Mp3g13250



Description

Annotation

Database ID Description
CDD cd03506 Delta6-FADS-like
Pfam PF00173 Cytochrome b5-like Heme/Steroid binding domain
SUPERFAMILY SSF55856 Cytochrome b5-like heme/steroid binding domain
Pfam PF00487 Fatty acid desaturase
PIRSF PIRSF015921 FA_sphingolip_des
Gene3D G3DSA:3.10.120.10 -
SMART SM01117 Cyt_b5_2
PANTHER PTHR19353 FATTY ACID DESATURASE 2
FunFam G3DSA:3.10.120.10:FF:000007 Sulfite oxidase, mitochondrial
ProSiteProfiles PS50255 Cytochrome b5 family, heme-binding domain profile.
KEGG K00508 linoleoyl-CoA desaturase [EC:1.14.19.3]
KOG KOG4232 Delta 6-fatty acid desaturase/delta-8 sphingolipid desaturase; [I]
MapolyID Mapoly0050s0117 -
GO GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
GO GO:0016491 oxidoreductase activity
GO GO:0016020 membrane
GO GO:0006629 lipid metabolic process

Nomenclature

Gene symbol Product Transcript ID Status
MpDES5 Δ5 fatty acid desaturase Published
MpFAD7 Secondary metabolism enzyme Provisional
This is a provisional entry. If you want to update the entry, please contact the administrator.

Associated Literature (AI-based literature mining, Beta-version)

Δ5 fatty acid desaturase; MpDES5 mediates two Δ5-desaturation reactions, dihomo-γ-linolenic acid (DGLA; 20:3Δ8,11,14) to arachidonic acid (AA;20:4Δ5,8,11,14) in the n-6 pathway, and eicosatetraenoic acid (ETA; 18:4Δ8,11,14,17) to eicosapentaenoic acid (EPA; 20:5Δ5,8,11,14,17) in the n-3 pathway. (from nomenclature)

2 core 1 peripheral

Kneeshaw, S., et al. (2022) · PNAS  research experimental subject
Desaturase converting eicosatetraenoic acid (ETA) into EPA. Mpdes5 mutants were analyzed for EPA/ETA production and downstream jasmonate biosynthesis.
Kajikawa M, Yamato KT, Kohzu Y, Nojiri M, Sakuradani E, Shimizu S, Sakai Y, Fukuzawa H, Ohyama K. (2004) · Plant Mol Biol  research experimental subject
Delta-5-desaturase cDNA isolated and characterized; together with MpDES6 and MpELO1 reconstituted arachidonic/eicosapentaenoic acid synthesis in yeast.
Resemann, H. C., et al. (2021) · Nature Plants  research sequence comparator
Delta-5 sphingolipid desaturase of M. polymorpha; used as a reference sequence in a phylogenetic study of sphingolipid-desaturase convergence across land plants.

Transcript models

Transcript ID Location Sequences Extract region
Mp3g13250.1 chr3:13799574..13804599 (+) Gene /  mRNA /  CDS /  Protein
FASTA / GenBank (with flanking bases)

Expression Level powered by MBEX

Link to the original image in MBEX

Single-cell expression scRNA-seq atlas from Wang et al., 2023

Expression of Mp3g13250 across the single-cell RNA-seq atlas. Cluster identities (right) annotate the same UMAP used for the feature plot (left).

Feature plot of Mp3g13250 on UMAP
Feature plot (Seurat scale expression level).
UMAP cluster annotation
Cell-type annotation of the UMAP clusters.
Violin plot by developmental stage
Violin plot by stage. Expression across developmental time points (D0–D31).
Violin plot by cell cluster
Violin plot by cluster. Expression across cell clusters (1–21).

Gene structure:

Sequences:

Gene UTR + CDS + intron

FASTA

mRNA UTR + CDS

FASTA

CDS

FASTA

Protein

FASTA

MarpolBase / Genome Informatics Lab. NIG.