Mp1g06440
Description
Annotation
| Database | ID | Description |
|---|---|---|
| MapolyID | Mapoly0043s0036 | - |
Nomenclature
| Gene symbol | Product | Transcript ID | Status |
|---|---|---|---|
| MpFRH1 | miRNA | Published |
Negatively regulates the RSL class I gene MpRSL1
Associated Literature (AI-based literature mining, Beta-version)
Identified by forward-genetic screen of few rhizoids T-DNA mutants and confirmed as a 21-nt miRNA (UGUGUGAGAAGAGGCCAAUGU); overexpression caused very few or no rhizoids in 88/103 plants. Acts as a negative regulator of rhizoid/gemma/mucilage-papilla development by cleaving MpRSL1 mRNA, with a target site 100% conserved across twelve liverworts.
3 core 7 peripheral
Mercadal J, Ferreira-Guerra M, Caño-Delgado AI, Ibañes M. (2026)
· Cell reports research experimental subject
The microRNA FRH1 (MpFRH1) mediates lateral inhibition by repressing RSL1; modeling shows FRH1 diffusion/mobility generates a diffusion-driven switch with a sharp transition between uniform and patterned states, associated with a subcritical Turing bifurcation at criticality.
Thamm, A., et al. (2019)
· BioRxiv research experimental subject
FEW RHIZOIDS1 miRNA; a repressor that inhibits MpRSL1 activity, mediating lateral inhibition to control rhizoid cell patterning. Mpfrh1 loss elevates MpRSL1 and rhizoid numbers.
Honkanen, S., et al. (2018)
· eLIFE research experimental subject
Identified by forward-genetic screen of few rhizoids T-DNA mutants and confirmed as a 21-nt miRNA (UGUGUGAGAAGAGGCCAAUGU); overexpression caused very few or no rhizoids in 88/103 plants. Acts as a negative regulator of rhizoid/gemma/mucilage-papilla development by cleaving MpRSL1 mRNA, with a target site 100% conserved across twelve liverworts.
Aggarwal, B., et al. (2024)
· RNA Biology research citation background
Cited from prior work as FEW RHIZOIDS1, characterized for rhizoid and gemma production control.
Pietrykowska, H., et al. (2023)
· Plant Molecular Biology review citation background
miRNA/tasiRNA target module (Pietrykowska 2023)
Single-cell expression scRNA-seq atlas from Wang et al., 2023
Expression of Mp1g06440 across the single-cell RNA-seq atlas. Cluster identities (right) annotate the same UMAP used for the feature plot (left).
