Mp5g09290
Description
Annotation
| Database | ID | Description |
|---|---|---|
| Coils | Coil | Coil |
| PANTHER | PTHR23068 | DNA CYTOSINE-5- -METHYLTRANSFERASE 3-RELATED |
| Gene3D | G3DSA:3.40.50.150 | Vaccinia Virus protein VP39 |
| SUPERFAMILY | SSF53335 | S-adenosyl-L-methionine-dependent methyltransferases |
| ProSitePatterns | PS00094 | C-5 cytosine-specific DNA methylases active site. |
| MobiDBLite | mobidb-lite | consensus disorder prediction |
| Pfam | PF11926 | Domain of unknown function (DUF3444) |
| Pfam | PF00145 | C-5 cytosine-specific DNA methylase |
| ProSiteProfiles | PS51679 | C-5 cytosine-specific DNA methylase (Dnmt) domain profile. |
| KOG | KOG0919 | C-5 cytosine-specific DNA methylase; [K] |
| MapolyID | Mapoly0095s0030 | - |
| GO | GO:0008168 | methyltransferase activity |
| GO | GO:0005634 | nucleus |
Nomenclature
| Gene symbol | Product | Transcript ID | Status |
|---|---|---|---|
| MpDNMT3b | C-5 cytosine-specific DNA methylase | Published |
Associated Literature (AI-based literature mining, Beta-version)
C-5 cytosine-specific DNA methylase (from nomenclature)
0 core 1 peripheral
Walker, J., et al. (2025)
· Cell 188: doi: 10.1016/j.cell.2025.1003.1014 research experimental comparator
DNMT3-type (5mC) methyltransferase (Mp5g09290); compared to the N4C system.
Single-cell expression scRNA-seq atlas from Wang et al., 2023
Expression of Mp5g09290 across the single-cell RNA-seq atlas. Cluster identities (right) annotate the same UMAP used for the feature plot (left).
Gene structure:
Sequences: |
Gene UTR + CDS + intron |
| >Mp5g09290.1 GTCTGCGGGG AGAGATGGCC CGCTGGGTCC TCCGAATGAT TGTTGGGGAC TTTGTGTAGA GATGGGGTTC GTGACAGTGG AAACTGCAAA TTGCGTCCGC TCCTCTCGCA GCTTATGTCG ATCGGCGGGG TTGATTTCGC GCAGTCTGCA AGATGGGGTC GAAGCATCCT GCCATGGGTA CCACGATTTC CGACGATAGA ATCGATGGTC GAGAAGAGTC GATGTTCAAT TCGGTTAGAG GTAGTCTGAA AGGTGGCGCT AACCGGATGC AGCAAAGCCG ACCTGGACTC GGACAGCGTA GTCCAGATTG TGGGCTTCAG GAACCTTATT CCGGTGCGAA