Mp6g04140
Description
Annotation
| Database | ID | Description |
|---|---|---|
| Gene3D | G3DSA:3.65.10.10 | Enolpyruvate transferase domain |
| Pfam | PF00275 | EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) |
| Hamap | MF_00210 | 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. |
| ProSitePatterns | PS00885 | EPSP synthase signature 2. |
| FunFam | G3DSA:3.65.10.10:FF:000009 | 3-phosphoshikimate 1-carboxyvinyltransferase |
| SUPERFAMILY | SSF55205 | EPT/RTPC-like |
| ProSitePatterns | PS00104 | EPSP synthase signature 1. |
| FunFam | G3DSA:3.65.10.10:FF:000004 | 3-phosphoshikimate 1-carboxyvinyltransferase |
| CDD | cd01556 | EPSP_synthase |
| PANTHER | PTHR21090 | AROM/DEHYDROQUINATE SYNTHASE |
| NCBIfam | TIGR01356 | 3-phosphoshikimate 1-carboxyvinyltransferase |
| KEGG | K00800 | 3-phosphoshikimate 1-carboxyvinyltransferase [EC:2.5.1.19] |
| KOG | KOG0692 | Pentafunctional AROM protein; [E] |
| MapolyID | Mapoly0034s0104 | - |
| GO | GO:0003824 | catalytic activity |
| GO | GO:0009073 | aromatic amino acid family biosynthetic process |
| GO | GO:0009423 | chorismate biosynthetic process |
| GO | GO:0003866 | 3-phosphoshikimate 1-carboxyvinyltransferase activity |
| GO | GO:0016765 | transferase activity, transferring alkyl or aryl (other than methyl) groups |
Nomenclature
| Gene symbol | Product | Transcript ID | Status |
|---|---|---|---|
| MpEPSPS | Secondary metabolism enzyme | Provisional |
Associated Literature (AI-based literature mining, Beta-version)
Secondary metabolism enzyme (from nomenclature)
0 core 1 peripheral
Caygill, S., et al. (2024)
· Proceeding of the National Academy of Sciences USA research experimental comparator
Recombinant M. polymorpha EPSPS was kinetically characterized; its glyphosate IC50 (9.60 uM) is not significantly different from A. thaliana EPSPS (14.49 uM), with near-identical predicted structure, showing tolerance is not attributable to a glyphosate-insensitive EPSPS.
Single-cell expression scRNA-seq atlas from Wang et al., 2023
Expression of Mp6g04140 across the single-cell RNA-seq atlas. Cluster identities (right) annotate the same UMAP used for the feature plot (left).
Gene structure:
Sequences: |
Gene UTR + CDS + intron |
