Mp4g22640
Description
Annotation
| Database | ID | Description |
|---|---|---|
| FunFam | G3DSA:3.40.47.10:FF:000008 | 3-hydroxy-3-methylglutaryl coenzyme A synthase |
| Pfam | PF08540 | Hydroxymethylglutaryl-coenzyme A synthase C terminal |
| ProSitePatterns | PS01226 | Hydroxymethylglutaryl-coenzyme A synthase active site. |
| Gene3D | G3DSA:3.40.47.10 | - |
| PANTHER | PTHR43323 | 3-HYDROXY-3-METHYLGLUTARYL COENZYME A SYNTHASE |
| CDD | cd00827 | init_cond_enzymes |
| Pfam | PF01154 | Hydroxymethylglutaryl-coenzyme A synthase N terminal |
| SUPERFAMILY | SSF53901 | Thiolase-like |
| NCBIfam | TIGR01833 | hydroxymethylglutaryl-CoA synthase |
| KEGG | K01641 | hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10] |
| KOG | KOG1393 | Hydroxymethylglutaryl-CoA synthase; [I] |
| MapolyID | Mapoly0020s0034 | - |
| GO | GO:0008299 | isoprenoid biosynthetic process |
| GO | GO:0006084 | acetyl-CoA metabolic process |
| GO | GO:0004421 | hydroxymethylglutaryl-CoA synthase activity |
| GO | GO:0016746 | acyltransferase activity |
| GO | GO:0010142 | farnesyl diphosphate biosynthetic process, mevalonate pathway |
Nomenclature
| Gene symbol | Product | Transcript ID | Status |
|---|---|---|---|
| MpHMGS | Secondary metabolism enzyme, Terpene biosynthesis enzymes | Provisional |
Associated Literature (AI-based literature mining, Beta-version)
Secondary metabolism enzyme, Terpene biosynthesis enzymes (from nomenclature)
0 core 1 peripheral
Forestier ECF, Asprilla P, Bonter I, Romani F, Frangedakis E, Haseloff J. (2026)
· Communications biology research sequence background
MVA pathway enzyme listed among annotated terpene biosynthesis genes; not experimentally characterized here.
Single-cell expression scRNA-seq atlas from Wang et al., 2023
Expression of Mp4g22640 across the single-cell RNA-seq atlas. Cluster identities (right) annotate the same UMAP used for the feature plot (left).
Gene structure:
Sequences: |
Gene UTR + CDS + intron |