AGTTGTTGAC TAAGCTGCAT CATGCTCTAC TGAAGTTCGG TCATCGAGAA GCTCTTCCAT CCTCAACATG GACAAAGTCC TAAATCACAT AAGGAATCTC CGAGCCGAAG CTGAATCTTT GCTGAAAAAC GGGAACCGTC ATGATGGCGA TGACGAAGCT CACTGTGGCG TTGAGAAATC AATAGACTGC TCGAATTGCG GGGGTGACAG GTGGGTATTA AAACTTAGAC AAAAGGCCGG TTTCTGGAGG AGCAAACCTT TGGTGGTTCT CAGCTTATTC GATGGCATCG GTGGAGTGTG GGCGGCTCTC GAGAATCTTG GCATTCCTTT TATCGGGTAC AGCTGTGAGG TGAACGCCGA TGCGATGAAA GTGACCCAGC GAAATTACTG CTCTGTTCGT CATTTGGGAG ATATCCATCG ACTGAAAAAA GCAGACATAA AAGAGAAGAT AGACCTTGTT GTGGGTGGAT TTCCTTGTCA GGACTTGTCC TCCATGGGAG CGAGACTGGG GCTACACGGA AGTCGAAGCC GACTTTTCTT TGAAATGCTA CGAGTCATTA AAACATTCAG CCCAACATGG TTCGTTTTTC ACGCGTCCAG CTTCGATGCA TTTTTTGACT GTATGCATCT GACTCAACTG GACAGATAAT CTGAAATCGA TCTTCGGCAT GTATCCAAGA AAATGACGGC CTCCTTTACT CGGCTGCATT GCAGGTTTCT TGCGGAAAAT GTAGCCTCTA TGAGTTGGGT GGATCGCGAA GAAATCTCAA AGCATCTGAG TACCACTCCC TTGGAGATCG ATTCTCAGAA CTTCAGCCCT TGTAAACGGA GGCGCCTGTA CTGGTCAAAC ATACCCTATC CTAAGACCTG TCCCCGCATC GGAGATAATG AGGCAACCTC TATCCAGAGC GTCGTTCAAG GGGGCGCTTC TCTGGCGAAG AAAAACATGT GTGTATTATC CTCAAATGGT CTACAGGGTG CAACTAAAGC CCTGATGGAA CTAGTGTACG ACTTTCGTAT CGACAAGCCT CGCTACATCA ACGTGGTGGA AGTAGAACAA ATGATGGGAT ACCCCCCGCA CTACACCAAC GTGAAGTTTG ATGATCAGAA ACCGAAGGCA AAAATTCAGA GGCGTCGAGA GACCGAAATT AAGGAGGGAG GGGTTGACCG AAACACCAGA TGGCGGCTAT TGGGCAACTC GTTCTCAGTT CCGGTGATAT CGTTTCTCTT GAGCCCCCTG TTAGATGCTG ACATCCGAGA TCAGACCAGG AAATACCATC TTCCAGCGTC GGTTCGGGAG GCAGACTGCT CCGTCATGTC TCCAGGCGAG GTGAACTTCC AAACGAAATT TGTTCTTCAT TGAAGAGACT ACAAGTTAGA GCAGTGGAGA ACATCCAGTG AGGACATAGG ATCGAATCAG AAGGTCACGA AGTTCTCGAG AAAGGCTGAA ATCCATCATC GTTAATTAGC ATGGCAATGC TGTCTAAATC TTAGGGGCAG AGCAGAGTCT TCAGACGCTA ATTGGTCACG TATTGTTGCG AATCGCCTTC GAGAAGGCCG GATCGGAACT CATCTTCTAA GCTCACTCTT GTGCGTCAAA TTCTGACTCG GTTATCTGAT TGTTTTCTTT TCAATACAGA TTTGGGCGAT GTACAACATC CATCAACGGC CAAACTGGTA TGTACAGATT GTGAGTCGAT CCGGTGAGCG ATTCGATCTA AACGTAAACG AACGAGGAAA GAAAGGTTCT CGTCTTCCTC TTCGCATCGA GTGCAGATTT