Mp8g03840.1

Protein

Length

1,331 amino acids

Protein family membership

None predicted.

Homologous superfamilies

Homologous superfamily
132 - 311
MyTH4 domain superfamily (IPR038185)
416 - 527
FERM/acyl-CoA-binding protein superfamily (IPR014352)
943 - 1,314
Kinesin motor domain superfamily (IPR036961)
Homologous superfamily
412 - 529
FERM superfamily, second domain (IPR035963)
532 - 639
PH-like domain superfamily (IPR011993)
889 - 972
Prismane-like superfamily (IPR011254)
Homologous superfamily
948 - 1,300
P-loop containing nucleoside triphosphate hydrolase (IPR027417)

1 200 400 600 800 1000 1200 1331

Domains and repeats

Domain
150 - 309
MyTH4 domain (IPR000857)
421 - 535
FERM central domain (IPR019748)
946 - 1,280
Kinesin motor domain (IPR001752)
Domain
312 - 534
Band 4.1 domain (IPR019749)
Domain
314 - 628
FERM domain (IPR000299)

1 200 400 600 800 1000 1200 1331

Detailed signature matches

IPR038185

MyTH4 domain superfamily
1. G3DSA:1.25.40...
  
  132 - 311
  
  GENE3D
  G3DSA:1.25.40.530 (G3DSA:1.25.40.530)
IPR035963

FERM superfamily, second domain
1. SSF47031 (Second do...)
  
  412 - 529
  
  SUPERFAMILY
  SSF47031 (Second domain of FERM)
IPR014352

FERM/acyl-CoA-binding protein superfamily
1. G3DSA:1.20.80.10
  
  416 - 527
  
  GENE3D
  G3DSA:1.20.80.10 (G3DSA:1.20.80.10)
IPR011993

PH-like domain superfamily
1. G3DSA:2.30.29.30
  
  532 - 639
  
  GENE3D
  G3DSA:2.30.29.30 (G3DSA:2.30.29.30)
IPR011254

Prismane-like superfamily
1. SSF56821 (Prismane ...)
  
  889 - 972
  
  SUPERFAMILY
  SSF56821 (Prismane protein-like)
IPR036961

Kinesin motor domain superfamily
1. G3DSA:3.40.85... (K...)
  
  943 - 1,314
  
  GENE3D
  G3DSA:3.40.850.10 (Kinesin)
IPR027417

P-loop containing nucleoside triphosphate hydrolase
1. SSF52540 (P-loop co...)
  
  948 - 1,300
  
  SUPERFAMILY
  SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
IPR000857

MyTH4 domain
1. SM00139 (MyTH4_1)
  
  150 - 309
  
  SMART
  SM00139 (MyTH4_1)
2. PS51016 (MYTH4)
  
  150 - 309
  
  PROSITE profiles
  PS51016 (MYTH4)
3. PF00784 (MyTH4)
  
  199 - 307
  
  Pfam
  PF00784 (MyTH4)
IPR019749

Band 4.1 domain
1. SM00295 (B41_5)
  
  312 - 534
  
  SMART
  SM00295 (B41_5)
IPR000299

FERM domain
1. PS50057 (FERM_3)
  
  314 - 628
  
  PROSITE profiles
  PS50057 (FERM_3)
IPR019748

FERM central domain
1. PF00373 (FERM_M)
  
  421 - 535
  
  Pfam
  PF00373 (FERM_M)
2. cd14473 (FERM_B-lobe)
  
  429 - 527
  
  CDD
  cd14473 (FERM_B-lobe)
IPR001752

Kinesin motor domain
1. PR00380 (KINESINHEAVY)
  
  1,019 - 1,040
  
  PRINTS
  PR00380 (KINESINHEAVY)
  
  1,173 - 1,191
  
  PRINTS
  PR00380 (KINESINHEAVY)
  
  1,142 - 1,159
  
  PRINTS
  PR00380 (KINESINHEAVY)
  
  1,222 - 1,243
  
  PRINTS
  PR00380 (KINESINHEAVY)
2. PF00225 (Kinesin)
  
  954 - 1,272
  
  Pfam
  PF00225 (Kinesin)
3. PS50067 (KINESIN_MO...)
  
  948 - 1,272
  
  PROSITE profiles
  PS50067 (KINESIN_MOTOR_2)
4. SM00129 (kinesin_4)
  
  946 - 1,280
  
  SMART
  SM00129 (kinesin_4)
IPR019821

Kinesin motor domain, conserved site
1. PS00411 (KINESIN_MO...)
  
