e)

307C

substrate binding site
199T, 200C, 201A, 223Y, 252Y, 253F, 254N, 276G, 277R, 278I, 293L, 294Q, 295V, 296K, 307C, 309R, 311Y, 346V, 369R, 372D
CDD
cd05247 (UDP_G4E_1_SDR_e)

309R

substrate binding site
199T, 200C, 201A, 223Y, 252Y, 253F, 254N, 276G, 277R, 278I, 293L, 294Q, 295V, 296K, 307C, 309R, 311Y, 346V, 369R, 372D
CDD
cd05247 (UDP_G4E_1_SDR_e)

311Y

substrate binding site
199T, 200C, 201A, 223Y, 252Y, 253F, 254N, 276G, 277R, 278I, 293L, 294Q, 295V, 296K, 307C, 309R, 311Y, 346V, 369R, 372D
CDD
cd05247 (UDP_G4E_1_SDR_e)

346V

substrate binding site
199T, 200C, 201A, 223Y, 252Y, 253F, 254N, 276G, 277R, 278I, 293L, 294Q, 295V, 296K, 307C, 309R, 311Y, 346V, 369R, 372D
CDD
cd05247 (UDP_G4E_1_SDR_e)

369R

substrate binding site
199T, 200C, 201A, 223Y, 252Y, 253F, 254N, 276G, 277R, 278I, 293L, 294Q, 295V, 296K, 307C, 309R, 311Y, 346V, 369R, 372D
CDD
cd05247 (UDP_G4E_1_SDR_e)

372D

substrate binding site
199T, 200C, 201A, 223Y, 252Y, 253F, 254N, 276G, 277R, 278I, 293L, 294Q, 295V, 296K, 307C, 309R, 311Y, 346V, 369R, 372D
CDD
cd05247 (UDP_G4E_1_SDR_e)

GO term prediction

Biological Process

GO:0006012 galactose metabolic process

Molecular Function

GO:0003978 UDP-glucose 4-epimerase activity

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features