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Redox buffering and H2O2 orchestrate the vegetative development of Marchantia polymorpha.

Kock C, Helmig J, Gutsche N, Dierschke T, Müller-Schüssele SJ, Zachgo S. · 2025 · The Plant journal : for cell and molecular biology   research

doi:10.1111/tpj.70317   PMID:40680301   PMC12274077

Linked genes (6)  2 core 4 peripheral

Gene ID Name Evidence / Role Function (this paper)
Mp5g18050 MpCLE2 experimental subject Exogenous application of the MpCLE2 peptide (MpCLE2p) expanded the meristem/stem cell zone and altered redox dynamics, linking MpCLE2 signaling to H2O2/redox-dependent control of cell proliferation.
Mp1g07310 MpGSH1 missing experimental subject Knockdown lines of MpGSH1, the sole gamma-glutamylcysteine synthetase gene, were generated by artificial miRNA. Reduced GSH levels impaired meristem development, showing MpGSH1-dependent glutathione redox buffering is essential for vegetative growth and meristem maintenance.
Mp7g01530 MpTCP1 missing citation comparator Cited as a redox-related bHLH transcription factor whose mutants show elevated H2O2, supporting the role of ROS in M. polymorpha growth.
— MpEF1a missing experimental tool The MpEF1alpha promoter was used to drive constitutive expression of the roGFP2-hGrx1 redox sensor in transgenic lines.
Mp1g26670 MpMIR160 experimental tool The MpMIR160 precursor served as the artificial microRNA scaffold for constructing the MpGSH1 knockdown vector.
— MpPLT missing citation background Cited transcription factor mentioned in the context of redox-dependent growth control.