Mp3g22920



Description

Annotation

Database ID Description
CDD cd19513 Rad51
FunFam G3DSA:1.10.150.20:FF:000008 DNA repair protein RAD51 homolog
FunFam G3DSA:3.40.50.300:FF:000092 DNA repair protein Rad51 homolog
Gene3D G3DSA:1.10.150.20 -
Gene3D G3DSA:3.40.50.300 -
KEGG K04482 DNA repair protein RAD51
KOG KOG1434 Meiotic recombination protein Dmc1; [DL]
MobiDBLite mobidb-lite consensus disorder prediction
NCBIfam TIGR02239 DNA repair protein RAD51
PANTHER PTHR22942 RECA/RAD51/RADA DNA STRAND-PAIRING FAMILY MEMBER
PIRSF PIRSF005856 Rad51
Pfam PF08423 Rad51
Pfam PF14520 Helix-hairpin-helix domain
ProSiteProfiles PS50162 RecA family profile 1.
ProSiteProfiles PS50163 RecA family profile 2.
SMART SM00382 AAA_5
SUPERFAMILY SSF47794 Rad51 N-terminal domain-like
SUPERFAMILY SSF52540 P-loop containing nucleoside triphosphate hydrolases
GO GO:0006312 mitotic recombination
GO GO:0000166 nucleotide binding
GO GO:0003697 single-stranded DNA binding
GO GO:0000730 DNA recombinase assembly
GO GO:0042148 DNA strand invasion
GO GO:0000150 DNA strand exchange activity
GO GO:0016887 ATP hydrolysis activity
GO GO:0000794 condensed nuclear chromosome
GO GO:0000724 double-strand break repair via homologous recombination
GO GO:0007131 reciprocal meiotic recombination
GO GO:0005524 ATP binding
GO GO:0003690 double-stranded DNA binding
GO GO:0140664 ATP-dependent DNA damage sensor activity
GO GO:0070192 chromosome organization involved in meiotic cell cycle
GO GO:0006281 DNA repair
GO GO:1990426 mitotic recombination-dependent replication fork processing
GO GO:0008094 ATP-dependent activity, acting on DNA
GO GO:0003677 DNA binding
GO GO:0006259 DNA metabolic process
MapolyID Mapoly0024s0069 -

Nomenclature

Gene symbol Product Transcript ID Status
MpRAD51 RAD51 DNA recombinase Published
Locus assigned by MarpolBase literature-mining curation (2026-10): Accession list of PMID 42203494: "MpRAD51 (Mp3g22920)"; the locus is annotated KEGG K04482 (RAD51).

Associated Literature (AI-based literature mining)

This study functionally characterized MpRAD51, the M. polymorpha ortholog of the homologous-recombination recombinase RAD51. Its DNA-repair functions were confirmed biochemically, and loss of MpRAD51 revealed a role in regulating DNA-damage-induced development and differentiation, preventing growth arrest under genotoxic conditions.

1 core 0 peripheral

Trujillo-Esquivel E, Lorenzo-Manzanarez JL, Espinal-Centeno A, Méndez-Alvarez D, Aguilar-Cruz A, Brieba LG, Cruz-Ramírez A. (2026) · The Plant cell  research experimental subject
This study functionally characterized MpRAD51, the M. polymorpha ortholog of the homologous-recombination recombinase RAD51. Its DNA-repair functions were confirmed biochemically, and loss of MpRAD51 revealed a role in regulating DNA-damage-induced development and differentiation, preventing growth arrest under genotoxic conditions.

Transcript models

Transcript ID Location Sequences Extract region
Mp3g22920.1 chr3:25874378..25877766 (-) Gene /  mRNA /  CDS /  Protein
FASTA / GenBank (with flanking bases)

Expression Level powered by MBEX

Link to the original image in MBEX

Single-cell expression scRNA-seq atlas from Wang et al., 2023

Expression of Mp3g22920 across the single-cell RNA-seq atlas. Cluster identities (right) annotate the same UMAP used for the feature plot (left).

Feature plot of Mp3g22920 on UMAP
Feature plot (Seurat scale expression level).
UMAP cluster annotation
Cell-type annotation of the UMAP clusters.
Violin plot by developmental stage
Violin plot by stage. Expression across developmental time points (D0–D31).
Violin plot by cell cluster
Violin plot by cluster. Expression across cell clusters (1–21).

Gene structure:

Sequences:

Gene UTR + CDS + intron

FASTA

mRNA UTR + CDS

FASTA

CDS

FASTA

Protein

FASTA

MarpolBase / Genome Informatics Lab. NIG.