| >Mp6g04140.1 GCGGGAGTCA AATAAGTGTC CGGTTGCTGC GAGTCAGGAT GATGGAATAA TTATTGCTCT GACGATGTGG ATTCAGTGTT CTTGAGCCCT GCCTGGTGAG GGTAGCACTA GCTTGCAGTG CGAAGGGTTT GCAGCAGTAC GCCCCAAGCT CCTCCCGGTG CATCTTCTCG TTGTTTGGTG AAGGAACGAG AAGAGAGGAG CAGAGGTGTC GCACTGCATT GTTGGTTGAA GCGATGGAGT CTCTGAGGGC CGCTGCGGTC TCGACCCAAC TGAAATTCCC CTCTGCTTGC GATGTACAGA GCTCTCGAAG TGCCAGGTCT GCTCGAAATG TCGTCGTGCG CTTTGATCGC GCTCTTGGAT CTCTGTCCTT GAACAGGAAG GCGGGACTTC ATGCCAAAAG CTGTGCAGAT CTTCCAAAGA CTAAGACCTT CAAGCTCAAG AATTTGAGCC AGGGGTGCAG AGCTTCCGCG ACTGCCGCAC CAGCTGCTCC TGTTGAGGAG ATTGAGTTGC CTCCAGTGAA GAATATCTCG GGGACCATCA AGCTTCCGGG ATCTAAGTCG CTTTCCAACC GTGTGCTTCT CCTCGCTGCC CTTGCTGAGG TTAGTTTCAT AAGATTTGCT ACACGGAACA AGCGCTGTGC GCTCTGAGGC TTGGCGATCA TGATACTTGT CTGGCAGTTG AATTTTGTAC TGTTTTCCCT CTATTTTTCT AAAAGCACCA ATTTATTTAT GTTTGCAATT TTTCTTATGG TCTTGTCGTG GAGAAGTTAA CCAATCCCTA GAGCAAGCCT TTATGTCGTG AACACAATTG TCTGCATGTG TTTGTTTTAC TTAAACCGAC TACAGACACT TCTATTTTAT TTGGATATAA AATGATCAAT TCAGGCCAGG TGCTGGATGG ACTCGGTGAC AGTGTCGACC AATTTCCTCC GATATTTAGA CCTCTGTACC GAGAATCTAT TCTGGAAGAA TTGTCTCGAG GAGTTTTTTC AAGCCTTGAG AGTTGGATTA TGTTATGTTC AATGCTTGAA GATCATCCTT AATCATTAGA GATTTATAAT AGAGGTATCT CACAGGCTTG TCCTGGACCT GCATTGCTGA ATATAGTTGC CCATGAACTG TAGTGTACAG TCATTTATAT ATCTGCCGGA ATTTTTCTAG TTTTTTTTTC ACTACTTGTT TGCCTCTGTT GAACTCATGA AGTGGTGACG ACTGGTCAAT TTTGTTTGTG CGATGAACTC ATGATTAGCT TGTAACTCTT GTTTGGAGTC TGTAAGTTAG AAAATAGCAA GAAGAAAATT GGGTTCTCGC ATGAAGCTCG CATCCTTTGG TGTTTGACAG GGCACAACAG TTGTCGATAA CCTTCTCGAC AGTGATGATG TTCGATACAT GGTTGGCGCG CTCAATCAGC TGGGACTTAA GTTAACAGAG AACTGGGAGA CTAAGCAGAT CATCGTTGAA GGTTGTGGTG GCCTCTTCCC TGTGGGAAAA GAAGAACAGT TGGTTGAGTT GTTTTTGGGG AATGCTGGTA CTGCCATGAG ACCATTGACA GCGGCAGTAG CTGTAGCAGG TGGAAAAGCC AAGTAAGCAA TCGGCCCTGT TATGTTATCG GCCCTCTTAT GTCGTCTGTG GATTTTTAGT ATCTCTTACA AAACCTCGAG GGAGATACAA GGAAGTAGAT CCGTGTTAGA TAACTTCGGT TTTCTTTTGT CATCTCGATT CTGGCTTTAC CTTTCTTTAA CTTTTCATAT GTACGTAGTT CAAGATTTCG ACCAATTCTA AAAAATTTGT TTTGGCTGCT TGGAGATATC AGCTGGAGGT TTCTATGTGT TCACAGAAGA AACATTATTT TTTTGTTTGA TGTTTTGATC ACCATTACCT CGAAACTGAG CTGGTGTCCT TTATGTGCAC TTTTAAATCC GGGTGGTTTC TAGGGCACTT TTGTATGCTT TATAGCTTCA ATGACCTTCA CATTTCATCA AGTCGCACCT GCACGCAGTG AAGCTCACAG TTGCTCAGGA AGAATCACAG GTCAGAAGAC CTGCAAACTC TTGTCTGTTG TTGTCAGTGT TTCTGACAAT GTCATACAAC AGATATATCC TGGATGGAGT ACCACGTATG AGAGAAAGAC CTATTGGGGA TCTTGTTGAG GGTATGAAGC AGCTTGGAGC AGACGTCAGC TGCAGCGAGA CTCAGTGTCC ACCTGTGCAT GTGAACGCAG CTGGTGGACT TCCCGGAGGA ACGGTAAGTG GAAGAATTTT ATCTGCCGGC ATGCAATCTG TTGATTGTAA