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Origin and early evolution of the plant terpene synthase family.

Jia, Q., et al. · 2022 · PNAS   research

doi:10.1073/pnas.2100361119   PMID:35394876   PMC9169658

Linked genes (2)  2 core 0 peripheral

Gene ID	Name	Evidence / Role	Function (this paper)
Mp2g07200	MpTPS3	experimental subject	Liverwort TPS biochemically characterized as a monofunctional class II copalyl diphosphate synthase that stereoselectively produces ent-CPP, having lost class I (KS) activity. Cited as evidence of independent CPS subfunctionalization in liverworts during early plant terpene synthase evolution.
Mp7g00020	MpTPS5	experimental subject	Liverwort TPS characterized as a monofunctional class II diterpene cyclase that produces rearranged KPP (kaurene-type precursor) rather than CPP, illustrating product diversification after loss of class I activity. Demonstrates specialized class II catalysis in liverwort terpene metabolism.