Mp8g03070
Description
Annotation
| Database | ID | Description |
|---|---|---|
| CDD | cd02440 | AdoMet_MTases |
| Coils | Coil | Coil |
| FunFam | G3DSA:3.40.50.150:FF:000088 | Polyamine aminopropyltransferase |
| Gene3D | G3DSA:2.30.140.10 | Spermidine synthase, tetramerisation domain |
| Gene3D | G3DSA:3.40.50.150 | Vaccinia Virus protein VP39 |
| Hamap | MF_00198 | Polyamine aminopropyltransferase [speE]. |
| KEGG | K00797 | spermidine synthase [EC:2.5.1.16] |
| KEGG | K18787 | thermospermine synthase [EC:2.5.1.79] |
| KOG | KOG1562 | Spermidine synthase; C-term missing; [E] |
| NCBIfam | NF037959 | fused MFS/spermidine synthase |
| PANTHER | PTHR43317 | THERMOSPERMINE SYNTHASE ACAULIS5 |
| Pfam | PF01564 | Spermine/spermidine synthase domain |
| Pfam | PF17284 | Spermidine synthase tetramerisation domain |
| ProSiteProfiles | PS51006 | Polyamine biosynthesis (PABS) domain profile. |
| SUPERFAMILY | SSF53335 | S-adenosyl-L-methionine-dependent methyltransferases |
| GO | GO:0010487 | thermospermine synthase activity |
| GO | GO:0003824 | catalytic activity |
| GO | GO:0006596 | polyamine biosynthetic process |
| MapolyID | Mapoly0012s0100 | - |
Nomenclature
| Gene symbol | Product | Transcript ID | Status |
|---|---|---|---|
| MpACL5 | Thermospermine synthase (ACAULIS5) | Published |
Locus assigned by MarpolBase literature-mining curation (2026-10): GenBank LC761627 (MpACL5 mRNA) matches this locus exactly.
Associated Literature (AI-based literature mining)
Central gene of the study, encoding thermospermine synthase; M. polymorpha ACL5 rescues the dwarf acl5 mutant of Arabidopsis. Loss-of-function mutants were generated and analyzed, showing roles in organ development of thalli and reproductive organs, suppression of gametangiophore fasciation, and stress responses. Preferentially expressed in meristematic regions; characterized by mutant phenotyping, expression analysis, and complementation.
2 core 0 peripheral
Solé-Gil A, Sakai Y, Catarino B, Jones VAS, Youngstrom CE, Jordà-Segura J, Cheng CL, Dolan L, Ambrose BA, Ishizaki K, Blázquez MA, Agustí J. (2025)
· Developmental cell research experimental subject
Thermospermine synthase ACL5; MpACL5 controls dichotomous branching by regulating meristematic activity in M. polymorpha, defining a thermospermine-dependent regulatory pathway whose evolution diverged in land plants.
Furumoto, T., et al. (2024)
· Plant & Cell Physiology research experimental subject
Central gene of the study, encoding thermospermine synthase; M. polymorpha ACL5 rescues the dwarf acl5 mutant of Arabidopsis. Loss-of-function mutants were generated and analyzed, showing roles in organ development of thalli and reproductive organs, suppression of gametangiophore fasciation, and stress responses. Preferentially expressed in meristematic regions; characterized by mutant phenotyping, expression analysis, and complementation.
Single-cell expression scRNA-seq atlas from Wang et al., 2023
Expression of Mp8g03070 across the single-cell RNA-seq atlas. Cluster identities (right) annotate the same UMAP used for the feature plot (left).
