Mp7g11720



Description

Annotation

Database ID Description
CDD cd00593 RIBOc
CDD cd18034 DEXHc_dicer
CDD cd19869 DSRM_DCL_plant
FunFam G3DSA:1.10.1520.10:FF:000004 Endoribonuclease dicer-like 1
FunFam G3DSA:3.30.160.380:FF:000001 Endoribonuclease dicer-like 1
FunFam G3DSA:3.40.50.300:FF:000705 Endoribonuclease dicer-like protein
Gene3D G3DSA:1.10.1520.10 Ribonuclease III domain
Gene3D G3DSA:2.170.260.10 paz domain
Gene3D G3DSA:3.30.160.20 -
Gene3D G3DSA:3.30.160.380 Dicer dimerisation domain
Gene3D G3DSA:3.40.50.300 -
KEGG K11592 endoribonuclease Dicer [EC:3.1.26.-]
KOG KOG0701 dsRNA-specific nuclease Dicer and related ribonucleases; [A]
MobiDBLite mobidb-lite consensus disorder prediction
PANTHER PTHR14950 DICER-RELATED
Pfam PF00271 Helicase conserved C-terminal domain
Pfam PF00636 Ribonuclease III domain
Pfam PF02170 PAZ domain
Pfam PF03368 Dicer dimerisation domain
Pfam PF04851 Type III restriction enzyme, res subunit
Pfam PF14709 double strand RNA binding domain from DEAD END PROTEIN 1
ProSitePatterns PS00517 Ribonuclease III family signature.
ProSiteProfiles PS50142 Ribonuclease III family domain profile.
ProSiteProfiles PS50821 PAZ domain profile.
ProSiteProfiles PS51192 Superfamilies 1 and 2 helicase ATP-binding type-1 domain profile.
ProSiteProfiles PS51194 Superfamilies 1 and 2 helicase C-terminal domain profile.
ProSiteProfiles PS51327 Dicer double-stranded RNA-binding fold domain profile.
SMART SM00358 DRBM_3
SMART SM00487 ultradead3
SMART SM00490 helicmild6
SMART SM00535 riboneu5
SMART SM00949 PAZ_2_a_3
SUPERFAMILY SSF101690 PAZ domain
SUPERFAMILY SSF52540 P-loop containing nucleoside triphosphate hydrolases
SUPERFAMILY SSF54768 dsRNA-binding domain-like
SUPERFAMILY SSF69065 RNase III domain-like
GO GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters
GO GO:0005634 nucleus
GO GO:0003723 RNA binding
GO GO:0016787 hydrolase activity
GO GO:0005524 ATP binding
GO GO:0006396 RNA processing
GO GO:0030422 siRNA processing
GO GO:0005515 protein binding
GO GO:0004525 ribonuclease III activity
GO GO:0003677 DNA binding
GO GO:0005737 cytoplasm
MapolyID Mapoly0003s0184 -

Nomenclature

Gene symbol Product Transcript ID Status
MpDCL4 miRNA biogenesis protein Provisional

Associated Literature (AI-based literature mining)

Upregulated upon TMV infection. Proposed as the main antiviral DCL in Marchantia given the absence of a DCL2 gene. TMV-derived vsRNAs were enriched in 21-nt fragments consistent with DCL4-mediated processing.

4 core 3 peripheral

Csicsely, E., et al. (2025) · The Plant Journal  research experimental subject
Full-domain DCL; mutant lacks inducible gametangiophores, salt/ABA hypersensitive, loses MpTAS3 ta-siRNAs; ta-siRNA biogenesis role.
Hung, Y.-L., et al. (2024) · Plant & Cell Physiology  research experimental subject
DICER-LIKE4; processes MpTAS3 dsRNA to generate the tasiRNAs that regulate MpCYP78A101.
Ros-Moner, E., et al. (2024) · Nature Communications  research experimental subject
Upregulated upon TMV infection. Proposed as the main antiviral DCL in Marchantia given the absence of a DCL2 gene. TMV-derived vsRNAs were enriched in 21-nt fragments consistent with DCL4-mediated processing.
Tsuzuki, M., et al. (2016) · Plant and Cell Physiology  research experimental subject
DICER-LIKE4; sRNA-biogenesis component.
Balcerowicz M. (2025) · The Plant journal : for cell and molecular biology  other citation background
DICER-LIKE gene discussed as part of the MpDCL family essential for reproductive development.

Transcript models

Transcript ID Location Sequences Extract region
Mp7g11720.1 chr7:14940682..14970037 (-) Gene /  mRNA /  CDS /  Protein
FASTA / GenBank (with flanking bases)

Expression Level powered by MBEX

Link to the original image in MBEX

Single-cell expression scRNA-seq atlas from Wang et al., 2023

Expression of Mp7g11720 across the single-cell RNA-seq atlas. Cluster identities (right) annotate the same UMAP used for the feature plot (left).

Feature plot of Mp7g11720 on UMAP
Feature plot (Seurat scale expression level).
UMAP cluster annotation
Cell-type annotation of the UMAP clusters.
Violin plot by developmental stage
Violin plot by stage. Expression across developmental time points (D0–D31).
Violin plot by cell cluster
Violin plot by cluster. Expression across cell clusters (1–21).

Gene structure:

Sequences:

Gene UTR + CDS + intron

FASTA

mRNA UTR + CDS

FASTA

CDS

FASTA

Protein

FASTA

MarpolBase / Genome Informatics Lab. NIG.