Mp7g12670



Description

Annotation

Database ID Description
SUPERFAMILY SSF57850 RING/U-box
Coils Coil Coil
Pfam PF13923 Zinc finger, C3HC4 type (RING finger)
MobiDBLite mobidb-lite consensus disorder prediction
Gene3D G3DSA:3.30.40.10 Zinc/RING finger domain, C3HC4 (zinc finger)
Gene3D G3DSA:3.10.20.90 -
ProSitePatterns PS00518 Zinc finger RING-type signature.
PANTHER PTHR46293 E3 UBIQUITIN PROTEIN LIGASE DRIP1
ProSiteProfiles PS50089 Zinc finger RING-type profile.
SMART SM00184 ring_2
CDD cd16525 RING-HC_PCGF
KEGG K16277 E3 ubiquitin-protein ligase DRIP [EC:2.3.2.27]
KOG KOG2660 Locus-specific chromosome binding proteins; C-term missing; [S]
MapolyID Mapoly0003s0275 -
GO GO:0004842 ubiquitin-protein transferase activity

Nomenclature

Gene symbol Product Transcript ID Status
MpBMI1 Chromatin related protein Provisional

Associated Literature (AI-based literature mining, Beta-version)

Core PRC1 RING-finger E3 ligase (Mp7g12670) identified by BLAST; CRISPR knockout combined with Mpbmi1l caused strongly reduced growth and gemma-cup defects, global H2Aub loss by western blot, and altered H2Aub/H3K27me3 by ChIP-seq, showing it deposits H2Aub for Polycomb gene repression.

1 core 0 peripheral

Liu, S., et al. (2021b) · Genome Biology  research experimental subject
Core PRC1 RING-finger E3 ligase (Mp7g12670) identified by BLAST; CRISPR knockout combined with Mpbmi1l caused strongly reduced growth and gemma-cup defects, global H2Aub loss by western blot, and altered H2Aub/H3K27me3 by ChIP-seq, showing it deposits H2Aub for Polycomb gene repression.

Transcript models

Transcript ID Location Sequences Extract region
Mp7g12670.1 chr7:15883691..15889320 (+) Gene /  mRNA /  CDS /  Protein
FASTA / GenBank (with flanking bases)

Expression Level powered by MBEX

Link to the original image in MBEX

Single-cell expression scRNA-seq atlas from Wang et al., 2023

Expression of Mp7g12670 across the single-cell RNA-seq atlas. Cluster identities (right) annotate the same UMAP used for the feature plot (left).

Feature plot of Mp7g12670 on UMAP
Feature plot (Seurat scale expression level).
UMAP cluster annotation
Cell-type annotation of the UMAP clusters.
Violin plot by developmental stage
Violin plot by stage. Expression across developmental time points (D0–D31).
Violin plot by cell cluster
Violin plot by cluster. Expression across cell clusters (1–21).

Gene structure:

Sequences:

Gene UTR + CDS + intron

FASTA

mRNA UTR + CDS

FASTA

CDS

FASTA

Protein

FASTA


MarpolBase / Genome Informatics Lab. NIG.