Gene structure:
Sequences: |
Gene UTR + CDS + intron |
| >Mp8g03070.1 GGTCAGCTTC CTTGCTCCCG TCCTCGCTTG CTTTGTTTGG GAGGTTGTTG CTACCACTCT TCCAGCCGCA GCTCCTGCTC CTTCGCCAAC AACGCTCGCC GCTTTCCACG ACTCCTAGTC TTCGGGAATT TGCTTTTCTG CTGAAGCAAC AGGTCCACTT CTTTCGTGCA CTCGGCGAAA GCAGGGCCTC CTCACCTCCT GTTCCTCTCC TTGCAAGCCT TGTGTTGGAG TTCTCGTCTC TGAGCCGCTT CTAGACGTCC TGTCTGTGTT GTTTATTTCA AGCAGTCGGT GGAGGAATCG GGGAGTGTTG GTCAATTCGT TCGTCGTTTT CTCGCTGCAA TTGACCGTGA ACGGTCAGAG AGACCATTTC TGCTCTGTTT TCTTTCTTTA TTAAGTCTTC AGTATCCTGG TTGCCGCTGT TGTAACGTTG CTGCTTCGTT CGTTCGAATT CTCTCCTGTG AGCTCGTCAT CCTGTAAGTA AAGCTGGGGA AGGAAAGCCT CCCAGGTCGG GGAAAGGAAA GAGAGGACGA AATGGCTGAA GCCATTACGA CTACAACCAC GATTCACCTG AATGGTTCAG CTCCCACCAA AGGTTCCATT GTGAATGTGG GCAGCAAACG CTATCACATG GGTGACACTG CACCAATCAC AACTCCAAAA GCCGCGAATG GTACTTCTGC TCCCAAAAAA GCTGTCAATG GCGTCAGTGC CAGCAACAAG AGCTGCTTGT GGTTCGAAGA GGAGCTCGAA GAAGATCTGC GTTGGGTGTT TGGCGTCTCA AAGTGCGAAA GCTTTTCACT CTTCCTCATT TTATGTTGAT TTTATTTTCT AATTATTCTA GTTGAGAGGG AATGTCACTA TCAGTTTGGC ATCCTCTTGT ATCGAATCGT GATATTTAAC TGAGAGTGAT TCTTCTTCCT TGTCGCGCGA AAATTCCCTT GCTGTCTTGT GGACCGAGTG GTCCACATTC GTCTCTTAAC TGCAAGCAAT GAGCTGGGTC GGAAGCCATT CAACTGCAAA TATCAGTGAA GGCTATCTAT TCAGCTTACA TCCTGATCGA GATTGTCCCG TTCAGATTCC ACACAAGGTT GAAGATTCAA TTGTCTACTG GAGTATCAGT CTTCATGAGA GACTTACTTC TGTGCATCCA TAACGTCGTG ACAGTTTTAA TGATGTCCCT CTGATCCGTC ATAGGGAGAA GGAGAATAAT TTTGGGAGAA TACTTTTAGT TTCTTTTTCC GGGGTGCATA AGGATTTATG CTTTCTACCG TGAACCTATG CATTGTACTT CAATAACTTT TGTATGAGCT GATCTCAAAT CCAACATTTG TACGGAGATT CGCTCCCTCC TGACCTGAGC ACGTGCACAT GTGTTTTTTT GTTTTGTGTA TTACTTCTAT ACAAGCAGCA CATCTGATGC TCTGCGGATT GGATTCTCCT GTTCAACCGT GCGTGCCGTC ACTGGTTCAT GCGCATGCAG TACGGATTGT CTACTGCGTG TTGTCCGTTT AGCTAATTGA CGATGTTTAG AACATCATTG AGTGAAGATT AATATCCTAC TGAAATAAGT CGTCTCTGTT TATCAGAATC TTGCACACCG GAGTTAGCGA GTTTCAAGAT ATTCAACTGG TCGAGAGCGG GCCCTTCGGA AAGGTATGCT TTTCCGTCTG CTTAGTCAGT CCCGCTGCGG CTTAAGCGTG AGTGTCTTCC GTTTGTTGGG TGTGAAGGAG ATTACCCTCT AACTCTCTAA CCTGACATTA ACGGAAATTT TGGAAAACGG TTTGTTACTT TTCCAGGTTC TGATTCTTGA TGGGAAGCTA CAGTCAGCTG AGGCCGATGA GTTCGTGTAT CACGAAAGCA