| >Mp4g22640.1 CTGTATCTGT AGTCACCATT CCTACTACGT CGGGTCAGTT CTTGACGGGC AAAGACGGCA GGTCGGTTTC AGCACCGCTC CACAAACGAG GAGACTGACG GATCTACGAC GGTTCGGGCT AACAATACAC TGTACTTCGC AGAAGACACC ACAAAAGCGG GAACCTCTGA GCGACAGTTG GGGCCAGGGC GGGCCCCACT CGGCGCCCGT CTTCGTCGCC CCATCTCCAG TGCTAAAACC GGCCTCTTGT CCGAGCCGCG TCCGGGATGA GAACGAGCGC CATCGCCCAG CCGCAAAGAC GACCCGAATG CGGAGAAACA CTCCCGCAAG GGCGGATCGA CGGCCGGTCG GAAACCTACG CGGTCGACGG CACGATGGCG AAGGAAGGCA GGAATGCAGG CAGGCAGGCT GGCTGCCTGG CTGCCTACGA AGGTAGCTCG TGCGTGGTCT GCTGGATGAG CTGTGATGAG CTAGCTCGCC CTCGTTTCTT TACTGCAGTA CTCGTGGAGC CGGAGGATCT CGGCCGGGGC ATCGAGAGCG GGCGGGTCGA AATCCGTCGA TCGTCCGCTT CTGCGTGCTC ATGGCCTGCC GTGCTCTGCA GTGATGGACA CGATCCCCCT CCGAACTCGT AGCCCCTGTC CGCTTTTATA AAAGCCATCA AGAGCGCCAC TTCCTCATTC TTCTTCGTTC AAAGTTTGAG CGAGCGAAGA AGAGTTGCGC CGAGAATCGG AGTCCGTGAG TCGGTCGGTA CTTTGGAGCC CAGGGTTTCA GAGAGTCATC AGAAATCATC ATCGAGTGCT ACTACCAGTT CGGGTTGATT TTTCTCGTTC GTGCGCGATC CCGGTTTGGT GATTCTCATC TCTGTAGTCG TTCGCGGGGT GAGGGATTGG AATCATGGCC TGTCCACGCC CAGAGAATGT CGGTATTTTG GCCGTGGAGA TGTATTTCCC CACGAGCTAT GTTTCGCAGG AAGAATTGGA GGTTCACGAC GGGGTTAGCA AGGGCAAGTA CACGATCGGG TTAGGGCAGG ACAAGCTGGG GTTTTGCACA GATTGCGAAG ATGTGATCTC CATGAGCTTG ACCGTGGTCA AGTCTCTGAT GGAGAAGTAT GGAGTGTCAC CGAATTCCAT CGGGCGCCTC GAGGTCGGCA GTGAGACTGT CATCGATAAG AGTAAGTCCA TCAAGACCAA TCTGATGGAG CTTTTCGAGG AGAGCGGAAA TGGTGATGTC GAAGGCGTGG ATTCCACGAA TGCGTGCTAC GGTGGAACCG CAGCTCTGTT CAACTGCATC AATTGGGTCG AGAGCACCGG CTGGGATGGG CGATTCGGGC TCGTCGTCGC CGCCGATGTT GCGGTTTACG CCGAGGGCCC TGCCAGACCC ACCGGAGGCG CCGGAGCCGT GGCAATGTTG ATTGGGCCGA ATGCCCCATT CGTGATGGAG CGCAGCTACA CTTCGAGTCA AATGTCGCAC GCTTACGATT TTTACAAGCC CGTGCTGGCC AGCGAATACC CTGTCGTGGA TGGGAAGCTG TCCACGACTT GCTACCTGAA GGCCCTCGAC CTCTGCTACC GTCGTTTCTG CGACAAGTAT TCGAAGAAGG AAGGCCAACC CTTTTCGCTC GCTGACATCG ATTACGTCGT CTGCCATTCG CCATACAACA AGCTCGTCCA GAAGAGTTTT GCCCGCCTCG TGTACAACGA CTACTTGCAA AGCCCCAATC TGGTGGGCGA GGAAGTTGCT GCCAAGTTGG AGCCGTTCGC TCATCTCTCG CACGACGACA GTCTTGTGAA TCGCGATCTC GAGAAGCTCG CTCAGCAGGT AGCGAAGCCT CAGTACGACG AGAAGGTAGG GCCGACGACC CTCCTGCCCA AAGTGGTGGG CAACATGTAC TGCGCAGCAT TATACGGAGG CCTCGTGACT CTCATCCACA ACAAGGCCGA GTCCCTGGTC GGTAAAAGAC TGGTATTCTT CTCTTACGGT AGTGGACTGG CGTCGTCTAT GTTCTCTTTC CGAGTTAGGG CAGTCGAATC TCCATTCAGC TTATCGGCGA TCGCAGAAGC TCTGGACATT ACGAGCAAGC TCGAATCTAG GATCGAGGTC ACCCCGGAGA AGTTTGGGAA GGCTATGCAT CTCGGGGAAA CTCGCTACGG AGCTAACGAT TACATTCCCA CCAGCTCGAT CAAGGAATTG CGCGCTGGAA CGTTCTACCT