CAAGCGTATT AGTTTGCATC GATGTTGCCC TGATATGAGA TTGTCGTTCC AGGTAAGGCT CTCTGGAGCT GTAAGCAGCC AATATTTGAC GGCATTACTT ATGGCGGCAC CATTAGCTCG TGAAGACATC GAGATTGTGA TGGTCGACGA GCTGGTGTCA AAGCCGTATG TGGACATGAC TCTGAAACTC ATGGAGCGTT TTGGAGTTAA GGTGGAGCGC TATGGAGACT GGAAAAGATT CTCTATCAAG GGTGGGCAGA CCTTCAAGTA TGTATCCAGT TTGATTCTCA ATCCAACTAT TTTCTTATTT CATTGAAACA TTATTTTCCT TAGTTCACCC CGGAGATGAA CTCTTTGAGG TGCTGGTCAT CACATGGAAA GGCATGGTTA GGCATCTGCA GAAGCAGTAA CAAGAAGACG GTTTCGATGC ACTTGATGGT TGATCGACGA GACCTTGATG TAACTGTGTC TAGGTCACCA GGAACAGCCT ACGTTGAAGG GGATGCTTCC AGCGCTAGTT ACTTCCTTGC GGGTGCTGCC ATCACCGGAG GAAAAGTAAC AGTCGAAGGG TGTGGATCTA GCAGCTTACA GGTCTGTAAT ACATGAACCT CTTCCAGGTT ATATACTGCT TCGTCATGAT GGTGGTGTGT TGTGGATCTG GATTCAGAGT ATCCTAATTC TTGTTCATAA TCCAACTGAG ATGGATACAA TGTGCGTAGG GAGATGTGAA CTTTGCCGAA GTCCTCGGAC AAATGGGATG CAAGGTGGAT TGGACCGAGT ATAGCGTGAG TGTAACCGGC CCACCTGTAA ACAAAGCCAC AGGAAAGCGG CTGAAGGCCA TCGACGTGAA CATGAACGCC ATGCCCGATG TAGCAATGAC ACTTGCTGTG GTTGCTCTGT TTGCTGATGG CACGACTGCT ATCAGAGATG GTGAGTAGCA AGATTACCTT CACGTGAATA TTATATTATT CACGTGAATT AAGTTGGGCT GATTTGTGTT TTTTCTGAGT GTTCTGCTTG ATCTTCCCTC CCATCTAATT TCTTCTTGTC CCCAAGCTGT TCCTACTAGC ACCTTTGAGC TACGGTGCGG GGTCTATGGT CTCCAGGCTG TGACAGACTG ATACTGATGA GCAGAGTTCT GGAAAACTTG CAGTTGGCAA CTGGAGAGTA AAAGAGACAG AAAGGATGGT GGCTATCGTG ACAGAACTCG GAAAGGTGAG ATTATATTCA AATGCTTCTT CTTGAAATAT GCTGATATCA GAATTGTTTC TCCTCTTTAT CATGGGCCCG CATTCCCAGG ACCAGCAGAT CTCCTCTGCA GTCACTCGTG CTTCTGCAGT ATAGCCTACC TCCATGTACT GGAGAGGATA CTAAACAGGA ACATACTACA GCAGATCAAT CTGTGTTTTT TAGACGGTCC CAGGTGTCAT CAACTCGTAC TAATCATTGG CTAACATTGG TACTAAAAAC TTGCTGATCA TCCCTCATGT AGATTGGAGC CATTGTTGAA GAAGGACAAG ATTACTGCAT CATTACACCT CCAGAGAAAC TTCAAGACGC AGCCATTGAC ACTTACGATG ATCACCGCAT GGCCATGGCC TTCTCTCTTG CTGCTTGTGG TGACTCGAAA ATTATCATCA GAGATCCTGG CTGCACAAGA AAGACCTTCC CAGATTACTT CGAGAAGTTC GCACAATTTT CGTCTGCCTA GAAGTTACAA ATTAGAGCAC GCCTATTAAA ATTTTTAGGT CTAGAAGTTC GCCCATTATT TCTTCAATAA GCTTGAGTTC GTTAGTTTCA ACAGCCAGCT GTGATTGGTT GGCTCGGACT CTGAAGCCGA AAATTCCACC AAAGATCTTA GAGAAGGTCA AAGAGAAGAT CAAGTATTCA TCTATAGGTT TTGATCGCCG CGGTTAAGTT CTGGGGACCC CTGAGATTGG ATATAGTCAT TGCAGCCAAG CGACTTCTGT ACAGAAGTAG TGTAGGAAGT TGAAGAAGAC TTCGGAGTCA GAATCTTCCA AGACTCCATG GGAAGTGTTT AACTAACTAC GTCGAGAATG TCCACATCAA TGCAAGAATT GACTGCCTCC |
mRNA UTR + CDS |
