Mp1g12750



Description

Annotation

Database ID Description
Pfam PF02362 B3 DNA binding domain
ProSiteProfiles PS50863 B3 DNA-binding domain profile.
PANTHER PTHR31384:SF115 AUXIN RESPONSE FACTOR 6
PANTHER PTHR31384 AUXIN RESPONSE FACTOR 4-RELATED
MobiDBLite mobidb-lite consensus disorder prediction
Pfam PF02309 AUX/IAA family
SUPERFAMILY SSF101936 DNA-binding pseudobarrel domain
Gene3D G3DSA:2.30.30.1040 -
Gene3D G3DSA:2.40.330.10 -
ProSiteProfiles PS51745 PB1 domain profile.
SMART SM01019 B3_2
SUPERFAMILY SSF54277 CAD & PB1 domains
Coils Coil Coil
Gene3D G3DSA:3.10.20.90 -
Pfam PF06507 Auxin response factor
CDD cd10017 B3_DNA
GO GO:0005634 nucleus
GO GO:0009725 response to hormone
GO GO:0003677 DNA binding
GO GO:0006355 regulation of transcription, DNA-templated
GO GO:0005515 protein binding
MapolyID Mapoly0019s0045 -

Nomenclature

Gene symbol Product Transcript ID Status
MpARF1 Transcription factor, similarity to Arabidopsis activator ARFs. Published

Associated Literature (AI-based literature mining, Beta-version)

Transcription factor, similarity to Arabidopsis activator ARFs.; The M. polymorpha genome encodes three ARFs (MpARF1, MpARF2, and MpARF3). The three MpARFs have a structure common to typical ARFs, containing a B3-like DNA binding domain (DBD) and a protein-protein interaction motif, called domains III and IV (Figs 1A and S2). Between the DBD and domain III, MpARF1 harbors a glutamine-rich region, which is known as a feature of activator ARF members. Phylogenetic analysis showed that MpARF1 belonged to the clade A, which represents activator ARF proteins such as ARF5/MONOPTEROS (MP) of Arabidopsis. (from nomenclature)

16 core 11 peripheral

Flores-Sandoval E, Suzuki H, Lazner JA, Briginshaw LN, Fisher TJ, Romani F, Levins J, Hainiwa E, Kinami T, Imai Y, Yumoto E, Asahina M, Kohchi T, Nishihama R, Bowman JL. (2026) · Current biology : CB  research experimental subject
The single A-class ARF; Mparf1-kd shows MpARF1-mediated auxin responses antagonize both auxin production and MpARF2 expression in different domains.
de Roij M, Heijdra E, Lamers J, Nishihama R, Borst JW, Weijers D. (2026) · Nature communications  research experimental subject
Activating A-class auxin response factor. This study showed MpARF1 shares the conserved arginine-dependent degradation mechanism with MpARF2, but stabilizing MpARF1 had little effect on development or auxin response, so its proteolysis is functionally dispensable.
Rienstra, J., et al. (2025) · Proceeding of the National Academy of Sciences USA  research experimental subject
Functionally studied as the sole A-class positive effector of auxin transcription: alanine substitutions (R194, P197, R199) and B3-domain swaps were assayed for complementation of the Mparf1-4 null. RNA-seq showed Tak-1 responded to IAA (112 DEGs) while Mparf1 showed no auxin response, defining R194/P197/R199 as essential for its DNA-binding function.
Solé-Gil A, Sakai Y, Catarino B, Jones VAS, Youngstrom CE, Jordà-Segura J, Cheng CL, Dolan L, Ambrose BA, Ishizaki K, Blázquez MA, Agustí J. (2025) · Developmental cell  research experimental subject
Auxin response factor; in N. benthamiana agroinfiltration assays MpARF1 induces the proMpACL5::LUC reporter, linking auxin signaling to the thermospermine pathway.
de Roij M, Hernandez Garcia J, Das S, Borst JW, Weijers D. (2025) · Nature plants  research experimental subject
Experimentally studied. The A-class ARF MpARF1 protein is likewise shown to be unstable, and degradation-motif swap experiments confirm it shares the conserved degradation determinants characterized for MpARF2.

Transcript models

Transcript ID Location Sequences Extract region
Mp1g12750.1 chr1:12882032..12890074 (-) Gene /  mRNA /  CDS /  Protein
FASTA / GenBank (with flanking bases)

Expression Level powered by MBEX

Caution: MBEX data are analyzed based on the v7.1 genome.

Link to the original image in MBEX


Gene structure:

Sequences:

Gene UTR + CDS + intron

FASTA

mRNA UTR + CDS

FASTA

CDS

FASTA

Protein

FASTA


MarpolBase / Genome Informatics Lab. NIG.