CACCAAAGTA GATGACAAGT ACCGCAGGTT TTACTCTAGA AAGCCGAGCG TAGAATCATC TCCCGCGATG AATGGAGGTC TCGTAGCGTA GTCTGATGAT GGGAAAGCCC ATTGAAAATA AAATGTACAA AAATTTATTC TTACTGGAAA ATCTGTCGTC AAGATTTCGT ATCTTTCCAT CCTTTCCGAG CAGGTTTCGA ATTGCATGTG TGCTTGATTG CTGTTGGACT TACTTCCTCT GCGGTCTCAC AGTATCGATG AATCCTGTTT CTCAAGGTCC GAATGTTCAA ATTTCGGTCC TGGTCCTGCC GATTTCAGAA GTTTCGAAGC AGTGATCTAC CAAGCACATG ATTCTGGCCC AGTGAATAGG ACCCTGGCAT GCTGATTCCT TTTACTCCAG TTAAGATTGG TCGTATTCGT TCGGAGGATA TTCGACATCG ACTCTCAGTT TTCCTCTGTG CTCGCTTCGA CGTTGGAGAA AATGGGATGC CGGCAGAGTA TCCAAAGGGA GGGTGGGAGT GTGGGAGTGA GGGAGGGTCA TACTCTGTCC CCGAGAGCAA CGGATCACGA TGGACGAAAG AGGAGGCTGA ACTTCGCTGC CGAAAAGGGG ACAGGAACGG ACCTGTCATC GTCTCAGGGC GGAAACAACT GCTGTCAGTC CGAGTGAGCG CAACAGGGAA TGGCGACATT ACAGATTCAA AACCTCCTGC AGCCCATCAC TCTCACGAGT CTATGTGCAT GGATAAATAC CGGTTGGGTC GTACGACGGC GCGATGGAGC GAAAGAGTAA TCACCGGGAT CAAAAGCAGA GGCGAAATGC CATCGACGAC GAGTGCCGGT GGAATGATTG ATCGACTGCA GATGATTTTT GTAGTCACAA GAACGGAGGA AGAGGGTACA AGGACCAAGA CCGAGCCCCG GCTCTCCC |
mRNA UTR + CDS |
| >Mp4g22640.1 CTGTATCTGT AGTCACCATT CCTACTACGT CGGGTCAGTT CTTGACGGGC AAAGACGGCA GGTCGGTTTC AGCACCGCTC CACAAACGAG GAGACTGACG GATCTACGAC GGTTCGGGCT AACAATACAC TGTACTTCGC AGAAGACACC ACAAAAGCGG GAACCTCTGA GCGACAGTTG GGGCCAGGGC GGGCCCCACT CGGCGCCCGT CTTCGTCGCC CCATCTCCAG TGCTAAAACC GGCCTCTTGT CCGAGCCGCG TCCGGGATGA GAACGAGCGC CATCGCCCAG CCGCAAAGAC GACCCGAATG CGGAGAAACA CTCCCGCAAG GGCGGATCGA CGGCCGGTCG GAAACCTACG CGGTCGACGG CACGATGGCG AAGGAAGGCA GGAATGCAGG CAGGCAGGCT GGCTGCCTGG CTGCCTACGA AGGTAGCTCG TGCGTGGTCT GCTGGATGAG CTGTGATGAG CTAGCTCGCC CTCGTTTCTT TACTGCAGTA CTCGTGGAGC CGGAGGATCT CGGCCGGGGC ATCGAGAGCG GGCGGGTCGA AATCCGTCGA TCGTCCGCTT CTGCGTGCTC ATGGCCTGCC GTGCTCTGCA GTGATGGACA CGATCCCCCT CCGAACTCGT AGCCCCTGTC CGCTTTTATA AAAGCCATCA AGAGCGCCAC TTCCTCATTC TTCTTCGTTC AAAGTTTGAG CGAGCGAAGA AGAGTTGCGC CGAGAATCGG AGTCCGTGAG TCGGTCGGTA CTTTGGAGCC CAGGGTTTCA GAGAGTCATC AGAAATCATC ATCGAGTGCT ACTACCAGTT CGGGTTGATT TTTCTCGTTC GTGCGCGATC CCGGTTTGGT GATTCTCATC TCTGTAGTCG TTCGCGGGGT GAGGGATTGG AATCATGGCC TGTCCACGCC CAGAGAATGT CGGTATTTTG GCCGTGGAGA TGTATTTCCC CACGAGCTAT GTTTCGCAGG AAGAATTGGA GGTTCACGAC GGGGTTAGCA AGGGCAAGTA CACGATCGGG TTAGGGCAGG ACAAGCTGGG GTTTTGCACA