Gene structure:
Sequences: |
Gene UTR + CDS + intron |
| >Mp1g06440.1 GTGTCCCCTG GCCATCCTGA GTATGTTTGT AACTGGAGCA CGCCATCCTA AGGCTACAGT GCGCCAACCC GTGCAGAATC TCCATCTTTG CCCGCTTGCA GCCAAAGAAA ACTGCGTGGC AGTCTATCCG AGTGATGGTG ATGATCCCCT GTGAGGAAGG TGAGGATCCA TGGATGAGGA TGACGCTGGA GCTCATCTCA GAAGACACCA CCTCGTTAGC ACGAGAAAAT TGTGTTCTGT TTCACGCACA ACATAGACCC ACTTACTCTG ACTGACCACT GCTGCTGACT GCGGCTGAAT CGTCCTCGAA TTTAAGGGGT TTTTCCGCTT GGACATTGGC CTCTTCTCAC ACAAACACAG ATGCCACAAG GGTTCGATGT TTGTGCGTGA AGAGACCAAT GTGCAAGCAC AAGAACCGAA AGTGGCCGAA TTCCCTGCTG CAACCTGGAG AATGTCAACA TTTCTGTCTA TCTGTCTATC TATCTAGCTC GCTATCTGTC TGTGTCAGTG ACGGCCGCCA CCACGCGGTG CTGTTTGGCT GTGCTATCTA TTATCTGCGG TTGCTCATCC AATCCAAAAT TCGTGCTGCA GCTTTTGGTT GAATTTCGAT CTGAACGACG CAAATCGTCC ACAAGCCAAG CTGCTGCACG AGCAGAATCG TGGCGCAGCT CAAGCGACTG GAGAGGATCT TAATGCGGTA CACTATGACT ACTACTACAC CACCACCACC ATCACCACGA ACTCCAGCAA CTGCTAGCGC TGGAATTATA CCGGAACTGG ACTAACCAAC TACCCCACCG CCCGCCACGC CGAGCCGAGC TAGCTAGACT GAACTACGGG GCAGGTCTAG GGAGAAGCCG ATGAGAGAAG AGAAGAGGTT CAGATGGGGC CGGCCAGTGG GAAGTCTGGG ACTCTATGGC GCTGTTGAGG GCTGCGGGAG GGGGGAGGGG GGAGGGGGAG ATGAGTGAGC AAGTTCAAGA CTGATGTCGT CTGCTGATGG AAGTACTTAT TTGTACAGAA GAGAGTGCCG AATGATGAGG GAGAAAGAGC GCCTGCGGGC ATTTATATAG GAAGCGAGCG GGTCCGCGCA AAGGGCCGAA CACAGTGCAC GGATGAAGAG GCATGAAAAA TATGGTGGAG TGATGGAGGA GATGAGGGCC TTAGCACTGC AGCAACCACT GTATTAAACG CCAAGTGGGA CTCGGGCGCA GTTATGAGGC CTCACGTTCG CCTCCCCGAG CCTTCCACGT CGCCTACTGC CGTTAATGCC TGGAGTTTTG TTAACTTGCC CCTTAAACAT TCCCGCGCCA CTCTGTTCCC CTCGCCCCAT ATTTAGCCCT AACCCGGCCC CTAATCTTAA CCCTTCCCTG CTTATGGGAC CGCGATTTTC CGATTTTCCC CCTCCATGTG CCCCCTGCTC GCCTGGCCAC CTTTTGCCAG CGCGGATCTA TCGTGGATTG CGCGCCCGTC GTGTTCCAGA ACGTGAAAAT CTCTCAGCTC TCAGCTCTTA GTTCCCCTCC CCTCTCAGCC GCTGCGCTGC GCTCTCTCTT CCCCTCCCCG ACTGTGACGA CTGCGCGCGC CTGCGACCTT CTCCCTGCGA CCTGCGACGA TTATTAGCTC CGGGGGCGGT CGGTTCGTGC CGACGAATTA GACAGCGGAC ACTGCACTTC ACCGGACACG ACTGCCTTTG ACTTGACCGG GACCGGACCA CCGCGCCGCA GCAGCGCCAG TCAGTCAGTA GAGTGAGAAA TGCTCTTGTC CTACAGACAC AGAGAATTGT AGATTCAGAA GGGAAAGAAA GATGCACGCA GTTCTAGAGA GAGAGAGAGA GAGAGAGAGG ATTGACGATG TGAAGCGGAG CCCGTGATTG GGCTTATGGG TGGGATTGAT GAACCTGGAT CAATCCAGGG AGAGGGTGGC ACAAGGTCGA TTCCTTTTTC CGTGACGGGG ATCTCACGTT CGGACATGTC GTGCTTCATA TCTCACGTTC