Mp4g12230



Description

Annotation

Database ID Description
FunFam G3DSA:1.10.10.10:FF:000037 Heat stress transcription factor B-4
Gene3D G3DSA:1.10.10.10 -
KEGG K09419 heat shock transcription factor, other eukaryote
KOG KOG0627 Heat shock transcription factor; C-term missing; [K]
MobiDBLite mobidb-lite consensus disorder prediction
PANTHER PTHR10015 HEAT SHOCK TRANSCRIPTION FACTOR
PRINTS PR00056 Heat shock factor (HSF) domain signature
Pfam PF00447 HSF-type DNA-binding
ProSitePatterns PS00434 HSF-type DNA-binding domain signature.
SMART SM00415 hsfneu3
SUPERFAMILY SSF46785 "Winged helix" DNA-binding domain
GO GO:0043565 sequence-specific DNA binding
GO GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO GO:0005634 nucleus
GO GO:0006357 regulation of transcription by RNA polymerase II
GO GO:0003700 DNA-binding transcription factor activity
GO GO:0006355 regulation of DNA-templated transcription
MapolyID Mapoly0011s0205 -

Nomenclature

Gene symbol Product Transcript ID Status
MpHSF1 transcription factor, HSF Published

Associated Literature (AI-based literature mining)

Single-copy HSFB1 of Marchantia; Mphsfb1 CRISPR knockout studied under HS and non-HS conditions. Regulates development (meristem branching, antheridiophore formation, cell division, cell-wall, transporters) with mutants failing to form antheridiophores; induces GABA accumulation under heat, representing the rapidly evolved HSFB subclass.

3 core 2 peripheral

Yadav R, Liu G, Rana P, Pullagurla NJ, Qiu D, Jessen HJ, Laha D. (2025) · PLoS genetics  research experimental subject
Heat shock transcription factor shown by Y2H/BiFC to physically interact with MpIPMK; EMSA showed MpHSFB1 binds the HSE element and MpIPMK potentiates its DNA-binding activity in a dose-dependent manner.
Yen MJ, Lin KH, Thalimaraw L, Yang HR, Boonyaves K, Cheng CY, Wu TY. (2025) · Cell reports  research experimental subject
Heat shock factor B1; distinct role from MpHSFA1 in the heat-stress regulatory network.
Wu, T.-Y., et al. (2022a) · Plant Cell  research experimental subject
Single-copy HSFB1 of Marchantia; Mphsfb1 CRISPR knockout studied under HS and non-HS conditions. Regulates development (meristem branching, antheridiophore formation, cell division, cell-wall, transporters) with mutants failing to form antheridiophores; induces GABA accumulation under heat, representing the rapidly evolved HSFB subclass.
Tan, Q. W., et al. (2023) · Nature Communications  research citation background
Cited as a literature-known gene (Mp4g12230.1) associated with heat tolerance, robustly downregulated under heat stress. Appears only as a DEG/expression-profile entry, not experimentally tested here.
Marchetti, F., et al. (2021) · Plant Cell and Environment  research citation background
Review of M. polymorpha heat-stress response: heat-shock transcription factor among the regulators discussed.

Transcript models

Transcript ID Location Sequences Extract region
Mp4g12230.1 chr4:15371377..15374959 (+) Gene /  mRNA /  CDS /  Protein
FASTA / GenBank (with flanking bases)

Expression Level powered by MBEX

Link to the original image in MBEX

Single-cell expression scRNA-seq atlas from Wang et al., 2023

Expression of Mp4g12230 across the single-cell RNA-seq atlas. Cluster identities (right) annotate the same UMAP used for the feature plot (left).

Feature plot of Mp4g12230 on UMAP
Feature plot (Seurat scale expression level).
UMAP cluster annotation
Cell-type annotation of the UMAP clusters.
Violin plot by developmental stage
Violin plot by stage. Expression across developmental time points (D0–D31).
Violin plot by cell cluster
Violin plot by cluster. Expression across cell clusters (1–21).

Gene structure:

Sequences:

Gene UTR + CDS + intron

FASTA

mRNA UTR + CDS

FASTA

CDS

FASTA

Protein

FASTA

MarpolBase / Genome Informatics Lab. NIG.