GATTGCGAAG ATGTGATCTC CATGAGCTTG ACCGTGGTCA AGTCTCTGAT GGAGAAGTAT GGAGTGTCAC CGAATTCCAT CGGGCGCCTC GAGGTCGGCA GTGAGACTGT CATCGATAAG AGTAAGTCCA TCAAGACCAA TCTGATGGAG CTTTTCGAGG AGAGCGGAAA TGGTGATGTC GAAGGCGTGG ATTCCACGAA TGCGTGCTAC GGTGGAACCG CAGCTCTGTT CAACTGCATC AATTGGGTCG AGAGCACCGG CTGGGATGGG CGATTCGGGC TCGTCGTCGC CGCCGATGTT GCGGTTTACG CCGAGGGCCC TGCCAGACCC ACCGGAGGCG CCGGAGCCGT GGCAATGTTG ATTGGGCCGA ATGCCCCATT CGTGATGGAG CGCAGCTACA CTTCGAGTCA AATGTCGCAC GCTTACGATT TTTACAAGCC CGTGCTGGCC AGCGAATACC CTGTCGTGGA TGGGAAGCTG TCCACGACTT GCTACCTGAA GGCCCTCGAC CTCTGCTACC GTCGTTTCTG CGACAAGTAT TCGAAGAAGG AAGGCCAACC CTTTTCGCTC GCTGACATCG ATTACGTCGT CTGCCATTCG CCATACAACA AGCTCGTCCA GAAGAGTTTT GCCCGCCTCG TGTACAACGA CTACTTGCAA AGCCCCAATC TGGTGGGCGA GGAAGTTGCT GCCAAGTTGG AGCCGTTCGC TCATCTCTCG CACGACGACA GTCTTGTGAA TCGCGATCTC GAGAAGCTCG CTCAGCAGGT AGCGAAGCCT CAGTACGACG AGAAGGTAGG GCCGACGACC CTCCTGCCCA AAGTGGTGGG CAACATGTAC TGCGCAGCAT TATACGGAGG CCTCGTGACT CTCATCCACA ACAAGGCCGA GTCCCTGGTC GGTAAAAGAC TGGTATTCTT CTCTTACGGT AGTGGACTGG CGTCGTCTAT GTTCTCTTTC CGAGTTAGGG CAGTCGAATC TCCATTCAGC TTATCGGCGA TCGCAGAAGC TCTGGACATT ACGAGCAAGC TCGAATCTAG GATCGAGGTC ACCCCGGAGA AGTTTGGGAA GGCTATGCAT CTCGGGGAAA CTCGCTACGG AGCTAACGAT TACATTCCCA CCAGCTCGAT CAAGGAATTG CGCGCTGGAA CGTTCTACCT CACCAAAGTA GATGACAAGT ACCGCAGGTT TTACTCTAGA AAGCCGAGCG TAGAATCATC TCCCGCGATG AATGGAGGTC TCGTAGCGTA GTCTGATGAT GGGAAAGCCC ATTGAAAATA AAATGTACAA AAATTTATTC TTACTGGAAA ATCTGTCGTC AAGATTTCGT ATCTTTCCAT CCTTTCCGAG CAGGTTTCGA ATTGCATGTG TGCTTGATTG CTGTTGGACT TACTTCCTCT GCGGTCTCAC AGTATCGATG AATCCTGTTT CTCAAGGTCC GAATGTTCAA ATTTCGGTCC TGGTCCTGCC GATTTCAGAA GTTTCGAAGC AGTGATCTAC CAAGCACATG ATTCTGGCCC AGTGAATAGG ACCCTGGCAT GCTGATTCCT TTTACTCCAG TTAAGATTGG TCGTATTCGT TCGGAGGATA TTCGACATCG ACTCTCAGTT TTCCTCTGTG CTCGCTTCGA CGTTGGAGAA AATGGGATGC CGGCAGAGTA TCCAAAGGGA GGGTGGGAGT GTGGGAGTGA GGGAGGGTCA TACTCTGTCC CCGAGAGCAA CGGATCACGA TGGACGAAAG AGGAGGCTGA ACTTCGCTGC CGAAAAGGGG ACAGGAACGG ACCTGTCATC GTCTCAGGGC GGAAACAACT GCTGTCAGTC CGAGTGAGCG CAACAGGGAA TGGCGACATT ACAGATTCAA AACCTCCTGC AGCCCATCAC TCTCACGAGT CTATGTGCAT GGATAAATAC CGGTTGGGTC GTACGACGGC GCGATGGAGC GAAAGAGTAA TCACCGGGAT CAAAAGCAGA GGCGAAATGC CATCGACGAC GAGTGCCGGT GGAATGATTG ATCGACTGCA GATGATTTTT GTAGTCACAA GAACGGAGGA AGAGGGTACA AGGACCAAGA CCGAGCCCCG GCTCTCCC |
