Mp4g11820



Description

Annotation

Database ID Description
MobiDBLite mobidb-lite consensus disorder prediction
SUPERFAMILY SSF54277 CAD & PB1 domains
Pfam PF02362 B3 DNA binding domain
Gene3D G3DSA:2.40.330.10 -
Pfam PF02309 AUX/IAA family
SMART SM01019 B3_2
ProSiteProfiles PS51745 PB1 domain profile.
ProSiteProfiles PS50863 B3 DNA-binding domain profile.
Gene3D G3DSA:2.30.30.1040 -
SUPERFAMILY SSF101936 DNA-binding pseudobarrel domain
Pfam PF06507 Auxin response factor
Gene3D G3DSA:3.10.20.90 -
CDD cd10017 B3_DNA
PANTHER PTHR31384 AUXIN RESPONSE FACTOR 4-RELATED
PANTHER PTHR31384:SF102 AUXIN RESPONSE FACTOR 4
GO GO:0005634 nucleus
GO GO:0009725 response to hormone
GO GO:0003677 DNA binding
GO GO:0006355 regulation of transcription, DNA-templated
GO GO:0005515 protein binding
MapolyID Mapoly0011s0167 -

Nomenclature

Gene symbol Product Transcript ID Status
MpARF2 Transcription factor, similarity to Arabidopsis repressor ARFs. Published

Associated Literature (AI-based literature mining)

Repressive B-class auxin response factor and the core focus of the study. The authors found MpARF2 degradation occurs across all developmental stages and that its stabilization severely impairs development and auxin response throughout the Marchantia lifecycle, showing proteolysis is critically required for its function.

12 core 13 peripheral

Flores-Sandoval E, Suzuki H, Lazner JA, Briginshaw LN, Fisher TJ, Romani F, Levins J, Hainiwa E, Kinami T, Imai Y, Yumoto E, Asahina M, Kohchi T, Nishihama R, Bowman JL. (2026) · Current biology : CB  research experimental subject
B-class auxin response factor; Mparf2-kd shows MpARF2 is essential for meristem organization in the gametophyte. MpARF2 promotes auxin production by activating the YUCCA gene MpYUC2 in stem cells.
de Roij M, Heijdra E, Lamers J, Nishihama R, Borst JW, Weijers D. (2026) · Nature communications  research experimental subject
Repressive B-class auxin response factor and the core focus of the study. The authors found MpARF2 degradation occurs across all developmental stages and that its stabilization severely impairs development and auxin response throughout the Marchantia lifecycle, showing proteolysis is critically required for its function.
Janssen B, Romein R, van den Berg WAM, Lindhoud S, Borst JW, van Mierlo CPM. (2026) · FEBS Open Bio  research experimental subject
Auxin response factor that forms nuclear assemblies in vivo, possibly by liquid-liquid phase separation. The paper reports a three-step procedure yielding soluble, monomeric full-length MpARF2 and truncated variants, plus a preparation step giving reproducible in vitro phase separation.
Arfman K, Janssen BPJ, Romein R, van den Boom S, van der Woude M, Jansen L, Rademaker M, Hernández-García J, Ramalho JJ, Dipp-Álvarez M, de Roij M, Lamers J, Hohlbein J, Borst JW, Weijers D, van Mierlo CPM, Sprakel J. (2026) · Sci Adv  research experimental subject
Auxin response factor shown to form nanoscopic clusters in the nucleus rather than acting as a mono/oligomer or forming phase-separated condensates. Nanoclustering gives MpARF2 high-affinity, switch-like and sequence-specific DNA binding that neither of the other two modes provides.
Crespo, I., et al. (2025) · Structure 33: doi: 10.1016/j.str.2025.1002.1006  research experimental subject
Class B AUXIN RESPONSE FACTOR; its DNA-binding domain (DBD) structure/function shows DNA-binding preference more like class A AtARF5 than class B AtARF1 — insight into ARF DBD evolution.

Transcript models

Transcript ID Location Sequences Extract region
Mp4g11820.1 chr4:13070480..13077062 (-) Gene /  mRNA /  CDS /  Protein
FASTA / GenBank (with flanking bases)

Expression Level powered by MBEX

Caution: MBEX data are analyzed based on the v7.1r2 genome.

Link to the original image in MBEX


Gene structure:

Sequences:

Gene UTR + CDS + intron

FASTA

mRNA UTR + CDS

FASTA

CDS

FASTA

Protein

FASTA

MarpolBase / Genome Informatics Lab. NIG.