TGTCCTTGTG TGGATCATTA GTGGCAGAGA TTTGCACTAA AACGCTCACG TTGCAGCAGC GCTCGGGGCT AAGTCAGGCG GAATCACACA GGCAGCCTAC GACGGTGAAG GGGAGTCGAC TGTGTGGGCA CATAATTAGA GTTTTCGGTC TCAAGATCAC GTTCTCACAT GTCGACCTAA ATTCATATGT CACGATGTGC GAGTCGAGAA AGGTGTCCTT TCATTTGCAT TAATGTGTAT TTCGCAACGA TAATGGAGCG CCTCTCTACG ACCCAGAGCT TCAATGTGCT TGCACTGGAA AAACGGGTCC TCCGAGCTCG CTGCCCTGCG CTTGGAAAAT CTGGCAAGTC TGACGTGCTC GCCTATCGTG CTTTCACGGC CATTCTCTAG ACAACAGGTC TGCCACTGCT GCAGATCATG TCTGAGTAAT TCAAGGCTGT CACATGTTGC ACCTCAAATG TCACGTTCTT CATGATCGAT ATATAAGGCC TGAACTTACT AGCAGCAGAT CTTGAGGTTT ATGCCTCTGC TTGAAAACGG ACTTCTCGTA CGCTAGGGCT GCCCCGGGTT CCACGATCGT GTCCGTGGCT GTCCTCGAGC AGTAATAAGT TGACAACAAC CGGATGCTGG AACAATTGCG CGTCATTCTC CTGCTTTCCG ACTTAATACG CACCTGTGCT TCGCGAATGC AGAGGATGAT GCCATAACAA TCTCATCCTG CCTTTCGCCG TCACGATCTC TCGACATCGG ATCTCGCATT TGGAATATCA TTCTCGGCTC TTCGACTTAA CTCCCACCCT GACTGGCTTC TGCAAAAAGT GACGCCAGCA TAATCTCACG CGCCCGGCCC TGAGGCTTCA CGAGCTCGTC CCCCACAGAT TCTTAGGTTT TGAATATTCA GATGACAGCT CTGATCCGGC CGCAGCTTTC ACGTGCAACT CTGCGACGCA TTATGTCCAG ATTTTCCCAA AGTTACTCGA GACGGCACAT TTAAACAGGC GCAACTTCAG TCGTCGGCTC GCTGGCTCCA ATCCTCCAAA TCGCTCTAAG TGTGCATCGG GTCCATTCGT GCCTTGAAAA GCTTTCTCCA GATTTGATTC ATGCCTCACG ACCTCTTGTC GGTCTCATAC GGTATCTTCT GTCCACGGTA TTCGCCGGTC AGTAGTTCCT CGTGAAGCTC CTCGTGTCTG ACTCTAGTAA CCCAGAGCCC CTGTAGGTTT CATAGACCCA GCCAGACATA AAGTAACACC GATAAGCTCT AGCATTTTGT TAATCTCCGG AAATTTGCTG CTCAATCTTG GCTTCCCTTC TGACATCACC GGGCGCCCCG AGATCAGAAT CACTCAAAAC TTATCGGATT AGAAAGTAAG TACCTCTATA TCAAAATTCA GACGCTAGAT ATGATTATCA TTCTGTTCAA ACCTTTGAAT GAATGACGTT TCTCTCTTTC CTTTGACTTA TTGATCCAAT CAAATGGATC TGCCGTGTTC GGTATGGCCG ATTGGAGAAA GAGGTTTGTA TTACGTCTTG GGTCGTAGTA GAAATGACAG ATTGCGCTTG ATACTGAAGG TTCTCTCTCA CATTAAATTA ATTTCCAGGT GTGAAGCGGC TGTGTCTCAA CTGCGGACCA TCTGATCCAC AGAGGCAGCT CCAGGCTAGA GTAGATGCAA GAGCACTGAT AGAAATTCGA TGGTTCTAAC TGCTTGAAGA ACAAGATTTT GTTGAGGGCA AAATGTGACT GCTCGACTTT CTGTACGCAA TCTACGAATT TACTGGCGAG AAGGAGGTAA GCTAAGGTCC AAGTTGCTTT GAAAGTCCAG TGCCGACGGT TTAAATTGCG TCCACTTTCG TGAAAATGAT GAGGAAGAAG GTTCTGCAAG AGATTTGTTT CTTCGTTGTC CAACATTGTG CAATCAATGC AAATTTCAAC AGAC |
mRNA UTR + CDS |
