Mp3g02320



Description

Annotation

Database ID Description
CDD cd00086 homeodomain
Coils Coil Coil
FunFam G3DSA:1.10.10.60:FF:000159 Homeobox-leucine zipper protein HAT5
Gene3D G3DSA:1.10.10.60 -
KEGG K09338 homeobox-leucine zipper protein
KOG KOG0483 Transcription factor HEX, contains HOX and HALZ domains; N-term missing; C-term missing; [K]
MobiDBLite mobidb-lite consensus disorder prediction
PANTHER PTHR24326 HOMEOBOX-LEUCINE ZIPPER PROTEIN
PRINTS PR00031 Lambda-repressor HTH signature
Pfam PF00046 Homeodomain
Pfam PF02183 Homeobox associated leucine zipper
ProSitePatterns PS00027 'Homeobox' domain signature.
ProSiteProfiles PS50071 'Homeobox' domain profile.
SMART SM00389 HOX_1
SUPERFAMILY SSF46689 Homeodomain-like
GO GO:0043565 sequence-specific DNA binding
GO GO:0005634 nucleus
GO GO:0003700 DNA-binding transcription factor activity
GO GO:0003677 DNA binding
GO GO:0006355 regulation of DNA-templated transcription
GO GO:0045893 positive regulation of DNA-templated transcription
GO GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
MapolyID Mapoly0007s0221 -

Nomenclature

Gene symbol Product Transcript ID Status
MpC1HDZ transcription factor, HD, homeodomain protein Published
MpHD3 transcription factor, HD, homeodomain protein Published

Associated Literature (AI-based literature mining)

MpC1HDZ is the sole Class I HD-Zip orthologue in M. polymorpha. Mpc1hdz loss-of-function mutants were more susceptible to Spodoptera frugiperda herbivory but more resistant to Phytophthora palmivora, and showed developmental defects (shortened gemma cups, reduced air pore density, absent surface papillae, loss of oil bodies), indicating a broad role for MpC1HDZ in epidermal cell differentiation and defense.

4 core 19 peripheral

Romani F, Farías S, Rojas AC, Florent SN, Carella P, Schornack S, Bowman JL, Federici F, Moreno JE. (2026) · Plant physiology  research experimental subject
MpC1HDZ is the sole Class I HD-Zip orthologue in M. polymorpha. Mpc1hdz loss-of-function mutants were more susceptible to Spodoptera frugiperda herbivory but more resistant to Phytophthora palmivora, and showed developmental defects (shortened gemma cups, reduced air pore density, absent surface papillae, loss of oil bodies), indicating a broad role for MpC1HDZ in epidermal cell differentiation and defense.
Zenker S, Wulf D, Meierhenrich A, Viehoever P, Becker S, Eisenhut M, Stracke R, Weisshaar B, Brautigam A. (2025) · Plant Physiology  research experimental subject
M. polymorpha HD-Zip I/II TF assayed by ampDAP-seq; yielded TFBM (A/C)ATNAT, representing the homeodomain family.
Jimenez-Aleman, G. H., et al. (2021) · Pharmaceuticals  research experimental subject
The Mpc1hdz mutant, impaired in oil body formation and thus defective in secondary metabolite accumulation, was tested in antiviral assays. Extracts still showed clear protective activity below cytotoxic doses, indicating the antiviral metabolite is independent of oil-body secondary metabolism.
Romani, F., et al. (2020) · Current Biology  research experimental subject
Class I HD-Zip transcription factor; master regulator of oil body cell differentiation/oil body formation. Mutants lack oil bodies and OE increases them; oil bodies serve as a defense against arthropod herbivores.
Mercadal J, Tremblay S, Kraska L, Hutten MA, Formosa-Jordan P. (2026) · Development  research citation background
Class I HD-Zip transcription factor cited as an activator of oil body cell specification, whose loss-of-function mutants lack oil body cells altogether. The study itself shows that oil body cell spacing in fossil and extant liverworts follows a local-activation/lateral-inhibition mechanism.

Transcript models

Transcript ID Location Sequences Extract region
Mp3g02320.1 chr3:2365560..2370273 (-) Gene /  mRNA /  CDS /  Protein
FASTA / GenBank (with flanking bases)

Expression Level powered by MBEX

Link to the original image in MBEX

Single-cell expression scRNA-seq atlas from Wang et al., 2023

Expression of Mp3g02320 across the single-cell RNA-seq atlas. Cluster identities (right) annotate the same UMAP used for the feature plot (left).

Feature plot of Mp3g02320 on UMAP
Feature plot (Seurat scale expression level).
UMAP cluster annotation
Cell-type annotation of the UMAP clusters.
Violin plot by developmental stage
Violin plot by stage. Expression across developmental time points (D0–D31).
Violin plot by cell cluster
Violin plot by cluster. Expression across cell clusters (1–21).

Gene structure:

Sequences:

Gene UTR + CDS + intron

FASTA

mRNA UTR + CDS

FASTA

CDS

FASTA

Protein

FASTA


MarpolBase / Genome Informatics Lab. NIG.