| >Mp6g04140.1 GCGGGAGTCA AATAAGTGTC CGGTTGCTGC GAGTCAGGAT GATGGAATAA TTATTGCTCT GACGATGTGG ATTCAGTGTT CTTGAGCCCT GCCTGGTGAG GGTAGCACTA GCTTGCAGTG CGAAGGGTTT GCAGCAGTAC GCCCCAAGCT CCTCCCGGTG CATCTTCTCG TTGTTTGGTG AAGGAACGAG AAGAGAGGAG CAGAGGTGTC GCACTGCATT GTTGGTTGAA GCGATGGAGT CTCTGAGGGC CGCTGCGGTC TCGACCCAAC TGAAATTCCC CTCTGCTTGC GATGTACAGA GCTCTCGAAG TGCCAGGTCT GCTCGAAATG TCGTCGTGCG CTTTGATCGC GCTCTTGGAT CTCTGTCCTT GAACAGGAAG GCGGGACTTC ATGCCAAAAG CTGTGCAGAT CTTCCAAAGA CTAAGACCTT CAAGCTCAAG AATTTGAGCC AGGGGTGCAG AGCTTCCGCG ACTGCCGCAC CAGCTGCTCC TGTTGAGGAG ATTGAGTTGC CTCCAGTGAA GAATATCTCG GGGACCATCA AGCTTCCGGG ATCTAAGTCG CTTTCCAACC GTGTGCTTCT CCTCGCTGCC CTTGCTGAGG GCACAACAGT TGTCGATAAC CTTCTCGACA GTGATGATGT TCGATACATG GTTGGCGCGC TCAATCAGCT GGGACTTAAG TTAACAGAGA ACTGGGAGAC TAAGCAGATC ATCGTTGAAG GTTGTGGTGG CCTCTTCCCT GTGGGAAAAG AAGAACAGTT GGTTGAGTTG TTTTTGGGGA ATGCTGGTAC TGCCATGAGA CCATTGACAG CGGCAGTAGC TGTAGCAGGT GGAAAAGCCA AATATATCCT GGATGGAGTA CCACGTATGA GAGAAAGACC TATTGGGGAT CTTGTTGAGG GTATGAAGCA GCTTGGAGCA GACGTCAGCT GCAGCGAGAC TCAGTGTCCA CCTGTGCATG TGAACGCAGC TGGTGGACTT CCCGGAGGAA CGGTAAGGCT CTCTGGAGCT GTAAGCAGCC AATATTTGAC GGCATTACTT ATGGCGGCAC CATTAGCTCG TGAAGACATC GAGATTGTGA TGGTCGACGA GCTGGTGTCA AAGCCGTATG TGGACATGAC TCTGAAACTC ATGGAGCGTT TTGGAGTTAA GGTGGAGCGC TATGGAGACT GGAAAAGATT CTCTATCAAG GGTGGGCAGA CCTTCAAGTC ACCAGGAACA GCCTACGTTG AAGGGGATGC TTCCAGCGCT AGTTACTTCC TTGCGGGTGC TGCCATCACC GGAGGAAAAG TAACAGTCGA AGGGTGTGGA TCTAGCAGCT TACAGGGAGA TGTGAACTTT GCCGAAGTCC TCGGACAAAT GGGATGCAAG GTGGATTGGA CCGAGTATAG CGTGAGTGTA ACCGGCCCAC CTGTAAACAA AGCCACAGGA AAGCGGCTGA AGGCCATCGA CGTGAACATG AACGCCATGC CCGATGTAGC AATGACACTT GCTGTGGTTG CTCTGTTTGC TGATGGCACG ACTGCTATCA GAGATGTTGG CAACTGGAGA GTAAAAGAGA CAGAAAGGAT GGTGGCTATC GTGACAGAAC TCGGAAAGAT TGGAGCCATT GTTGAAGAAG GACAAGATTA CTGCATCATT ACACCTCCAG AGAAACTTCA AGACGCAGCC ATTGACACTT ACGATGATCA CCGCATGGCC ATGGCCTTCT CTCTTGCTGC TTGTGGTGAC TCGAAAATTA TCATCAGAGA TCCTGGCTGC ACAAGAAAGA CCTTCCCAGA TTACTTCGAG AAGTTCGCAC AATTTTCGTC TGCCTAGAAG TTACAAATTA GAGCACGCCT ATTAAAATTT TTAGGTCTAG AAGTTCGCCC ATTATTTCTT CAATAAGCTT GAGTTCGTTA GTTTCAACAG CCAGCTGTGA TTGGTTGGCT CGGACTCTGA AGCCGAAAAT TCCACCAAAG ATCTTAGAGA AGGTCAAAGA GAAGATCAAG TATTCATCTA TAGGTTTTGA TCGCCGCGGT TAAGTTCTGG GGACCCCTGA GATTGGATAT AGTCATTGCA GCCAAGCGAC TTCTGTACAG AAGTAGTGTA GGAAGTTGAA GAAGACTTCG GAGTCAGAAT CTTCCAAGAC TCCATGGGAA GTGTTTAACT AACTACGTCG AGAATGTCCA CATCAATGCA AGAATTGACT GCCTCC |
