Mp8g00080



Description

Annotation

Database ID Description
ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2.
SUPERFAMILY SSF51735 NAD(P)-binding Rossmann-fold domains
MobiDBLite mobidb-lite consensus disorder prediction
PANTHER PTHR43254 C-TERMINAL BINDING PROTEIN AN-RELATED
Gene3D G3DSA:3.40.50.720 -
Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
KOG KOG0067 Transcription factor CtBP; C-term missing; [K]
MapolyID Mapoly0077s0060 -
GO GO:0051287 NAD binding
GO GO:0000226 microtubule cytoskeleton organization

Nomenclature

Gene symbol Product Transcript ID Status
MpAN Polarization Provisional

Associated Literature (AI-based literature mining, Beta-version)

A knockout mutant (Mpan-1ko) and its complementation line (pMpAN:MpAN-1/Mpan-1ko) were generated and used as test material. The Mpan-1ko mutant shows a thallus twisted along the growth axis, relatively uniform among individuals, while the complementation line resembles WT (Tak-1). MpAN function was studied via its loss-of-function morphological phenotype to validate the 3D quantification method.

3 core 1 peripheral

Furuya, T., et al. (2019) · Frontiers in Plant Science  research experimental subject
A knockout mutant (Mpan-1ko) and its complementation line (pMpAN:MpAN-1/Mpan-1ko) were generated and used as test material. The Mpan-1ko mutant shows a thallus twisted along the growth axis, relatively uniform among individuals, while the complementation line resembles WT (Tak-1). MpAN function was studied via its loss-of-function morphological phenotype to validate the 3D quantification method.
Furuya, T., et al. (2018) · Development  research experimental subject
ANGUSTIFOLIA (CtBP/BARS-like); contributes to three-dimensional morphogenesis. Mpan knockouts show abnormal twisted thalli and suppressed growth; complementation restores wild type; MpAN-Citrine localization analyzed.
Minamisawa N, Sato M, Cho KH, Ueno H, Takechi K, Kajikawa M, Yamato KT, Ohyama K, Toyooka K, Kim GT, Horiguchi G, Takano H, Ueda T, Tsukaya H. (2011) · Plant J  research experimental subject
Marchantia ANGUSTIFOLIA ortholog (named MAN in the paper); 35S-driven MAN fully complemented the Arabidopsis an-1 mutant despite lacking the canonical nuclear localization signal, supporting a non-nuclear (Golgi-associated) function for ANGUSTIFOLIA.
Furuya, T., et al. (2021) · Journal of Plant Research  research experimental comparator
Compared as a cross-species/functional partner: Mpan mutants show twisted thalli and suppressed growth, with cortical microtubule defects partially overlapping but opposite in cell-circularity effect to Mpdyrkp.

Expression Level powered by MBEX

Link to the original image in MBEX

Transcript models

Transcript ID Location Sequences Extract region
Mp8g00080.1 chr8:113851..118926 (-) Gene /  mRNA /  CDS /  Protein
FASTA / GenBank (with flanking bases)

Gene structure:

Sequences:

Gene UTR + CDS + intron

FASTA

mRNA UTR + CDS

FASTA

CDS

FASTA

Protein

FASTA


MarpolBase / Genome Informatics Lab. NIG.