Mp7g17540



Description

Annotation

Database ID Description
CDD cd04133 Rop_like
SMART SM00174 rho_sub_3
NCBIfam TIGR00231 small GTP-binding protein domain
Pfam PF00071 Ras family
ProSiteProfiles PS51420 small GTPase Rho family profile.
PRINTS PR00449 Transforming protein P21 ras signature
PANTHER PTHR24072 RHO FAMILY GTPASE
Gene3D G3DSA:3.40.50.300 -
SUPERFAMILY SSF52540 P-loop containing nucleoside triphosphate hydrolases
FunFam G3DSA:3.40.50.300:FF:000535 rac-like GTP-binding protein RAC2
ProSiteProfiles PS51421 small GTPase Ras family profile.
SMART SM00173 ras_sub_4
SMART SM00175 rab_sub_5
ProSiteProfiles PS51419 small GTPase Rab1 family profile.
KEGG K04392 Ras-related C3 botulinum toxin substrate 1
KOG KOG0393 Ras-related small GTPase, Rho type; [R]
MapolyID Mapoly0051s0092 -
GO GO:0003924 GTPase activity
GO GO:0008360 regulation of cell shape
GO GO:0042995 cell projection
GO GO:0005856 cytoskeleton
GO GO:0030865 cortical cytoskeleton organization
GO GO:0005525 GTP binding
GO GO:0007264 small GTPase-mediated signal transduction
GO GO:0019901 protein kinase binding
GO GO:0031410 cytoplasmic vesicle
GO GO:0007163 establishment or maintenance of cell polarity
GO GO:0032956 regulation of actin cytoskeleton organization

Nomenclature

Gene symbol Product Transcript ID Status
MpROP ROP GTPase Published

Associated Literature (AI-based literature mining, Beta-version)

Sole ROP GTPase in Marchantia; CRISPR knockouts (Mprop-1/-2) show retarded rhizoid elongation and disorganized cell division. Regulates spatial cell-division patterns and meristem notch specification, localizing polarly to the plasma membrane. AtROP2 and complementation rescue wild-type phenotypes.

3 core 1 peripheral

Alisha A, Jarmolowski A, Szweykowska-Kulinska Z, Sierocka I. (2026) · The Plant journal : for cell and molecular biology  research experimental subject
MpROP (RHO OF PLANTS) mRNA was downregulated in Mpspl3 knockout mutants by qPCR here, linking MpSPL3 to rhizoid/meristem-related programs.
Mulvey, H., et al. (2023) · Current Biology  research experimental subject
RHO GTPase of plants (ROP; Mp7g17540); required for tissue development and organogenesis. Controls anisotropic diffuse growth orientation during gemma morphogenesis; CRISPR mutants and Venus-MpROP OE analyzed.
Rong, D., et al. (2022) · PNAS  research experimental subject
Sole ROP GTPase in Marchantia; CRISPR knockouts (Mprop-1/-2) show retarded rhizoid elongation and disorganized cell division. Regulates spatial cell-division patterns and meristem notch specification, localizing polarly to the plasma membrane. AtROP2 and complementation rescue wild-type phenotypes.
Hiwatashi, T., et al. (2019) · Current Biology   experimental tool
The only ROP GTPase in M. polymorpha; used as substrate in in vitro GEF assays showing KAR/PRONE domain has activity toward it.

Transcript models

Transcript ID Location Sequences Extract region
Mp7g17540.1 chr7:21836307..21840434 (+) Gene /  mRNA /  CDS /  Protein
FASTA / GenBank (with flanking bases)

Expression Level powered by MBEX

Link to the original image in MBEX

Single-cell expression scRNA-seq atlas from Wang et al., 2023

Expression of Mp7g17540 across the single-cell RNA-seq atlas. Cluster identities (right) annotate the same UMAP used for the feature plot (left).

Feature plot of Mp7g17540 on UMAP
Feature plot (Seurat scale expression level).
UMAP cluster annotation
Cell-type annotation of the UMAP clusters.
Violin plot by developmental stage
Violin plot by stage. Expression across developmental time points (D0–D31).
Violin plot by cell cluster
Violin plot by cluster. Expression across cell clusters (1–21).

Gene structure:

Sequences:

Gene UTR + CDS + intron

FASTA

mRNA UTR + CDS

FASTA

CDS

FASTA

Protein

FASTA

MarpolBase / Genome Informatics Lab. NIG.