CDS |
| >Mp6g04140.1 ATGGAGTCTC TGAGGGCCGC TGCGGTCTCG ACCCAACTGA AATTCCCCTC TGCTTGCGAT GTACAGAGCT CTCGAAGTGC CAGGTCTGCT CGAAATGTCG TCGTGCGCTT TGATCGCGCT CTTGGATCTC TGTCCTTGAA CAGGAAGGCG GGACTTCATG CCAAAAGCTG TGCAGATCTT CCAAAGACTA AGACCTTCAA GCTCAAGAAT TTGAGCCAGG GGTGCAGAGC TTCCGCGACT GCCGCACCAG CTGCTCCTGT TGAGGAGATT GAGTTGCCTC CAGTGAAGAA TATCTCGGGG ACCATCAAGC TTCCGGGATC TAAGTCGCTT TCCAACCGTG TGCTTCTCCT CGCTGCCCTT GCTGAGGGCA CAACAGTTGT CGATAACCTT CTCGACAGTG ATGATGTTCG ATACATGGTT GGCGCGCTCA ATCAGCTGGG ACTTAAGTTA ACAGAGAACT GGGAGACTAA GCAGATCATC GTTGAAGGTT GTGGTGGCCT CTTCCCTGTG GGAAAAGAAG AACAGTTGGT TGAGTTGTTT TTGGGGAATG CTGGTACTGC CATGAGACCA TTGACAGCGG CAGTAGCTGT AGCAGGTGGA AAAGCCAAAT ATATCCTGGA TGGAGTACCA CGTATGAGAG AAAGACCTAT TGGGGATCTT GTTGAGGGTA TGAAGCAGCT TGGAGCAGAC GTCAGCTGCA GCGAGACTCA GTGTCCACCT GTGCATGTGA ACGCAGCTGG TGGACTTCCC GGAGGAACGG TAAGGCTCTC TGGAGCTGTA AGCAGCCAAT ATTTGACGGC ATTACTTATG GCGGCACCAT TAGCTCGTGA AGACATCGAG ATTGTGATGG TCGACGAGCT GGTGTCAAAG CCGTATGTGG ACATGACTCT GAAACTCATG GAGCGTTTTG GAGTTAAGGT GGAGCGCTAT GGAGACTGGA AAAGATTCTC TATCAAGGGT GGGCAGACCT TCAAGTCACC AGGAACAGCC TACGTTGAAG GGGATGCTTC CAGCGCTAGT TACTTCCTTG CGGGTGCTGC CATCACCGGA GGAAAAGTAA CAGTCGAAGG GTGTGGATCT AGCAGCTTAC AGGGAGATGT GAACTTTGCC GAAGTCCTCG GACAAATGGG ATGCAAGGTG GATTGGACCG AGTATAGCGT GAGTGTAACC GGCCCACCTG TAAACAAAGC CACAGGAAAG CGGCTGAAGG CCATCGACGT GAACATGAAC GCCATGCCCG ATGTAGCAAT GACACTTGCT GTGGTTGCTC TGTTTGCTGA TGGCACGACT GCTATCAGAG ATGTTGGCAA CTGGAGAGTA AAAGAGACAG AAAGGATGGT GGCTATCGTG ACAGAACTCG GAAAGATTGG AGCCATTGTT GAAGAAGGAC AAGATTACTG CATCATTACA CCTCCAGAGA AACTTCAAGA CGCAGCCATT GACACTTACG ATGATCACCG CATGGCCATG GCCTTCTCTC TTGCTGCTTG TGGTGACTCG AAAATTATCA TCAGAGATCC TGGCTGCACA AGAAAGACCT TCCCAGATTA CTTCGAGAAG TTCGCACAAT TTTCGTCTGC CTAG |
Protein |
| >Mp6g04140.1 MESLRAAAVS TQLKFPSACD VQSSRSARSA RNVVVRFDRA LGSLSLNRKA GLHAKSCADL PKTKTFKLKN LSQGCRASAT AAPAAPVEEI ELPPVKNISG TIKLPGSKSL SNRVLLLAAL AEGTTVVDNL LDSDDVRYMV GALNQLGLKL TENWETKQII VEGCGGLFPV GKEEQLVELF LGNAGTAMRP LTAAVAVAGG KAKYILDGVP RMRERPIGDL VEGMKQLGAD VSCSETQCPP VHVNAAGGLP GGTVRLSGAV SSQYLTALLM AAPLAREDIE IVMVDELVSK PYVDMTLKLM ERFGVKVERY GDWKRFSIKG GQTFKSPGTA YVEGDASSAS YFLAGAAITG GKVTVEGCGS SSLQGDVNFA EVLGQMGCKV DWTEYSVSVT GPPVNKATGK RLKAIDVNMN AMPDVAMTLA VVALFADGTT AIRDVGNWRV KETERMVAIV TELGKIGAIV EEGQDYCIIT PPEKLQDAAI DTYDDHRMAM AFSLAACGDS KIIIRDPGCT RKTFPDYFEK FAQFSSA |