TTGGAGCTAA CTAAACCTTA CGAAGCTGGA CAGCTGGATT TGTGGAGTAC AATCAGAGGC TGTGGTCTGT ATACTGTGTC GGAAGGTATT GAAGTACAGG GGTCGTGGGT TGCATTTTCT CATCAAGTGA CTAGTCTCCT GAAAGTAGAT CATGGTCTAA TTTTCATCTA TCCTGCCAAG GGCGAAGTTT GGTCCGTCTA TGATAGTGGA ACTGAAAGCC GCTATCTTGT TTATGTGCTC GAGAGCTCTG TGAATACAAA AAAAGCGAAA TTGCGAGTTC CAGGGAAGGA AGGCTTCTCT GCTCGTTGTC GCCTGCTACA GAAAAAGATA GAGCTCGATC TTTACAGAAT TATAGACAAG GAACTAGTGT ATACCGATCT AGGAGTTTTC TCGTTCCGAG CTCCATATCA TTTCCATGGT GAGGGAGATG TTTTGAAGAT CGAGCTCTCG GTCAAAGATC GAGAGAGAGG AGCACAGATT GATGGTCTCA AGAGGAAAAG ATTATCTAGA CATTTTGAAT CAGATGATGA GGACTTCCTG GATATGGATA TAGGGGACGA ATTTGGAGCC ATGCCTATAG CGATTGGGAA TATTACAAGC GAGCCTCTTG CCAATGGGGA GTCTAAAAGC GAGTCAATTT TAACTGTAGT GACGAAGAGA GATGAGGAAC GGTTGGTGCA ACCCAAAGAA GACGCTATAA GAGGGCATTT GGAGCCTCTC AAGTTGAAGC CAGCACCCAG AAGATCCAGC CGAAGTACTG CGGGTCTGCG AAGTACGCCT TACACACCAT GAGACAAAGT ACTGGATTCG ATTGTACACT GCTGTTGCGC AATTTGTGGG AGTTGAAAAA CTTTACTTAT TTCTTGAAAC ACCATTATTA ATAAATAATG GTGTTAGTAA TGGACAACTA AGTAATATAC ATAGGCGTAT CATCTCGACG GTCGAGAAAT GAGGGGTTTC GAGGTTGTCA CTAAGGAGTC CAGTTCATTC TCGGGAAAAC TTCAGCGGGG GATATGGACG CGCATTACCG CACTTGATTA AGCTTTACCG TGAAGACCGA ATCTCCTACA GGTTTCACGG CAGTTCAAAA CTTCCGACCC CTTGAAATTT GTTTTGATTC AAGTTCTTCC ATGGAAGTAG ATGTCAGGGT CTACAGGCGA CAATGGATTA TGAATTACAA ATAACATTTT TCAAATTTAC TAGTTACAAA TTACAAATTT TATCAACCCA AGCGAGAGTC TCCAGGGTAA ACTGAATGCT TAATGATAAC ATAATCGGAA TTTTTTCCTT GTTTAGTTGC TCAGTGCC |
mRNA UTR + CDS |
| >Mp5g09290.1 GTCTGCGGGG AGAGATGGCC CGCTGGGTCC TCCGAATGAT TGTTGGGGAC TTTGTGTAGA GATGGGGTTC GTGACAGTGG AAACTGCAAA TTGCGTCCGC TCCTCTCGCA GCTTATGTCG ATCGGCGGGG TTGATTTCGC GCAGTCTGCA AGATGGGGTC GAAGCATCCT GCCATGGGTA CCACGATTTC CGACGATAGA ATCGATGGTC GAGAAGAGTC GATGTTCAAT TCGGTTAGAG GTAGTCTGAA AGGTGGCGCT AACCGGATGC AGCAAAGCCG ACCTGGACTC GGACAGCGTA GTCCAGATTG TGGGCTTCAG GAACCTTATT CCGGTGCGAA AGTTGTTGAC TAAGCTGCAT CATGCTCTAC TGAAGTTCGG TCATCGAGAA GCTCTTCCAT CCTCAACATG GACAAAGTCC TAAATCACAT AAGGAATCTC