Mp5g08960



Description

Annotation

Database ID Description
SMART SM00185 arm_5
SUPERFAMILY SSF48371 ARM repeat
Pfam PF13646 HEAT repeats
Gene3D G3DSA:1.25.10.10 -
Gene3D G3DSA:3.40.50.300 -
SUPERFAMILY SSF48452 TPR-like
Gene3D G3DSA:1.25.40.10 Tetratricopeptide repeat domain
ProSiteProfiles PS50176 Armadillo/plakoglobin ARM repeat profile.
Pfam PF00514 Armadillo/beta-catenin-like repeat
PANTHER PTHR47249 VACUOLAR PROTEIN 8
Pfam PF00931 NB-ARC domain
SUPERFAMILY SSF52540 P-loop containing nucleoside triphosphate hydrolases
SMART SM00382 AAA_5
ProSiteProfiles PS50005 TPR repeat profile.
Coils Coil Coil
SMART SM00028 tpr_5
KOG KOG0166 Karyopherin (importin) alpha; N-term missing; [U]
KOG KOG0166 Karyopherin (importin) alpha; N-term missing; C-term missing; [U]
KOG KOG0553 TPR repeat-containing protein; C-term missing; [R]
KOG KOG4658 Apoptotic ATPase; C-term missing; [T]
KOG KOG0989 Replication factor C, subunit RFC4; C-term missing; [L]
MapolyID Mapoly0095s0062 -
GO GO:0043495 protein-membrane adaptor activity
GO GO:0071562 nucleus-vacuole junction assembly
GO GO:0043531 ADP binding
GO GO:0005515 protein binding
GO GO:0016887 ATP hydrolysis activity

Nomenclature

Gene symbol Product Transcript ID Status
MpNBS-LRR15 NBS genes Provisional

Associated Literature (AI-based literature mining, Beta-version)

NHAT-type resistance gene from M. polymorpha that was overexpressed in Nicotiana benthamiana leaves, where it induced a hypersensitive-response cell death. Confirms an immune/cell-death function for this gene, used as functional validation of bryophyte resistance-gene predictions.

1 core 0 peripheral

Dong, S., et al. (2025) · Nature Genetics  research experimental subject
NHAT-type resistance gene from M. polymorpha that was overexpressed in Nicotiana benthamiana leaves, where it induced a hypersensitive-response cell death. Confirms an immune/cell-death function for this gene, used as functional validation of bryophyte resistance-gene predictions.

Transcript models

Transcript ID Location Sequences Extract region
Mp5g08960.1 chr5:12082400..12089608 (+) Gene /  mRNA /  CDS /  Protein
FASTA / GenBank (with flanking bases)

Expression Level powered by MBEX

Link to the original image in MBEX

Single-cell expression scRNA-seq atlas from Wang et al., 2023

Expression of Mp5g08960 across the single-cell RNA-seq atlas. Cluster identities (right) annotate the same UMAP used for the feature plot (left).

Feature plot of Mp5g08960 on UMAP
Feature plot (Seurat scale expression level).
UMAP cluster annotation
Cell-type annotation of the UMAP clusters.
Violin plot by developmental stage
Violin plot by stage. Expression across developmental time points (D0–D31).
Violin plot by cell cluster
Violin plot by cluster. Expression across cell clusters (1–21).

Gene structure:

Sequences:

Gene UTR + CDS + intron

FASTA

mRNA UTR + CDS

FASTA

CDS

FASTA

Protein

FASTA

MarpolBase / Genome Informatics Lab. NIG.