Mp5g06550



Description

Annotation

Database ID Description
FunFam G3DSA:1.20.58.2010:FF:000001 Rop guanine nucleotide exchange factor 14
FunFam G3DSA:1.20.58.2010:FF:000003 Rop guanine nucleotide exchange factor 14
Gene3D G3DSA:1.20.58.2010 PRONE domain, subdomain 1
KOG KOG4020 Protein DRE2, required for cell viability; N-term missing; C-term missing; [S]
MobiDBLite mobidb-lite consensus disorder prediction
PANTHER PTHR33101 ROP GUANINE NUCLEOTIDE EXCHANGE FACTOR 1
Pfam PF03759 PRONE (Plant-specific Rop nucleotide exchanger)
ProSiteProfiles PS51334 PRONE domain profile.
GO GO:0005085 guanyl-nucleotide exchange factor activity
MapolyID Mapoly0171s0028 -

Nomenclature

Gene symbol Product Transcript ID Status
MpKAR RopGEF Published
MpKARAPPO PRONE-type guanine nucleotide exchange factor for ROP GTPase, gemmae cup Provisional
Essential in the initiation of plantlet development from a differentiated cell

Associated Literature (AI-based literature mining)

Encoded by the karappo (kar) gene; upstream activator of MpROP. Interacts with MpROP by yeast two-hybrid, and kar mutants phenocopy gemma defects; the Mprop-1 switch II mutation blocks MpROPGEF binding.

2 core 2 peripheral

Rong, D., et al. (2022) · PNAS  research experimental subject
Encoded by the karappo (kar) gene; upstream activator of MpROP. Interacts with MpROP by yeast two-hybrid, and kar mutants phenocopy gemma defects; the Mprop-1 switch II mutation blocks MpROPGEF binding.
Hiwatashi, T., et al. (2019) · Current Biology   experimental subject
Causal gene identified in karappo mutants; encodes a RopGEF with PRONE domain essential for initiating gemma development via ROP signaling.
Mulvey, H., et al. (2023) · Current Biology  research experimental comparator
ROP guanine-nucleotide exchange factor; positive regulator of MpROP required to initiate gemma development.
Iwata KP, Shimizu T, Sakai Y, Furuya T, Fukumura H, Kondo Y, Masuda T, Ishizaki K, Fukaki H. (2025) · The New phytologist  research experimental background
KARAPPO expression was unchanged in Mprlf-ge mutants in RNA-seq.

Transcript models

Transcript ID Location Sequences Extract region
Mp5g06550.2 chr5:8700389..8707285 (-) Gene /  mRNA /  CDS /  Protein
FASTA / GenBank (with flanking bases)
Mp5g06550.1 chr5:8701700..8707320 (-) Gene /  mRNA /  CDS /  Protein
FASTA / GenBank (with flanking bases)

Expression Level powered by MBEX

Link to the original image in MBEX

Single-cell expression scRNA-seq atlas from Wang et al., 2023

Expression of Mp5g06550 across the single-cell RNA-seq atlas. Cluster identities (right) annotate the same UMAP used for the feature plot (left).

Feature plot of Mp5g06550 on UMAP
Feature plot (Seurat scale expression level).
UMAP cluster annotation
Cell-type annotation of the UMAP clusters.
Violin plot by developmental stage
Violin plot by stage. Expression across developmental time points (D0–D31).
Violin plot by cell cluster
Violin plot by cluster. Expression across cell clusters (1–21).

Gene structure:

Sequences:

Gene UTR + CDS + intron

FASTA

mRNA UTR + CDS

FASTA

CDS

FASTA

Protein

FASTA

Gene structure:

Sequences:

Gene UTR + CDS + intron

FASTA

mRNA UTR + CDS

FASTA

CDS

FASTA

Protein

FASTA


MarpolBase / Genome Informatics Lab. NIG.