CGAGCCGAAG CTGAATCTTT GCTGAAAAAC GGGAACCGTC ATGATGGCGA TGACGAAGCT CACTGTGGCG TTGAGAAATC AATAGACTGC TCGAATTGCG GGGGTGACAG GTGGGTATTA AAACTTAGAC AAAAGGCCGG TTTCTGGAGG AGCAAACCTT TGGTGGTTCT CAGCTTATTC GATGGCATCG GTGGAGTGTG GGCGGCTCTC GAGAATCTTG GCATTCCTTT TATCGGGTAC AGCTGTGAGG TGAACGCCGA TGCGATGAAA GTGACCCAGC GAAATTACTG CTCTGTTCGT CATTTGGGAG ATATCCATCG ACTGAAAAAA GCAGACATAA AAGAGAAGAT AGACCTTGTT GTGGGTGGAT TTCCTTGTCA GGACTTGTCC TCCATGGGAG CGAGACTGGG GCTACACGGA AGTCGAAGCC GACTTTTCTT TGAAATGCTA CGAGTCATTA AAACATTCAG CCCAACATGG TTTCTTGCGG AAAATGTAGC CTCTATGAGT TGGGTGGATC GCGAAGAAAT CTCAAAGCAT CTGAGTACCA CTCCCTTGGA GATCGATTCT CAGAACTTCA GCCCTTGTAA ACGGAGGCGC CTGTACTGGT CAAACATACC CTATCCTAAG ACCTGTCCCC GCATCGGAGA TAATGAGGCA ACCTCTATCC AGAGCGTCGT TCAAGGGGGC GCTTCTCTGG CGAAGAAAAA CATGTGTGTA TTATCCTCAA ATGGTCTACA GGGTGCAACT AAAGCCCTGA TGGAACTAGT GTACGACTTT CGTATCGACA AGCCTCGCTA CATCAACGTG GTGGAAGTAG AACAAATGAT GGGATACCCC CCGCACTACA CCAACGTGAA GTTTGATGAT CAGAAACCGA AGGCAAAAAT TCAGAGGCGT CGAGAGACCG AAATTAAGGA GGGAGGGGTT GACCGAAACA CCAGATGGCG GCTATTGGGC AACTCGTTCT CAGTTCCGGT GATATCGTTT CTCTTGAGCC CCCTGTTAGA TGCTGACATC CGAGATCAGA CCAGGAAATA CCATCTTCCA GCGTCGGTTC GGGAGGCAGA CTGCTCCGTC ATGTCTCCAG GCGAGATTTG GGCGATGTAC AACATCCATC AACGGCCAAA CTGGTATGTA CAGATTGTGA GTCGATCCGG TGAGCGATTC GATCTAAACG TAAACGAACG AGGAAAGAAA GGTTCTCGTC TTCCTCTTCG CATCGAGTGC AGATTTTTGG AGCTAACTAA ACCTTACGAA GCTGGACAGC TGGATTTGTG GAGTACAATC AGAGGCTGTG GTCTGTATAC TGTGTCGGAA GGTATTGAAG TACAGGGGTC GTGGGTTGCA TTTTCTCATC AAGTGACTAG TCTCCTGAAA GTAGATCATG GTCTAATTTT CATCTATCCT GCCAAGGGCG AAGTTTGGTC CGTCTATGAT AGTGGAACTG AAAGCCGCTA TCTTGTTTAT GTGCTCGAGA GCTCTGTGAA TACAAAAAAA GCGAAATTGC GAGTTCCAGG GAAGGAAGGC TTCTCTGCTC GTTGTCGCCT GCTACAGAAA AAGATAGAGC TCGATCTTTA CAGAATTATA GACAAGGAAC TAGTGTATAC CGATCTAGGA GTTTTCTCGT TCCGAGCTCC ATATCATTTC CATGGTGAGG GAGATGTTTT GAAGATCGAG CTCTCGGTCA AAGATCGAGA GAGAGGAGCA CAGATTGATG GTCTCAAGAG GAAAAGATTA TCTAGACATT TTGAATCAGA TGATGAGGAC TTCCTGGATA