Mp5g01600



Description

Annotation

Database ID Description
PANTHER PTHR11850 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS
Pfam PF05920 Homeobox KN domain
SMART SM00389 HOX_1
Gene3D G3DSA:1.10.10.60 -
SUPERFAMILY SSF46689 Homeodomain-like
CDD cd00086 homeodomain
ProSiteProfiles PS50071 'Homeobox' domain profile.
Coils Coil Coil
KOG KOG0773 Transcription factor MEIS1 and related HOX domain proteins; [K]
MapolyID Mapoly0175s0020 -
GO GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO GO:0006357 regulation of transcription by RNA polymerase II
GO GO:0003677 DNA binding
GO GO:0006355 regulation of DNA-templated transcription
GO GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific

Nomenclature

Gene symbol Product Transcript ID Status
MpHD20 transcription factor, HD, homeodomain protein Published
MpKNOX1 transcription factor, HD, homeodomain protein Published

Associated Literature (AI-based literature mining, Beta-version)

Egg-specific KNOX transcription factor that is the central subject; Mpknox1 loss-of-function eggs arrest at karyogamy (100% fail nuclear fusion). Maternally inherited and dispensable from the paternal side; MpKNOX1-GFP transiently localizes to both pronuclei ~12 h after fertilization to drive zygote activation.

2 core 7 peripheral

Dierschke, T., et al. (2021) · eLife  research experimental subject
Maternal (egg-expressed) TALE-KNOX gene that is essential for the haploid-to-diploid transition; loss-of-function alleles cause zygotic arrest and fail to activate the sporophyte program.
Hisanaga, T., et al. (2021) · eLife  research experimental subject
Egg-specific KNOX transcription factor that is the central subject; Mpknox1 loss-of-function eggs arrest at karyogamy (100% fail nuclear fusion). Maternally inherited and dispensable from the paternal side; MpKNOX1-GFP transiently localizes to both pronuclei ~12 h after fertilization to drive zygote activation.
Levins, J., et al. (2025) · New Phytologist 10.1111/nph.20454  research citation comparator
Cited as the Marchantia KNOX1 gene required to initiate diploid sporophyte development; used as comparator for ortholog presence in Riccia.
Kajiwara, T., et al. (2024) · Plant & Cell Physiology  research citation comparator
Sense-strand gene predominantly expressed in female gametes, cited as the putative target of SUK1 antisense regulation.
Bowman, J. L. (2022b) · Nature Plants  research citation background
Review: expressed in the egg cell; female Mpknox1 mutants arrest as fertilized zygotes.

Transcript models

Transcript ID Location Sequences Extract region
Mp5g01600.1 chr5:2886015..2890921 (-) Gene /  mRNA /  CDS /  Protein
FASTA / GenBank (with flanking bases)

Expression Level powered by MBEX

Link to the original image in MBEX

Single-cell expression scRNA-seq atlas from Wang et al., 2023

Expression of Mp5g01600 across the single-cell RNA-seq atlas. Cluster identities (right) annotate the same UMAP used for the feature plot (left).

Feature plot of Mp5g01600 on UMAP
Feature plot (Seurat scale expression level).
UMAP cluster annotation
Cell-type annotation of the UMAP clusters.
Violin plot by developmental stage
Violin plot by stage. Expression across developmental time points (D0–D31).
Violin plot by cell cluster
Violin plot by cluster. Expression across cell clusters (1–21).

Gene structure:

Sequences:

Gene UTR + CDS + intron

FASTA

mRNA UTR + CDS

FASTA

CDS

FASTA

Protein

FASTA


MarpolBase / Genome Informatics Lab. NIG.