Mp6g18570



Description

Annotation

Database ID Description
MobiDBLite mobidb-lite consensus disorder prediction
Pfam PF12624 VPS13-like, N-terminal
Pfam PF13329 Autophagy-related protein 2, middle RBG modules
PANTHER PTHR13190 AUTOPHAGY-RELATED 2, ISOFORM A
Coils Coil Coil
Pfam PF09333 ATG2/VPS13, C terminal domain
KEGG K17906 autophagy-related protein 2
KOG KOG2993 Cytoplasm to vacuole targeting protein; N-term missing; [U]
KOG KOG1809 Vacuolar protein sorting-associated protein; C-term missing; [U]
MapolyID Mapoly0038s0067 -
GO GO:0032266 phosphatidylinositol-3-phosphate binding
GO GO:0000045 autophagosome assembly
GO GO:0061709 reticulophagy
GO GO:0044805 obsolete late nucleophagy
GO GO:0006914 autophagy
GO GO:0034727 piecemeal microautophagy of the nucleus
GO GO:0000422 autophagy of mitochondrion
GO GO:0000407 phagophore assembly site

Nomenclature

Gene symbol Product Transcript ID Status
MpATG2 Autophagy protein Provisional

Associated Literature (AI-based literature mining, Beta-version)

A core autophagy gene knocked out by CRISPR/Cas9 (Mpatg2-1ge frameshift). The mutant blocks vacuolar transport of fluorescent MpATG8, showing MpATG2 is required for autophagosome-mediated delivery and autophagy-dependent chlorophyll maintenance under nutrient stress.

1 core 1 peripheral

Norizuki, T., et al. (2019) · Frontiers in Plant Science  research experimental subject
A core autophagy gene knocked out by CRISPR/Cas9 (Mpatg2-1ge frameshift). The mutant blocks vacuolar transport of fluorescent MpATG8, showing MpATG2 is required for autophagosome-mediated delivery and autophagy-dependent chlorophyll maintenance under nutrient stress.
Goto-Yamada, S., et al. (2022) · Frontiers in Cell and Developmental Biology  review citation background
M. polymorpha ATG2 (peroxin/peroxisome biogenesis)

Transcript models

Transcript ID Location Sequences Extract region
Mp6g18570.1 chr6:24750931..24765082 (-) Gene /  mRNA /  CDS /  Protein
FASTA / GenBank (with flanking bases)
Mp6g18570.2 chr6:24750931..24765082 (-) Gene /  mRNA /  CDS /  Protein
FASTA / GenBank (with flanking bases)
Mp6g18570.3 chr6:24751035..24765082 (-) Gene /  mRNA /  CDS /  Protein
FASTA / GenBank (with flanking bases)
Mp6g18570.4 chr6:24751035..24765082 (-) Gene /  mRNA /  CDS /  Protein
FASTA / GenBank (with flanking bases)

Expression Level powered by MBEX

Link to the original image in MBEX

Single-cell expression scRNA-seq atlas from Wang et al., 2023

Expression of Mp6g18570 across the single-cell RNA-seq atlas. Cluster identities (right) annotate the same UMAP used for the feature plot (left).

Feature plot of Mp6g18570 on UMAP
Feature plot (Seurat scale expression level).
UMAP cluster annotation
Cell-type annotation of the UMAP clusters.
Violin plot by developmental stage
Violin plot by stage. Expression across developmental time points (D0–D31).
Violin plot by cell cluster
Violin plot by cluster. Expression across cell clusters (1–21).

Gene structure:

Sequences:

Gene UTR + CDS + intron

FASTA

mRNA UTR + CDS

FASTA

CDS

FASTA

Protein

FASTA

Gene structure:

Sequences:

Gene UTR + CDS + intron

FASTA

mRNA UTR + CDS

FASTA

CDS

FASTA

Protein

FASTA

Gene structure:

Sequences:

Gene UTR + CDS + intron

FASTA

mRNA UTR + CDS

FASTA

CDS

FASTA

Protein

FASTA

Gene structure:

Sequences:

Gene UTR + CDS + intron

FASTA

mRNA UTR + CDS

FASTA

CDS

FASTA

Protein

FASTA


MarpolBase / Genome Informatics Lab. NIG.