TTATTCATCC AGCCATGTTG TATCACAAAG AGTGAGTTCT TATGGTGCAT GTTTACATTT GCCACTAGCC ACTGTAATTA CATAATATTA TAATCTGTAA ATTGCCCAAA GTCATCGTAG TCACAAATCT CAAATGCAGT TCTGGAGAAG CTATAGTGAA CTCACAGACT GCGTCGTGTA CTTTGATGTT ATGTTACCTG TTTAGTCTCT TTGAATGAGA TGTTTTTCCC GCAAATTGCA GCCCAAAGAA CGTGTTCATC ATGGGTGGAG GAGAAGGTTC CACTGCTAGA GAGGCCCTGA GGCACAAGAG TGCCAAGAAA GTGGTCATGT GTGATATTGA CAAGGTATGC TATTTCGTGG GTATGAATTG AATCCAGTCA AAAATGGAAT CTCGAATGGG CAGATGATCT GAGTGAAATT CGGATGAAAC ATCTAATTTG CTCCCCCATT TGTCCGACAG GAAGTGGTGG ATTTCTGCCG AGAGCATTTG TCCGTGAACT CGGAGGCCTT TAAGAGCCGT CGCCTGGAAC TCGTGATCGC CGATGCACGG TCAGTTAATA GACACTCTAC ATTTGATCTC TACTTATTCG TCCCTCTCCC TTGAGGAAAG GTAGACTAAC TAGTTTGTGC GGTTAAATCT CAGTGCTGAG TTGGAAAGGC GTGAAGAAAC ATTTGACATC ATTATCGGAG ATCTGGCCGA CCCTGTCGAC GGAGGTCCAT GCTATAGATT GTATACTCAA TCCTTTTACG AATCCGTTTT GAAGCCGAGA CTCGCCCCAG GAGGAATCTT GGTCACACAG GTCAGCTATT CGTTGGCGCT TGTCAAACGC AGTTTTGTTT ATATATTTTG TGAAACAATT CAGCCCGAAA AACTGTTTTT GCCTCCGAAC ATCACTGACT GCGGAATATT GATTTGGCGG CAGGCTGGGC CAGCAGGAAT TTTAACTCAC ACAGAGGTGT TTACGTCCAT TTACAACACT CTTCGACAAG TGTTCAAATG TAGGTTGATC TGAAAGTTCG AAGCGATCAA CTTTTTGTAC GTCCGCATTG TGGACTGTGT ACTACTGTCT GCTTTAAGAC GAAAGTCGGC TGAACGCTCA TGTATGTAGC TCATGTAGGT GAGCGGAAGA AATATCAATC CTGACGTAAG CTAGCCCGGA ATATTCTGCA GATGTTGTGC CTTATGCAGC CCACATCCCA TCGTACGCCG ACTCTTGGGG ATGGGTGATG GCATCCGACC ACCCATTTCC AGCATTCAAC GACGAAGAGA CCGATTCCAG GATCTCCAAG CGACTCACTG GAGATTTGCA ATTTCTGGAC GGTACAACGA TGAGCGCCCT CTTCGCTCTC AACAAGCACG TGAGAAAATC GTGAGTTTCC AATATCCTGC GGGGCCCGTC GTTGTTGCTC ATCCGACGCC AATCTGATTT TCTCGTGCTT TGATAGCAAA GGGAGGACTG TTCACCTTCT TGTGAGAATG TCAGCTGACT TGTAACGTTT TGCAGGTTGG CCCAGGAGTC TCACGTGTAC ACAGAGGAGA CTGCCCGCTT CATTCACGGA CATGGAACCA ATGCGAAATC CCATTAGAAG TGCCATCGAC CCTCAAATCC ATAGACAGAT GAGAACGTTT TTGACAGAAT TTTATGTACT GCTCAGCAGA TAATCCGTGC CTCCTCCCTT CCATCTTCAC CACTTCACTC TGTCATGCTG AAGGGGCACC CCGGCGCGTG ATCCTCGCCC ATTCAGACCT CATACATACC CTTCAGCTCG TAGAACAGTT GTGCTATATC GAATTCCGTG AGAGGAGGAT CATCTCGACA AGCTGTACTC GGCGCACTAG TAGCAGTAAG TTAGTAAGTC ATAAAGTGCT CGAGGCTTCA AGGAGTGCCA CCCGCGAACA ACAGGGCCTC CACATCCATC GAGCACTGAC AGCAGTAGTT GTAGCGGAAT TAGCGGCAAC AACAGGCGAA CGAGAGCTTG CCTGTTCTTT GGACAAAAGG TCACCATCAG CTCACCACCT GGTGGAGTCC ATTGTCCACC CAATACTATT TTGTATAATA AAGC |