| >Mp1g06440.1 GTGTCCCCTG GCCATCCTGA GTATGTTTGT AACTGGAGCA CGCCATCCTA AGGCTACAGT GCGCCAACCC GTGCAGAATC TCCATCTTTG CCCGCTTGCA GCCAAAGAAA ACTGCGTGGC AGTCTATCCG AGTGATGGTG ATGATCCCCT GTGAGGAAGG TGAGGATCCA TGGATGAGGA TGACGCTGGA GCTCATCTCA GAAGACACCA CCTCGTTAGC ACGAGAAAAT TGTGTTCTGT TTCACGCACA ACATAGACCC ACTTACTCTG ACTGACCACT GCTGCTGACT GCGGCTGAAT CGTCCTCGAA TTTAAGGGGT TTTTCCGCTT GGACATTGGC CTCTTCTCAC ACAAACACAG ATGCCACAAG GGTTCGATGT TTGTGCGTGA AGAGACCAAT GTGCAAGCAC AAGAACCGAA AGTGGCCGAA TTCCCTGCTG CAACCTGGAG AATGTCAACA TTTCTGTCTA TCTGTCTATC TATCTAGCTC GCTATCTGTC TGTGTCAGTG ACGGCCGCCA CCACGCGGTG CTGTTTGGCT GTGCTATCTA TTATCTGCGG TTGCTCATCC AATCCAAAAT TCGTGCTGCA GCTTTTGGTT GAATTTCGAT CTGAACGACG CAAATCGTCC ACAAGCCAAG CTGCTGCACG AGCAGAATCG TGGCGCAGCT CAAGCGACTG GAGAGGATCT TAATGCGGTA CACTATGACT ACTACTACAC CACCACCACC ATCACCACGA ACTCCAGCAA CTGCTAGCGC TGGAATTATA CCGGAACTGG ACTAACCAAC TACCCCACCG CCCGCCACGC CGAGCCGAGC TAGCTAGACT GAACTACGGG GCAGGTCTAG GGAGAAGCCG ATGAGAGAAG AGAAGAGGTT CAGATGGGGC CGGCCAGTGG GAAGTCTGGG ACTCTATGGC GCTGTTGAGG GCTGCGGGAG GGGGGAGGGG GGAGGGGGAG ATGAGTGAGC AAGTTCAAGA CTGATGTCGT CTGCTGATGG AAGTACTTAT TTGTACAGAA GAGAGTGCCG AATGATGAGG GAGAAAGAGC GCCTGCGGGC ATTTATATAG GAAGCGAGCG GGTCCGCGCA AAGGGCCGAA CACAGTGCAC GGATGAAGAG GCATGAAAAA TATGGTGGAG TGATGGAGGA GATGAGGGCC TTAGCACTGC AGCAACCACT GTATTAAACG CCAAGTGGGA CTCGGGCGCA GTTATGAGGC CTCACGTTCG CCTCCCCGAG CCTTCCACGT CGCCTACTGC CGTTAATGCC TGGAGTTTTG TTAACTTGCC CCTTAAACAT TCCCGCGCCA CTCTGTTCCC CTCGCCCCAT ATTTAGCCCT AACCCGGCCC CTAATCTTAA CCCTTCCCTG CTTATGGGAC CGCGATTTTC CGATTTTCCC CCTCCATGTG CCCCCTGCTC GCCTGGCCAC CTTTTGCCAG CGCGGATCTA TCGTGGATTG CGCGCCCGTC GTGTTCCAGA ACGTGAAAAT CTCTCAGCTC TCAGCTCTTA GTTCCCCTCC CCTCTCAGCC GCTGCGCTGC GCTCTCTCTT CCCCTCCCCG ACTGTGACGA CTGCGCGCGC CTGCGACCTT CTCCCTGCGA CCTGCGACGA TTATTAGCTC CGGGGGCGGT CGGTTCGTGC CGACGAATTA GACAGCGGAC ACTGCACTTC ACCGGACACG ACTGCCTTTG ACTTGACCGG GACCGGACCA CCGCGCCGCA GCAGCGCCAG TCAGTCAGTA GAGTGAGAAA TGCTCTTGTC CTACAGACAC AGAGAATTGT AGATTCAGAA GGGAAAGAAA GATGCACGCA GTTCTAGAGA GAGAGAGAGA GAGAGAGAGG ATTGACGATG TGAAGCGGAG CCCGTGATTG GGCTTATGGG TGGGATTGAT GAACCTGGAT CAATCCAGGG AGAGGGTGGC ACAAGGTCGA TTCCTTTTTC CGTGACGGGG ATCTCACGTT CGGACATGTC GTGCTTCATA TCTCACGTTC TGTCCTTGTG TGGATCATTA GTGGCAGAGA TTTGCACTAA AACGCTCACG TTGCAGCAGC GCTCGGGGCT AAGTCAGGCG GAATCACACA GGCAGCCTAC GACGGTGAAG GGGAGTCGAC TGTGTGGGCA CATAATTAGA GTTTTCGGTC TCAAGATCAC