TGGATATAGG GGACGAATTT GGAGCCATGC CTATAGCGAT TGGGAATATT ACAAGCGAGC CTCTTGCCAA TGGGGAGTCT AAAAGCGAGT CAATTTTAAC TGTAGTGACG AAGAGAGATG AGGAACGGTT GGTGCAACCC AAAGAAGACG CTATAAGAGG GCATTTGGAG CCTCTCAAGT TGAAGCCAGC ACCCAGAAGA TCCAGCCGAA GTACTGCGGG TCTGCGAAGT ACGCCTTACA CACCATGAGA CAAAGTACTG GATTCGATTG TACACTGCTG TTGCGCAATT TGTGGGAGTT GAAAAACTTT ACTTATTTCT TGAAACACCA TTATTAATAA ATAATGGTGT TAGTAATGGA CAACTAAGTA ATATACATAG GCGTATCATC TCGACGGTCG AGAAATGAGG GGTTTCGAGG TTGTCACTAA GGAGTCCAGT TCATTCTCGG GAAAACTTCA GCGGGGGATA TGGACGCGCA TTACCGCACT TGATTAAGCT TTACCGTGAA GACCGAATCT CCTACAGGTT TCACGGCAGT TCAAAACTTC CGACCCCTTG AAATTTGTTT TGATTCAAGT TCTTCCATGG AAGTAGATGT CAGGGTCTAC AGGCGACAAT GGATTATGAA TTACAAATAA CATTTTTCAA ATTTACTAGT TACAAATTAC AAATTTTATC AACCCAAGCG AGAGTCTCCA GGGTAAACTG AATGCTTAAT GATAACATAA TCGGAATTTT TTCCTTGTTT AGTTGCTCAG TGCC |
CDS |
| >Mp5g09290.1 ATGGACAAAG TCCTAAATCA CATAAGGAAT CTCCGAGCCG AAGCTGAATC TTTGCTGAAA AACGGGAACC GTCATGATGG CGATGACGAA GCTCACTGTG GCGTTGAGAA ATCAATAGAC TGCTCGAATT GCGGGGGTGA CAGGTGGGTA TTAAAACTTA GACAAAAGGC CGGTTTCTGG AGGAGCAAAC CTTTGGTGGT TCTCAGCTTA TTCGATGGCA TCGGTGGAGT GTGGGCGGCT CTCGAGAATC TTGGCATTCC TTTTATCGGG TACAGCTGTG AGGTGAACGC CGATGCGATG AAAGTGACCC AGCGAAATTA CTGCTCTGTT CGTCATTTGG GAGATATCCA TCGACTGAAA AAAGCAGACA TAAAAGAGAA GATAGACCTT GTTGTGGGTG GATTTCCTTG TCAGGACTTG TCCTCCATGG GAGCGAGACT GGGGCTACAC GGAAGTCGAA GCCGACTTTT CTTTGAAATG CTACGAGTCA TTAAAACATT CAGCCCAACA TGGTTTCTTG CGGAAAATGT AGCCTCTATG AGTTGGGTGG ATCGCGAAGA AATCTCAAAG CATCTGAGTA CCACTCCCTT GGAGATCGAT TCTCAGAACT TCAGCCCTTG TAAACGGAGG CGCCTGTACT GGTCAAACAT ACCCTATCCT AAGACCTGTC CCCGCATCGG AGATAATGAG GCAACCTCTA TCCAGAGCGT CGTTCAAGGG GGCGCTTCTC TGGCGAAGAA AAACATGTGT GTATTATCCT CAAATGGTCT ACAGGGTGCA ACTAAAGCCC TGATGGAACT AGTGTACGAC TTTCGTATCG ACAAGCCTCG CTACATCAAC GTGGTGGAAG TAGAACAAAT GATGGGATAC CCCCCGCACT ACACCAACGT GAAGTTTGAT GATCAGAAAC CGAAGGCAAA AATTCAGAGG CGTCGAGAGA CCGAAATTAA GGAGGGAGGG GTTGACCGAA ACACCAGATG GCGGCTATTG