Mp5g17740



Description

Annotation

Database ID Description
PANTHER PTHR45747 HISTONE-LYSINE N-METHYLTRANSFERASE E(Z)
ProSiteProfiles PS51633 CXC domain profile.
CDD cd10519 SET_EZH
SMART SM01114 CXC_2
Pfam PF18264 CXC domain
Gene3D G3DSA:2.170.270.10 SET domain
Coils Coil Coil
FunFam G3DSA:2.170.270.10:FF:000001 Putative histone-lysine N-methyltransferase EZH2
SMART SM00317 set_7
ProSiteProfiles PS50280 SET domain profile.
SUPERFAMILY SSF82199 SET domain
Pfam PF00856 SET domain
KOG KOG1079 Transcriptional repressor EZH1; N-term missing; [K]
MapolyID Mapoly0084s0024 -
GO GO:0005634 nucleus
GO GO:0006338 chromatin remodeling
GO GO:0005515 protein binding
GO GO:0031507 heterochromatin formation
GO GO:0042054 histone methyltransferase activity
GO GO:0046976 histone H3K27 methyltransferase activity
GO GO:0003682 chromatin binding

Nomenclature

Gene symbol Product Transcript ID Status
MpE(z)2 E(z)2 Published

Associated Literature (AI-based literature mining, Beta-version)

PRC2 catalytic subunit; CRISPR/Cas9 dual knockout with MpE(z)3 in females, profiled by transcriptome and CUT&RUN. Maternal inheritance is essential for paternal H3K27me3 deposition. Loss reduces H3K27me3, reactivates paternal genes, drops embryo survival to ~20% and abolishes viable spores.

1 core 0 peripheral

Montgomery, S. A., et al. (2022) · eLife  research experimental subject
PRC2 catalytic subunit; CRISPR/Cas9 dual knockout with MpE(z)3 in females, profiled by transcriptome and CUT&RUN. Maternal inheritance is essential for paternal H3K27me3 deposition. Loss reduces H3K27me3, reactivates paternal genes, drops embryo survival to ~20% and abolishes viable spores.

Transcript models

Transcript ID Location Sequences Extract region
Mp5g17740.1 chr5:21943434..21950554 (+) Gene /  mRNA /  CDS /  Protein
FASTA / GenBank (with flanking bases)
Mp5g17740.2 chr5:21943434..21950554 (+) Gene /  mRNA /  CDS /  Protein
FASTA / GenBank (with flanking bases)

Expression Level powered by MBEX

Link to the original image in MBEX

Single-cell expression scRNA-seq atlas from Wang et al., 2023

Expression of Mp5g17740 across the single-cell RNA-seq atlas. Cluster identities (right) annotate the same UMAP used for the feature plot (left).

Feature plot of Mp5g17740 on UMAP
Feature plot (Seurat scale expression level).
UMAP cluster annotation
Cell-type annotation of the UMAP clusters.
Violin plot by developmental stage
Violin plot by stage. Expression across developmental time points (D0–D31).
Violin plot by cell cluster
Violin plot by cluster. Expression across cell clusters (1–21).

Gene structure:

Sequences:

Gene UTR + CDS + intron

FASTA

mRNA UTR + CDS

FASTA

CDS

FASTA

Protein

FASTA

Gene structure:

Sequences:

Gene UTR + CDS + intron

FASTA

mRNA UTR + CDS

FASTA

CDS

FASTA

Protein

FASTA


MarpolBase / Genome Informatics Lab. NIG.