Mp4g15890



Description

Annotation

Database ID Description
MobiDBLite mobidb-lite consensus disorder prediction
ProSitePatterns PS00107 Protein kinases ATP-binding region signature.
FunFam G3DSA:1.10.510.10:FF:000058 Receptor-like protein kinase FERONIA
PANTHER PTHR27003 OS07G0166700 PROTEIN
FunFam G3DSA:3.30.200.20:FF:000039 receptor-like protein kinase FERONIA
CDD cd12087 TM_EGFR-like
ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature.
Gene3D G3DSA:3.30.200.20 Phosphorylase Kinase; domain 1
CDD cd14066 STKc_IRAK
Gene3D G3DSA:2.60.120.430 -
ProSiteProfiles PS50011 Protein kinase domain profile.
SUPERFAMILY SSF56112 Protein kinase-like (PK-like)
Pfam PF07714 Protein tyrosine and serine/threonine kinase
Gene3D G3DSA:1.10.510.10 Transferase(Phosphotransferase) domain 1
FunFam G3DSA:2.60.120.430:FF:000007 FERONIA receptor-like kinase
Pfam PF12819 Malectin-like domain
SMART SM00220 serkin_6
KOG KOG1187 Serine/threonine protein kinase; [T]
MapolyID Mapoly0869s0001 -
GO GO:0046777 protein autophosphorylation
GO GO:0005524 ATP binding
GO GO:0005886 plasma membrane
GO GO:0004672 protein kinase activity
GO GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO GO:0009506 plasmodesma
GO GO:0006468 protein phosphorylation

Nomenclature

Gene symbol Product Transcript ID Status
MpFER Receptor-like kinase of the RLK-Pelle CrRLK1L subfamily Published
MpFERONIA/MpTHESEUS LRR-RLK Provisional

Associated Literature (AI-based literature mining, Beta-version)

The single CrRLK1L receptor kinase gene of M. polymorpha (also known as MpTHESEUS/MpTHE), characterized here as the ancestral member of the family. Knockdown (three independent amiR-MpFER lines, 10-20% of wild-type transcript) reduced thallus size, caused short bursting rhizoids and reduced male fertility (fewer and smaller antheridiophores), while CRISPR/Cas9 amorphic Mpfer knockout alleles showed far more severe loss of tissue integrity, reduced tissue stiffness and cell death, and MpFER overexpression disrupted epidermis, air-chamber and air-pore formation. proMpFER:trpVNS reporters show broad gametophyte expression including archegonia (not the egg cell), the zygote after fertilization, antheridia and sporophyte; AtFER could not complement Mpfer, indicating an ancestral, non-interchangeable role in cell expansion and cell-wall integrity maintenance.

4 core 3 peripheral

Jobe TO, Junior CGL, Stolze SC, Stephan L, Westermann J, Harzen A, Hülskamp M, Nakagami H, Boisson-Dernier A. (2026) · Plant & cell physiology  research experimental subject
FERONIA receptor-like kinase; multiomics of Mpfer mutants shows MpFER and MpMRI cooperate to repress transcriptional networks, linking cell-wall integrity to ABA responses.
Zhang, Y., et al. (2026) · Nature Plants  research experimental subject
The single Marchantia CrRLK1L receptor kinase, shown here to be the MpRALF1 receptor in spermatozoids. MpFER is enriched in antheridiophores (proMpFER:GUS) and the MpFER-Flag protein localizes to sperm flagella; CRISPR Mpfer knockouts and amiRNA Ri-MpFER lines had reduced sperm ROS and motility that MpRALF1 peptide could no longer rescue. MpFER binds MpRALF1 (pulldown with MBP-MpFERecd, luciferase complementation with MpFER-deltaC) preferentially via the peptide's N-terminal region and forms a complex with MpLLG (CoIP); the MpFER-G282A substitution did not affect MpRALF1 binding, indicating a binding mode distinct from angiosperm RALF23-FER-LLG2 and RALF4-ANX1/BUPS1-LLG3. Gene ID not printed in the paper: resolved from the paper's own MpFER-RT-F/R qPCR primers (Suppl. Table 2), which match Mp4g15890 exactly, in agreement with Mecchia et al. 2022.
Mecchia, M.A., et al. (2022) · Development  research experimental subject
The single CrRLK1L receptor kinase gene of M. polymorpha (also known as MpTHESEUS/MpTHE), characterized here as the ancestral member of the family. Knockdown (three independent amiR-MpFER lines, 10-20% of wild-type transcript) reduced thallus size, caused short bursting rhizoids and reduced male fertility (fewer and smaller antheridiophores), while CRISPR/Cas9 amorphic Mpfer knockout alleles showed far more severe loss of tissue integrity, reduced tissue stiffness and cell death, and MpFER overexpression disrupted epidermis, air-chamber and air-pore formation. proMpFER:trpVNS reporters show broad gametophyte expression including archegonia (not the egg cell), the zygote after fertilization, antheridia and sporophyte; AtFER could not complement Mpfer, indicating an ancestral, non-interchangeable role in cell expansion and cell-wall integrity maintenance.
Westermann, j., et al. (2019) · Current Biology  research experimental subject
The single FERONIA (FER) receptor-like kinase of M. polymorpha; an evolutionarily conserved RLK signalling module controls cell-wall integrity during tip growth, and Mpfer mutants lose rhizoid cell-wall integrity (almost no intact rhizoids).
Baez, L. A., et al. (2022) · Plant Molecular Biology  review citation background
Only CrRLK1L kinase orthologue in M. polymorpha; FERONIA ortholog

Transcript models

Transcript ID Location Sequences Extract region
Mp4g15890.1 chr4:21377018..21381706 (-) Gene /  mRNA /  CDS /  Protein
FASTA / GenBank (with flanking bases)

Expression Level powered by MBEX

Link to the original image in MBEX

Single-cell expression scRNA-seq atlas from Wang et al., 2023

Expression of Mp4g15890 across the single-cell RNA-seq atlas. Cluster identities (right) annotate the same UMAP used for the feature plot (left).

Feature plot of Mp4g15890 on UMAP
Feature plot (Seurat scale expression level).
UMAP cluster annotation
Cell-type annotation of the UMAP clusters.
Violin plot by developmental stage
Violin plot by stage. Expression across developmental time points (D0–D31).
Violin plot by cell cluster
Violin plot by cluster. Expression across cell clusters (1–21).

Gene structure:

Sequences:

Gene UTR + CDS + intron

FASTA

mRNA UTR + CDS

FASTA

CDS

FASTA

Protein

FASTA


MarpolBase / Genome Informatics Lab. NIG.