GGCAACTCGT TCTCAGTTCC GGTGATATCG TTTCTCTTGA GCCCCCTGTT AGATGCTGAC ATCCGAGATC AGACCAGGAA ATACCATCTT CCAGCGTCGG TTCGGGAGGC AGACTGCTCC GTCATGTCTC CAGGCGAGAT TTGGGCGATG TACAACATCC ATCAACGGCC AAACTGGTAT GTACAGATTG TGAGTCGATC CGGTGAGCGA TTCGATCTAA ACGTAAACGA ACGAGGAAAG AAAGGTTCTC GTCTTCCTCT TCGCATCGAG TGCAGATTTT TGGAGCTAAC TAAACCTTAC GAAGCTGGAC AGCTGGATTT GTGGAGTACA ATCAGAGGCT GTGGTCTGTA TACTGTGTCG GAAGGTATTG AAGTACAGGG GTCGTGGGTT GCATTTTCTC ATCAAGTGAC TAGTCTCCTG AAAGTAGATC ATGGTCTAAT TTTCATCTAT CCTGCCAAGG GCGAAGTTTG GTCCGTCTAT GATAGTGGAA CTGAAAGCCG CTATCTTGTT TATGTGCTCG AGAGCTCTGT GAATACAAAA AAAGCGAAAT TGCGAGTTCC AGGGAAGGAA GGCTTCTCTG CTCGTTGTCG CCTGCTACAG AAAAAGATAG AGCTCGATCT TTACAGAATT ATAGACAAGG AACTAGTGTA TACCGATCTA GGAGTTTTCT CGTTCCGAGC TCCATATCAT TTCCATGGTG AGGGAGATGT TTTGAAGATC GAGCTCTCGG TCAAAGATCG AGAGAGAGGA GCACAGATTG ATGGTCTCAA GAGGAAAAGA TTATCTAGAC ATTTTGAATC AGATGATGAG GACTTCCTGG ATATGGATAT AGGGGACGAA TTTGGAGCCA TGCCTATAGC GATTGGGAAT ATTACAAGCG AGCCTCTTGC CAATGGGGAG TCTAAAAGCG AGTCAATTTT AACTGTAGTG ACGAAGAGAG ATGAGGAACG GTTGGTGCAA CCCAAAGAAG ACGCTATAAG AGGGCATTTG GAGCCTCTCA AGTTGAAGCC AGCACCCAGA AGATCCAGCC GAAGTACTGC GGGTCTGCGA AGTACGCCTT ACACACCATG A |
Protein |
| >Mp5g09290.1 MDKVLNHIRN LRAEAESLLK NGNRHDGDDE AHCGVEKSID CSNCGGDRWV LKLRQKAGFW RSKPLVVLSL FDGIGGVWAA LENLGIPFIG YSCEVNADAM KVTQRNYCSV RHLGDIHRLK KADIKEKIDL VVGGFPCQDL SSMGARLGLH GSRSRLFFEM LRVIKTFSPT WFLAENVASM SWVDREEISK HLSTTPLEID SQNFSPCKRR RLYWSNIPYP KTCPRIGDNE ATSIQSVVQG GASLAKKNMC VLSSNGLQGA TKALMELVYD FRIDKPRYIN VVEVEQMMGY PPHYTNVKFD DQKPKAKIQR RRETEIKEGG VDRNTRWRLL GNSFSVPVIS FLLSPLLDAD IRDQTRKYHL PASVREADCS VMSPGEIWAM YNIHQRPNWY VQIVSRSGER FDLNVNERGK KGSRLPLRIE CRFLELTKPY EAGQLDLWST IRGCGLYTVS EGIEVQGSWV AFSHQVTSLL KVDHGLIFIY PAKGEVWSVY DSGTESRYLV YVLESSVNTK KAKLRVPGKE GFSARCRLLQ KKIELDLYRI IDKELVYTDL GVFSFRAPYH FHGEGDVLKI ELSVKDRERG AQIDGLKRKR LSRHFESDDE DFLDMDIGDE FGAMPIAIGN ITSEPLANGE SKSESILTVV TKRDEERLVQ PKEDAIRGHL EPLKLKPAPR RSSRSTAGLR STPYTP |