CDS |
| >Mp4g22640.1 ATGGCCTGTC CACGCCCAGA GAATGTCGGT ATTTTGGCCG TGGAGATGTA TTTCCCCACG AGCTATGTTT CGCAGGAAGA ATTGGAGGTT CACGACGGGG TTAGCAAGGG CAAGTACACG ATCGGGTTAG GGCAGGACAA GCTGGGGTTT TGCACAGATT GCGAAGATGT GATCTCCATG AGCTTGACCG TGGTCAAGTC TCTGATGGAG AAGTATGGAG TGTCACCGAA TTCCATCGGG CGCCTCGAGG TCGGCAGTGA GACTGTCATC GATAAGAGTA AGTCCATCAA GACCAATCTG ATGGAGCTTT TCGAGGAGAG CGGAAATGGT GATGTCGAAG GCGTGGATTC CACGAATGCG TGCTACGGTG GAACCGCAGC TCTGTTCAAC TGCATCAATT GGGTCGAGAG CACCGGCTGG GATGGGCGAT TCGGGCTCGT CGTCGCCGCC GATGTTGCGG TTTACGCCGA GGGCCCTGCC AGACCCACCG GAGGCGCCGG AGCCGTGGCA ATGTTGATTG GGCCGAATGC CCCATTCGTG ATGGAGCGCA GCTACACTTC GAGTCAAATG TCGCACGCTT ACGATTTTTA CAAGCCCGTG CTGGCCAGCG AATACCCTGT CGTGGATGGG AAGCTGTCCA CGACTTGCTA CCTGAAGGCC CTCGACCTCT GCTACCGTCG TTTCTGCGAC AAGTATTCGA AGAAGGAAGG CCAACCCTTT TCGCTCGCTG ACATCGATTA CGTCGTCTGC CATTCGCCAT ACAACAAGCT CGTCCAGAAG AGTTTTGCCC GCCTCGTGTA CAACGACTAC TTGCAAAGCC CCAATCTGGT GGGCGAGGAA GTTGCTGCCA AGTTGGAGCC GTTCGCTCAT CTCTCGCACG ACGACAGTCT TGTGAATCGC GATCTCGAGA AGCTCGCTCA GCAGGTAGCG AAGCCTCAGT ACGACGAGAA GGTAGGGCCG ACGACCCTCC TGCCCAAAGT GGTGGGCAAC ATGTACTGCG CAGCATTATA CGGAGGCCTC GTGACTCTCA TCCACAACAA GGCCGAGTCC CTGGTCGGTA AAAGACTGGT ATTCTTCTCT TACGGTAGTG GACTGGCGTC GTCTATGTTC TCTTTCCGAG TTAGGGCAGT CGAATCTCCA TTCAGCTTAT CGGCGATCGC AGAAGCTCTG GACATTACGA GCAAGCTCGA ATCTAGGATC GAGGTCACCC CGGAGAAGTT TGGGAAGGCT ATGCATCTCG GGGAAACTCG CTACGGAGCT AACGATTACA TTCCCACCAG CTCGATCAAG GAATTGCGCG CTGGAACGTT CTACCTCACC AAAGTAGATG ACAAGTACCG CAGGTTTTAC TCTAGAAAGC CGAGCGTAGA ATCATCTCCC GCGATGAATG GAGGTCTCGT AGCGTAG |
Protein |
| >Mp4g22640.1 MACPRPENVG ILAVEMYFPT SYVSQEELEV HDGVSKGKYT IGLGQDKLGF CTDCEDVISM SLTVVKSLME KYGVSPNSIG RLEVGSETVI DKSKSIKTNL MELFEESGNG DVEGVDSTNA CYGGTAALFN CINWVESTGW DGRFGLVVAA DVAVYAEGPA RPTGGAGAVA MLIGPNAPFV MERSYTSSQM SHAYDFYKPV LASEYPVVDG KLSTTCYLKA LDLCYRRFCD KYSKKEGQPF SLADIDYVVC HSPYNKLVQK SFARLVYNDY LQSPNLVGEE VAAKLEPFAH LSHDDSLVNR DLEKLAQQVA KPQYDEKVGP TTLLPKVVGN MYCAALYGGL VTLIHNKAES LVGKRLVFFS YGSGLASSMF SFRVRAVESP FSLSAIAEAL DITSKLESRI EVTPEKFGKA MHLGETRYGA NDYIPTSSIK ELRAGTFYLT KVDDKYRRFY SRKPSVESSP AMNGGLVA |