Mp2g04160



Description

Annotation

Database ID Description
Coils Coil Coil
Gene3D G3DSA:4.10.280.10 -
KOG KOG1319 bHLHZip transcription factor BIGMAX; N-term missing; C-term missing; [K]
MobiDBLite mobidb-lite consensus disorder prediction
PANTHER PTHR46684 TRANSCRIPTION FACTOR FAMA
Pfam PF00010 Helix-loop-helix DNA-binding domain
ProSiteProfiles PS50888 Myc-type, basic helix-loop-helix (bHLH) domain profile.
SMART SM00353 finulus
SUPERFAMILY SSF47459 HLH, helix-loop-helix DNA-binding domain
GO GO:0010052 guard cell differentiation
GO GO:0003700 DNA-binding transcription factor activity
GO GO:0046983 protein dimerization activity
MapolyID Mapoly0031s0072 -

Nomenclature

Gene symbol Product Transcript ID Status
MpBHLH35 transcription factor, bHLH Published
MpSETA transcription factor, bHLH Published

Associated Literature (AI-based literature mining)

A bHLH transcription factor (also called MpSMF). Constitutive/steroid-inducible ectopic MpSETA expression in thalli caused air pore/air chamber defects, ectopic pegged rhizoids, and thallus dwarfism, while Mpseta knockouts showed no obvious thallus defect and MpSETA was not detected in wild-type thallus, indicating its native role is mainly in diploid sporophyte (seta) development.

4 core 1 peripheral

Moriya KC, Kono H, Lu YT, Loue-Manifel J, Oka Y, Matsushita T, Honjo MN, Ishizaki K, Kudoh H, Goodrich J, Shimada T. (2026) · Journal of experimental botany  research experimental subject
A bHLH transcription factor (also called MpSMF). Constitutive/steroid-inducible ectopic MpSETA expression in thalli caused air pore/air chamber defects, ectopic pegged rhizoids, and thallus dwarfism, while Mpseta knockouts showed no obvious thallus defect and MpSETA was not detected in wild-type thallus, indicating its native role is mainly in diploid sporophyte (seta) development.
Doll, Y., et al. (2024) · Quantitative Plant Biology  research experimental subject
Subfamily Ia bHLH TF (named MpSETA by Moriya et al., MpSMF by Chang et al.). Knockout abolished elongated setal cells, promoter active in developing setal region, and it interacts with ICE1/SCRM. Concluded to be a pivotal regulator of sporophytic setal development; can partially rescue Arabidopsis mute.
Chang, G., et al. (2023) · Current Biology  research experimental subject
SPEECHLESS/MUTE/FAMA (SMF) bHLH ortholog; the bHLHIIIb regulatory module (MpSMF with MpSCRM1/2) affects epidermis and gametangiophore development, informing the origin of stomata.
Moriya, K. C., et al. (2023) · Nature Plants  research experimental subject
Sole class-Ia bHLH (MpBHLH35; Mp2g04160); regulates cell division/differentiation during seta (sporophyte) development — a stomatal-lineage regulator co-opted in the astomatous liverwort.
Lozano-Quiles M, Raval PK, Rensing SA, Gould SB. (2026) · Plant Reproduction  research experimental background
bHLH transcription factor; downregulated DEG in swi3a/boe-male mutants.

Transcript models

Transcript ID Location Sequences Extract region
Mp2g04160.1 chr2:4788953..4800165 (+) Gene /  mRNA /  CDS /  Protein
FASTA / GenBank (with flanking bases)

Expression Level powered by MBEX

Link to the original image in MBEX


Gene structure:

Sequences:

Gene UTR + CDS + intron

FASTA

mRNA UTR + CDS

FASTA

CDS

FASTA

Protein

FASTA


MarpolBase / Genome Informatics Lab. NIG.