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microRNA-mediated control of cell fate specification and patterning in Marchantia polymorpha.

Aguilar-Cruz A, Flores-Sandoval E, Xu Y, Yu Y, Gutiérrez-Ramos X, González-Rangel CY, Oltehua-López O, Dorantes-Acosta AE, Trujillo JT, Kato H, Ishizaki K, Mosher RA, Dolan L, Chen X, Grimanelli D, Haseloff J, Bowman JL, Arteaga-Vazquez MA. · 2026 · New Phytol   research

doi:10.1111/nph.71487   PMID:42572113

Linked genes (2)  2 core 0 peripheral

Gene ID Name Evidence / Role Function (this paper)
Mp1g24140 MpC3HDZ experimental subject Class III HD-Zip transcription factor forming a regulatory circuit with miR166. The miR166/C3HDZ module controls auxin synthesis and thereby cell identity, patterning and body plan, a role inferred to be ancestral to land plants.
Mp7g12090 MpDCL1a experimental subject DICER-LIKE 1 required for miRNA biogenesis in M. polymorpha, characterised through CRISPR-Cas9 loss-of-function mutants. Loss of MpDCL1a disrupts cell identity, patterning, meristem function and laminar expansion, indicating that DCL1-dependent miRNA control of development predates the bryophyte/tracheophyte split.