Mp8g06840



Description

Annotation

Database ID Description
MobiDBLite mobidb-lite consensus disorder prediction
ProSiteProfiles PS50975 ATP-grasp fold profile.
FunFam G3DSA:3.40.50.11950:FF:000002 Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase
Pfam PF18086 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain
Gene3D G3DSA:3.40.50.1240 -
Gene3D G3DSA:3.30.470.20 -
CDD cd07061 HP_HAP_like
ProSitePatterns PS00616 Histidine acid phosphatases phosphohistidine signature.
Pfam PF00328 Histidine phosphatase superfamily (branch 2)
SUPERFAMILY SSF53254 Phosphoglycerate mutase-like
PANTHER PTHR12750 DIPHOSPHOINOSITOL PENTAKISPHOSPHATE KINASE
FunFam G3DSA:3.30.470.20:FF:000019 Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase
Gene3D G3DSA:3.40.50.11950 -
SUPERFAMILY SSF56059 Glutathione synthetase ATP-binding domain-like
KEGG K13024 inositol-hexakisphosphate/diphosphoinositol-pentakisphosphate 1-kinase [EC:2.7.4.24]
KOG KOG1057 Arp2/3 complex-interacting protein VIP1/Asp1, involved in regulation of actin cytoskeleton; [Z]
MapolyID Mapoly0013s0108 -
GO GO:0033857 5-diphosphoinositol pentakisphosphate 1-kinase activity
GO GO:0000829 diphosphoinositol pentakisphosphate kinase activity
GO GO:0046872 metal ion binding
GO GO:0006020 inositol metabolic process
GO GO:0005524 ATP binding
GO GO:0032958 inositol phosphate biosynthetic process
GO GO:0000828 inositol hexakisphosphate kinase activity

Nomenclature

Gene symbol Product Transcript ID Status
MpVIH inositol phosphate kinase Published

Associated Literature (AI-based literature mining, Beta-version)

Single PPIP5K gene encoding a bifunctional kinase/phosphatase. Mutants resemble Mppfa-dsp1 with vertical growth, reduced thallus, more rhizoids, fewer gemma cups, lower 1,5-InsP8 and higher 5-InsP7; the Mppfa-dsp1 Mpvip1 double mutant is severely stunted with high nitrate.

2 core 2 peripheral

Laurent, F., et al. (2025) · PLoS Genetics  research experimental subject
Single PPIP5K gene encoding a bifunctional kinase/phosphatase. Mutants resemble Mppfa-dsp1 with vertical growth, reduced thallus, more rhizoids, fewer gemma cups, lower 1,5-InsP8 and higher 5-InsP7; the Mppfa-dsp1 Mpvip1 double mutant is severely stunted with high nitrate.
Rana P, Edathil Kadangodan A, Koley P, Ghosh R, Pullagurla NJ, Naik HC, Mondal P, Gayen S, Laha D. (2025) · Nature chemical biology  research experimental subject
Diphosphoinositol-pentakisphosphate kinase responsible for synthesizing the inositol pyrophosphate messenger InsP8; MpVIH-derived InsP8 controls MpDELLA stability (validated by MpVIH-KD constructs, BiFC and docking).
Ghosh R, Yadav R, Pullagurla NJ, Rana P, Laha D. (2025) · FEBS letters  review citation background
Reviewed: MpVIH-derived inositol pyrophosphate InsP8 binds the growth repressor DELLA in M. polymorpha.
Pullagurla, N. J., et al. (2025) · Plant Physiology  research experimental comparator
VIH diphosphoinositol pentakisphosphate kinase; InsP pathway.

Transcript models

Transcript ID Location Sequences Extract region
Mp8g06840.1 chr8:9245828..9262055 (+) Gene /  mRNA /  CDS /  Protein
FASTA / GenBank (with flanking bases)

Expression Level powered by MBEX

Link to the original image in MBEX

Single-cell expression scRNA-seq atlas from Wang et al., 2023

Expression of Mp8g06840 across the single-cell RNA-seq atlas. Cluster identities (right) annotate the same UMAP used for the feature plot (left).

Feature plot of Mp8g06840 on UMAP
Feature plot (Seurat scale expression level).
UMAP cluster annotation
Cell-type annotation of the UMAP clusters.
Violin plot by developmental stage
Violin plot by stage. Expression across developmental time points (D0–D31).
Violin plot by cell cluster
Violin plot by cluster. Expression across cell clusters (1–21).

Gene structure:

Sequences:

Gene UTR + CDS + intron

FASTA

mRNA UTR + CDS

FASTA

CDS

FASTA

Protein

FASTA

MarpolBase / Genome Informatics Lab. NIG.