  1,172 - 1,183
  
  PROSITE patterns
  PS00411 (KINESIN_MOTOR_1)

no IPR

Unintegrated signatures

G3DSA:3.10.20.90

313 - 415

GENE3D
G3DSA:3.10.20.90 (G3DSA:3.10.20.90)
PTHR47972 (KINESIN-...)

100 - 1,302

PANTHER
PTHR47972 (KINESIN-LIKE PROTEIN KLP-3)
PTHR47972:SF16 (KIN...)

100 - 1,302

PANTHER
PTHR47972:SF16 (KINESIN-LIKE PROTEIN)
SSF50729 (PH domain...)

534 - 622

SUPERFAMILY
SSF50729 (PH domain-like)
cd01366 (KISc_C_ter...)

946 - 1,274

CDD
cd01366 (KISc_C_terminal)
cd13200 (FERM_C_KCBP)

531 - 637

CDD
cd13200 (FERM_C_KCBP)

Other features

Coil

655 - 745

COILS
Coil (Coil)

841 - 875

COILS
Coil (Coil)

777 - 839

COILS
Coil (Coil)

886 - 913

COILS
Coil (Coil)
mobidb-lite (disord...)

1 - 73

MobiDB Lite
mobidb-lite (disorder_prediction)

1,298 - 1,331

MobiDB Lite
mobidb-lite (disorder_prediction)

744 - 789

MobiDB Lite
mobidb-lite (disorder_prediction)
mobidb-lite (Polyam...)

1,298 - 1,314

MobiDB Lite
mobidb-lite (disorder_prediction)
Feature: Polyampholyte

763 - 778

MobiDB Lite
mobidb-lite (disorder_prediction)
Feature: Polyampholyte
mobidb-lite (Polar)

1,315 - 1,331

MobiDB Lite
mobidb-lite (disorder_prediction)
Feature: Polar

1 - 30

MobiDB Lite
mobidb-lite (disorder_prediction)
Feature: Polar

52 - 73

MobiDB Lite
mobidb-lite (disorder_prediction)
Feature: Polar

748 - 762

MobiDB Lite
mobidb-lite (disorder_prediction)
Feature: Polar

Residue annotation

putative phosphoin...

539K

putative phosphoinositide binding site
539K, 562F, 564R, 570Y
CDD
cd13200 (FERM_C_KCBP)

562F

putative phosphoinositide binding site
539K, 562F, 564R, 570Y
CDD
cd13200 (FERM_C_KCBP)

564R

putative phosphoinositide binding site
539K, 562F, 564R, 570Y
CDD
cd13200 (FERM_C_KCBP)

570Y

putative phosphoinositide binding site
539K, 562F, 564R, 570Y
CDD
cd13200 (FERM_C_KCBP)
putative peptide b...

574A

putative peptide binding site
574A, 578D, 579I, 580M, 581Q, 625L, 629S, 632R, 633N
CDD
cd13200 (FERM_C_KCBP)

578D

putative peptide binding site
574A, 578D, 579I, 580M, 581Q, 625L, 629S, 632R, 633N
CDD
cd13200 (FERM_C_KCBP)

579I

putative peptide binding site
574A, 578D, 579I, 580M, 581Q, 625L, 629S, 632R, 633N
CDD
cd13200 (FERM_C_KCBP)

580M

putative peptide binding site
574A, 578D, 579I, 580M, 581Q, 625L, 629S, 632R, 633N
CDD
cd13200 (FERM_C_KCBP)

581Q

putative peptide binding site
574A, 578D, 579I, 580M, 581Q, 625L, 629S, 632R, 633N
CDD
cd13200 (FERM_C_KCBP)

625L

putative peptide binding site
574A, 578D, 579I, 580M, 581Q, 625L, 629S, 632R, 633N
CDD
cd13200 (FERM_C_KCBP)

629S

putative peptide binding site
574A, 578D, 579I, 580M, 581Q, 625L, 629S, 632R, 633N
CDD
cd13200 (FERM_C_KCBP)

632R

putative peptide binding site
574A, 578D, 579I, 580M, 581Q, 625L, 629S, 632R, 633N
CDD
cd13200 (FERM_C_KCBP)

633N

putative peptide binding site
574A, 578D, 579I, 580M, 581Q, 625L, 629S, 632R, 633N
CDD
cd13200 (FERM_C_KCBP)
putative actin bin...

