Mp2g16780



Description

Annotation

Database ID Description
CDD cd02187 beta_tubulin
Coils Coil Coil
FunFam G3DSA:1.10.287.600:FF:000002 Tubulin beta chain
FunFam G3DSA:3.30.1330.20:FF:000002 Tubulin beta chain
FunFam G3DSA:3.40.50.1440:FF:000005 Tubulin beta chain
Gene3D G3DSA:1.10.287.600 Helix hairpin bin
Gene3D G3DSA:3.30.1330.20 -
Gene3D G3DSA:3.40.50.1440 Tubulin/FtsZ, GTPase domain
KEGG K07375 tubulin beta
KOG KOG1375 Beta tubulin; [Z]
MobiDBLite mobidb-lite consensus disorder prediction
PANTHER PTHR11588 TUBULIN
PRINTS PR01161 Tubulin signature
PRINTS PR01163 Beta-tubulin signature
Pfam PF00091 Tubulin/FtsZ family, GTPase domain
Pfam PF03953 Tubulin C-terminal domain
ProSitePatterns PS00227 Tubulin subunits alpha, beta, and gamma signature.
ProSitePatterns PS00228 Tubulin-beta mRNA autoregulation signal.
SMART SM00864 Tubulin_4
SMART SM00865 Tubulin_C_4
SUPERFAMILY SSF52490 Tubulin nucleotide-binding domain-like
SUPERFAMILY SSF55307 Tubulin C-terminal domain-like
GO GO:0003924 GTPase activity
GO GO:0005200 structural constituent of cytoskeleton
GO GO:0007017 microtubule-based process
GO GO:0005525 GTP binding
GO GO:0000278 mitotic cell cycle
GO GO:0005874 microtubule
GO GO:0005737 cytoplasm
GO GO:0000226 microtubule cytoskeleton organization
MapolyID Mapoly0109s0019 -

Nomenclature

Gene symbol Product Transcript ID Status
MpTUB1 beta-tubulin Published

Associated Literature (AI-based literature mining)

beta-tubulin; To analyze microtubule function and cell division in Marchantia, the expression of four MpTUBs was compared and TUB1 was found to be most uniformly expressed in Marchantia polymorpha tissues. The live-cell microtubule marker MpTUB1-GFP was generated, which is expressed under the control of the MpEF1a promoter. The observed intimate cooperation of Marchantia polar organizers comprising TUB1 with preprophase bands provides insight into the evolution of division plane alignment control of land plants. BoGa ecotype: KM096549 (MpTUB1), KJ948115 (MpTUB4). Tak-1 ecotype: KM096547 (MpTUB1), KJ948116 (MpTUB2), KJ948117 (MpTUB3), KM096548 (MpTUB4). (from nomenclature)

1 core 5 peripheral

Buschmann, H., et al. (2016) · New Phytologist  research experimental subject
beta-tubulin (TUB1); cloned and characterized to study microtubule dynamics of the centrosome-like polar organizers (MTOCs) in M. polymorpha.
Bowman, J. L., et al. (2022) · Plant Cell  review citation comparator
Marchantia gene cited in Bowman et al. (2022) model-system review
Robinson, K., et al. (2024) · Journal of Experimental Botany  research experimental tool
Tubulin used as a GFP-MpTUB1 fusion microtubule marker to label cortical microtubule filaments in confocal imaging of transgenic gemmae.
Champion, C., et al. (2021) · PLoS Genetics  research experimental tool
Tubulin used as a GFP fusion reporter to visualize and quantify microtubule organization in wild-type versus wdl mutant rhizoids.
Bonfanti, A., et al. (2023) · PNAS  research experimental tool
GFP-MpTUB1 fusion serves as a microtubule marker to image cytoskeletal orientation and predict division planes.

Transcript models

Transcript ID Location Sequences Extract region
Mp2g16780.1 chr2:19271609..19274536 (+) Gene /  mRNA /  CDS /  Protein
FASTA / GenBank (with flanking bases)

Expression Level powered by MBEX

Link to the original image in MBEX

Single-cell expression scRNA-seq atlas from Wang et al., 2023

Expression of Mp2g16780 across the single-cell RNA-seq atlas. Cluster identities (right) annotate the same UMAP used for the feature plot (left).

Feature plot of Mp2g16780 on UMAP
Feature plot (Seurat scale expression level).
UMAP cluster annotation
Cell-type annotation of the UMAP clusters.
Violin plot by developmental stage
Violin plot by stage. Expression across developmental time points (D0–D31).
Violin plot by cell cluster
Violin plot by cluster. Expression across cell clusters (1–21).

Gene structure:

Sequences:

Gene UTR + CDS + intron

FASTA

mRNA UTR + CDS

FASTA

CDS

FASTA

Protein

FASTA

MarpolBase / Genome Informatics Lab. NIG.