mRNA UTR + CDS |
| >Mp8g03070.1 GGTCAGCTTC CTTGCTCCCG TCCTCGCTTG CTTTGTTTGG GAGGTTGTTG CTACCACTCT TCCAGCCGCA GCTCCTGCTC CTTCGCCAAC AACGCTCGCC GCTTTCCACG ACTCCTAGTC TTCGGGAATT TGCTTTTCTG CTGAAGCAAC AGGTCCACTT CTTTCGTGCA CTCGGCGAAA GCAGGGCCTC CTCACCTCCT GTTCCTCTCC TTGCAAGCCT TGTGTTGGAG TTCTCGTCTC TGAGCCGCTT CTAGACGTCC TGTCTGTGTT GTTTATTTCA AGCAGTCGGT GGAGGAATCG GGGAGTGTTG GTCAATTCGT TCGTCGTTTT CTCGCTGCAA TTGACCGTGA ACGGTCAGAG AGACCATTTC TGCTCTGTTT TCTTTCTTTA TTAAGTCTTC AGTATCCTGG TTGCCGCTGT TGTAACGTTG CTGCTTCGTT CGTTCGAATT CTCTCCTGTG AGCTCGTCAT CCTGTAAGTA AAGCTGGGGA AGGAAAGCCT CCCAGGTCGG GGAAAGGAAA GAGAGGACGA AATGGCTGAA GCCATTACGA CTACAACCAC GATTCACCTG AATGGTTCAG CTCCCACCAA AGGTTCCATT GTGAATGTGG GCAGCAAACG CTATCACATG GGTGACACTG CACCAATCAC AACTCCAAAA GCCGCGAATG GTACTTCTGC TCCCAAAAAA GCTGTCAATG GCGTCAGTGC CAGCAACAAG AGCTGCTTGT GGTTCGAAGA GGAGCTCGAA GAAGATCTGC GTTGGGTGTT TGGCGTCTCA AAAATCTTGC ACACCGGAGT TAGCGAGTTT CAAGATATTC AACTGGTCGA GAGCGGGCCC TTCGGAAAGG TTCTGATTCT TGATGGGAAG CTACAGTCAG CTGAGGCCGA TGAGTTCGTG TATCACGAAA GCATTATTCA TCCAGCCATG TTGTATCACA AAGACCCAAA GAACGTGTTC ATCATGGGTG GAGGAGAAGG TTCCACTGCT AGAGAGGCCC TGAGGCACAA GAGTGCCAAG AAAGTGGTCA TGTGTGATAT TGACAAGGAA GTGGTGGATT TCTGCCGAGA GCATTTGTCC GTGAACTCGG AGGCCTTTAA GAGCCGTCGC CTGGAACTCG TGATCGCCGA TGCACGTGCT GAGTTGGAAA GGCGTGAAGA AACATTTGAC ATCATTATCG GAGATCTGGC CGACCCTGTC GACGGAGGTC CATGCTATAG ATTGTATACT CAATCCTTTT ACGAATCCGT TTTGAAGCCG AGACTCGCCC CAGGAGGAAT CTTGGTCACA CAGGCTGGGC CAGCAGGAAT TTTAACTCAC ACAGAGGTGT TTACGTCCAT TTACAACACT CTTCGACAAG TGTTCAAATA TGTTGTGCCT TATGCAGCCC ACATCCCATC GTACGCCGAC TCTTGGGGAT GGGTGATGGC ATCCGACCAC CCATTTCCAG CATTCAACGA CGAAGAGACC GATTCCAGGA TCTCCAAGCG ACTCACTGGA GATTTGCAAT TTCTGGACGG TACAACGATG AGCGCCCTCT TCGCTCTCAA CAAGCACGTG AGAAAATCGT TGGCCCAGGA GTCTCACGTG TACACAGAGG AGACTGCCCG CTTCATTCAC GGACATGGAA CCAATGCGAA ATCCCATTAG AAGTGCCATC GACCCTCAAA TCCATAGACA GATGAGAACG TTTTTGACAG AATTTTATGT ACTGCTCAGC AGATAATCCG TGCCTCCTCC