GTTCTCACAT GTCGACCTAA ATTCATATGT CACGATGTGC GAGTCGAGAA AGGTGTCCTT TCATTTGCAT TAATGTGTAT TTCGCAACGA TAATGGAGCG CCTCTCTACG ACCCAGAGCT TCAATGTGCT TGCACTGGAA AAACGGGTCC TCCGAGCTCG CTGCCCTGCG CTTGGAAAAT CTGGCAAGTC TGACGTGCTC GCCTATCGTG CTTTCACGGC CATTCTCTAG ACAACAGGTC TGCCACTGCT GCAGATCATG TCTGAGTAAT TCAAGGCTGT CACATGTTGC ACCTCAAATG TCACGTTCTT CATGATCGAT ATATAAGGCC TGAACTTACT AGCAGCAGAT CTTGAGGTTT ATGCCTCTGC TTGAAAACGG ACTTCTCGTA CGCTAGGGCT GCCCCGGGTT CCACGATCGT GTCCGTGGCT GTCCTCGAGC AGTAATAAGT TGACAACAAC CGGATGCTGG AACAATTGCG CGTCATTCTC CTGCTTTCCG ACTTAATACG CACCTGTGCT TCGCGAATGC AGAGGATGAT GCCATAACAA TCTCATCCTG CCTTTCGCCG TCACGATCTC TCGACATCGG ATCTCGCATT TGGAATATCA TTCTCGGCTC TTCGACTTAA CTCCCACCCT GACTGGCTTC TGCAAAAAGT GACGCCAGCA TAATCTCACG CGCCCGGCCC TGAGGCTTCA CGAGCTCGTC CCCCACAGAT TCTTAGGTTT TGAATATTCA GATGACAGCT CTGATCCGGC CGCAGCTTTC ACGTGCAACT CTGCGACGCA TTATGTCCAG ATTTTCCCAA AGTTACTCGA GACGGCACAT TTAAACAGGC GCAACTTCAG TCGTCGGCTC GCTGGCTCCA ATCCTCCAAA TCGCTCTAAG TGTGCATCGG GTCCATTCGT GCCTTGAAAA GCTTTCTCCA GATTTGATTC ATGCCTCACG ACCTCTTGTC GGTCTCATAC GGTATCTTCT GTCCACGGTA TTCGCCGGTC AGTAGTTCCT CGTGAAGCTC CTCGTGTCTG ACTCTAGTAA CCCAGAGCCC CTGTAGGTTT CATAGACCCA GCCAGACATA AAGTAACACC GATAAGCTCT AGCATTTTGT TAATCTCCGG AAATTTGCTG CTCAATCTTG GCTTCCCTTC TGACATCACC GGGCGCCCCG AGATCAGAAT CACTCAAAAC TTATCGGATT AGAAAGTGTG AAGCGGCTGT GTCTCAACTG CGGACCATCT GATCCACAGA GGCAGCTCCA GGCTAGAGTA GATGCAAGAG CACTGATAGA AATTCGATGG TTCTAACTGC TTGAAGAACA AGATTTTGTT GAGGGCAAAA TGTGACTGCT CGACTTTCTG TACGCAATCT ACGAATTTAC TGGCGAGAAG GAGGTAAGCT AAGGTCCAAG TTGCTTTGAA AGTCCAGTGC CGACGGTTTA AATTGCGTCC ACTTTCGTGA AAATGATGAG GAAGAAGGTT CTGCAAGAGA TTTGTTTCTT CGTTGTCCAA CATTGTGCAA TCAATGCAAA TTTCAACAGA C |
CDS |
| >Mp1g06440.1 ATGGGTGGGA TTGATGAACC TGGATCAATC CAGGGAGAGG GTGGCACAAG GTCGATTCCT TTTTCCGTGA CGGGGATCTC ACGTTCGGAC ATGTCGTGCT TCATATCTCA CGTTCTGTCC TTGTGTGGAT CATTAGTGGC AGAGATTTGC ACTAAAACGC TCACGTTGCA GCAGCGCTCG GGGCTAAGTC AGGCGGAATC ACACAGGCAG CCTACGACGG TGAAGGGGAG TCGACTGTGT GGGCACATAA TTAGAGTTTT CGGTCTCAAG ATCACGTTCT CACATGTCGA CCTAAATTCA TATGTCACGA TGTGCGAGTC GAGAAAGGTG TCCTTTCATT TGCATTAA |
Protein |
| >Mp1g06440.1 MGGIDEPGSI QGEGGTRSIP FSVTGISRSD MSCFISHVLS LCGSLVAEIC TKTLTLQQRS GLSQAESHRQ PTTVKGSRLC GHIIRVFGLK ITFSHVDLNS YVTMCESRKV SFHLH |