625L

putative actin binding site 2
625L, 626R, 627R, 628Y, 629S, 630R, 631T, 632R, 633N, 634I, 635A, 636N
CDD
cd13200 (FERM_C_KCBP)

626R

putative actin binding site 2
625L, 626R, 627R, 628Y, 629S, 630R, 631T, 632R, 633N, 634I, 635A, 636N
CDD
cd13200 (FERM_C_KCBP)

627R

putative actin binding site 2
625L, 626R, 627R, 628Y, 629S, 630R, 631T, 632R, 633N, 634I, 635A, 636N
CDD
cd13200 (FERM_C_KCBP)

628Y

putative actin binding site 2
625L, 626R, 627R, 628Y, 629S, 630R, 631T, 632R, 633N, 634I, 635A, 636N
CDD
cd13200 (FERM_C_KCBP)

629S

putative actin binding site 2
625L, 626R, 627R, 628Y, 629S, 630R, 631T, 632R, 633N, 634I, 635A, 636N
CDD
cd13200 (FERM_C_KCBP)

630R

putative actin binding site 2
625L, 626R, 627R, 628Y, 629S, 630R, 631T, 632R, 633N, 634I, 635A, 636N
CDD
cd13200 (FERM_C_KCBP)

631T

putative actin binding site 2
625L, 626R, 627R, 628Y, 629S, 630R, 631T, 632R, 633N, 634I, 635A, 636N
CDD
cd13200 (FERM_C_KCBP)

632R

putative actin binding site 2
625L, 626R, 627R, 628Y, 629S, 630R, 631T, 632R, 633N, 634I, 635A, 636N
CDD
cd13200 (FERM_C_KCBP)

633N

putative actin binding site 2
625L, 626R, 627R, 628Y, 629S, 630R, 631T, 632R, 633N, 634I, 635A, 636N
CDD
cd13200 (FERM_C_KCBP)

634I

putative actin binding site 2
625L, 626R, 627R, 628Y, 629S, 630R, 631T, 632R, 633N, 634I, 635A, 636N
CDD
cd13200 (FERM_C_KCBP)

635A

putative actin binding site 2
625L, 626R, 627R, 628Y, 629S, 630R, 631T, 632R, 633N, 634I, 635A, 636N
CDD
cd13200 (FERM_C_KCBP)

636N

putative actin binding site 2
625L, 626R, 627R, 628Y, 629S, 630R, 631T, 632R, 633N, 634I, 635A, 636N
CDD
cd13200 (FERM_C_KCBP)
ATP binding site c...

956R

ATP binding site
956R, 1,028G, 1,031G, 1,033G, 1,034K, 1,035T, 1,036F, 1,178D
CDD
cd01366 (KISc_C_terminal)

1,028G

ATP binding site
956R, 1,028G, 1,031G, 1,033G, 1,034K, 1,035T, 1,036F, 1,178D
CDD
cd01366 (KISc_C_terminal)

1,031G

ATP binding site
956R, 1,028G, 1,031G, 1,033G, 1,034K, 1,035T, 1,036F, 1,178D
CDD
cd01366 (KISc_C_terminal)

1,033G

ATP binding site
956R, 1,028G, 1,031G, 1,033G, 1,034K, 1,035T, 1,036F, 1,178D
CDD
cd01366 (KISc_C_terminal)

1,034K

ATP binding site
956R, 1,028G, 1,031G, 1,033G, 1,034K, 1,035T, 1,036F, 1,178D
CDD
cd01366 (KISc_C_terminal)

1,035T

ATP binding site
956R, 1,028G, 1,031G, 1,033G, 1,034K, 1,035T, 1,036F, 1,178D
CDD
cd01366 (KISc_C_terminal)

1,036F

ATP binding site
956R, 1,028G, 1,031G, 1,033G, 1,034K, 1,035T, 1,036F, 1,178D
CDD
cd01366 (KISc_C_terminal)

1,178D

ATP binding site
956R, 1,028G, 1,031G, 1,033G, 1,034K, 1,035T, 1,036F, 1,178D
CDD
cd01366 (KISc_C_terminal)
microtubule intera...

1,225R

microtubule interaction site
1,225R, 1,228K, 1,231M
CDD
cd01366 (KISc_C_terminal)

1,228K

microtubule interaction site
1,225R, 1,228K, 1,231M
CDD
cd01366 (KISc_C_terminal)

1,231M

microtubule interaction site
1,225R, 1,228K, 1,231M
CDD
cd01366 (KISc_C_terminal)

GO term prediction

Biological Process

GO:0007018 microtubule-based movement
GO:0055114 oxidation-reduction process

Molecular Function

GO:0003777 microtubule motor activity
GO:0003824 catalytic activity
GO:0005524 ATP binding
GO:0008017 microtubule binding
GO:0016491 oxidoreductase activity
GO:1990939 ATP-dependent microtubule motor activity

Cellular Component

GO:0005856 cytoskeleton

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Entry type

Status

Per-residue features