CTTCCATCTT CACCACTTCA CTCTGTCATG CTGAAGGGGC ACCCCGGCGC GTGATCCTCG CCCATTCAGA CCTCATACAT ACCCTTCAGC TCGTAGAACA GTTGTGCTAT ATCGAATTCC GTGAGAGGAG GATCATCTCG ACAAGCTGTA CTCGGCGCAC TAGTAGCAGT AAGTTAGTAA GTCATAAAGT GCTCGAGGCT TCAAGGAGTG CCACCCGCGA ACAACAGGGC CTCCACATCC ATCGAGCACT GACAGCAGTA GTTGTAGCGG AATTAGCGGC AACAACAGGC GAACGAGAGC TTGCCTGTTC TTTGGACAAA AGGTCACCAT CAGCTCACCA CCTGGTGGAG TCCATTGTCC ACCCAATACT ATTTTGTATA ATAAAGC |
CDS |
| >Mp8g03070.1 ATGGCTGAAG CCATTACGAC TACAACCACG ATTCACCTGA ATGGTTCAGC TCCCACCAAA GGTTCCATTG TGAATGTGGG CAGCAAACGC TATCACATGG GTGACACTGC ACCAATCACA ACTCCAAAAG CCGCGAATGG TACTTCTGCT CCCAAAAAAG CTGTCAATGG CGTCAGTGCC AGCAACAAGA GCTGCTTGTG GTTCGAAGAG GAGCTCGAAG AAGATCTGCG TTGGGTGTTT GGCGTCTCAA AAATCTTGCA CACCGGAGTT AGCGAGTTTC AAGATATTCA ACTGGTCGAG AGCGGGCCCT TCGGAAAGGT TCTGATTCTT GATGGGAAGC TACAGTCAGC TGAGGCCGAT GAGTTCGTGT ATCACGAAAG CATTATTCAT CCAGCCATGT TGTATCACAA AGACCCAAAG AACGTGTTCA TCATGGGTGG AGGAGAAGGT TCCACTGCTA GAGAGGCCCT GAGGCACAAG AGTGCCAAGA AAGTGGTCAT GTGTGATATT GACAAGGAAG TGGTGGATTT CTGCCGAGAG CATTTGTCCG TGAACTCGGA GGCCTTTAAG AGCCGTCGCC TGGAACTCGT GATCGCCGAT GCACGTGCTG AGTTGGAAAG GCGTGAAGAA ACATTTGACA TCATTATCGG AGATCTGGCC GACCCTGTCG ACGGAGGTCC ATGCTATAGA TTGTATACTC AATCCTTTTA CGAATCCGTT TTGAAGCCGA GACTCGCCCC AGGAGGAATC TTGGTCACAC AGGCTGGGCC AGCAGGAATT TTAACTCACA CAGAGGTGTT TACGTCCATT TACAACACTC TTCGACAAGT GTTCAAATAT GTTGTGCCTT ATGCAGCCCA CATCCCATCG TACGCCGACT CTTGGGGATG GGTGATGGCA TCCGACCACC CATTTCCAGC ATTCAACGAC GAAGAGACCG ATTCCAGGAT CTCCAAGCGA CTCACTGGAG ATTTGCAATT TCTGGACGGT ACAACGATGA GCGCCCTCTT CGCTCTCAAC AAGCACGTGA GAAAATCGTT GGCCCAGGAG TCTCACGTGT ACACAGAGGA GACTGCCCGC TTCATTCACG GACATGGAAC CAATGCGAAA TCCCATTAG |
Protein |
| >Mp8g03070.1 MAEAITTTTT IHLNGSAPTK GSIVNVGSKR YHMGDTAPIT TPKAANGTSA PKKAVNGVSA SNKSCLWFEE ELEEDLRWVF GVSKILHTGV SEFQDIQLVE SGPFGKVLIL DGKLQSAEAD EFVYHESIIH PAMLYHKDPK NVFIMGGGEG STAREALRHK SAKKVVMCDI DKEVVDFCRE HLSVNSEAFK SRRLELVIAD ARAELERREE TFDIIIGDLA DPVDGGPCYR LYTQSFYESV LKPRLAPGGI LVTQAGPAGI LTHTEVFTSI YNTLRQVFKY VVPYAAHIPS YADSWGWVMA SDHPFPAFND EETDSRISKR LTGDLQFLDG TTMSALFALN KHVRKSLAQE SHVYTEETAR FIHGHGTNAK SH |